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Accumulating evidence implicates exposure to adverse childhood experiences in the development of hypocortisolism in the long-term, and researchers are increasingly examining individual-level mechanisms that may underlie, exacerbate or attenuate this relation among at-risk populations. The current study takes a developmentally and theoretically informed approach to examining episodic childhood stressors, inherent

Accumulating evidence implicates exposure to adverse childhood experiences in the development of hypocortisolism in the long-term, and researchers are increasingly examining individual-level mechanisms that may underlie, exacerbate or attenuate this relation among at-risk populations. The current study takes a developmentally and theoretically informed approach to examining episodic childhood stressors, inherent and voluntary self-regulation, and physiological reactivity among a longitudinal sample of youth who experienced parental divorce. Participants were drawn from a larger randomized controlled trial of a preventive intervention for children of divorce between the ages of 9 and 12. The current sample included 159 young adults (mean age = 25.5 years; 53% male; 94% Caucasian) who participated in six waves of data collection, including a 15-year follow-up study. Participants reported on exposure to negative life events (four times over a 9-month period) during childhood, and mothers rated child temperament. Six years later, youth reported on the use of active and avoidant coping strategies, and 15 years later, they participated in a standardized psychosocial stress task and provided salivary cortisol samples prior to and following the task. Path analyses within a structural equation framework revealed that a multiple mediation model best fit the data. It was found that children with better mother-rated self-regulation (i.e. low impulsivity, low negative emotionality, and high attentional focus) exhibited lower total cortisol output 15 years later. In addition, greater self-regulation in childhood predicted greater use of active coping in adolescence, whereas a greater number of negative life events predicted increased use of avoidant coping in adolescence. Finally, a greater number of negative events in childhood predicted marginally lower total cortisol output, and higher levels of active coping in adolescence were associated with greater total cortisol output in young adulthood. Findings suggest that children of divorce who exhibit better self-regulation evidence lower cortisol output during a standardized psychosocial stress task relative to those who have higher impulsivity, lower attentional focus, and/or higher negative emotionality. The conceptual significance of the current findings, including the lack of evidence for hypothesized relations, methodological issues that arose, and issues in need of future research are discussed.
ContributorsHagan, Melissa (Author) / Luecken, Linda (Thesis advisor) / MacKinnon, David (Committee member) / Wolchik, Sharlene (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires maintaining tight metabolic control through complex behavioral and pharmaceutical regimens. Subtle cognitive impairments and stress response dysregulation may partially account for problems negotiating life changes and maintaining treatment adherence among emerging adults. The current study examined whether young adults

Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires maintaining tight metabolic control through complex behavioral and pharmaceutical regimens. Subtle cognitive impairments and stress response dysregulation may partially account for problems negotiating life changes and maintaining treatment adherence among emerging adults. The current study examined whether young adults with T1DM physiologically respond to psychological stress in a dysregulated manner compared to non-diabetic peers, and if such individuals also demonstrated greater cognitive declines following psychological stress. Participants included 23 young adults with T1DM and 52 non-diabetic controls yoked to T1DM participants based on age, gender, ethnicity, participant education, and maternal education. Participants completed a laboratory-based social stressor, pre- and post-stressor neurocognitive testing, provided fingerstick blood spots (for glucose levels) and salivary samples (for cortisol levels) at five points across the protocol, and completed psychosocial questionnaires. Related measures ANOVAs were conducted to assess differences between T1DM participants and the average of yoked controls on cortisol and cognitive outcomes. Results demonstrated that differences in cortisol reactivity were dependent on T1DM participants' use of insulin pump therapy (IPT). T1DM participants not using IPT demonstrated elevated cortisol reactivity compared to matched controls. There was no difference in cortisol reactivity between the T1DM participants on IPT and matched controls. On the Stroop task, performance patterns did not differ between participants with T1DM not on IPT and matched controls. The performance of participants with T1DM on IPT slightly improved following the stressor and matched controls slightly worsened. On the Trail Making Test, the performance of participants with T1DM was not different following the stressor whereas participants without T1DM demonstrated a decline following the stressor. Participants with and without T1DM did not differ in patterns of performance on the Rey Verbal Learning Task, Sustained Attention Allocation Task, Controlled Oral Word Association Task, or overall cortisol output across participation. The results of this study are suggestive of an exaggerated cortisol response to psychological stress in T1DM and indicate potential direct and indirect protective influences of IPT.
ContributorsMarreiro, Catherine (Author) / Luecken, Linda (Thesis advisor) / Doane, Leah (Thesis advisor) / Barrera, Manuel (Committee member) / Aiken, Leona (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Although social learning and attachment theories suggest that parent-adolescent relationships influence adult romantic relationships, research on this topic is limited. Most research examining relations between mother-adolescent and father-adolescent relationship quality and young adult romantic relationship quality has found significant effects of mother-adolescent relationship quality. Findings on fathers have been less

Although social learning and attachment theories suggest that parent-adolescent relationships influence adult romantic relationships, research on this topic is limited. Most research examining relations between mother-adolescent and father-adolescent relationship quality and young adult romantic relationship quality has found significant effects of mother-adolescent relationship quality. Findings on fathers have been less consistent. These relations have not been examined among youth who experienced parental divorce, which often negatively impacts parent-child relationships and romantic outcomes. Further, no prior studies examined interactive effects of mother-adolescent and father-adolescent relationship quality on romantic attachment. The current study used longitudinal data from the control group of a randomized controlled trial of a preventative intervention for divorced families to examine unique and interactive effects of mother-adolescent and father-adolescent relationship quality on young adult romantic attachment. The 72 participants completed measures of mother-adolescent relationship quality and father-adolescent relationship quality during adolescence (ages 15-19), and completed a measure of romantic attachment (anxiety and avoidance) during young adulthood (ages 24-28). Findings revealed significant interactive effects of mother-adolescent and father-adolescent relationship quality on young adult romantic anxiety. The pattern of results suggests that having a high quality relationship with one's father can protect children from negative effects of having a low quality relationship with one's mother on romantic anxiety. These results suggest the importance of examining effects of one parent-adolescent relationship on YA romantic attachment in the context of the other parent-adolescent relationship. Exploratory analyses of gender revealed that father-adolescent relationship quality significantly interacted with gender to predict romantic avoidance; this relation was stronger for males. These results suggest that nonresidential fathers play an important role in adolescents' working models of relationships and their subsequent romantic attachment.
ContributorsCarr, Colleen (Author) / Wolchik, Sharlene A (Thesis advisor) / Doane, Leah (Committee member) / Tein, Jenn-Yun (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Research has suggested that lonely people demonstrate distinct differences from nonlonely people in their behaviors, mood, and interpersonal experiences. Lonely people who are also enduring a chronic pain condition may be at an especially high risk for negative outcomes because of simultaneous issues such as stigma, mood disturbances, and pain-related

Research has suggested that lonely people demonstrate distinct differences from nonlonely people in their behaviors, mood, and interpersonal experiences. Lonely people who are also enduring a chronic pain condition may be at an especially high risk for negative outcomes because of simultaneous issues such as stigma, mood disturbances, and pain-related disability. The current study examined chronic and transitory loneliness in a sample of 123 chronic pain patients. Participants completed daily diaries assessing the occurrence of positive and negative interpersonal events, appraisals of interpersonal events, pain, and mood. Multilevel modeling was used to examine effects of being a lonely person as well as having a lonely episode on daily life. Results indicated that both chronic and transitory loneliness were associated with more frequent negative and less frequent positive interpersonal events, higher levels of pain, more negative and less positive affect, and more stress and less enjoyment from social interactions. Loneliness did not affect reactivity to negative interpersonal events, but did influence responsivity to positive interpersonal events such that lonely people had greater boosts in enjoyment when experiencing more positive interpersonal events than usual. These findings suggest that both lonely people and individuals experiencing a lonely episode experience more negative consequences in their daily lives than nonlonely people. However, they can benefit from engaging in more frequent positive interpersonal events, which can help to inform future clinical interventions for lonely, chronic pain patients.
ContributorsDempsey, Laurie (Author) / Davis, Mary (Thesis advisor) / Zautra, Alex (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Current models of pain coping typically focus on how pain contributes to poor physical and psychological functioning. Researchers have argued that this focus on the negative consequences is too narrow and does not account for times when individuals are able to maintain meaningful functioning despite their pain. Thus, the current

Current models of pain coping typically focus on how pain contributes to poor physical and psychological functioning. Researchers have argued that this focus on the negative consequences is too narrow and does not account for times when individuals are able to maintain meaningful functioning despite their pain. Thus, the current study sought to investigate the day-to-day processes that both help and hinder recovery from pain and persistence towards daily goals. Specifically, the present study tested: a) a two-factor model of risk and resilience “factors” that capture key processes across affective, cognitive and social dimensions of functioning, and b) whether the relation between morning pain and end-of-day physical disability is mediated by increases in these afternoon risk and resilience factors. Within-day study measures were collected for 21 days via an automated phone system from 220 participants with Fibromyalgia. The results of multi-level confirmatory factor analysis indicated that, consistent with prediction, risk and resilience do constitute two factors. Findings from multilevel structural equation models also showed resilience factor mediated the link between late morning increases in pain and end-of-day disability, in line with hypotheses. Although the vulnerability factor as a whole did not mediate the within-day link between pain and disability, pain-catastrophizing individually did serve as a significant mediator of this relation. This study was the first to empirically test a within-day latent factor model of resilience and vulnerability and the first to capture the multidimensional nature of the pain experience by examining mechanisms across affective, cognitive and social domains of functioning. The findings of the current study suggest that in addition to studying the processes by which pain has a negative influence on the lives of pain sufferers, our understanding of the pain adaptation process can be further improved by concurrently examining mechanisms that motivate individuals to overcome the urge to avoid pain and to function meaningfully despite it.
ContributorsThummala, Kirti (Author) / Davis, Mary C. (Thesis advisor) / Doane, Leah (Committee member) / Karoly, Paul (Committee member) / Barrera, Manuel (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Adolescent and young adult alcohol use is a major public health concern given that it is the most widely used substance by teenagers. This is particularly concerning given the important biological and environmental changes that occur during this developmental period. Therefore, it is not surprising that alcohol use in adolescence

Adolescent and young adult alcohol use is a major public health concern given that it is the most widely used substance by teenagers. This is particularly concerning given the important biological and environmental changes that occur during this developmental period. Therefore, it is not surprising that alcohol use in adolescence is associated with a variety of negative outcomes including alcohol-related consequences, poor academic performance, aggression, and difficulty transitioning to adulthood. Because of this, it is imperative to better understand alcohol use during this time. While there are numerous measures that aim to capture adolescent alcohol use, there is not currently a measure that gathers comprehensive information on alcohol use across adolescence and into early adulthood. Therefore, we developed the Comprehensive Adolescent Drinking History Form (CADHF). The CADHF gathers detailed drinking information for each year since the onset of first regular use, including quantity and frequency of both regular use and periods of heaviest drinking. Additionally, the CADHF collects information on the participants' aggregate drinking experiences between their age of onset and age of first regular use. Using a sample of young adults who completed an alcohol challenge study, we sought to examine (1) whether route of administration of the measure impacts results, (2) which CADHF are most useful, and (3) whether the CADHF shows concurrent, convergent, and incremental validity. Results showed that, the CADHF can be administered online or over the phone and all eight indices provide valuable information depending on the research question. Additionally, strong significant correlations between the CADHF with the Timeline Follow Back (TLFB) and the Young Adult Alcohol Consequences Questionnaire (YAACQ) suggest convergent and concurrent validity. Finally, the CADHF predicted concurrent and future alcohol-related problems over and above the gold standards of alcohol consumption measures; age of onset, age of first intoxication, and the TLFB. This is the first study to retrospectively assess participant's comprehensive alcohol consumption and fills a major gap in the literature. The CADHF has the potential to inform the timing of prevention and intervention efforts and provides unique information from the current gold standards of alcohol consumption measures.
ContributorsHartman, Jessica (Author) / Corbin, William (Thesis advisor) / Chassin, Laurie (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Guided by the Risky Families model and Daily Process methods, the present study examined how daily stressors are related to emotional well-being at the between- and within-person levels among adolescent grandchildren raised by grandmothers. This study also examined whether risk (i.e., adverse childhood experiences/ACES) and resilience (i.e., socio-emotional skills) factors

Guided by the Risky Families model and Daily Process methods, the present study examined how daily stressors are related to emotional well-being at the between- and within-person levels among adolescent grandchildren raised by grandmothers. This study also examined whether risk (i.e., adverse childhood experiences/ACES) and resilience (i.e., socio-emotional skills) factors were linked to differences in daily well-being, stressor exposure, and emotional reactivity, and evaluated the efficacy of an online social intelligence training (SIT) program on daily stressor-emotion dynamics. Data came from a subsample (n = 188) of custodial adolescents who participated in an attention-controlled randomized clinical trial and completed 14-day daily surveys prior to and following intervention. Analyses were conducted with dynamic structural equation modeling. Daily stressors, on average, and experiencing above average stressors, were associated with higher negative emotions and lower positive emotions and social connection. Those with more ACEs, on average, reported higher daily stressors and worse well-being, whereas those with higher socio-emotional skills, on average, reported lower daily stressors and better well-being. At the within-person level, more ACEs were associated with higher daily negative emotions. Nonverbal processing was linked to higher daily positive emotions and social connection. Conversational skills were associated with higher daily positive emotions and social connection, and lower, more inert daily negative emotions. Neither ACEs nor socio-emotional skills were associated with within-person reactivity to stressors. Also, the SIT program did not demonstrate efficacy for any outcome. My discussion focused on how findings extend the literature on custodial adolescents by showing that daily stressors impact well-being, offer knowledge of how ACEs and socio-emotional skills shape daily stressor-emotion dynamics, and considers reasons why the online, self-guided SIT program failed to show efficacy on key outcomes.
ContributorsCastro, Saul (Author) / Infurna, Frank (Thesis advisor) / Doane, Leah (Committee member) / Davis, Mary (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2023
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Description
An abundance of data has established the links between both pain-related cognitions and relationship attachment qualities in the experience of pain, including long-term functional health in chronic pain patients. However, relatively few studies have explored the dynamic relation between pain and pain-related cognitions within a day, and no studies

An abundance of data has established the links between both pain-related cognitions and relationship attachment qualities in the experience of pain, including long-term functional health in chronic pain patients. However, relatively few studies have explored the dynamic relation between pain and pain-related cognitions within a day, and no studies have tested the moderating role of relationship attachment on the within-day cognition—pain association in chronic pain patients. The objectives of this study were to: 1) assess whether late morning pain flares predicted changes in afternoon positive and negative pain-related cognitive appraisals, and whether these changes in turn predicted end-of-day pain, and 2) explore whether adult attachment anxiety moderated the pain-cognition relation in individuals with chronic pain due to fibromyalgia. One hundred and seventy four partnered individuals with fibromyalgia completed initial assessments of demographics and attachment anxiety, and subsequently completed electronic assessments of pain intensity and positive and negative cognitive pain-related appraisals three times a day for three weeks. Multilevel structural equation modeling established that a latent negative cognitive appraisal factor (encompassing shared variance from catastrophizing, pain irritation, and self-criticism related to pain) mediated the link between late morning and end-of-day pain intensity, in line with the hypothesis. Analyses also provided some support for a mediating role for a positive cognitive appraisal factor (a composite of pain control, pain self-efficacy, and feeling pain without reacting) in the daily course of pain; the mediated effect for positive appraisals was weaker than the mediated effect of negative appraisals, but was sustained in a model that included negative appraisals. Inconsistent with prediction, attachment anxiety did not moderate the within-day links between pain and cognitions. These findings establish the dynamic links within day between pain and pain-related cognitions, and highlight the potential impact of both negative and positive cognitions on daily pain regulation. They point to the value of broadening cognitive-behavioral treatment strategies for chronic pain patients to target not only negative but also positive cognitions.
ContributorsTaylor, Shannon Stark (Author) / Davis, Mary C. (Thesis advisor) / Zautra, Alex (Committee member) / Okun, Morris (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2015
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Interpersonal strain is linked with depressive symptoms in middle-aged adults. Self-compassion is an emerging resilience construct that may be advantageous in navigating relationship strain by helping individuals respond to emotions in a kind and nonjudgmental way. Although theory and empirical evidence suggests that self-compassion is protective against the impact of

Interpersonal strain is linked with depressive symptoms in middle-aged adults. Self-compassion is an emerging resilience construct that may be advantageous in navigating relationship strain by helping individuals respond to emotions in a kind and nonjudgmental way. Although theory and empirical evidence suggests that self-compassion is protective against the impact of stress on mental health outcomes, many studies have not investigated how self-compassion operates in the context of relationship strain. In addition, few studies have examined psychological or physiological mechanisms by which self-compassion protects against mental health outcomes, depression in particular. Thus, this study examined 1) the extent to which trait self-compassion buffers the relation between family strain and depressive symptoms, and 2) whether these buffering effects are mediated by hope and inflammatory processes (IL-6) in a sample of 762 middle-aged, community-dwelling adults. Results from structural equation models indicated that family strain was unrelated to depressive symptoms and the relation was not moderated by self-compassion. Hope, but not IL-6, mediated the relation between family strain and depressive symptoms and the indirect effect was not conditional on levels of self-compassion. Taken together, the findings suggest that family strain may lead individuals to experience less hope and subsequent increases in depressive symptoms, and further, that a self-compassionate attitude does not affect this relation. Implications for future self-compassion interventions are discussed.
ContributorsMistretta, Erin (Author) / Davis, Mary C. (Thesis advisor) / Karoly, Paul (Committee member) / Infurna, Frank (Committee member) / Arizona State University (Publisher)
Created2019
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Stress in individuals presents in various forms and may accumulate across development to predict maladaptive physical and psychological outcomes, including greater risk for the onset of internalizing symptoms. Early life stress, daily life experiences, and the stress response of the hypothalamic-pituitary-adrenal (HPA) axis have all been examined as potential predictors

Stress in individuals presents in various forms and may accumulate across development to predict maladaptive physical and psychological outcomes, including greater risk for the onset of internalizing symptoms. Early life stress, daily life experiences, and the stress response of the hypothalamic-pituitary-adrenal (HPA) axis have all been examined as potential predictors of the development of psychopathology, but rarely have researchers attempted to understand the covariation or interaction among these stress domains using a longitudinal design when looking at the influence of stress on internalizing psychopathology. Further, most research has examined these processes in adulthood or adolescence with much less attention given to the influence of these dynamic stress pathways in childhood. Guided by the biopsychosocial model of stress, this study explored early life stress, daily life stress, diurnal cortisol (cortisol AM slope), and internalizing symptoms in a racially/ethnically and socioeconomically diverse sample of twins participating in an ongoing longitudinal study (N=970 children; Arizona Twin Project; Lemery-Chalfant et al. 2013). An additive model of stress and a stress sensitization framework model were considered as potential pathways of stress to internalizing symptoms in middle childhood. Based on a thorough review of relevant literature, it was expected that each stress indicator would individually predict internalizing symptoms. It was also predicted that early life stress would moderate the associations between diurnal cortisol and internalizing symptoms, as well as daily life stress and internalizing symptoms. Multilevel modeling analyses showed that early life stress and cortisol AM slope, but not daily life stress, predicted internalizing symptoms. Early life stress did not moderate the associations between daily life stress and internalizing symptoms or cortisol AM slope and internalizing symptoms. Results support independent additive contributions of both physiological stress processes and early life parental stressors in the development of internalizing symptoms in middle childhood. Future investigation is needed to better understand the sensitizing effects of early parental life stress during this developmental stage.
ContributorsLecarie, Emma (Author) / Doane, Leah (Thesis advisor) / Davis, Mary (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2020