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- All Subjects: Forensics
- Creators: School of Mathematical and Natural Sciences
- Member of: Barrett, The Honors College Thesis/Creative Project Collection
Forensic science is tasked with using calculative thinking with scientifically accepted methods of measurement and detection as well as the meditative task of applying their data to messy, real-world events. In order to support my supposition of forensic scientists being hermeneutical workers, three paintings were created. The three paintings can be considered a tryptic of sorts due to the context in which they are presented: forensic science. They each tell a story that is weaved within each other – spatter indicating violence long past, the empty void of a body gone, and the cold decomposition of a victim found. It is the forensic scientist that must interpret each piece separately and is tasked with finding how and why they are put together. The hermeneutical work of the forensic scientist interpreting a crime scene uses the same methods as one who interprets text. A forensic scientist opens possibilities of meaning in the same way that Martin Heidegger’s hermeneutic circle does. There is interplay between the interpreter (the forensic scientist) and the text (the crime scene), questions are formed (what happened here?) and responses are made (evidence found at the scene). This question and response outlook is what make the forensic scientist a hermeneutic thinker.
The subcategory of evidence deemed trace evidence is frequently seen in crime scenes, and while it is commonly the smallest evidence around, that doesn’t stop it from greatly contributing to the findings at the scene. Blood evidence may be categorized into this group in certain cases at crime scenes, especially in cases of transfer between two objects or people. In this study, the transfer of blood across both porous and non-porous substrates was examined to determine the persistence of blood across both substrates. The resulting stains after each trial of transfers were tested with a presumptive blood test commonly used in crime labs, the Kastle-Meyer test. Throughout all trials of the experiment, it was determined that blood on a non-porous surface typically dries faster as long as there isn’t a pooling effect, which hinders the ability for a stain to be continuously transferred and detected by Kastle-Meyer. Conversely, porous substrates are more likely to absorb and retain the blood in the material, allowing the blood to be released when pressure is applied, causing the stain to transfer more easily and result in a stain that will produce a positive Kastle-Meyer result.
The ever-increasing importance of cancer and neurodegenerative diseases continues to grow as populations across the world are affected by death and aging. The vitamin A (RXR) and vitamin D (VDR) receptor pathways offer promising potential to aid in treatment of cancer and Alzheimer’s disease. This thesis discusses the potential application of novel analogs of Bexarotene (RXR agonist), MeTC7 (a new potent VDR antagonist), and vitamin D as possible therapeutics for cancer and Alzheimer’s disease.