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The aim of this case study was to help MH, a young adult male with Down syndrome, lose weight and improve his health. Initially he was morbidly obese, suffering from physical, mental, emotional, and health-related side effects. MH and his mother requested help from Dr. Shannon Ringenbach, and resided in

The aim of this case study was to help MH, a young adult male with Down syndrome, lose weight and improve his health. Initially he was morbidly obese, suffering from physical, mental, emotional, and health-related side effects. MH and his mother requested help from Dr. Shannon Ringenbach, and resided in Arizona for four months during the process of developing and implementing a program of diet and exercise for him. We created a plan to maximize weight loss in this short period of time. Overall, MH reduced his weight from 276 lbs. to 217 lbs. in four months, his lowest weight being 201 lbs. after he and his mother returned home to Oregon. This is a 75 lb. weight loss and body mass index (BMI) reduction of 13.7 kg/m2. Although to reach a healthy body weight MH would still need to continue his weight loss, this is a significant amount of weight, which is especially difficult for people with Down syndrome to lose. In this case study it was crucial to take into consideration the other aspects that affect weight gain and loss, such as motivation, family life, diet, and lifestyle.
ContributorsBrennan, Julia (Co-author) / Wright, Berlin (Co-author) / Ringenbach, Shannon (Thesis director) / Shaibi, Gabriel (Committee member) / Chen, Chih-Chia (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2013-05
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Description
Cannabis use has been purported to cause an amotivation-like syndrome among users. The purpose of this study was to investigate whether third party observers noticed amotivation among cannabis users. Participants in this study were 72 undergraduate university students, with a mean age of M=19.20 years old (SD=2.00). Participants nominated Informants

Cannabis use has been purported to cause an amotivation-like syndrome among users. The purpose of this study was to investigate whether third party observers noticed amotivation among cannabis users. Participants in this study were 72 undergraduate university students, with a mean age of M=19.20 years old (SD=2.00). Participants nominated Informants who knew them well and these informants completed a version of the 18-item Apathy Evaluation Scale. Results indicated that more frequent cannabis use was associated with higher informant-reported levels of amotivation, even when controlling for age, sex, psychotic-like experiences, SES, alcohol use, tobacco use, other drug use, and depression symptoms (β=0.34, 95% CI: 0.04, 0.64, p=.027). A lack of motivation severe enough to be visible by a third party has the potential to have negative social impacts on individuals who use cannabis regularly.
ContributorsWhite, Makita Marie (Author) / Meier, Madeline (Thesis director) / Glenberg, Arthur (Committee member) / Pardini, Dustin (Committee member) / School of Art (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Vitamin B12, found only in animal products, is a water-soluble vitamin important for DNA methylation, purine and pyrimidine synthesis, and the myelination of nerves. Symptoms of vitamin B12 deficiency include anemia, gait disturbances, altered vibration proprioception, impaired vision, psychosis, depression, dementia-like illness, and ultimately death. Because vegetarians and

Vitamin B12, found only in animal products, is a water-soluble vitamin important for DNA methylation, purine and pyrimidine synthesis, and the myelination of nerves. Symptoms of vitamin B12 deficiency include anemia, gait disturbances, altered vibration proprioception, impaired vision, psychosis, depression, dementia-like illness, and ultimately death. Because vegetarians and vegans consume fewer animal products in their diet than omnivores, they are inherently more at risk for developing these symptoms of vitamin B12 deficiency. Thus, the purpose of this study is to examine the correlation between nervous system markers (balance, dexterity, and vibration sensitivity) and markers of vitamin B12 nutriture (serum B12 and serum holo-transcobalamin II) in a cross-sectional study (n=38). In addition, the impact of daily oral vitamin B12 supplementation on these markers in an 8-week randomized controlled trial was also examined (n=18). The results of the cross-sectional study revealed a moderate correlation (R=-0.351, p=0.031) between serum B12 and left-hand functional dexterity. The results of the intervention study revealed no significant time*group interactions for markers of nervous system functions and biochemical values (after the removal of outliers). In addition, the time*group interaction appeared to be larger for those individuals with a baseline serum B12 of less than 303 pmol/L. These results suggest that vitamin B12 supplementation may have a more pronounced effect on those individuals who are in a state of vitamin B12 depletion (<303 pmol/L serum concentration). In addition, the results also suggest that 8 weeks of oral supplementation is not a long enough period to create significant clinical change, and it is likely that improvements in neurological measures would require long-term supplementation.
ContributorsArnold, Taylor (Author) / Johnston, Carol (Thesis advisor) / Whisner, Corrie (Committee member) / Ohri-Vachaspati, Punam (Committee member) / Lee, Chong (Committee member) / Aleck, Kyrieckos (Committee member) / Arizona State University (Publisher)
Created2016
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Description
The aim of this study is to evaluate whether or not fitness can be determined using a well-researched six minute walk test (6MWT) in a young adult population with Down syndrome (DS). This holds importance in today's health industry because this particular target group is at high risk for several

The aim of this study is to evaluate whether or not fitness can be determined using a well-researched six minute walk test (6MWT) in a young adult population with Down syndrome (DS). This holds importance in today's health industry because this particular target group is at high risk for several cardiovascular, cognitive and clinical factors that contribute to their well-being and longevity. As well, the findings of this research could potentially contribute to the low volume of research that currently exists regarding fitness and the DS population and provide pertinent knowledge towards intervention programs. Fourteen participants with DS performed one 6MWT at a self-selected rate during an exercise intervention study to assess physical fitness. The results showed that walk distance increased with decreased BMI and walk distance increased with increased walking speed and increased leisure activity. These findings are clear indicators of physical fitness relating to healthy physical behavior. All results were consistent with past research in specific at-risk health related populations. This data suggests that this physical test is an adequate indicator of fitness levels in populations with DS, which may additionally provide explicit avenues for intervention and treatment to improve health.
ContributorsMoss Hunt, Lauren Charlie (Author) / Ringenbach, Shannon (Thesis director) / Shaibi, Gabriel (Committee member) / Maraj, Brian (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2013-05