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Due to depletion of oil resources, increasing fuel prices and environmental issues associated with burning of fossil fuels, extensive research has been performed in biofuel production and dramatic progress has been made. But still problems exist in economically production of biofuels. One major problem is recovery of biofuels from fermentation broth with the relatively low product titer achieved. A lot of in situ product recovery techniques including liquid-liquid extraction, membrane extraction, pervaporation, gas stripping and adsorption have been developed and adsorption is shown to be the most promising one compared to other methods. Yet adsorption is not perfect due to defect in adsorbents and operation method used. So laurate adsorption using polymer resins was first investigated by doing adsorption isotherm, kinetic, breakthrough curve experiment and column adsorption of laurate from culture. The results indicate that polymer resins have good capacity for laurate with the highest capacity of 430 g/kg achieved by IRA-402 and can successfully recover laurate from culture without causing problem to Synechocystis sp.. Another research of this paper focused on a novel adsorbent: magnetic particles by doing adsorption equilibrium, kinetic and toxicity experiment. Preliminary results showed excellent performance on both adsorption capacity and kinetics. But further experiment revealed that magnetic particles were toxicity and inhibited growth of all kinds of cell tested severely, toxicity probably comes from Co (III) in magnetic particles. This problem might be solved by either using biocompatible coatings or immobilization of cells, which needs more investigation.
ContributorsWang, Yuchen (Author) / Nielsen, David Ross (Thesis advisor) / Andino, Jean (Committee member) / Torres, Cesar (Committee member) / Arizona State University (Publisher)
Created2012
Description
Hematopoietic stem cell transplantation (HSCT) is a unique but intense procedure used to save the lives of patients with hematopoietic malignancies. However, patients and caregivers undergoing HSCT can experience prolonged psychological distress due to an intense and distinctive transplant process. Types of psychological distress include anxiety, depression, social isolation, and post-traumatic stress disorder. Although this a significant healthcare problem, limited research has been conducted within the HSCT patient and caregiver population to investigate ways to improve their mental health. The purpose of this study was to examine the effects of an educational video intervention about post-transplant recovery in decreasing emotional distress and promoting emotional well-being in HSCT patients and caregivers. This pilot study utilized a quantitative single-group pretest-posttest design to examine the effect of educational videos on participant's emotional well-being. Four educational videos were developed using information gathered from several reliable bone marrow transplant and cancer websites. A convenience sampling method was used to recruit HSCT patient and caregiver participants. Eleven Caucasian, English-speaking individuals (6 patients, 5 caregivers; 54.5% female; M age= 43.7 years) across the United States were enrolled in the 60-90 minute online intervention. Participant responses were measured using pretest and posttest questionnaires. Results from the study found that the educational videos were effective in decreasing levels of depression and anxiety. Implications for nursing practice include the need to educate HSCT patients and caregivers about transplant recovery to decrease emotional distress. This study demonstrates the impact post-transplant education has on decreasing depression and anxiety in HSCT patients and caregivers.
ContributorsBosselman, Kate Elizabeth (Author) / Kim, Sunny (Thesis director) / Lee, Rebecca (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12