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Sex trafficking is an issue that is prevalent in the United States, including in Arizona. The Catholic Charities Diversion Program in Phoenix seeks to rehabilitate adults who have been involved in prostitution. The aim of this paper was to test three pilot interventions to address stress experienced by the program

Sex trafficking is an issue that is prevalent in the United States, including in Arizona. The Catholic Charities Diversion Program in Phoenix seeks to rehabilitate adults who have been involved in prostitution. The aim of this paper was to test three pilot interventions to address stress experienced by the program clients through three different techniques that were given in workshop format. Cognitive Behavior Therapy (CBT), Dance Movement Therapy, and yoga and meditation are the three types of stress reduction techniques that have been studied in previous research and were pilot tested with adult sex trafficking victims. The results of the pilot studies and all three techniques reduced levels of stress significantly, and they warrant future testing.
ContributorsSatapathy, Nikita (Co-author) / Khanal, Garima (Co-author) / Somayaji, Vallari (Co-author) / Roe-Sepowitz, Dominique (Thesis director) / Graff, Sarah (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Almost every form of cancer deregulates the expression and activity of anabolic glycosyltransferase (GT) enzymes, which incorporate particular monosaccharides in a donor acceptor as well as linkage- and anomer-specific manner to assemble complex and diverse glycans that significantly affect numerous cellular events, including tumorigenesis and metastasis. Because glycosylation is not

Almost every form of cancer deregulates the expression and activity of anabolic glycosyltransferase (GT) enzymes, which incorporate particular monosaccharides in a donor acceptor as well as linkage- and anomer-specific manner to assemble complex and diverse glycans that significantly affect numerous cellular events, including tumorigenesis and metastasis. Because glycosylation is not template-driven, GT deregulation yields heterogeneous arrays of aberrant intact glycan products, some in undetectable quantities in clinical bio-fluids (e.g., blood plasma). Numerous glycan features (e.g., 6 sialylation, β-1,6-branching, and core fucosylation) stem from approximately 25 glycan “nodes:” unique linkage specific monosaccharides at particular glycan branch points that collectively confer distinguishing features upon glycan products. For each node, changes in normalized abundance (Figure 1) may serve as nearly 1:1 surrogate measure of activity for culpable GTs and may correlate with particular stages of carcinogenesis. Complementary to traditional top down glycomics, the novel bottom-up technique applied herein condenses each glycan node and feature into a single analytical signal, quantified by two GC-MS instruments: GCT (time-of-flight analyzer) and GCMSD (transmission quadrupole analyzers). Bottom-up analysis of stage 3 and 4 breast cancer cases revealed better overall precision for GCMSD yet comparable clinical performance of both GC MS instruments and identified two downregulated glycan nodes as excellent breast cancer biomarker candidates: t-Gal and 4,6-GlcNAc (ROC AUC ≈ 0.80, p < 0.05). Resulting from the activity of multiple GTs, t-Gal had the highest ROC AUC (0.88) and lowest ROC p‑value (0.001) among all analyzed nodes. Representing core-fucosylation, glycan node 4,6-GlcNAc is a nearly 1:1 molecular surrogate for the activity of α-(1,6)-fucosyltransferase—a potential target for cancer therapy. To validate these results, future projects can analyze larger sample sets, find correlations between breast cancer stage and changes in t-Gal and 4,6-GlcNAc levels, gauge the specificity of these nodes for breast cancer and their potential role in other cancer types, and develop clinical tests for reliable breast cancer diagnosis and treatment monitoring based on t-Gal and 4,6-GlcNAc.
ContributorsZaare, Sahba (Author) / Borges, Chad (Thesis director) / LaBaer, Joshua (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Establishing a healthcare practice in the U. S. by a Mexican national involves many different steps at federal as well as state levels. The recent implementation of the Patient Protection and Affordable Care Act overhauls some requirements which include increased Medicaid eligibility as well as mandatory health insurance coverage. With

Establishing a healthcare practice in the U. S. by a Mexican national involves many different steps at federal as well as state levels. The recent implementation of the Patient Protection and Affordable Care Act overhauls some requirements which include increased Medicaid eligibility as well as mandatory health insurance coverage. With these changes taking place over the next few years, the need for healthcare providers will expand. Consequently, I look into the requirements of establishing an urgent care practice in the state of Arizona. Given that Phoenix has a 40.8% Hispanic population and that the Affordable Care Act will increase the coverage of this demographic, it is the city of focus for my analysis. In order to make access to the Arizona healthcare market more impartial and accessible to Mexican entrepreneurs, changes need to be made to the certification process of medical physicians who graduated from Mexican universities. The general disadvantage of Mexican physicians as compared to their U. S. counterparts comes in the form of increased certification times and additional processes. An equal playing field will allow the ease in movement of medical physicians between the U. S. and Mexico which will help meet the increased demand over the next few years. From ownership to taxation and medical billing and coding, this analysis focuses on the many requirements needed to establish an urgent care in Arizona.
ContributorsIbarra, Joseph Anthony (Author) / Carlos, Velez-Ibanez (Thesis director) / Cruz-Torres, Maria (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor)
Created2014-05
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Description
In December of 2015, I made my way to rural Peru for a few weeks, my first visit to South America. While I was there, I observed a devotion to family and leisure activity, topics that were not heavily prioritized in my experience in Arizona. Upon my return, I became

In December of 2015, I made my way to rural Peru for a few weeks, my first visit to South America. While I was there, I observed a devotion to family and leisure activity, topics that were not heavily prioritized in my experience in Arizona. Upon my return, I became more involved in leisure activities, particularly running, hiking, yoga, and climbing. These involvements noticeably benefitted my health and well-being. The way the Peruvians I met prioritized these subjects fascinated me, and I wanted to study this difference between Arizona and Peru. In July of 2017, I returned to Peru for a semester abroad with my bags packed and the following research questions: 1) Are differences in motivation for rock climbing between Arizona and Peruvian climbers associated with cultural values? 2) Do leisure activities and the amount of time spent on them have an effect on quality of life? 3) Does the degree of climbing specialization impact perceptions of well-being? 4) What characteristics impact perceptions of quality of life among climbers? Are these characteristics affected by country of origin? My prediction was that Peruvians had higher quality of life due to their emphasis on leisure. Through this study, I learned that this conclusion was not as simple as I anticipated.
ContributorsMatta, Samantha Tania (Author) / Hultsman, Wendy (Thesis director) / Sampson, David (Committee member) / Lee, Rebecca (Committee member) / College of Integrative Sciences and Arts (Contributor) / School of Molecular Sciences (Contributor) / Division of Teacher Preparation (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
The growing Hispanic population in Phoenix, Arizona frequently lacks financial resources which may limit their access to health care. The goal of this study was to identify the ideal factors in a health insurance plan for the Hispanic/Latino population in Phoenix, AZ. A survey was designed to gather information regarding

The growing Hispanic population in Phoenix, Arizona frequently lacks financial resources which may limit their access to health care. The goal of this study was to identify the ideal factors in a health insurance plan for the Hispanic/Latino population in Phoenix, AZ. A survey was designed to gather information regarding demographics, health insurance, preferences, and affordability. The survey was completed by 260 participants. Several multivariate regressions were run using SAS Statistical Software. The final model generated explained 4.48% of the variation in the data set. It showed that an individual who identified as Hispanic/Latino was 8.2% less likely to have health insurance. In addition, an individual who identified as a US Citizen was 23% more likely to have health insurance. To improve access and enrollment among the Hispanic/Latino population, further investigation is needed to identify relevant communication techniques that increase enrollment among this high-risk community.
ContributorsToo, Rachel Yun-May (Author) / Whisner, Corrie (Thesis director) / Calvin, Samantha (Committee member) / Cook, Aaron (Committee member) / Economics Program in CLAS (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
More than 90 million Americans suffer from low health literacy levels that can lead to detrimental health practices. One of the greatest issues stemming from low health literacy is the misuse of medication, which results in 125,000 deaths per year and close to $200 billion dollars in health care funds

More than 90 million Americans suffer from low health literacy levels that can lead to detrimental health practices. One of the greatest issues stemming from low health literacy is the misuse of medication, which results in 125,000 deaths per year and close to $200 billion dollars in health care funds (Ngoh 2009). With their implementation into neighborhood settings and consequently the everyday lives of individuals, pharmacies show potential in being great assets towards increasing health literacy on an individual and societal level. However, pharmacists must first be made aware of the opportunities and challenges that exist concerning this effort. Through a three step literature review and corresponding comparative analysis, the results of this study show that pharmacists should focus on four main areas: overall assessment of health literacy in a pharmacy setting, individualization and tailoring of health/ medication plans, development of verbal and written communication tools, and the pharmacist-patient relationship. Each area presents a set of opportunities and challenges that must be accounted for in order to design more effective initiatives and tools in the pharmacists' aim to increase health literacy.
ContributorsMergens, Rianna Lynn (Author) / Robert, Jason Scott (Thesis director) / Maienschein, Jane (Committee member) / Kinzig, Ann (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2013-05
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Description
Planned Parenthood, one of the United States' largest providers of reproductive health services, has campaigned for decades to secure women's reproductive rights in the political sphere. However, few scholars have written on the social and political history that preceded the general religious and Republican hostility toward the organization in the

Planned Parenthood, one of the United States' largest providers of reproductive health services, has campaigned for decades to secure women's reproductive rights in the political sphere. However, few scholars have written on the social and political history that preceded the general religious and Republican hostility toward the organization in the twenty-first century. Through Planned Parenthood's growth in the mid-twentieth century, both political parties and many religious organizations pushed for family planning and access to contraception as solutions to population growth and poverty. Arizona was used as a case study to examine the broader context of the shift in the ideas of political parties and religious organizations surrounding the reproductive rights movement from the start of the twentieth century until the 1980s. The historical trajectory of the shifting religious and political support for Planned Parenthood Arizona was demonstrated using both a literature review and archival research. Throughout the early 1900s, Republicans advocated for limited governmental intrusion into citizens' lives, which extended to women's reproduction, where contraception was seen as a private decision between a woman and her doctor. That changed in the late twentieth century when religious concerns exacerbated the political discussion following the legalization of abortion in 1973 and the appointment of Ronald Regan in 1981, one of the first outspoken pro-life presidents. Planned Parenthood faced increasing criticism from religious organizations and the Republican Party. The social and political history surrounding Planned Parenthood Arizona illustrates the interplay between politics and the reproductive rights movement throughout the twentieth century. The contextualization of major historical events during the development of Planned Parenthood Arizona gives insight into the current political and religious beliefs regarding the reproductive rights movement.
ContributorsNunez-Eddy, Claudia Margarita (Author) / Maienschein, Jane (Thesis director) / O'Neil, Erica (Committee member) / Abboud, Alexis (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational changes to combat the SARS-CoV-2 pandemic. At ASU, information technology was one of the six facets identified in the ongoing review of the ASU Biodesign Clinical Testing Laboratory (ABCTL) among business, communications, management/training, law, and clinical analysis. The first chapter of this manuscript covers the background of clinical laboratory automation and details the automated laboratory workflow to perform ABCTL’s COVID-19 diagnostic testing. The second chapter discusses the usability and efficiency of key information technology systems of the ABCTL. The third chapter explains the role of quality control and data management within ABCTL’s use of information technology. The fourth chapter highlights the importance of data modeling and 10 best practices when responding to future public health emergencies.

ContributorsWoo, Sabrina (Co-author) / Leung, Michael (Co-author) / Kandan, Mani (Co-author) / Knox, Garrett (Co-author) / Compton, Carolyn (Thesis director) / Dudley, Sean (Committee member) / School of Life Sciences (Contributor) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational changes to combat the SARS-CoV-2 pandemic. At ASU, information technology was one of the six facets identified in the ongoing review of the ASU Biodesign Clinical Testing Laboratory (ABCTL) among business, communications, management/training, law, and clinical analysis. The first chapter of this manuscript covers the background of clinical laboratory automation and details the automated laboratory workflow to perform ABCTL’s COVID-19 diagnostic testing. The second chapter discusses the usability and efficiency of key information technology systems of the ABCTL. The third chapter explains the role of quality control and data management within ABCTL’s use of information technology. The fourth chapter highlights the importance of data modeling and 10 best practices when responding to future public health emergencies.

ContributorsLeung, Michael (Co-author) / Kandan, Mani (Co-author) / Knox, Garrett (Co-author) / Woo, Sabrina (Co-author) / Compton, Carolyn (Thesis director) / Dudley, Sean (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

The history of Arizona is filled with ambitious pioneers, courageous Natives, and loyal<br/>soldiers, but there is a seeming disconnect between those who came before us and many of those<br/>who currently inhabit this space. Many historic locations that are vital to discovering the past in<br/>Arizona are both hard to find and

The history of Arizona is filled with ambitious pioneers, courageous Natives, and loyal<br/>soldiers, but there is a seeming disconnect between those who came before us and many of those<br/>who currently inhabit this space. Many historic locations that are vital to discovering the past in<br/>Arizona are both hard to find and lacking in information pertaining to what happened there.<br/>However, despite the apparent lack of history and knowledge pertaining to these locations, they<br/>are vitally present in the public memory of the region, and we wish to shed some much-needed<br/>light on a few of these locations and the historical takeaways that can be gleaned from their<br/>study. This thesis argues the significance of three concepts: place-making, public memory, and<br/>stories. Place-making is the reinvention of history in the theater of mind which creates a<br/>plausible reality of the past through what is known in the present. Public memory is a way to<br/>explain how events in a location affect the public consciousness regarding that site and further<br/>events that stem from it. Lastly, stories about a place and event help to explain its overall impact<br/>and what can be learned from the occurrences there. Throughout this thesis we will be discussing<br/>seven sites across Arizona, the events that occurred there, and how these three aspects of study<br/>can be used to experience history in a personal way that gives us a special perspective on the<br/>land around us. The importance of personalizing history lies in finding our own identity as<br/>inhabitants of this land we call home and knowing the stories gives us greater attachment to the<br/>larger narrative of humanity as it has existed in this space.

ContributorsMartin, Trevor James (Co-author) / Martin, Austin (Co-author) / Fixico, Donald (Thesis director) / O'Donnell, Catherine (Committee member) / Dean, W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05