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Early childhood environment is critical to subsequent physical health in children and is influenced by children's primary caregivers \u2014 typically mothers. Maternal stress, one aspect of a child's environment, may shape the functioning of the child's physiological stress response system, which has been linked to later health outcomes, including pain.

Early childhood environment is critical to subsequent physical health in children and is influenced by children's primary caregivers \u2014 typically mothers. Maternal stress, one aspect of a child's environment, may shape the functioning of the child's physiological stress response system, which has been linked to later health outcomes, including pain. The current study evaluated whether: 1) early maternal stress, defined as maternal depressive symptoms and low socio-economic status, predicts later child pain; 2) early maternal stress relates to later child daily cortisol output; and 3) child's cortisol output across the day mediates the relation between early maternal stress and child pain. Maternal stress was assessed via questionnaires at twin age 12-months. At twin age seven years, twins' salivary cortisol was collected three times per day for three days. At twin age nine years, twins rated how often they experienced stomach, headache, and back pain weekly or more frequently. Results of multilevel linear and logistic regression analyses showed that early maternal stress did not predict later children's daily cortisol output or extent of child pain. Therefore, findings were inconsistent with the proposed mediation model. However, there was a marginally significant negative relation between child daily cortisol output and later extent of child pain. Current findings suggest that functioning of the stress response system, reflected in cortisol output, may have implications for the development of child pain. Future work evaluating intensely stressful early environments may provide clues about the links between a child's early environment and the development of his/her stress response system.
ContributorsRoth, Winter Rayne Nicole (Author) / Davis, Mary (Thesis director) / Miadich, Samantha (Committee member) / Department of Psychology (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Description
Research has shown that environmental stressors that occur during childhood and early adolescence are associated with multiple deficits in physiological and psychological functioning later in life. The hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a potential biological mechanism through which these phenotypic alterations occur as studies have shown a link

Research has shown that environmental stressors that occur during childhood and early adolescence are associated with multiple deficits in physiological and psychological functioning later in life. The hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a potential biological mechanism through which these phenotypic alterations occur as studies have shown a link between early life adversity and altered diurnal cortisol patterns (Goldman-Mellor, Hamer, & Steptoe, 2012; Gunnar & Quevedo, 2008). Given research has shown that diurnal cortisol levels are influenced by genetic factors (Veen et al., 2011), but that a majority of differences across subjects can be attributed to the environment (Schreiber et al., 2006), phenotypic associations were explored between the quality of the home environment and children's diurnal cortisol patterns. The first aim of this study was to determine the level of genetic and environmental contributions to different parameters of diurnal cortisol rhythm. The second aim of this study was to examine whether the quality of the home environment, particularly indicators involving parenting and the physical environment, was associated with these same diurnal cortisol measures. A diverse sample of 320 twin children were assessed at 8 years using gold standard home environment interviews and a measure of diurnal cortisol rhythm across three days with three samples taken from each twin every day. Twin intraclass correlations indicated high levels of heritability for the morning to afternoon diurnal cortisol slope as well as the afternoon to evening slope, while measures of cortisol in the afternoon, evening, and across the day showed low levels of heritability, which suggested that differences in the environment were a more influential factor. Multilevel regression analyses showed that the overall quality of the home environment was found to be significantly negatively associated with cortisol levels at bedtime and negatively associated across the morning to afternoon slope at a trend level. The physical environment and emotional climate of the home were not significantly associated with any indicators of the diurnal cortisol pattern. A unique seasonality effect was noted as cortisol measurements taken from participants during the summer were significantly increased when compared to participants throughout the rest of the year. Overall, these findings showed a unique association between the quality of the home environment and diurnal cortisol levels at bedtime and perhaps the change in cortisol levels across the morning to afternoon, as well as a possible seasonal covariate which may affect diurnal cortisol measurements and one which often goes overlooked in cortisol research.
Created2018-05
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Description
School racial/ethnic diversity has been linked to positive developmental outcomes for youth in early adolescence (Graham, 2018). The purpose of this study was to examine whether school diversity and co-ethnic representation was associated with academic outcomes of children in middle childhood. Given mixed findings in previous research, this study

School racial/ethnic diversity has been linked to positive developmental outcomes for youth in early adolescence (Graham, 2018). The purpose of this study was to examine whether school diversity and co-ethnic representation was associated with academic outcomes of children in middle childhood. Given mixed findings in previous research, this study explored whether the effects of school diversity and co-ethnic representation on academic achievement were moderated by the ethnicity of the individual in a sample of twins in middle childhood (N=485; Mage= 8 8.36 years, SD = .62). Parent-report, teacher-report, and objective ratings of academic outcomes were used. Results indicated that school diversity was positively and significantly associated with teacher reported achievement (b = .80, p < .05) across the full sample. Moderation analyses suggest that greater school diversity was associated with lower parent-reported and objective academic scores for European American youth, but higher teacher-reported and objective academic outcomes for ethnic minority youth. Results indicated that, across the full sample, co-ethnic representation was significantly and negatively associated with one measure of objective academic outcomes (b = -7.99, p < .05). Contrary to hypotheses, greater co-ethnic representation was associated with better teacher-reported and objective academic outcomes for European American youth, but lower objective academic outcomes for ethnic minority children. Findings demonstrate that the ethnic composition of schools are associated with academic outcomes of children in middle childhood, but findings vary by measurement of diversity (i.e., diversity index vs. co-ethnic representation and by the child’s own race/ethnicity.
ContributorsEzeh, Dirichi (Author) / Doane, Leah (Thesis director) / Lemery, Kathyrn (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05