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Description
Military veterans have a significantly higher incidence of mild traumatic brain injury (mTBI), depression, and Post-traumatic stress disorder (PTSD) compared to civilians. Military veterans also represent a rapidly growing subgroup of college students, due in part to the robust and financially incentivizing educational benefits under the Post-9/11 GI Bill. The

Military veterans have a significantly higher incidence of mild traumatic brain injury (mTBI), depression, and Post-traumatic stress disorder (PTSD) compared to civilians. Military veterans also represent a rapidly growing subgroup of college students, due in part to the robust and financially incentivizing educational benefits under the Post-9/11 GI Bill. The overlapping cognitively impacting symptoms of service-related conditions combined with the underreporting of mTBI and psychiatric-related conditions, make accurate assessment of cognitive performance in military veterans challenging. Recent research findings provide conflicting information on cognitive performance patterns in military veterans. The purpose of this study was to determine whether service-related conditions and self-assessments predict performance on complex working memory and executive function tasks for military veteran college students. Sixty-one military veteran college students attending classes at Arizona State University campuses completed clinical neuropsychological tasks and experimental working memory and executive function tasks. The results revealed that a history of mTBI significantly predicted poorer performance in the areas of verbal working memory and decision-making. Depression significantly predicted poorer performance in executive function related to serial updating. In contrast, the commonly used clinical neuropsychological tasks were not sensitive service-related conditions including mTBI, PTSD, and depression. The differing performance patterns observed between the clinical tasks and the more complex experimental tasks support that researchers and clinicians should use tests that sufficiently tax verbal working memory and executive function when evaluating the subtle, higher-order cognitive deficits associated with mTBI and depression.
ContributorsGallagher, Karen Louise (Author) / Azuma, Tamiko (Thesis advisor) / Liss, Julie (Committee member) / Lavoie, Michael (Committee member) / Arizona State University (Publisher)
Created2017
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Description
This study examines the one month retention of executive function benefits gained by adolescents with Down syndrome after an 8-week aerobic exercise intervention. Sixteen participants were randomly divided between voluntary (VC) (i.e., self-selected cadence) and assisted (AC) (i.e., 30% faster than self-selected cadence accomplished by a motor) cycling groups, with

This study examines the one month retention of executive function benefits gained by adolescents with Down syndrome after an 8-week aerobic exercise intervention. Sixteen participants were randomly divided between voluntary (VC) (i.e., self-selected cadence) and assisted (AC) (i.e., 30% faster than self-selected cadence accomplished by a motor) cycling groups, with one participant used as a control (NC). Both cycling groups rode a stationary bicycle, for 30 minutes, three times a week, for eight weeks. At the beginning (i.e., pretest) and end (posttest) of the 8-week session, three executive functions including: set-switching, inhibition, and cognitive planning, were tested. Approximately one month after the posttest, all participants underwent the cognitive testing again. The results showed that for the AC group cognitive planning improved after eight weeks of assisted cycling and these improvements were maintained after one month of no cycling. However, no significant differences were found between the cycling groups for our measure of inhibition. Set-switching appeared to be improved by both types of exercise, rather than only assisted, but the improvements were not maintained during the one month retention period for either group. Thus, our results suggest that Assisted Cycling causes potentially permanent changes in the brain in regards to cognitive planning.
ContributorsRichter, Madeline B. (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Maraj, Brian (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Description
Mild TBI (mTBI) has been associated with subtle executive function (EF) and

cognitive-communication deficits. In bilinguals, there are unique cognitive demands required to control and process two languages effectively. Surprisingly, little is known about the impact of mTBI on EF, communication, and language control in bilinguals. Therefore, the aim of this

Mild TBI (mTBI) has been associated with subtle executive function (EF) and

cognitive-communication deficits. In bilinguals, there are unique cognitive demands required to control and process two languages effectively. Surprisingly, little is known about the impact of mTBI on EF, communication, and language control in bilinguals. Therefore, the aim of this study was to examine the cognitive-communication abilities in bilinguals with a history of mTBI, identify any language control impairments, and explore the relationship between these language control impairments and domain-general cognitive control abilities. To this end, three-hundred and twenty-seven monolingual and bilingual college students with and without mTBI history participated in two experiments. In these experiments, EF, communication, and language control were examined using experimental and clinical tasks as well as self-rating scales. In Experiment 1, there was an interaction between mTBI history and language group (monolinguals vs. bilinguals) in how participants performed on a clinical measure of EF and a verbal fluency task. That is, only bilinguals with mTBI scored significantly lower on these tasks. In addition, there was a significant correlation between errors on a language switching task and performance on non-verbal EF tasks. In Experiment 2, a subgroup of bilinguals with persistent cognitive and behavioral symptoms reported greater everyday communication challenges in their first and second languages. Also, unbalanced bilinguals reported greater EF difficulties than monolinguals and balanced bilinguals regardless of mTBI history. In conclusion, bilinguals may face unique cognitive-communication challenges after mTBI. Factors related to the bilingual experience (e.g., language balance, daily language use) should be

considered in clinical evaluation and future research.
ContributorsAlateeq, Halah (Author) / Azuma, Tamiko (Thesis advisor) / Ratiu, Ileana (Committee member) / Lavoie, Michael (Committee member) / Arizona State University (Publisher)
Created2020
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Description
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by difficulties in aspects of executive functioning such as inattention, hyperactivity, and impulsivity (American Psychiatric Association [APA], 2022). These challenges may impact learning and information retrieval, leading to variations in academic, vocational, and social skill development (APA, 2022). Precise assessment of these

Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by difficulties in aspects of executive functioning such as inattention, hyperactivity, and impulsivity (American Psychiatric Association [APA], 2022). These challenges may impact learning and information retrieval, leading to variations in academic, vocational, and social skill development (APA, 2022). Precise assessment of these skills is crucial for understanding the diverse cognitive, behavioral, and emotional challenges associated with an ADHD diagnosis. Despite a global prevalence rate between 5-10%, no standardized assessment method has been established (Neprily et al., 2023). The development of digital tools like the NIH Toolbox Cognition Battery (NTCB) and Test of Variables of Attention (T.O.V.A.) offer enhanced accessibility and efficacy in early detection (Greenberg et al., 2007; Weintraub et al., 2013).The study evaluates select NTCB measures of executive functioning, assessing their convergent and discriminant validity alongside established neuropsychological tests. It also investigates whether the T.O.V.A. and NTCB can identify unique cognitive profiles in an ADHD sample, further evaluating sex- and age-based profile differences. Correlation analyses using SPSS (Version 28) revealed strong convergent and discriminant validity of the NTCB Flanker, Dimensional Change Card Sort, and Pattern Comparison tests, with variable discriminant validity on the List Sorting test. Latent profile analysis (LPA) was used to identify distinct profiles using NTCB and T.O.V.A. tests within a sample of 213 participants between the ages of 5 and 26 years diagnosed with ADHD. Analyses were performed using MPlus8 statistical software, with missing data being accounted for by using full information likelihood estimation (FIML). Model selections were based on the number of fit indices and criteria (Nylund et al., 2013). By adjusting unique combinations of subtests and scores from both measures, 2 to 3 distinct profiles emerged within the data, underscoring the heterogeneity and complexity of this clinical population. The data did not support sex-based performance differences; however, older cohorts demonstrated stronger NTCB working memory and processing speed performances. The results highlight the versatility of the NTCB and T.O.V.A. in identifying unique neurocognitive profiles. Future research should explore their efficacy in diagnosing ADHD within diverse medical and psychiatric cohorts, aligning with emerging neuronal circuit theories.
ContributorsSchaefer, Amber Nicole (Author) / Capielo Rosario, Cristalís (Thesis advisor) / Truong, Nancy (Committee member) / Nicholls, Christopher J (Committee member) / Lavoie, Michael (Committee member) / Arizona State University (Publisher)
Created2023