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Description
Widespread adoption of smartphone based Mobile Medical Apps (MMAs) is opening new avenues for innovation, bringing MMAs to the forefront of low cost healthcare delivery. These apps often control human physiology and work on sensitive data. Thus it is necessary to have evidences of their trustworthiness i.e. maintaining privacy of

Widespread adoption of smartphone based Mobile Medical Apps (MMAs) is opening new avenues for innovation, bringing MMAs to the forefront of low cost healthcare delivery. These apps often control human physiology and work on sensitive data. Thus it is necessary to have evidences of their trustworthiness i.e. maintaining privacy of health data, long term operation of wearable sensors and ensuring no harm to the user before actual marketing. Traditionally, clinical studies are used to validate the trustworthiness of medical systems. However, they can take long time and could potentially harm the user. Such evidences can be generated using simulations and mathematical analysis. These methods involve estimating the MMA interactions with human physiology. However, the nonlinear nature of human physiology makes the estimation challenging.

This research analyzes and develops MMA software while considering its interactions with human physiology to assure trustworthiness. A novel app development methodology is used to objectively evaluate trustworthiness of a MMA by generating evidences using automatic techniques. It involves developing the Health-Dev β tool to generate a) evidences of trustworthiness of MMAs and b) requirements assured code generation for vulnerable components of the MMA without hindering the app development process. In this method, all requests from MMAs pass through a trustworthy entity, Trustworthy Data Manager which checks if the app request satisfies the MMA requirements. This method is intended to expedite the design to marketing process of MMAs. The objectives of this research is to develop models, tools and theory for evidence generation and can be divided into the following themes:

• Sustainable design configuration estimation of MMAs: Developing an optimization framework which can generate sustainable and safe sensor configuration while considering interactions of the MMA with the environment.

• Evidence generation using simulation and formal methods: Developing models and tools to verify safety properties of the MMA design to ensure no harm to the human physiology.

• Automatic code generation for MMAs: Investigating methods for automatically

• Performance analysis of trustworthy data manager: Evaluating response time generating trustworthy software for vulnerable components of a MMA and evidences.performance of trustworthy data manager under interactions from non-MMA smartphone apps.
ContributorsBagade, Priyanka (Author) / Gupta, Sandeep K. S. (Thesis advisor) / Wu, Carole-Jean (Committee member) / Doupe, Adam (Committee member) / Zhang, Yi (Committee member) / Arizona State University (Publisher)
Created2015
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Description
The availability of a wide range of general purpose as well as accelerator cores on

modern smartphones means that a significant number of applications can be executed

on a smartphone simultaneously, resulting in an ever increasing demand on the memory

subsystem. While the increased computation capability is intended for improving

user experience, memory requests

The availability of a wide range of general purpose as well as accelerator cores on

modern smartphones means that a significant number of applications can be executed

on a smartphone simultaneously, resulting in an ever increasing demand on the memory

subsystem. While the increased computation capability is intended for improving

user experience, memory requests from each concurrent application exhibit unique

memory access patterns as well as specific timing constraints. If not considered, this

could lead to significant memory contention and result in lowered user experience.

This work first analyzes the impact of memory degradation caused by the interference

at the memory system for a broad range of commonly-used smartphone applications.

The real system characterization results show that smartphone applications,

such as web browsing and media playback, suffer significant performance degradation.

This is caused by shared resource contention at the application processor’s last-level

cache, the communication fabric, and the main memory.

Based on the detailed characterization results, rest of this thesis focuses on the

design of an effective memory interference mitigation technique. Since web browsing,

being one of the most commonly-used smartphone applications and represents many

html-based smartphone applications, my thesis focuses on meeting the performance

requirement of a web browser on a smartphone in the presence of background processes

and co-scheduled applications. My thesis proposes a light-weight user space frequency

governor to mitigate the degradation caused by interfering applications, by predicting

the performance and power consumption of web browsing. The governor selects an

optimal energy-efficient frequency setting periodically by using the statically-trained

performance and power models with dynamically-varying architecture and system

conditions, such as the memory access intensity of background processes and/or coscheduled applications, and temperature of cores. The governor has been extensively evaluated on a Nexus 5 smartphone over a diverse range of mobile workloads. By

operating at the most energy-efficient frequency setting in the presence of interference,

energy efficiency is improved by as much as 35% and with an average of 18% compared

to the existing interactive governor, while maintaining the satisfactory performance

of web page loading under 3 seconds.
ContributorsShingari, Davesh (Author) / Wu, Carole-Jean (Thesis advisor) / Vrudhula, Sarma (Committee member) / Shrivastava, Aviral (Committee member) / Arizona State University (Publisher)
Created2016
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Description
A benchmark suite that is representative of the programs a processor typically executes is necessary to understand a processor's performance or energy consumption characteristics. The first contribution of this work addresses this need for mobile platforms with MobileBench, a selection of representative smartphone applications. In smartphones, like any other

A benchmark suite that is representative of the programs a processor typically executes is necessary to understand a processor's performance or energy consumption characteristics. The first contribution of this work addresses this need for mobile platforms with MobileBench, a selection of representative smartphone applications. In smartphones, like any other portable computing systems, energy is a limited resource. Based on the energy characterization of a commercial widely-used smartphone, application cores are found to consume a significant part of the total energy consumption of the device. With this insight, the subsequent part of this thesis focuses on the portion of energy that is spent to move data from the memory system to the application core's internal registers. The primary motivation for this work comes from the relatively higher power consumption associated with a data movement instruction compared to that of an arithmetic instruction. The data movement energy cost is worsened esp. in a System on Chip (SoC) because the amount of data received and exchanged in a SoC based smartphone increases at an explosive rate. A detailed investigation is performed to quantify the impact of data movement

on the overall energy consumption of a smartphone device. To aid this study, microbenchmarks that generate desired data movement patterns between different levels of the memory hierarchy are designed. Energy costs of data movement are then computed by measuring the instantaneous power consumption of the device when the micro benchmarks are executed. This work makes an extensive use of hardware performance counters to validate the memory access behavior of microbenchmarks and to characterize the energy consumed in moving data. Finally, the calculated energy costs of data movement are used to characterize the portion of energy that MobileBench applications spend in moving data. The results of this study show that a significant 35% of the total device energy is spent in data movement alone. Energy is an increasingly important criteria in the context of designing architectures for future smartphones and this thesis offers insights into data movement energy consumption.
ContributorsPandiyan, Dhinakaran (Author) / Wu, Carole-Jean (Thesis advisor) / Shrivastava, Aviral (Committee member) / Lee, Yann-Hang (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Abnormally low or high blood iron levels are common health conditions worldwide and can seriously affect an individual’s overall well-being. A low-cost point-of-care technology that measures blood iron markers with a goal of both preventing and treating iron-related disorders represents a significant advancement in medical care delivery systems. Methods: A

Abnormally low or high blood iron levels are common health conditions worldwide and can seriously affect an individual’s overall well-being. A low-cost point-of-care technology that measures blood iron markers with a goal of both preventing and treating iron-related disorders represents a significant advancement in medical care delivery systems. Methods: A novel assay equipped with an accurate, storable, and robust dry sensor strip, as well as a smartphone mount and (iPhone) app is used to measure total iron in human serum. The sensor strip has a vertical flow design and is based on an optimized chemical reaction. The reaction strips iron ions from blood-transport proteins, reduces Fe(III) to Fe(II), and chelates Fe(II) with ferene, with the change indicated by a blue color on the strip. The smartphone mount is robust and controls the light source of the color reading App, which is calibrated to obtain output iron concentration results. The real serum samples are then used to assess iron concentrations from the new assay and validated through intra-laboratory and inter-laboratory experiments. The intra-laboratory validation uses an optimized iron detection assay with multi-well plate spectrophotometry. The inter-laboratory validation method is performed in a commercial testing facility (LabCorp). Results: The novel assay with the dry sensor strip and smartphone mount, and App is seen to be sensitive to iron detection with a dynamic range of 50 - 300 µg/dL, sensitivity of 0.00049 µg/dL, coefficient of variation (CV) of 10.5%, and an estimated detection limit of ~15 µg/dL These analytical specifications are useful for predicting iron deficiency and overloads. The optimized reference method has a sensitivity of 0.00093 µg/dL and CV of 2.2%. The correlation of serum iron concentrations (N=20) between the optimized reference method and the novel assay renders a slope of 0.95, and a regression coefficient of 0.98, suggesting that the new assay is accurate. Lastly, a spectrophotometric study of the iron detection reaction kinetics is seen to reveal the reaction order for iron and chelating agent. Conclusion: The new assay is able to provide accurate results in intra- and inter- laboratory validations and has promising features of both mobility and low-cost.
ContributorsSerhan, Michael (Author) / Forzani, Erica (Thesis advisor) / Raupp, Gregory (Committee member) / Acharya, Abhinav (Committee member) / Hu, Tony (Committee member) / Smith, Barbara (Committee member) / Arizona State University (Publisher)
Created2020
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Description
While various collision warning studies in driving have been conducted, only a handful of studies have investigated the effectiveness of warnings with a distracted driver. Across four experiments, the present study aimed to understand the apparent gap in the literature of distracted drivers and warning effectiveness, specifically by studying various

While various collision warning studies in driving have been conducted, only a handful of studies have investigated the effectiveness of warnings with a distracted driver. Across four experiments, the present study aimed to understand the apparent gap in the literature of distracted drivers and warning effectiveness, specifically by studying various warnings presented to drivers while they were operating a smart phone. Experiment One attempted to understand which smart phone tasks, (text vs image) or (self-paced vs other-paced) are the most distracting to a driver. Experiment Two compared the effectiveness of different smartphone based applications (app’s) for mitigating driver distraction. Experiment Three investigated the effects of informative auditory and tactile warnings which were designed to convey directional information to a distracted driver (moving towards or away). Lastly, Experiment Four extended the research into the area of autonomous driving by investigating the effectiveness of different auditory take-over request signals. Novel to both Experiment Three and Four was that the warnings were delivered from the source of the distraction (i.e., by either the sound triggered at the smart phone location or through a vibration given on the wrist of the hand holding the smart phone). This warning placement was an attempt to break the driver’s attentional focus on their smart phone and understand how to best re-orient the driver in order to improve the driver’s situational awareness (SA). The overall goal was to explore these novel methods of improved SA so drivers may more quickly and appropriately respond to a critical event.
ContributorsMcNabb, Jaimie Christine (Author) / Gray, Dr. Rob (Thesis advisor) / Branaghan, Dr. Russell (Committee member) / Becker, Dr. Vaughn (Committee member) / Arizona State University (Publisher)
Created2017