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- All Subjects: Brain
- All Subjects: Integrative Health
- Creators: Edson College of Nursing and Health Innovation
- Creators: Stabenfeldt, Sarah
- Status: Published
Over-the-counter (OTC) analgesics, omega-3 fatty acids, specialized pro-resolving mediators (SPMs), and remote ischemic conditioning (RIC) were administered before or following midline fluid percussion injury. Behavioral, histological, and molecular analyses were used to assess treatment effects on functional outcome and secondary injury progression. Acute administration of common OTC analgesics had little effect on post-injury outcome in mice. Dietary supplementation with omega-3 fatty acid docosahexaenoic acid (DHA) prior to or following diffuse TBI significantly reduced injury-induced sensory sensitivity and markers of neuroinflammation with no effect on spatial learning. Intraperitoneal administration of omega-3 fatty acid-derived SPM resolvin E1 significantly increased post-injury sleep and suppressed microglial activation. Aspirin-triggered (AT) resolvin D1 administration improved both motor and cognitive outcome following diffuse TBI. RIC treatment in mice demonstrated little effect on functional outcome from diffuse TBI. Untargeted proteomic analysis of plasma samples from RIC-treated mice was used to identify candidate molecular correlates of RIC. Identification of these candidates represents a vital first step in elucidating the neuroprotective mechanisms underlying RIC. The overall findings suggest that omega-3 fatty acid supplementation, SPM administration, and RIC may serve as effective practical therapies to reduce the somatic, cognitive, and neurological burden of diffuse TBI felt by millions of Americans.
In this quantitative research paper, we explored the correlation between the six dimensions of motivation as part of the Self-Determination Theory spectrum and physical activity. In addition, our aim was to also see if Transcranial Direct Current Stimulation (tDCS) paired with exercise as an intervention would affect motivation to exercise over time.
In this quantitative research paper, we explored the correlation between the six dimensions of motivation as part of the Self-Determination Theory spectrum and physical activity. In addition, our aim was to also see if Transcranial Direct Current Stimulation (tDCS) paired with exercise as an intervention would affect motivation to exercise over time.
It is often a passion for caring for others that drives people towards the profession of nursing in the first place. At some point, however, this desire to care for other people takes over, and nurses soon forget how to properly care for themselves. It was asked: If students are better prepared with and more encouraged to use healthy coping mechanisms and integrative modalities to deal with their daily lives, are they more likely to continue to care for themselves properly as time goes on? Ample research was conducted illuminating the prevalence of this worldwide problem and highlighting potential solutions noted by credible sources. An initiative was formed with the goal of improving the self care practices of nursing students at Arizona State University (ASU) with the greater intent of promoting a healthier work environment as these students advance into their future careers. The Arizona Student Chapter of the American Holistic Nurses Association (AHNA) at ASU was formed, and it serves as the vessel for this self-care health-care mission.
Time-Lapse Visualization of Microglia Cell Processes using Fluorescent Miniature (Miniscope) Imaging
The purpose of this project was to develop a student-led holistic nurses chapter as a space where students can learn to apply mind-body based modalities into their routine, accommodating their unique lifestyle. This paper aims to discuss the process of implementing a student-led holistic chapter. From this project further discussion can be completed in regards to policy, practice, research, and inclusion. Policy can be developed in regards to student-driven processes and procedures of the new chapter. This experience can translate to nurses who develop policy in the practice setting. Practice focus can be implemented within the chapter as self-care application and how to bring knowledge to patients in the clinical setting. Research studies can measure the effectiveness of the chapter in regards to student stress levels and academic improvement. Inclusion is a unique part of this initiative as the goal is to grow the student-led organization by inviting nursing students from all schools in the state. Inclusion of leaders from the American Holistic Nurses Association in mentoring and supporting the initiatives is critical.