Filtering by
- Creators: Department of Psychology
- Creators: Honeycutt, Claire
- Member of: Barrett, The Honors College Thesis/Creative Project Collection
movement to become faster, more accurate and efficient, declines with age. Initial skill acquisition is dominated by cortical structures; however as learning proceeds, literature from
rodents and songbirds suggests that there is a transition away from cortical execution. Recent
evidence indicates that the reticulospinal system plays an important role in integration and
retention of learned motor skills. The brainstem has known age-rated deficits including cell
shrinkage & death. Given the role of the reticulospinal system in skill acquisition and older
adult’s poor capacity to learn, it begs the question: are delays in the reticulospinal system
associated with older adult’s poor capacity to learn?
Our objective was to evaluate if delays in the reticulospinal system (measured via the
startle reflex) and corticospinal system (measured via Transcranial Magnetic Stimulation (TMS) are correlated to impairment of motor learning in older adults. We found that individuals with fast startle responses resembling those of younger adults show the most improvement and retention while individuals with delayed startle responses show the least. We also found that there was no relationship between MEP latencies and improvement and retention. Moreover, linear regression analysis indicated that startle onset latency exists within a continuum of learning outcomes suggesting that startle onset latency may be a sensitive measure to predict learning deficits in older adults. As there exists no method to determine an individual’s relative learning capacity, these results open the possibility of startle, which is an easy and inexpensive behavioral measure and can be used to determine learning deficits in older adults to facilitate better dosing during rehabilitation therapy.
Our objective was to evaluate if delays in the reticulospinal system (measured via the startle reflex) are correlated to impairment of motor learning in older adults. We found that individuals with fast startle responses resembling those of younger adults show the most learning and retention of that learning while individuals with delayed startle responses show the least. Moreover, linear regression analysis indicated that startle onset latency exists within a continuum of learning outcomes suggesting that startle onset latency may be a sensitive measure to predict learning deficits in older adults. As there exists no method to determine an individual’s relative learning capacity, these results open the possibility of startle, which is an easy and inexpensive behavioral measure, being used to predict learning deficits in older adults to facilitate better dosing during rehabilitation therapy.
Age is the most significant risk factor for cancer development in humans. The somatic mutation theory postulates that the accumulation of genomic mutations over time results in cellular function degradation which plays an important role in understanding aging and cancer development. Specifically, degradation of the mechanisms that underlie somatic maintenance can occur due to decreased immune cell function and genomic responses to DNA damage. Research has shown that this degradation can lead to the accumulation of mutations that can cause cancer in humans. Despite recent advances in our understanding of cancer in non-human species, how this risk factor translates across species is poorly characterized. Here, we analyze a veterinarian cancer dataset of 4,178 animals to investigate if age related cancer prevalence is similar in non-human animals. We intend for this work to be used as a primary step towards understanding the potential overlap and/or uniqueness between human and non-human cancer risk factors. This study can be used to better understand cancer development and how evolutionary processes have shaped somatic maintenance across species.
Aging is a universal process that every being encounters on their journey of life. The effect of dance as a form of improvement of physical and well-being on the aging body brings upon the question of the impact of somatic-based movement, specifically gestural movement on the perceptions of aging within older and younger adults through a bi-cultural lens of the United States and India. This was investigated using a series of creative partnership workshops that included listening, drawing, and culminating movement activities, followed by a group discussion about the creative process. There were four different participant groups: a group of college students taking an Aging in American Culture collegiate class, a Somatic Practices collegiate dance class, a group of older adults at the Tempe Multigenerational Center, and a group of older adults in Bangalore, India. Inter-generational and cross-cultural observations were discussed, and it was seen that the workshops were able to foster feelings of community and camaraderie among participants depending on the group’s relationship to dance-making. From the research, a dance performance was developed and performed specifically with women of color in ASU’s Dance program with the choreographic process discussed in detail, along with key takeaways about facilitating a multi-dimensional experience for the dancers and choreographer. Future directions for the work include working with intergenerational populations and researching community effects on gendered aging experiences across cultures in the dance world.