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- Creators: Arizona State University
- Creators: Goldinger, Stephen D.
Description
ABSTRACT In this work, I provide two novel pieces of evidence in favor of the view that there is pragmatic encroachment on knowledge. First, I present an empirical case via the results of a series of recent experiments to show that folk-knowledge attributions may be sensitive to time constraints even when the latter are construed in a non-truth relevant manner. Along the way, I consider some comments made by Jonathan Schaffer (2006) as it pertains to interpreting time constraints-sensitivity in a manner that supports contextualism, before offering reasons to resist such a treatment. I proceed by applying interest relative invariantism to adjudicate a conflict in the epistemology of testimony namely, the positive reasons requirement a la, reductionism vs. non-reductionism. In particular, I highlight how whether an epistemic subject H needs positive non-testimonial reasons to be justified in accepting S's testimony that p, depends on what is at stake for H in believing that p and how much time H has in deliberating about p.
ContributorsShin, Joseph Ellis (Author) / Pinillos, N. Angel (Thesis advisor) / Reynolds, Steven L (Committee member) / White, Michael J. (Committee member) / Arizona State University (Publisher)
Created2013
Description
Magicians are informal cognitive scientists who regularly test their hypotheses in the real world. As such, they can provide scientists with novel hypotheses for formal psychological research as well as a real-world context in which to study them. One domain where magic can directly inform science is the deployment of attention in time and across modalities. Both magicians and scientists have an incomplete understanding of how attention operates in time, rather than in space. However, magicians have highlighted a set of variables that can create moments of visual attentional suppression, which they call "off-beats," and these variables can speak to modern models of temporal attention. The current research examines two of these variables under conditions ranging from artificial laboratory tasks to the (almost) natural viewing of magic tricks. Across three experiments, I show that the detection of subtle dot probes in a noisy visual display and pieces of sleight of hand in magic tricks can be influenced by the seemingly irrelevant rhythmic qualities of auditory stimuli (cross-modal attentional entrainment) and processes of working memory updating (akin to the attentional blink).
ContributorsBarnhart, Anthony S (Author) / Goldinger, Stephen D. (Thesis advisor) / Glenberg, Arthur M. (Committee member) / Homa, Donald (Committee member) / Simons, Daniel J. (Committee member) / Arizona State University (Publisher)
Created2013
Description
As technology enhances our communication capabilities, the number of distributed teams has risen in both public and private sectors. There is no doubt that these technological advancements have addressed a need for communication and collaboration of distributed teams. However, is all technology useful for effective collaboration? Are some methods (modalities) of communication more conducive than others to effective performance and collaboration of distributed teams? Although previous literature identifies some differences in modalities, there is little research on geographically distributed mobile teams (DMTs) performing a collaborative task. To investigate communication and performance in this context, I developed the GeoCog system. This system is a mobile communications and collaboration platform enabling small, distributed teams of three to participate in a variant of the military-inspired game, "Capture the Flag". Within the task, teams were given one hour to complete as many "captures" as possible while utilizing resources to the advantage of the team. In this experiment, I manipulated the modality of communication across three conditions with text-based messaging only, vocal communication only, and a combination of the two conditions. It was hypothesized that bi-modal communication would yield superior performance compared to either single modality conditions. Results indicated that performance was not affected by modality. Further results, including communication analysis, are discussed within this paper.
ContributorsChampion, Michael (Author) / Cooke, Nancy J. (Thesis advisor) / Shope, Steven (Committee member) / Wu, Bing (Committee member) / Arizona State University (Publisher)
Created2012
Description
Multimodal presentations have been found to facilitate learning, however, may be a disadvantage for low spatial ability students if they require spatial visualization. This disadvantage stems from their limited capacity to spatially visualize and retain information from both text and diagrams for integration. Similarly, working memory capacity (WMC) likely plays a key role in a learner's ability to retain information presented to them via both modalities. The present study investigated whether or not the act of self-explaining helps resolve deficits in learning caused by individual differences in spatial ability, working memory capacity, and prior knowledge when learning with text, or text and diagrams. No interactions were found, but prior knowledge consistently predicted performance on like posttests. The author presents methodological and theoretical explanations as to the null results of the present study.
ContributorsGutierrez, Pedro J (Author) / Craig, Scotty D. (Thesis advisor) / Branaghan, Russell (Committee member) / Sanchez, Cristopher (Committee member) / Arizona State University (Publisher)
Created2014
Description
Following a traumatic brain injury (TBI) 5-50% of patients will develop post traumatic epilepsy (PTE). Pediatric patients are most susceptible with the highest incidence of PTE. Currently, we cannot prevent the development of PTE and knowledge of basic mechanisms are unknown. This has led to several shortcomings to the treatment of PTE, one of which is the use of anticonvulsant medication to the population of TBI patients that are not likely to develop PTE. The complication of identifying the two populations has been hindered by the ability to find a marker to the pathogenesis of PTE. The central hypothesis of this dissertation is that following TBI, the cortex undergoes distinct cellular and synaptic reorganization that facilitates cortical excitability and promotes seizure development. Chapter 2 of this dissertation details excitatory and inhibitory changes in the rat cortex after severe TBI. This dissertation aims to identify cortical changes to a single cell level after severe TBI using whole cell patch clamp and electroencephalogram electrophysiology. The work of this dissertation concluded that excitatory and inhibitory synaptic activity in cortical controlled impact (CCI) animals showed the development of distinct burst discharges that were not present in control animals. The results suggest that CCI induces early "silent" seizures that are detectable on EEG and correlate with changes to the synaptic excitability in the cortex. The synaptic changes and development of burst discharges may play an important role in synchronizing the network and promoting the development of PTE.
ContributorsNichols, Joshua (Author) / Anderson, Trent (Thesis advisor) / Neisewander, Janet (Thesis advisor) / Newbern, Jason (Committee member) / Arizona State University (Publisher)
Created2014
Description
Smoking remains the leading cause of preventable death in the United States, and early initiation is associated with greater difficulty quitting. Among adolescent smokers, those with attention-deficit hyperactivity disorder (ADHD), characterized by difficulties associated with impulsivity, hyperactivity, and inattention, smoke at nearly twice the rate of their peers. Although cigarette smoking is highly addictive, nicotine is a relatively weak primary reinforcer, spurring research on other potential targets that may maintain smoking, including the potential benefits of nicotine on attention, inhibition, and reinforcer efficacy. The present study employs the most prevalent rodent model of ADHD, the spontaneously hypertensive rat (SHR) and its control comparison Wistar Kyoto (WKY) to examine the effects of acute and chronic subcutaneous nicotine injections on performance in three operant response inhibition paradigms. Functional activation in select regions of the prefrontal cortex and striatum was also explored. Acute (0.1, 0.3, 0.6 mg/kg) and chronic (0.3 mg/kg) nicotine increased impulsive responding regardless of strain, dose, or operant schedule. Dose-dependent decreases in latency to initiate the task were also observed. SHR receiving daily nicotine injections showed less activation in the nucleus accumbens shell compared to saline controls. Despite close similarities, one of the three operant tasks did not detect response inhibition deficits in SHR relative to WKY. A closer examination of these tasks may highlight critical components involved in the amelioration of response inhibition deficits.
ContributorsMazur, Gabriel Joseph (Author) / Sanabria, Federico (Thesis advisor) / Killeen, Peter R (Committee member) / Neisewander, Janet L (Committee member) / Wynne, Clive DL (Committee member) / Arizona State University (Publisher)
Created2014
Description
The failure to withhold inappropriate behavior is a central component of most impulse control disorders, including Attention Deficit Hyperactivity Disorder (ADHD). The present study examined the effects of housing environment and methylphenidate (a drug often prescribed for ADHD) on the performance of rats in two response inhibition tasks: differential reinforcement of low rate (DRL) and fixed minimum interval (FMI). Both tasks required rats to wait a fixed amount of time (6 s) before emitting a reinforced response. The capacity to withhold the target response (volitional inhibition) and timing precision were estimated on the basis of performance in each of the tasks. Paradoxically, rats housed in a mildly enriched environment that included a conspecific displayed less volitional inhibition in both tasks compared to rats housed in an isolated environment. Enriched housing, however, increased timing precision. Acute administration of methylphenidate partially reversed the effects of enriched housing. Implications of these results in the assessment and treatment of ADHD-related impulsivity are discussed.
ContributorsHill, Jade C (Author) / Sanabria, Federico (Thesis advisor) / Killeen, Peter (Committee member) / Neisewander, Janet (Committee member) / Arizona State University (Publisher)
Created2011
Description
This research examines the effects of using similar vs. dissimilar models in health messages on message compliance. I find that level of self-awareness moderates the effect of model similarity on message compliance. Across three studies, I demonstrate that when self-awareness is high, a health message that contains a similar model leads to higher compliance than the same message containing a dissimilar model. On the other hand, when self-awareness is low, a health message that contains a similar model leads to lower message compliance than the same message containing a dissimilar model. Additionally, I demonstrate that the increased compliance observed when self-awareness is high and a similar model is used is associated with self-enhancing behavior and increased engagement with the ad, while the decreased compliance observed when self-awareness is low and a similar model is used is associated with disregarding the ad.
ContributorsLoveland, Katherine (Author) / Mandel, Naomi (Thesis advisor) / Miller, Elizabeth G. (Committee member) / Morales, Andrea C. (Committee member) / Smeesters, Dirk (Committee member) / Arizona State University (Publisher)
Created2011
Description
The present study explores the role of motion in the perception of form from dynamic occlusion, employing color to help isolate the contributions of both visual pathways. Although the cells that respond to color cues in the environment usually feed into the ventral stream, humans can perceive motion based on chromatic cues. The current study was designed to use grey, green, and red stimuli to successively limit the amount of information available to the dorsal stream pathway, while providing roughly equal information to the ventral system. Twenty-one participants identified shapes that were presented in grey, green, and red and were defined by dynamic occlusion. The shapes were then presented again in a static condition where the maximum occlusions were presented as before, but without motion. Results showed an interaction between the motion and static conditions in that when the speed of presentation increased, performance in the motion conditions became significantly less accurate than in the static conditions. The grey and green motion conditions crossed static performance at the same point, whereas the red motion condition crossed at a much slower speed. These data are consistent with a model of neural processing in which the main visual systems share information. Moreover, they support the notion that presenting stimuli in specific colors may help isolate perceptual pathways for scientific investigation. Given the potential for chromatic cues to target specific visual systems in the performance of dynamic object recognition, exploring these perceptual parameters may help our understanding of human visual processing.
ContributorsHolloway, Steven R. (Author) / McBeath, Michael K. (Thesis advisor) / Homa, Donald (Committee member) / Macknik, Stephen L. (Committee member) / Arizona State University (Publisher)
Created2011
Description
Dopamine (DA) is a neurotransmitter involved in attention, goal oriented behavior, movement, reward learning, and short term and working memory. For the past four decades, mathematical and computational modeling approaches have been useful in DA research, and although every modeling approach has limitations, a model is an efficient way to generate and explore hypotheses. This work develops a model of DA dynamics in a representative, single DA neuron by integrating previous experimental, theoretical and computational research. The model consists of three compartments: the cytosol, the vesicles, and the extracellular space and forms the basis of a new mathematical paradigm for examining the dynamics of DA synthesis, storage, release and reuptake. The model can be driven by action potentials generated by any model of excitable membrane potential or even from experimentally induced depolarization voltage recordings. Here the model is forced by a previously published model of the excitable membrane of a mesencephalic DA neuron in order to study the biochemical processes involved in extracellular DA production. After demonstrating that the model exhibits realistic dynamics resembling those observed experimentally, the model is used to examine the functional changes in presynaptic mechanisms due to application of cocaine. Sensitivity analysis and numerical studies that focus on various possible mechanisms for the inhibition of DAT by cocaine provide insight for the complex interactions involved in DA dynamics. In particular, comparing numerical results for a mixed inhibition mechanism to those for competitive, non-competitive and uncompetitive inhibition mechanisms reveals many behavioral similarities for these different types of inhibition that depend on inhibition parameters and levels of cocaine. Placing experimental results within this context of mixed inhibition provides a possible explanation for the conflicting views of uptake inhibition mechanisms found in experimental neuroscience literature.
ContributorsTello-Bravo, David (Author) / Crook, Sharon M (Thesis advisor) / Greenwood, Priscilla E (Thesis advisor) / Baer, Steven M. (Committee member) / Castaneda, Edward (Committee member) / Castillo-Chavez, Carlos (Committee member) / Arizona State University (Publisher)
Created2012