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Previous research has found improvements in motor and cognitive measures following Assisted Cycle Therapy (AC) in adolescence with Down syndrome (DS). Our study investigated whether we would find improvements in mental health in older adults with DS as measured from the Adapted Behavior Dementia Questionnaire (ABDQ), Physical Activity Self Efficacy

Previous research has found improvements in motor and cognitive measures following Assisted Cycle Therapy (AC) in adolescence with Down syndrome (DS). Our study investigated whether we would find improvements in mental health in older adults with DS as measured from the Adapted Behavior Dementia Questionnaire (ABDQ), Physical Activity Self Efficacy Scales (PACES), Children's Depressive inventory, which are early indicators of Alzheimer's disease (AD) in persons with Down syndrome. This study consisted of seven participants with Down syndrome between the ages of 31 and 54, inclusive, that cycled for 30 minutes 3 x/week for eight weeks either at their voluntary cycling rate (VC) or approximately 35% faster with the help of a mechanical motor (ACT). Our results were consistent with our prediction that self efficacy improved following ACT, but not VC. However, our results were not consistent with our prediction that dementia and depression were improved following ACT more than VC. These results were interpreted with respect to the effects of exercise in older adults with DS. Future research should focus on recruiting more participants, especially those with deficits in mental health.
ContributorsPandya, Sachin (Author) / Ringenbach, Shannon (Thesis director) / Coon, David (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
This study examines cognitive planning in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-three participants were randomly assigned to assisted cycling (AC) (i.e., at least 30% faster than self-selected cadence accomplished by a motor), voluntary cycling (VC) (self-selected cadence), and no cycling (NC) control group.

This study examines cognitive planning in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-three participants were randomly assigned to assisted cycling (AC) (i.e., at least 30% faster than self-selected cadence accomplished by a motor), voluntary cycling (VC) (self-selected cadence), and no cycling (NC) control group. Both AC and VC rode a stationary bicycle three times/week, 30 minutes/session, for eight weeks in duration. Participants completed cognitive testing that assessed cognitive planning at the beginning (i.e., pretest) and end (i.e., posttest) of the 8-week intervention. Consistent with our hypothesis, the results showed that cognitive planning improved following eight weeks of cycling for the AC group. The same results were not seen for individuals in the VC or NC groups. Our results suggest that assisted cycling therapy may induce permanent changes in the prefrontal cortex in adolescents with DS.
ContributorsMillar, Kelsey Leann (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
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Description
The aim of this study is to examine the relationship between Assisted Cycle Therapy, leisure time activity levels, fine motor control, and grip force in older adults with Down syndrome (DS), all of which affect activities of daily living (ADL) and therefore quality of life. This is relevant because this

The aim of this study is to examine the relationship between Assisted Cycle Therapy, leisure time activity levels, fine motor control, and grip force in older adults with Down syndrome (DS), all of which affect activities of daily living (ADL) and therefore quality of life. This is relevant because this particular group is at risk for developing early onset Alzheimer's disease (AD), which presents itself uniquely in this population. The parent or guardian of six participants with DS completed Godin's Leisure Time Exercise Questionnaire and the participants themselves completed Purdue Pegboard and grip force assessments before and after an 8-week exercise intervention. The results were inconsistent with past research, with no change being seen in fine motor control or grip force and a decrease being seen in leisure activity. These findings are indicative of the importance of the effect of fatigue on leisure activity as well as maintaining elevated heart rate throughout exercise interventions.
ContributorsGomez, Elizabeth Danielle (Author) / Ringenbach, Shannon (Thesis director) / Coon, David (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2015-05
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Description
This study examines cognitive and motor function in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-four participants were randomly assigned to three groups consisting of an assisted cycling (AC) (i.e., exercise accomplished through the use of a motor), a voluntary cycling (VC) (self-selected cadence), and

This study examines cognitive and motor function in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-four participants were randomly assigned to three groups consisting of an assisted cycling (AC) (i.e., exercise accomplished through the use of a motor), a voluntary cycling (VC) (self-selected cadence), and a no cycling (NC) control group. Both ACT and VC groups rode a stationary bicycle for three 30-minute sessions a week, for a total of eight weeks. Participants completed cognitive testing that assessed information processing and manual dexterity at the beginning and at the end of the 8-week intervention. Consistent with our hypothesis, the results showed that information processing and manual dexterity improved following 8 weeks of cycling for the ACT group. These results were not seen for individuals in the voluntary and non-exercise groups. Our results suggest that assisted cycling therapy may induce permanent changes in the prefrontal cortex in adolescents with DS.
ContributorsJimenez, Andrew (Author) / Ringenbach, Shannon (Thesis director) / Kulinna, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
Adaptive behavior consists of the social, conceptual and practical skills an individual must execute to function independently in their everyday life. Individuals with Down syndrome have limitations in their adaptive behavior due to cognitive and physical deficits. The aim of this study was to examine if an exercise program would

Adaptive behavior consists of the social, conceptual and practical skills an individual must execute to function independently in their everyday life. Individuals with Down syndrome have limitations in their adaptive behavior due to cognitive and physical deficits. The aim of this study was to examine if an exercise program would improve the adaptive behavior skills in persons with Down syndrome. The exercise intervention, Exercise for Adults with Down Syndrome (ExDS), was a semester long program where adults with Down syndrome participate in twice weekly workouts planned and executed by Arizona State University students. The workouts consisted of an aerobic warm up, aerobic exercises, resistance exercises, balance exercises and stretches. The participants' adaptive behavior and cognitive planning ability were assessed before ExDS and after ExDS. The Adaptive Behavior Assessment System Second Edition (ABAS-II) was used to measure adaptive behavior. The ABAS-II consisted of a forum that addressed the Social, Conceptual and Practical domains of adaptive behavior and was filled out by the participants' caregiver. The Tower of London (ToL) was used to measure cognitive planning ability. The change in the ABAS-II scores from pre- to post-testing were statistically insignificant. The change from pre- to post-testing in the ToL scores approached statistical significance. Limitations included bias caregiver perception and respondent inconsistency. There is a need for further research on the effect of exercise on the adaptive behavior in adults with Down syndrome.
ContributorsRoss, Alexandra Jill (Author) / Holzapfel, Simon (Thesis director) / Ringenbach, Shannon (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Description
This study examines the one month retention of executive function benefits gained by adolescents with Down syndrome after an 8-week aerobic exercise intervention. Sixteen participants were randomly divided between voluntary (VC) (i.e., self-selected cadence) and assisted (AC) (i.e., 30% faster than self-selected cadence accomplished by a motor) cycling groups, with

This study examines the one month retention of executive function benefits gained by adolescents with Down syndrome after an 8-week aerobic exercise intervention. Sixteen participants were randomly divided between voluntary (VC) (i.e., self-selected cadence) and assisted (AC) (i.e., 30% faster than self-selected cadence accomplished by a motor) cycling groups, with one participant used as a control (NC). Both cycling groups rode a stationary bicycle, for 30 minutes, three times a week, for eight weeks. At the beginning (i.e., pretest) and end (posttest) of the 8-week session, three executive functions including: set-switching, inhibition, and cognitive planning, were tested. Approximately one month after the posttest, all participants underwent the cognitive testing again. The results showed that for the AC group cognitive planning improved after eight weeks of assisted cycling and these improvements were maintained after one month of no cycling. However, no significant differences were found between the cycling groups for our measure of inhibition. Set-switching appeared to be improved by both types of exercise, rather than only assisted, but the improvements were not maintained during the one month retention period for either group. Thus, our results suggest that Assisted Cycling causes potentially permanent changes in the brain in regards to cognitive planning.
ContributorsRichter, Madeline B. (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Maraj, Brian (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Description
The aim of this study was to examine the influence of Assisted Cycling Therapy (ACT) on information processing measured by simple reaction time in older adults with Down Syndrome (DS). Twenty-one participants were randomly assigned to one of three interventions over eight weeks. 1) Eleven older adults with Down Syndrome

The aim of this study was to examine the influence of Assisted Cycling Therapy (ACT) on information processing measured by simple reaction time in older adults with Down Syndrome (DS). Twenty-one participants were randomly assigned to one of three interventions over eight weeks. 1) Eleven older adults with Down Syndrome completed the ACT intervention, which is stationary cycling with the assistance of a motor to maintain a cadence at least 35% greater than voluntary cycling. 2) Eight older adults with Down Syndrome completed the voluntary cycling (VC) intervention and 3) two older adults with Down Syndrome were in our no cycling (NC) intervention. Both exercise groups participated in the eight-week, supervised exercise protocol for at least three, 30-minute sessions per week. None of our results reached conventional levels of significance. However, the greatest improvements in reaction time occurred following the voluntary cycling (VC) intervention. Our results are discussed with respect to physiological differences in older adults with DS that may limit improvements in executive function following exercise. These physiological differences and limitations include muscle atrophy and reduced perceptions, age related latency between motor cortex activation and onset of muscle activity, as well as general age related slowing in reaction time. Although it may be difficult to improve executive function in older adults with DS, we suggest other benefits to exercise which include improving social communication, gross motor skills, and exercise perception. Future research should continue to investigate the effects of exercise on multiple areas in older adults with DS with the hopes of improving quality of life.
ContributorsCahill, Colleen Mary (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Lower extremity function is vital for activities of daily living especially in stroke survivors. An innovative way to improve lower extremity function may be Assisted Cycle Therapy. This is among the first studies to examine ACT in stroke survivors. Twenty-three participants post-stroke performed ACT, VC and NC and pre and

Lower extremity function is vital for activities of daily living especially in stroke survivors. An innovative way to improve lower extremity function may be Assisted Cycle Therapy. This is among the first studies to examine ACT in stroke survivors. Twenty-three participants post-stroke performed ACT, VC and NC and pre and post measures of lower extremity function were conducted with the Lower Extremity Motor Coordination Test (LEMOCOT). The results showed that the non-paretic lower extremity improved its function after ACT, but not after VC or NC. Lower extremity function in the paretic leg improved after ACT and VC, but not after NC. These results suggest that ACT resulted in increased production of BDNF in the motor cortex which resulted in improvements in global motor function.
ContributorsSzeto, Monica (Author) / Ringenbach, Shannon (Thesis director) / Holzapfel, Simon (Committee member) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Upper extremity function is vital for activities of daily living especially in stroke survivors. An innovative way to improve upper extremity function has been shown with Assisted Cycle Therapy (ACT). This is among the first study to examine ACT in stroke survivors. 13 stroke survivors performed ACT, VC, and NC

Upper extremity function is vital for activities of daily living especially in stroke survivors. An innovative way to improve upper extremity function has been shown with Assisted Cycle Therapy (ACT). This is among the first study to examine ACT in stroke survivors. 13 stroke survivors performed ACT, VC, and NC and pre and post measures of upper extremity function were conducted with the box and blocks test (BBT). The results showed that non-paretic upper extremity improved its function after ACT and VC, but not after NC. For the paretic arm, while the results did not reach conventional levels of significance, improvements in upper extremity function following ACT more so than VC or NC. These results were interpreted to suggest that ACT resulted in increased production of BDNF in the motor cortex, which resulted in improvements in global motor function.
ContributorsHeyer, Brittany Nicole (Author) / Ringenbach, Shannon (Thesis director) / Holzapfel, Simon (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Executive function is vital for activities of daily living especially in stroke survivors because it is critical to everyday tasks (e.g., driving, cooking, etc.). An innovative way to improve executive function may be Assisted Cycling Therapy (ACT). This is among the first studies to use a Stroop task to measure

Executive function is vital for activities of daily living especially in stroke survivors because it is critical to everyday tasks (e.g., driving, cooking, etc.). An innovative way to improve executive function may be Assisted Cycling Therapy (ACT). This is among the first studies to use a Stroop task to measure inhibition, selective attention, and information processing speed following ACT in stroke survivors. Twenty-three participants post-stroke performed ACT, voluntary cycling (VC) and no cycling (NC). The results showed that there were improvements in the Stroop task following an acute session of ACT but not following VC or NC. These results suggest that ACT resulted in increased afferent information which may have resulted in increased arousal and excitability in regions of the prefrontal cortex. These factors have been shown to improve executive function.
ContributorsCooper, Aspen (Author) / Ringenbach, Shannon (Thesis director) / Holzapfel, Simon (Committee member) / Barrett, The Honors College (Contributor)
Created2017-05