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Description
HIV/AIDS is the sixth leading cause of death worldwide and the leading cause of death among women of reproductive age living in low-income countries. Clinicians in industrialized nations monitor the efficacy of antiretroviral drugs and HIV disease progression with the HIV-1 viral load assay, which measures the copy number of

HIV/AIDS is the sixth leading cause of death worldwide and the leading cause of death among women of reproductive age living in low-income countries. Clinicians in industrialized nations monitor the efficacy of antiretroviral drugs and HIV disease progression with the HIV-1 viral load assay, which measures the copy number of HIV-1 RNA in blood. However, viral load assays are not widely available in sub-Saharan Africa and cost between 50-$139 USD per test on average where available. To address this problem, a mixed-methods approach was undertaken to design a novel and inexpensive viral load diagnostic for HIV-1 and to evaluate barriers to its adoption in a developing country. The assay was produced based on loop-mediated isothermal amplification (LAMP). Blood samples from twenty-one individuals were spiked with varying concentrations of HIV-1 RNA to evaluate the sensitivity and specificity of LAMP. Under isothermal conditions, LAMP was performed with an initial reverse-transcription step (RT-LAMP) and primers designed for HIV-1 subtype C. Each reaction generated up to a few billion copies of target DNA within an hour. Presence of target was detected through naked-eye observation of a fluorescent indicator and verified by DNA gel electrophoresis and real-time fluorescence. The assay successfully detected the presence of HIV in samples with a broad range of HIV RNA concentration, from over 120,000 copies/reaction to 120 copies/reaction. In order to better understand barriers to adoption of LAMP in developing countries, a feasibility study was undertaken in Tanzania, a low-income country facing significant problems in healthcare. Medical professionals in Northern Tanzania were surveyed for feedback regarding perspectives of current HIV assays, patient treatment strategies, availability of treatment, treatment priorities, HIV transmission, and barriers to adoption of the HIV-1 LAMP assay. The majority of medical providers surveyed indicated that the proposed LAMP assay is too expensive for their patient populations. Significant gender differences were observed in response to some survey questions. Female medical providers were more likely to cite stigma as a source problem of the HIV epidemic than male medical providers while males were more likely to cite lack of education as a source problem than female medical providers.
ContributorsSalamone, Damien Thomas (Author) / Jacobs, Bertram L (Thesis advisor) / Marsiglia, Flavio (Committee member) / Stout, Valerie (Committee member) / Johnson, Crista (Committee member) / Arizona State University (Publisher)
Created2011
Description
The current study sought to reevaluate Cass' Theory of sexual identity formation in terms of lesbian identity development over the past twenty years and how media acts as mediation in lesbian identity development. Ten semi-structured interviews were conducted with only nine useable transcripts analyzed for this thesis. This study is

The current study sought to reevaluate Cass' Theory of sexual identity formation in terms of lesbian identity development over the past twenty years and how media acts as mediation in lesbian identity development. Ten semi-structured interviews were conducted with only nine useable transcripts analyzed for this thesis. This study is an explanatory investigation into linear stage theory, specifically Cass' theory, as well as the impact of media as a mediator during lesbian identity development. This study had three objectives 1) to gain an understanding of the theory and its components related to lesbian identity development 2) to understand the lesbian identity formation process and 3) to understand the impact and influence if any, media has had on lesbian self-reported identity development. Qualitative methods were used to obtain information and analyze the responses. Results indicate that the participants in this study believed that the coming out process was important. This study's results showed that several of the participants entered each stage of the theory, while others did not. Media had little influence on the identity development, and the participants had mixed reviews of medias portrayal of lesbians. Implications for practice and further research are discussed.
ContributorsHaseley, Hilary (Author) / Lacasse, Jeffrey R (Thesis advisor) / Segal, Elizabeth (Committee member) / Rounds, Tamara (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Communication skills within dating contexts are developed during the adolescent years, and are associated with a lifelong ability to have satisfying, enduring, and non-violent partnerships. As such, they are currently and increasingly implemented into both more general forms of healthy relationship education, as well as that targeting the prevention of

Communication skills within dating contexts are developed during the adolescent years, and are associated with a lifelong ability to have satisfying, enduring, and non-violent partnerships. As such, they are currently and increasingly implemented into both more general forms of healthy relationship education, as well as that targeting the prevention of teen dating violence specifically. Reaching Mexican American youth with culturally and developmentally appropriate relationship education, including communication skills, may be particularly important given their earlier transitions to marital and parenting relationships, acculturative stressors that present them with unique coupling challenges, and their higher rates of teen dating violence as compared to European American youth. We know very little about how Mexican American dating couples communicate about areas of conflict. This dissertation research utilizes Bell and Naugle's (2008) framework of interpersonal violence to explore how cultural and developmental considerations may be integrated in order to better understand how communication behaviors contribute to Mexican American middle adolescents' experiences with dating conflict. I use an observational study design in order to 1.) Qualitatively explore the communication strategies used by a sample of committed couples, including integration of culturally- and developmentally-relevant contexts, 2.) Quantitatively examine whether couple-level discrepancies in acculturation are associated with observed negativity, including whether this relationship may be mediated by dissimilar gender-related beliefs, and to 3.) Review empirical findings pertaining to the communication behaviors of Mexican American adolescents and to integrate ecodevelopmental theory in said framework as informed by Papers 1, 2, and literature specific to this topic area. The ultimate aim of this dissertation research is to generate findings that may improve the dating health of Mexican American adolescents living in the United States.
ContributorsAdams, Heidi (Author) / Rankin Williams, Lela (Thesis advisor) / Marsiglia, Flavio (Committee member) / Anthony, Elizabeth (Committee member) / Arizona State University (Publisher)
Created2013
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Description
This study aimed to fill the gap in research with regards to how individuals who define themselves as LGBT (lesbian, gay, bisexual, and transgendered) and devoutly religious (either currently or in the past) manage the interaction between these two conflicting identities. The researchers conducted 8 semi-structured qualitative interviews to examine

This study aimed to fill the gap in research with regards to how individuals who define themselves as LGBT (lesbian, gay, bisexual, and transgendered) and devoutly religious (either currently or in the past) manage the interaction between these two conflicting identities. The researchers conducted 8 semi-structured qualitative interviews to examine how these individuals manage this conflict and what affects these individuals experience internally and externally. To analyze the interviews, researchers used an open coding method to determine the common themes amongst the participants. Results indicated that these participants traveled a similar path when attempting to manage the conflict between their religion and sexuality and similar internal and external affects were experienced amongst the participants.
ContributorsWheeler, Heather (Author) / Gerdes, Karen (Thesis advisor) / Klimek, Barbara (Committee member) / Segal, Elizabeth (Committee member) / Arizona State University (Publisher)
Created2013
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Description
African American students are one of the historically disadvantaged groups by the public education system. Related to this phenomenon is the overrepresentation of African American children in special education due to disability diagnoses, which has been referred to as disproportionality. It has been hypothesized that disproportionality is due to poverty

African American students are one of the historically disadvantaged groups by the public education system. Related to this phenomenon is the overrepresentation of African American children in special education due to disability diagnoses, which has been referred to as disproportionality. It has been hypothesized that disproportionality is due to poverty or a cultural mismatch between primarily white, middle-class teachers and African American students. Using a sample of African American children in special education from Memphis, Tennessee, this secondary data analysis explored the relationship between children's behavioral and educational outcomes and their environment, efficacy beliefs, and the impact of an intervention, the Nurse-Family Partnership. This study also explored differences in children's externalizing and internalizing behaviors by self-report, children's mothers and children's teachers. Using multiple imputation and regression analyses, the results indicated the following: 1) children's self-efficacy and number of hours in special education were associated with children's academic achievement, 2) mothers' and teachers' ratings of children's behaviors differed from children's self-report of their behaviors, 3) African American boys are more likely to experience acting-out behaviors, while African American girls are more likely to experience anxiety and depression, 4) children were less likely to experience anxiety and depression if their mother believed that she had control over circumstances in her life. These findings are discussed in light of Brofenbrenner's ecological systems theory and Bandura's social cognitive theory.
ContributorsBean, Kristen (Author) / Segal, Elizabeth (Thesis advisor) / Arcoleo, Kimberly (Committee member) / Gerdes, Karen (Committee member) / Arizona State University (Publisher)
Created2012
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Description
ABSTRACT The relationships between adaptive and maladaptive aspects of gender roles in predicting substance use were examined in a sample of 955 (450 boys, 505 girls) Mexican American 7th and 8th grade adolescents participating in a school-based substance use intervention. The moderating effect of linguistic acculturation, the mediating effects of

ABSTRACT The relationships between adaptive and maladaptive aspects of gender roles in predicting substance use were examined in a sample of 955 (450 boys, 505 girls) Mexican American 7th and 8th grade adolescents participating in a school-based substance use intervention. The moderating effect of linguistic acculturation, the mediating effects of antisociality, depressive symptoms, and adaptive and avoidant coping on gender role-substance use relationships were examined. Correlational and path analyses supported the Functional Model of Gender Roles that considers these roles as adaptive or maladaptive social coping strategies. For boys, the path analyses yielded significant direct paths from aggressive masculinity to composite alcohol, cigarette, and marijuana use measures, with all other effects of gender roles on substance use operating through the mediators. Bootstrapped mediation tests yielded significant indirect paths, where for boys the positive relationships between assertive and aggressive masculinity with substance use and the negative relationship of affective femininity with substance use were mediated through antisociality, which is predictive of increased substance use. For girls, the positive relationship between aggressive masculinity with cigarette and alcohol use and the negative relationship of affective femininity with alcohol and cigarette use were also mediated by adaptive coping, which is predictive of decreased substance use. A different set of significant indirect paths through avoidant coping connected assertive masculinity and submissive femininity to alcohol use for boys. For boys, the paths from affective femininity to antisociality and adaptive coping were found to be moderated by linguistic acculturation, with the negative correlation of affective femininity with antisociality and positive correlation of this gender role with adaptive coping being stronger in boys low in acculturation. In turn, the pathway from this acculturation by affective femininity interaction to substance use was found to be mediated by antisociality. The present analyses confirmed the importance of gender roles and their interaction with acculturation in predicting substance use in Mexican American adolescents. The analyses also were important in delineating functional mechanisms through which these gender roles have their effects, with implications for the design of interventions to reduce substance use in this population.
ContributorsNagoshi, Julieann Lynn (Author) / Kulis, Stephen (Thesis advisor) / Marsiglia, Flavio (Committee member) / Gillmore, Mary (Committee member) / Arizona State University (Publisher)
Created2012
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Description
A child’s death evokes intense and long-lasting grief in parents. However, few interventions exist to address the needs of this population. This mixed methods project used secondary data to evaluate the impact of a four-day, grief-focused mindfulness-based retreat on bereaved parents.

A quasi-experimental design with two nonequivalent groups (intervention grou

A child’s death evokes intense and long-lasting grief in parents. However, few interventions exist to address the needs of this population. This mixed methods project used secondary data to evaluate the impact of a four-day, grief-focused mindfulness-based retreat on bereaved parents.

A quasi-experimental design with two nonequivalent groups (intervention group n = 25, comparison group n = 41) and three observations (pretest and two posttests) was used. Mixed-model repeated-measures analyses of variance were used to assess change over time for the intervention group and relative to a no-intervention comparison group. Outcome measures were depressive and anxious responses, measured by the Hopkins Symptom Checklist-25 (HSCL-25); trauma responses, measured by the Impact of Event Scale-Revised (IES-R); mindfulness, measured by the Five Facet Mindfulness Questionnaire (FFMQ); and self-compassion, measured by the Self-Compassion Scale-Short Form (SCS-SF). The intervention group was expected to show significant decreases in psychological distress and significant increases in mindfulness and self-compassion over time and relative to the comparison group.

The qualitative component consisted of semi-structured interviews with nineteen retreat participants using a constructivist phenomenological approach in order to obtain a richer understanding of the retreat’s impact on participants’ lives.

There were significant time by condition interactions with small to medium effect sizes for the IES-R and its subscales, the HSCL-25 and its depression subscale, and three FFMQ scales (describe, act with awareness, and nonjudge), all favoring the intervention group. However, not all benefits were maintained at follow-up.

Psychoeducation and relationships emerged as key qualitative themes. Psychoeducation included benefits related to present-moment awareness, fully inhabiting grief, self-compassion, emotional equanimity, and reduced distress or judgment of distress. Relationships included benefits related to giving and receiving social support, emotional expression and sharing, validation and normalization of grief-related experiences, resonance and self-other awareness, self-appraisal, changes in relationships, and connection to a deceased child. Mindfulness seemed to be a key component in reducing trauma responses. Relationship factors, combined with psychoeducation and present-moment awareness, seemed responsible for increasing participants’ capacity for nonjudgmental acceptance of experiences.

The retreat may be an effective intervention for helping parents cope with and express their grief and warrants further study.
ContributorsThieleman, Kara (Author) / Cacciatore, Joanne (Thesis advisor) / Segal, Elizabeth (Committee member) / Hodge, David (Committee member) / Arizona State University (Publisher)
Created2019
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Description
All ethnic groups in the U.S. have suffered from elder maltreatment (EM), but literature on this topic among Chinese Americans is sparse. Only one group of researchers has exclusively focused on the EM experiences of Chinese Americans in the U.S. A recent study indicated the prevalence rate of EM was

All ethnic groups in the U.S. have suffered from elder maltreatment (EM), but literature on this topic among Chinese Americans is sparse. Only one group of researchers has exclusively focused on the EM experiences of Chinese Americans in the U.S. A recent study indicated the prevalence rate of EM was 24% among residential-dwelling Chinese American elders and the most prevalent forms of EM are psychological maltreatment (10%) and financial maltreatment (10%). However, the effect of family relationship and cultural factors on EM have not yet been explored. The traditional Chinese culture emphasizing family cohesion and filial piety, along with the acculturation stress and language barriers may increase the risks of EM in this population.

This exploratory research aimed to understand EM perpetrated by family members in residential settings among Chinese American elders and the risk factors of EM in this population, focusing on the Phoenix metropolitan area. Particularly, understanding EM through both a cultural lens and a legal lens shed light on the roles of socio-cultural variables (family support and cultural variables) associated with EM among Chinese American elders, one of the fastest growing ethnic groups in the U.S.

To achieve these research aims, a larger quantitative component building on a small qualitative component was utilized. In Phase I, focus groups were conducted to ensure subsequent survey questions were culturally and linguistically appropriate. Feedback from the focus groups was used to refine the questionnaire designed for this study. In Phase II, revised questionnaires were distributed to 266 Chinese American older adults to detect EM prevalence and to identify the factors associated with victimization. The ecological theory provides guidance for the study.

In the end, one of ten Chinese American elders experienced general EM perpetrated by family members. The dominant forms of EM, elder neglect and emotional maltreatment, may have serious emotional outcomes and threaten the well-being of Chinese elders. To prevent the occurrence and recurrence of EM, service professionals and gatekeepers in the community need to work with Chinese American families to reduce elders’ depression levels, promote family cohesion and eliminate the intergenerational culture/acculturation differences.
ContributorsGao, Xiang, Ph.D (Author) / Sun, Fei (Thesis advisor) / Bonifas, Robin (Committee member) / Marsiglia, Flavio (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Using integrated threat theory as the theoretical framework, this study examines the impact of perceived realistic threats (threats to welfare) and symbolic threats (threats to worldview) on anti-immigrant sentiment among a nationally representative sample in the U.S. Analysis of the antecedents of prejudice is particularly relevant today as anti-immigrant sentiment

Using integrated threat theory as the theoretical framework, this study examines the impact of perceived realistic threats (threats to welfare) and symbolic threats (threats to worldview) on anti-immigrant sentiment among a nationally representative sample in the U.S. Analysis of the antecedents of prejudice is particularly relevant today as anti-immigrant sentiment and hostile policies toward the population have risen in the past two decades. Perceived discrimination has also become salient within immigrant communities, negatively impacting both mental and physical health. Using logistic ordinal regressions with realistic threat, symbolic threat, and immigrant sentiment scales, this study found that both realistic and symbolic threats increased participants' likelihood of selecting a higher level of anti-immigrant sentiment, suggesting both are predictive of prejudice. However, symbolic threats emerged as a greater predictor of anti-immigrant sentiment, with an effect size over twice that of realistic threats. Implications for social work policy, practice, and future research are made.
ContributorsKiehne, Elizabeth (Author) / Becerra, David (Thesis advisor) / Segal, Elizabeth (Committee member) / Androff, David K. (Committee member) / Arizona State University (Publisher)
Created2014
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Description
The Arizona legislature has enacted a number of anti-immigrant policies which negatively impact Latino immigrant families. The purpose of this study was to explore the perceptions of Latino parents on how anti-immigration policies emotionally impact their children and how they believe they can protect their children from the harmful effects

The Arizona legislature has enacted a number of anti-immigrant policies which negatively impact Latino immigrant families. The purpose of this study was to explore the perceptions of Latino parents on how anti-immigration policies emotionally impact their children and how they believe they can protect their children from the harmful effects of such policies. Secondary data analysis was conducted based on in-depth semi structured interviews completed with a sample of 54 Latino immigrant parents residing in the state of Arizona. Grounded theory methods informed the analysis process. A constant comparative approach was used to complete initial and focused coding. Findings indicate that Latino immigrant parents observed a range of behavioral changes in their children following the passage of anti-immigrant legislature. Parents reported that the emotional impact they observed stemmed from children's social interactions in their home, school, and community environments as well as through their exposure to the media. Latino youth experienced emotional impact is summarized in the following themes, concern and sense of responsibility; fear and hypervigilance; sadness and crying; and depression. Findings further demonstrated that parents protected Latino youth from anti-immigration policies directly and indirect ways by focusing on children's safety and well-being (let children live their childhood, be prepared, send messages), building parents capacity (pursue education, obtain papers), and engaging in change efforts at the community level (be proactive). Parents indicated that by engaging in these efforts they could protect their children, and counter the negative effects of anti-immigrant policies. Implications for social work practice to better advocate and serve Latino youth at the individual, family, and community level are discussed.
ContributorsRubio-Hernandez, Sandy (Author) / Ayón, Cecilia (Thesis advisor) / Bacallao, Martica (Committee member) / Segal, Elizabeth (Committee member) / Arizona State University (Publisher)
Created2015