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In this thesis I introduce a new direction to computing using nonlinear chaotic dynamics. The main idea is rich dynamics of a chaotic system enables us to (1) build better computers that have a flexible instruction set, and (2) carry out computation that conventional computers are not good at it.

In this thesis I introduce a new direction to computing using nonlinear chaotic dynamics. The main idea is rich dynamics of a chaotic system enables us to (1) build better computers that have a flexible instruction set, and (2) carry out computation that conventional computers are not good at it. Here I start from the theory, explaining how one can build a computing logic block using a chaotic system, and then I introduce a new theoretical analysis for chaos computing. Specifically, I demonstrate how unstable periodic orbits and a model based on them explains and predicts how and how well a chaotic system can do computation. Furthermore, since unstable periodic orbits and their stability measures in terms of eigenvalues are extractable from experimental times series, I develop a time series technique for modeling and predicting chaos computing from a given time series of a chaotic system. After building a theoretical framework for chaos computing I proceed to architecture of these chaos-computing blocks to build a sophisticated computing system out of them. I describe how one can arrange and organize these chaos-based blocks to build a computer. I propose a brand new computer architecture using chaos computing, which shifts the limits of conventional computers by introducing flexible instruction set. Our new chaos based computer has a flexible instruction set, meaning that the user can load its desired instruction set to the computer to reconfigure the computer to be an implementation for the desired instruction set. Apart from direct application of chaos theory in generic computation, the application of chaos theory to speech processing is explained and a novel application for chaos theory in speech coding and synthesizing is introduced. More specifically it is demonstrated how a chaotic system can model the natural turbulent flow of the air in the human speech production system and how chaotic orbits can be used to excite a vocal tract model. Also as another approach to build computing system based on nonlinear system, the idea of Logical Stochastic Resonance is studied and adapted to an autoregulatory gene network in the bacteriophage λ.
ContributorsKia, Behnam (Author) / Ditto, William (Thesis advisor) / Huang, Liang (Committee member) / Lai, Ying-Cheng (Committee member) / Helms Tillery, Stephen (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups

Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups or graphs. In this thesis, I first propose to solve a sparse learning model with a general group structure, where the predefined groups may overlap with each other. Then, I present three real world applications which can benefit from the group structured sparse learning technique. In the first application, I study the Alzheimer's Disease diagnosis problem using multi-modality neuroimaging data. In this dataset, not every subject has all data sources available, exhibiting an unique and challenging block-wise missing pattern. In the second application, I study the automatic annotation and retrieval of fruit-fly gene expression pattern images. Combined with the spatial information, sparse learning techniques can be used to construct effective representation of the expression images. In the third application, I present a new computational approach to annotate developmental stage for Drosophila embryos in the gene expression images. In addition, it provides a stage score that enables one to more finely annotate each embryo so that they are divided into early and late periods of development within standard stage demarcations. Stage scores help us to illuminate global gene activities and changes much better, and more refined stage annotations improve our ability to better interpret results when expression pattern matches are discovered between genes.
ContributorsYuan, Lei (Author) / Ye, Jieping (Thesis advisor) / Wang, Yalin (Committee member) / Xue, Guoliang (Committee member) / Kumar, Sudhir (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Complex dynamical systems consisting interacting dynamical units are ubiquitous in nature and society. Predicting and reconstructing nonlinear dynamics of units and the complex interacting networks among them serves the base for the understanding of a variety of collective dynamical phenomena. I present a general method to address the two outstanding

Complex dynamical systems consisting interacting dynamical units are ubiquitous in nature and society. Predicting and reconstructing nonlinear dynamics of units and the complex interacting networks among them serves the base for the understanding of a variety of collective dynamical phenomena. I present a general method to address the two outstanding problems as a whole based solely on time-series measurements. The method is implemented by incorporating compressive sensing approach that enables an accurate reconstruction of complex dynamical systems in terms of both nodal equations that determines the self-dynamics of units and detailed coupling patterns among units. The representative advantages of the approach are (i) the sparse data requirement which allows for a successful reconstruction from limited measurements, and (ii) general applicability to identical and nonidentical nodal dynamics, and to networks with arbitrary interacting structure, strength and sizes. Another two challenging problem of significant interest in nonlinear dynamics: (i) predicting catastrophes in nonlinear dynamical systems in advance of their occurrences and (ii) predicting the future state for time-varying nonlinear dynamical systems, can be formulated and solved in the framework of compressive sensing using only limited measurements. Once the network structure can be inferred, the dynamics behavior on them can be investigated, for example optimize information spreading dynamics, suppress cascading dynamics and traffic congestion, enhance synchronization, game dynamics, etc. The results can yield insights to control strategies design in the real-world social and natural systems. Since 2004, there has been a tremendous amount of interest in graphene. The most amazing feature of graphene is that there exists linear energy-momentum relationship when energy is low. The quasi-particles inside the system can be treated as chiral, massless Dirac fermions obeying relativistic quantum mechanics. Therefore, the graphene provides one perfect test bed to investigate relativistic quantum phenomena, such as relativistic quantum chaotic scattering and abnormal electron paths induced by klein tunneling. This phenomenon has profound implications to the development of graphene based devices that require stable electronic properties.
ContributorsYang, Rui (Author) / Lai, Ying-Cheng (Thesis advisor) / Duman, Tolga M. (Committee member) / Akis, Richard (Committee member) / Huang, Liang (Committee member) / Arizona State University (Publisher)
Created2012
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Description
What can classical chaos do to quantum systems is a fundamental issue highly relevant to a number of branches in physics. The field of quantum chaos has been active for three decades, where the focus was on non-relativistic quantumsystems described by the Schr¨odinger equation. By developing an efficient method to

What can classical chaos do to quantum systems is a fundamental issue highly relevant to a number of branches in physics. The field of quantum chaos has been active for three decades, where the focus was on non-relativistic quantumsystems described by the Schr¨odinger equation. By developing an efficient method to solve the Dirac equation in the setting where relativistic particles can tunnel between two symmetric cavities through a potential barrier, chaotic cavities are found to suppress the spread in the tunneling rate. Tunneling rate for any given energy assumes a wide range that increases with the energy for integrable classical dynamics. However, for chaotic underlying dynamics, the spread is greatly reduced. A remarkable feature, which is a consequence of Klein tunneling, arise only in relativistc quantum systems that substantial tunneling exists even for particle energy approaching zero. Similar results are found in graphene tunneling devices, implying high relevance of relativistic quantum chaos to the development of such devices. Wave propagation through random media occurs in many physical systems, where interesting phenomena such as branched, fracal-like wave patterns can arise. The generic origin of these wave structures is currently a matter of active debate. It is of fundamental interest to develop a minimal, paradigmaticmodel that can generate robust branched wave structures. In so doing, a general observation in all situations where branched structures emerge is non-Gaussian statistics of wave intensity with an algebraic tail in the probability density function. Thus, a universal algebraic wave-intensity distribution becomes the criterion for the validity of any minimal model of branched wave patterns. Coexistence of competing species in spatially extended ecosystems is key to biodiversity in nature. Understanding the dynamical mechanisms of coexistence is a fundamental problem of continuous interest not only in evolutionary biology but also in nonlinear science. A continuous model is proposed for cyclically competing species and the effect of the interplay between the interaction range and mobility on coexistence is investigated. A transition from coexistence to extinction is uncovered with a non-monotonic behavior in the coexistence probability and switches between spiral and plane-wave patterns arise. Strong mobility can either promote or hamper coexistence, while absent in lattice-based models, can be explained in terms of nonlinear partial differential equations.
ContributorsNi, Xuan (Author) / Lai, Ying-Cheng (Thesis advisor) / Huang, Liang (Committee member) / Yu, Hongbin (Committee member) / Akis, Richard (Committee member) / Arizona State University (Publisher)
Created2012
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Description
This dissertation constructs a new computational processing framework to robustly and precisely quantify retinotopic maps based on their angle distortion properties. More generally, this framework solves the problem of how to robustly and precisely quantify (angle) distortions of noisy or incomplete (boundary enclosed) 2-dimensional surface to surface mappings. This framework

This dissertation constructs a new computational processing framework to robustly and precisely quantify retinotopic maps based on their angle distortion properties. More generally, this framework solves the problem of how to robustly and precisely quantify (angle) distortions of noisy or incomplete (boundary enclosed) 2-dimensional surface to surface mappings. This framework builds upon the Beltrami Coefficient (BC) description of quasiconformal mappings that directly quantifies local mapping (circles to ellipses) distortions between diffeomorphisms of boundary enclosed plane domains homeomorphic to the unit disk. A new map called the Beltrami Coefficient Map (BCM) was constructed to describe distortions in retinotopic maps. The BCM can be used to fully reconstruct the original target surface (retinal visual field) of retinotopic maps. This dissertation also compared retinotopic maps in the visual processing cascade, which is a series of connected retinotopic maps responsible for visual data processing of physical images captured by the eyes. By comparing the BCM results from a large Human Connectome project (HCP) retinotopic dataset (N=181), a new computational quasiconformal mapping description of the transformed retinal image as it passes through the cascade is proposed, which is not present in any current literature. The description applied on HCP data provided direct visible and quantifiable geometric properties of the cascade in a way that has not been observed before. Because retinotopic maps are generated from in vivo noisy functional magnetic resonance imaging (fMRI), quantifying them comes with a certain degree of uncertainty. To quantify the uncertainties in the quantification results, it is necessary to generate statistical models of retinotopic maps from their BCMs and raw fMRI signals. Considering that estimating retinotopic maps from real noisy fMRI time series data using the population receptive field (pRF) model is a time consuming process, a convolutional neural network (CNN) was constructed and trained to predict pRF model parameters from real noisy fMRI data
ContributorsTa, Duyan Nguyen (Author) / Wang, Yalin (Thesis advisor) / Lu, Zhong-Lin (Committee member) / Hansford, Dianne (Committee member) / Liu, Huan (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Retinotopic map, the map between visual inputs on the retina and neuronal activation in brain visual areas, is one of the central topics in visual neuroscience. For human observers, the map is typically obtained by analyzing functional magnetic resonance imaging (fMRI) signals of cortical responses to slowly moving visual stimuli

Retinotopic map, the map between visual inputs on the retina and neuronal activation in brain visual areas, is one of the central topics in visual neuroscience. For human observers, the map is typically obtained by analyzing functional magnetic resonance imaging (fMRI) signals of cortical responses to slowly moving visual stimuli on the retina. Biological evidences show the retinotopic mapping is topology-preserving/topological (i.e. keep the neighboring relationship after human brain process) within each visual region. Unfortunately, due to limited spatial resolution and the signal-noise ratio of fMRI, state of art retinotopic map is not topological. The topic was to model the topology-preserving condition mathematically, fix non-topological retinotopic map with numerical methods, and improve the quality of retinotopic maps. The impose of topological condition, benefits several applications. With the topological retinotopic maps, one may have a better insight on human retinotopic maps, including better cortical magnification factor quantification, more precise description of retinotopic maps, and potentially better exam ways of in Ophthalmology clinic.
ContributorsTu, Yanshuai (Author) / Wang, Yalin (Thesis advisor) / Lu, Zhong-Lin (Committee member) / Crook, Sharon (Committee member) / Yang, Yezhou (Committee member) / Zhang, Yu (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Beta-Amyloid(Aβ) plaques and tau protein tangles in the brain are now widely recognized as the defining hallmarks of Alzheimer’s disease (AD), followed by structural atrophy detectable on brain magnetic resonance imaging (MRI) scans. However, current methods to detect Aβ/tau pathology are either invasive (lumbar puncture) or quite costly and not

Beta-Amyloid(Aβ) plaques and tau protein tangles in the brain are now widely recognized as the defining hallmarks of Alzheimer’s disease (AD), followed by structural atrophy detectable on brain magnetic resonance imaging (MRI) scans. However, current methods to detect Aβ/tau pathology are either invasive (lumbar puncture) or quite costly and not widely available (positron emission tomography (PET)). And one of the particular neurodegenerative regions is the hippocampus to which the influence of Aβ/tau on has been one of the research projects focuses in the AD pathophysiological progress. In this dissertation, I proposed three novel machine learning and statistical models to examine subtle aspects of the hippocampal morphometry from MRI that are associated with Aβ /tau burden in the brain, measured using PET images. The first model is a novel unsupervised feature reduction model to generate a low-dimensional representation of hippocampal morphometry for each individual subject, which has superior performance in predicting Aβ/tau burden in the brain. The second one is an efficient federated group lasso model to identify the hippocampal subregions where atrophy is strongly associated with abnormal Aβ/Tau. The last one is a federated model for imaging genetics, which can identify genetic and transcriptomic influences on hippocampal morphometry. Finally, I stated the results of these three models that have been published or submitted to peer-reviewed conferences and journals.
ContributorsWu, Jianfeng (Author) / Wang, Yalin (Thesis advisor) / Li, Baoxin (Committee member) / Liang, Jianming (Committee member) / Wang, Junwen (Committee member) / Wu, Teresa (Committee member) / Arizona State University (Publisher)
Created2022
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Description
A remarkable phenomenon in contemporary physics is quantum scarring in classically chaoticsystems, where the wave functions tend to concentrate on classical periodic orbits. Quantum scarring has been studied for more than four decades, but the problem of efficiently detecting quantum scars has remained to be challenging, relying mostly on human visualization of wave

A remarkable phenomenon in contemporary physics is quantum scarring in classically chaoticsystems, where the wave functions tend to concentrate on classical periodic orbits. Quantum scarring has been studied for more than four decades, but the problem of efficiently detecting quantum scars has remained to be challenging, relying mostly on human visualization of wave function patterns. This paper develops a machine learning approach to detecting quantum scars in an automated and highly efficient manner. In particular, this paper exploits Meta learning. The first step is to construct a few-shot classification algorithm, under the requirement that the one-shot classification accuracy be larger than 90%. Then propose a scheme based on a combination of neural networks to improve the accuracy. This paper shows that the machine learning scheme can find the correct quantum scars from thousands images of wave functions, without any human intervention, regardless of the symmetry of the underlying classical system. This will be the first application of Meta learning to quantum systems. Interacting spin networks are fundamental to quantum computing. Data-based tomography oftime-independent spin networks has been achieved, but an open challenge is to ascertain the structures of time-dependent spin networks using time series measurements taken locally from a small subset of the spins. Physically, the dynamical evolution of a spin network under time-dependent driving or perturbation is described by the Heisenberg equation of motion. Motivated by this basic fact, this paper articulates a physics-enhanced machine learning framework whose core is Heisenberg neural networks. This paper demonstrates that, from local measurements, not only the local Hamiltonian can be recovered but the Hamiltonian reflecting the interacting structure of the whole system can also be faithfully reconstructed. Using Heisenberg neural machine on spin networks of a variety of structures. In the extreme case where measurements are taken from only one spin, the achieved tomography fidelity values can reach about 90%. The developed machine learning framework is applicable to any time-dependent systems whose quantum dynamical evolution is governed by the Heisenberg equation of motion.
ContributorsHan, Chendi (Author) / Lai, Ying-Cheng (Thesis advisor) / Yu, Hongbin (Committee member) / Dasarathy, Gautam (Committee member) / Seo, Jae-Sun (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Few-layer black phosphorous (FLBP) is one of the most important two-dimensional (2D) materials due to its strongly layer-dependent quantized bandstructure, which leads to wavelength-tunable optical and electrical properties. This thesis focuses on the preparation of stable, high-quality FLBP, the characterization of its optical properties, and device applications.Part I presents an

Few-layer black phosphorous (FLBP) is one of the most important two-dimensional (2D) materials due to its strongly layer-dependent quantized bandstructure, which leads to wavelength-tunable optical and electrical properties. This thesis focuses on the preparation of stable, high-quality FLBP, the characterization of its optical properties, and device applications.Part I presents an approach to preparing high-quality, stable FLBP samples by combining O2 plasma etching, boron nitride (BN) sandwiching, and subsequent rapid thermal annealing (RTA). Such a strategy has successfully produced FLBP samples with a record-long lifetime, with 80% of photoluminescence (PL) intensity remaining after 7 months. The improved material quality of FLBP allows the establishment of a more definitive relationship between the layer number and PL energies. Part II presents the study of oxygen incorporation in FLBP. The natural oxidation formed in the air environment is dominated by the formation of interstitial oxygen and dangling oxygen. By the real-time PL and Raman spectroscopy, it is found that continuous laser excitation breaks the bonds of interstitial oxygen, and free oxygen atoms can diffuse around or form dangling oxygen under low heat. RTA at 450 °C can turn the interstitial oxygen into dangling oxygen more thoroughly. Such oxygen-containing samples show similar optical properties to the pristine BP samples. The bandgap of such FLBP samples increases with the concentration of the incorporated oxygen. Part III deals with the investigation of emission natures of the prepared samples. The power- and temperature-dependent measurements demonstrate that PL emissions are dominated by excitons and trions, with a combined percentage larger than 80% at room temperature. Such measurements allow the determination of trion and exciton binding energies of 2-, 3-, and 4-layer BP, with values around 33, 23, 15 meV for trions and 297, 276, 179 meV for excitons at 77K, respectively. Part IV presents the initial exploration of device applications of such FLBP samples. The coupling between photonic crystal cavity (PCC) modes and FLBP's emission is realized by integrating the prepared sandwich structure onto 2D PCC. Electroluminescence has also been achieved by integrating such materials onto interdigital electrodes driven by alternating electric fields.
ContributorsLi, Dongying (Author) / Ning, Cun-Zheng (Thesis advisor) / Vasileska, Dragica (Committee member) / Lai, Ying-Cheng (Committee member) / Yu, Hongbin (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Statistical Shape Modeling is widely used to study the morphometrics of deformable objects in computer vision and biomedical studies. There are mainly two viewpoints to understand the shapes. On one hand, the outer surface of the shape can be taken as a two-dimensional embedding in space. On the other hand,

Statistical Shape Modeling is widely used to study the morphometrics of deformable objects in computer vision and biomedical studies. There are mainly two viewpoints to understand the shapes. On one hand, the outer surface of the shape can be taken as a two-dimensional embedding in space. On the other hand, the outer surface along with its enclosed internal volume can be taken as a three-dimensional embedding of interests. Most studies focus on the surface-based perspective by leveraging the intrinsic features on the tangent plane. But a two-dimensional model may fail to fully represent the realistic properties of shapes with both intrinsic and extrinsic properties. In this thesis, severalStochastic Partial Differential Equations (SPDEs) are thoroughly investigated and several methods are originated from these SPDEs to try to solve the problem of both two-dimensional and three-dimensional shape analyses. The unique physical meanings of these SPDEs inspired the findings of features, shape descriptors, metrics, and kernels in this series of works. Initially, the data generation of high-dimensional shapes, here, the tetrahedral meshes, is introduced. The cerebral cortex is taken as the study target and an automatic pipeline of generating the gray matter tetrahedral mesh is introduced. Then, a discretized Laplace-Beltrami operator (LBO) and a Hamiltonian operator (HO) in tetrahedral domain with Finite Element Method (FEM) are derived. Two high-dimensional shape descriptors are defined based on the solution of the heat equation and Schrödinger’s equation. Considering the fact that high-dimensional shape models usually contain massive redundancies, and the demands on effective landmarks in many applications, a Gaussian process landmarking on tetrahedral meshes is further studied. A SIWKS-based metric space is used to define a geometry-aware Gaussian process. The study of the periodic potential diffusion process further inspired the idea of a new kernel call the geometry-aware convolutional kernel. A series of Bayesian learning methods are then introduced to tackle the problem of shape retrieval and classification. Experiments of every single item are demonstrated. From the popular SPDE such as the heat equation and Schrödinger’s equation to the general potential diffusion equation and the specific periodic potential diffusion equation, it clearly shows that classical SPDEs play an important role in discovering new features, metrics, shape descriptors and kernels. I hope this thesis could be an example of using interdisciplinary knowledge to solve problems.
ContributorsFan, Yonghui (Author) / Wang, Yalin (Thesis advisor) / Lepore, Natasha (Committee member) / Turaga, Pavan (Committee member) / Yang, Yezhou (Committee member) / Arizona State University (Publisher)
Created2021