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- Creators: Harrington Bioengineering Program
In cases where surgical repair is insufficient to return the heart to normal function, a patient may proceed to advanced heart failure, and a heart transplant may be required. Unfortunately, a finite number of available donor hearts are available. A mechanical circulatory support (MCS) device can be used to bridge the time between heart failure and reception of a donor heart. These MCS devices are typically constructed for the adult population. Accordingly, the size associated to the device is a limiting factor for small adults or pediatric patients who often have smaller thoracic measurements. While current eligibility criteria are based on correlative measurements, the aforementioned 3D visualization capabilities can be leveraged to accomplish patient-specific fit analysis.
The main objectives of the work presented in this dissertation were 1) to develop and evaluate an optimized process for 3D printing cardiovascular anatomy for surgical planning and medical education and 2) to develop and evaluate computational tools to assess MCS device fit in specific patients. The evaluations for objectives 1 and 2 were completed with a collection of qualitative and quantitative validations. These validations include case studies to illustrate meaningful, qualitative results as well as quantitative results from surgical outcomes. The latter results present the first quantitative supporting evidence, beyond anecdotal case studies, regarding the efficacy of 3D printing for pre-procedural planning; this data is suitable as pilot data for clinical trials. The products of this work were used to plan 200 cardiovascular procedures (including 79 cardiothoracic surgeries at Phoenix Children's Hospital), via 3D printed heart models and assess MCS device fit in 29 patients across 6 countries.
3D printing prosthetics for amputees is an innovative opportunity to provide a lower cost and customized alternative to current technologies. Companies, such as E-NABLE and YouBionic are developing myoelectric prosthetics, electrically powered terminal devices activated by electromyography (EMG), for transradial amputees. Prosthetics that are 3D printed are less expensive for juvenile use, more sustainable, and more accessible for those without insurance. Although they are typically not outfitted with the same complex grip patterns or durability of a traditional myoelectric prosthetic, they offer a sufficient durability (withstanding up to 150 N on average) and allow for new opportunities in prosthetic development. Devils Prosthetics, a student research and development group associated with Engineering Projects in Community Service (EPICS), has investigated the benefits and pitfalls of utilizing polyethylene terephthalate glycol (PETG) for 3D printing prosthetics as well as combining a MyoWare EMG sensor with machine learning for optimal control of the prosthetic.
3D printing prosthetics for amputees is an innovative opportunity to provide a lower cost and customized alternative to current technologies. Companies, such as E-NABLE and YouBionic are developing myoelectric prosthetics, electrically powered terminal devices activated by electromyography (EMG), for transradial amputees. Prosthetics that are 3D printed are less expensive for juvenile use, more sustainable, and more accessible for those without insurance. Although they are typically not outfitted with the same complex grip patterns or durability of a traditional myoelectric prosthetic, they offer a sufficient durability (withstanding up to 150 N on average) and allow for new opportunities in prosthetic development. Devils Prosthetics, a student research and development group associated with Engineering Projects in Community Service (EPICS), has investigated the benefits and pitfalls of utilizing polyethylene terephthalate glycol (PETG) for 3D printing prosthetics as well as combining a MyoWare EMG sensor with machine learning for optimal control of the prosthetic.
3D printing prosthetics for amputees is an innovative opportunity to provide a lower cost and customized alternative to current technologies. Companies, such as E-NABLE and YouBionic are developing myoelectric prosthetics, electrically powered terminal devices activated by electromyography (EMG), for transradial amputees. Prosthetics that are 3D printed are less expensive for juvenile use, more sustainable, and more accessible for those without insurance. Although they are typically not outfitted with the same complex grip patterns or durability of a traditional myoelectric prosthetic, they offer a sufficient durability (withstanding up to 150 N on average) and allow for new opportunities in prosthetic development. Devils Prosthetics, a student research and development group associated with Engineering Projects in Community Service (EPICS), has investigated the benefits and pitfalls of utilizing polyethylene terephthalate glycol (PETG) for 3D printing prosthetics as well as combining a MyoWare EMG sensor with machine learning for optimal control of the prosthetic.