Matching Items (232)
Filtering by

Clear all filters

152747-Thumbnail Image.png
Description
ABSTRACT The hormone leptin is an important regulator of body weight and energy balance, while nitric oxide (NO) produced in the blood vessels is beneficial for preventing disease-induced impaired vasodilation and hypertension. Elevations in the free radical superoxide can result in impaired vasodilation through scavenging of NO. Omega 3 is

ABSTRACT The hormone leptin is an important regulator of body weight and energy balance, while nitric oxide (NO) produced in the blood vessels is beneficial for preventing disease-induced impaired vasodilation and hypertension. Elevations in the free radical superoxide can result in impaired vasodilation through scavenging of NO. Omega 3 is a polyunsaturated fatty acid that is beneficial at reducing body weight and in lowering many cardiovascular risk factors like atherosclerosis. The present study was designed to examine the change in plasma concentrations of leptin, nitric oxide, and the antioxidant superoxide dismutase in addition to examining the association between leptin and NO in healthy normal weight adult female subjects before and following omega 3 intakes. Participants were randomly assigned to either a fish oil group (600 mg per day) or a control group (1000 mg of coconut oil per day) for 8 weeks. Results showed no significant difference in the percent change of leptin over the 8 week supplementation period for either group (15.3±31.9 for fish oil group, 7.83±27 for control group; p=0.763). The percent change in NO was similarly not significantly altered in either group (-1.97±22 decline in fish oil group, 11.8±53.9 in control group; p=0.960). Likewise, the percent change in superoxide dismutase for each group was not significant following 8 weeks of supplementation (fish oil group: 11.94±20.94; control group: 11.8±53.9; p=0.362). The Pearson correlation co-efficient comparing the percent change of both leptin and NO was r2= -0.251 demonstrating a mildly negative, albeit insignificant, relationship between these factors. Together, these findings suggest that daily supplementation with 600 mg omega 3 in healthy females is not beneficial for improving these cardiovascular risk markers. Future studies in this area should include male subjects as well as overweight subjects with larger doses of fish oil that are equivalent to three or more servings per week. The importance of gender cannot be underestimated since estrogen has protective effects in the vasculature of females that may have masked any further protective effects of the fish oil. In addition, overweight individuals are often leptin-resistant and develop impaired vasodilation resulting from superoxide-mediated scavenging of nitric oxide. Therefore, the reported antioxidant and weight loss properties of omega 3 supplementation may greatly benefit overweight individuals.
ContributorsAlanbagy, Samer (Author) / Sweazea, Karen (Thesis advisor) / Johnston, Carol (Committee member) / Shepard, Christina (Committee member) / Lespron, Christy (Committee member) / Arizona State University (Publisher)
Created2014
Description
The omega-3 fatty acids in fatty fish and fish oil, eicosapentanoic acid (EPA) and docosahexanoic acid (DHA), have been associated with a reduction in risk for cardiovascular disease. Blood type is a known contributor to risk for cardiovascular events. This study evaluated the effect of fish oil supplements on cardiovascular

The omega-3 fatty acids in fatty fish and fish oil, eicosapentanoic acid (EPA) and docosahexanoic acid (DHA), have been associated with a reduction in risk for cardiovascular disease. Blood type is a known contributor to risk for cardiovascular events. This study evaluated the effect of fish oil supplements on cardiovascular risk markers in adults with blood types A or O. An 8-week parallel-arm, randomized, double-blind trial was conducted in healthy adult men and women with either blood type A (BTA) or blood type O (BTO). Participants were randomized to receive fish oil supplements (n=10 [3 BTA/7 BTO]; 2 g [containing 1.2 g EPA+DHA]/d) or a coconut oil supplement (n=7 [3 BTA/4 BTO]; 2 g/d). Markers that were examined included total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), high-sensitivity C-reactive protein (hsCRP), and hemoglobin A1C (HbA1C). Results indicated that the percent change in LDL cholesterol was significantly greater in the coconut oil group vs the fish oil group (-14.8±12.2% vs +2.8±18.9% respectively, p=0.048). There were no other significant differences between treatment groups, or between blood types A and O, for the other cardiovascular risk markers. Further research with a larger and more diverse sample may yield a more conclusive result.
ContributorsHerring, Dana (Author) / Johnston, Carol (Thesis advisor) / Vega-Lopez, Sonia (Committee member) / Shepard, Christina (Committee member) / Arizona State University (Publisher)
Created2014
152908-Thumbnail Image.png
Description
A new photovoltaic (PV) array power converter circuit is presented. The salient features of this inverter are: transformerless topology, grounded PV array, and only film capacitors. The motivations are to reduce cost, eliminate leakage ground currents, and improve reliability. The use of Silicon Carbide (SiC) transistors is the key enabling

A new photovoltaic (PV) array power converter circuit is presented. The salient features of this inverter are: transformerless topology, grounded PV array, and only film capacitors. The motivations are to reduce cost, eliminate leakage ground currents, and improve reliability. The use of Silicon Carbide (SiC) transistors is the key enabling technology for this particular circuit to attain good efficiency.

Traditionally, grid connected PV inverters required a transformer for isolation and safety. The disadvantage of high frequency transformer based inverters is complexity and cost. Transformerless inverters have become more popular recently, although they can be challenging to implement because of possible high frequency currents through the PV array's stay capacitance to earth ground. Conventional PV inverters also typically utilize electrolytic capacitors for bulk power buffering. However such capacitors can be prone to decreased reliability.

The solution proposed here to solve these problems is a bi directional buck boost converter combined with half bridge inverters. This configuration enables grounding of the array's negative terminal and passive power decoupling with only film capacitors.

Several aspects of the proposed converter are discussed. First a literature review is presented on the issues to be addressed. The proposed circuit is then presented and examined in detail. This includes theory of operation, component selection, and control systems. An efficiency analysis is also conducted. Simulation results are then presented that show correct functionality. A hardware prototype is built and experiment results also prove the concept. Finally some further developments are mentioned.

As a summary of the research a new topology and control technique were developed. The resultant circuit is a high performance transformerless PV inverter with upwards of 97% efficiency.
ContributorsBreazeale, Lloyd C (Author) / Ayyanar, Raja (Thesis advisor) / Karady, George G. (Committee member) / Tylavsky, Daniel (Committee member) / Tsakalis, Konstantinos (Committee member) / Arizona State University (Publisher)
Created2014
152865-Thumbnail Image.png
Description
As global energy demand has dramatically increased and traditional fossil fuels will be depleted in the foreseeable future, clean and unlimited renewable energies are recognized as the future global energy challenge solution. Today, the power grid in U.S. is building more and more renewable energies like wind and solar, while

As global energy demand has dramatically increased and traditional fossil fuels will be depleted in the foreseeable future, clean and unlimited renewable energies are recognized as the future global energy challenge solution. Today, the power grid in U.S. is building more and more renewable energies like wind and solar, while the electric power system faces new challenges from rapid growing percentage of wind and solar. Unlike combustion generators, intermittency and uncertainty are the inherent features of wind and solar. These features bring a big challenge to the stability of modern electric power grid, especially for a small scale power grid with wind and solar. In order to deal with the intermittency and uncertainty of wind and solar, energy storage systems are considered as one solution to mitigate the fluctuation of wind and solar by smoothing their power outputs. For many different types of energy storage systems, this thesis studied the operation of battery energy storage systems (BESS) in power systems and analyzed the benefits of the BESS. Unlike many researchers assuming fixed utilization patterns for BESS and calculating the benefits, this thesis found the BESS utilization patterns and benefits through an investment planning model. Furthermore, a cost is given for utilizing BESS and to find the best way of operating BESS rather than set an upper bound and a lower bound for BESS energy levels. Two planning models are proposed in this thesis and preliminary conclusions are derived from simulation results. This work is organized as below: chapter 1 briefly introduces the background of this research; chapter 2 gives an overview of previous related work in this area; the main work of this thesis is put in chapter 3 and chapter 4 contains the generic BESS model and the investment planning model; the following chapter 5 includes the simulation and results analysis of this research and chapter 6 provides the conclusions from chapter 5.
ContributorsDai, Daihong (Author) / Hedman, Kory W (Thesis advisor) / Zhang, Muhong (Committee member) / Ayyanar, Raja (Committee member) / Arizona State University (Publisher)
Created2014
152889-Thumbnail Image.png
Description
The unpleasant bitter taste found in many nutritious vegetables may deter their consumption. While bitterness suppression by prototypical tastants is well-studied in the chemical and pharmacological fields, mechanisms to reduce the bitterness of foods such as vegetables remain to be elucidated. Here tastants representing the taste primaries of

The unpleasant bitter taste found in many nutritious vegetables may deter their consumption. While bitterness suppression by prototypical tastants is well-studied in the chemical and pharmacological fields, mechanisms to reduce the bitterness of foods such as vegetables remain to be elucidated. Here tastants representing the taste primaries of salty and sweet were investigated as potential bitterness suppressors of three types of Brassicaceae vegetables. The secondary aim of these studies was to determine whether the bitter masking agents were differentially effective for bitter-sensitive and bitter-insensitive individuals. In all experiments, participants rated vegetables plain and with the addition of tastants. In Experiments 1-3, sucrose and NNS suppressed the bitterness of broccoli, Brussels sprouts, and cauliflower, whereas NaCl did not. Varying concentrations of NaCl and sucrose were introduced in Experiment 4 to assess the dose-dependency of the effects. While sucrose was a robust bitterness suppressor, NaCl suppressed bitterness only for participants who perceived the plain Brussels sprouts as highly bitter. Experiment 5, through the implementation of a rigorous control condition, determined that some but not all of this effect can be accounted for by regression to the mean. Individual variability in taste perception as determined by sampling of aqueous bitter, salty, and sweet solutions did not influence the degree of suppression by NaCl or sucrose. Consumption of vegetables is deterred by their bitter taste. Utilizing tastants to mask bitterness, a technique that preserves endogenous nutrients, can circumvent this issue. Sucrose is a robust bitter suppressor whereas the efficacy of NaCl is dependent upon bitterness perception of the plain vegetables.
ContributorsWilkie, Lynn Melissa (Author) / Capaldi Phillips, Elizabeth D (Thesis advisor) / Cohen, Adam (Committee member) / Johnston, Carol (Committee member) / Sanabria, Federico (Committee member) / Arizona State University (Publisher)
Created2014
153496-Thumbnail Image.png
Description
An important operating aspect of all transmission systems is power system stability

and satisfactory dynamic performance. The integration of renewable resources in general, and photovoltaic resources in particular into the grid has created new engineering issues. A particularly problematic operating scenario occurs when conventional generation is operated at a low level

An important operating aspect of all transmission systems is power system stability

and satisfactory dynamic performance. The integration of renewable resources in general, and photovoltaic resources in particular into the grid has created new engineering issues. A particularly problematic operating scenario occurs when conventional generation is operated at a low level but photovoltaic solar generation is at a high level. Significant solar photovoltaic penetration as a renewable resource is becoming a reality in some electric power systems. In this thesis, special attention is given to photovoltaic generation in an actual electric power system: increased solar penetration has resulted in significant strides towards meeting renewable portfolio standards. The impact of solar generation integration on power system dynamics is studied and evaluated.

This thesis presents the impact of high solar penetration resulting in potentially

problematic low system damping operating conditions. This is the case because the power system damping provided by conventional generation may be insufficient due to reduced system inertia and change in power flow patterns affecting synchronizing and damping capability in the AC system. This typically occurs because conventional generators are rescheduled or shut down to allow for the increased solar production. This problematic case may occur at any time of the year but during the springtime months of March-May, when the system load is low and the ambient temperature is relatively low, there is the potential that over voltages may occur in the high voltage transmission system. Also, reduced damping in system response to disturbances may occur. An actual case study is considered in which real operating system data are used. Solutions to low damping cases are discussed and a solution based on the retuning of a conventional power system stabilizer is given in the thesis.
ContributorsPethe, Anushree Sanjeev (Author) / Vittal, Vijay (Thesis advisor) / Heydt, Gerald T (Thesis advisor) / Ayyanar, Raja (Committee member) / Arizona State University (Publisher)
Created2015
153450-Thumbnail Image.png
Description
Diet quality is closely intertwined with overall health status and deserves close examination. Healthcare providers are stretched thin in the current stressed system and would benefit from a validated tool for rapid assessment of diet quality. The Rapid Eating and Activity Assessment for Participants Short Version (REAP-S) represents one such

Diet quality is closely intertwined with overall health status and deserves close examination. Healthcare providers are stretched thin in the current stressed system and would benefit from a validated tool for rapid assessment of diet quality. The Rapid Eating and Activity Assessment for Participants Short Version (REAP-S) represents one such option. The objective of the current study was to evaluate the effectiveness of the REAP-S and Healthy Eating Index 2010 (HEI-2010) for scoring the diet quality of omnivorous, vegetarian and vegan diets. Eighty-one healthy male and female subjects with an average age of 30.9 years completed the REAP-S as well as a 24-hour dietary recall. REAP-S and HEI-2010 scores were calculated for each subject and evaluated against each other using Spearman correlations and Chi Square. Further analysis was completed to compare diet quality scores of the HEI-2010 and REAP-S by tertiles to examine how closely these two tools score diet quality. The mean HEI-2010 score was 47.4/100 and the mean REAP-S score was 33.5/39. The correlation coefficient comparing the REAP-S to the HEI-2010 was 0.309 (p=0.005), and the REAP-S exhibited a precision of 44.4% to the HEI-2010 for diet quality. The REAP-S significantly correlated with the HEI-2010 for whole fruit (r=0.247, p=0.026), greens and beans (r=0.276, p=0.013), seafood proteins (r=0.298, p=0.007), and fatty acids (r=0.400, p<0.001). When evaluated by diet type, the REAP-S proved to have increased precision in plant-based diets, 50% for vegetarian and 52% for vegan, over omnivorous diets (32%). The REAP-S is a desirable tool to rapidly assess diet quality in the community setting as it is significantly correlated to the HEI-2010 and requires less time, labor and money to score and assess than the HEI-2010. More studies are needed to evaluate the precision and validity of REAP-S in a broader, more diverse population.
ContributorsBliss, Courtney (Author) / Johnston, Carol (Thesis advisor) / Tasevska, Natasha (Committee member) / Levinson, Simin (Committee member) / Arizona State University (Publisher)
Created2015
153465-Thumbnail Image.png
Description
ABSTRACT

Asthma is a high-stress, chronic medical condition; 1 in 12 adults in the United States combat the bronchoconstriction from asthma. However, there are very few strong studies indicating any alternative therapy for asthmatics, particularly following a cold incidence. Vitamin C has been proven to be effective for other high-stress

ABSTRACT

Asthma is a high-stress, chronic medical condition; 1 in 12 adults in the United States combat the bronchoconstriction from asthma. However, there are very few strong studies indicating any alternative therapy for asthmatics, particularly following a cold incidence. Vitamin C has been proven to be effective for other high-stress populations, but the asthmatic population has not yet been trialed. This study examined the effectiveness of vitamin C supplementation during the cold season on cold incidence and asthmatic symptoms. Asthmatics, otherwise-healthy, who were non-smokers and non-athletes between the ages of 18 and 55 with low plasma vitamin C concentrations were separated by anthropometrics and vitamin C status into two groups: either vitamin C (500 mg vitamin C capsule consumed twice per day) or control (placebo capsule consumed twice per day). Subjects were instructed to complete the Wisconsin Upper Respiratory Symptom Survey-21 and a short asthma symptoms questionnaire daily along with a shortened vitamin C Food Frequency Questionnaire and physical activity questionnaire weekly for eight weeks. Blood samples were drawn at Week 0 (baseline), Week 4, and Week 8. Compliance was monitored through a calendar check sheet. The vitamin C levels of both groups increased from Week 0 to Week 4, but decreased in the vitamin C group at Week 8. The vitamin C group had a 19% decrease in plasma histamine while the control group had a 53% increase in plasma histamine at the end of the trial, but this was not statistically significant (p>0.05). Total symptoms recorded from WURSS-21 were 129.3±120.7 for the vitamin C and 271.0±293.9, but the difference was not statistically significant (p=0.724). Total asthma symptoms also slightly varied between the groups, but again was not statistically significant (p=0.154). These results were hindered by the low number of subjects recruited. Continued research in this study approach is necessary to definitively reject or accept the potential role of vitamin C in asthma and cold care.
ContributorsEarhart, Kathryn Michelle (Author) / Johnston, Carol (Thesis advisor) / Sweazea, Karen (Committee member) / Lespron, Christy (Committee member) / Arizona State University (Publisher)
Created2015
153326-Thumbnail Image.png
Description
An increase in the number of inverter-interfaced photovoltaic (PV) generators on existing distribution feeders affects the design, operation, and control of the distri- bution systems. Existing distribution system analysis tools are capable of supporting only snapshot and quasi-static analyses. Capturing the dynamic effects of the PV generators during the variation

An increase in the number of inverter-interfaced photovoltaic (PV) generators on existing distribution feeders affects the design, operation, and control of the distri- bution systems. Existing distribution system analysis tools are capable of supporting only snapshot and quasi-static analyses. Capturing the dynamic effects of the PV generators during the variation in the distribution system states is necessary when studying the effects of controller bandwidths, multiple voltage correction devices, and anti-islanding. This work explores the use of dynamic phasors and differential algebraic equations (DAE) for impact analysis of the PV generators on the existing distribution feeders.

The voltage unbalance induced by PV generators can aggravate the existing unbalance due to load mismatch. An increased phase unbalance significantly adds to the neutral currents, excessive neutral to ground voltages and violate the standards for unbalance factor. The objective of this study is to analyze and quantify the impacts of unbalanced PV installations on a distribution feeder. Additionally, a power electronic converter solution is proposed to mitigate the identified impacts and validate the solution's effectiveness through detailed simulations in OpenDSS.

The benefits associated with the use of energy storage systems for electric- utility-related applications are also studied. This research provides a generalized framework for strategic deployment of a lithium-ion based energy storage system to increase their benefits in a distribution feeder. A significant amount of work has been performed for a detailed characterization of the life cycle costs of an energy storage system. The objectives include - reduction of the substation transformer losses, reduction of the life cycle cost for an energy storage system, and accommodate the PV variability.

The distribution feeder laterals in the distribution feeder with relatively high PV generation as compared to the load can be operated as microgrids to achieve reliability, power quality and economic benefits. However, the renewable resources are intermittent and stochastic in nature. A novel approach for sizing and scheduling the energy storage system and microtrubine is proposed for reliable operation of microgrids. The size and schedule of the energy storage system and microturbine are determined using Benders' decomposition, considering the PV generation as a stochastic resource.
ContributorsNagarajan, Adarsh (Author) / Ayyanar, Raja (Thesis advisor) / Vittal, Vijay (Committee member) / Heydt, Gerald (Committee member) / Karady, George G. (Committee member) / Arizona State University (Publisher)
Created2015
153122-Thumbnail Image.png
Description
The subject of this thesis is distribution level load management using a pricing signal in a smart grid infrastructure. The project relates to energy management in a spe-cialized distribution system known as the Future Renewable Electric Energy Delivery and Management (FREEDM) system. Energy management through demand response is one of

The subject of this thesis is distribution level load management using a pricing signal in a smart grid infrastructure. The project relates to energy management in a spe-cialized distribution system known as the Future Renewable Electric Energy Delivery and Management (FREEDM) system. Energy management through demand response is one of the key applications of smart grid. Demand response today is envisioned as a method in which the price could be communicated to the consumers and they may shift their loads from high price periods to the low price periods. The development and deployment of the FREEDM system necessitates controls of energy and power at the point of end use.

In this thesis, the main objective is to develop the control model of the Energy Management System (EMS). The energy and power management in the FREEDM system is digitally controlled therefore all signals containing system states are discrete. The EMS is modeled as a discrete closed loop transfer function in the z-domain. A breakdown of power and energy control devices such as EMS components may result in energy con-sumption error. This leads to one of the main focuses of the thesis which is to identify and study component failures of the designed control system. Moreover, H-infinity ro-bust control method is applied to ensure effectiveness of the control architecture. A focus of the study is cyber security attack, specifically bad data detection in price. Test cases are used to illustrate the performance of the EMS control design, the effect of failure modes and the application of robust control technique.

The EMS was represented by a linear z-domain model. The transfer function be-tween the pricing signal and the demand response was designed and used as a test bed. EMS potential failure modes were identified and studied. Three bad data detection meth-odologies were implemented and a voting policy was used to declare bad data. The run-ning mean and standard deviation analysis method proves to be the best method to detect bad data. An H-infinity robust control technique was applied for the first time to design discrete EMS controller for the FREEDM system.
ContributorsMusani, Aatif (Author) / Heydt, Gerald (Thesis advisor) / Ayyanar, Raja (Committee member) / Holbert, Keith E. (Committee member) / Arizona State University (Publisher)
Created2014