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With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender ga

With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender gap is closing due to more advanced screening and a better understanding of how females with ASD present their symptoms. Little research has been published on the neurocognitive differences that exist between older adults with ASD compared to neurotypical (NT) counterparts, and nothing has specifically addressed older women with ASD. This study utilized neuroimaging and neuropsychological tests to examine differences between diagnosis and sex of four distinct groups: older men with ASD, older women with ASD, older NT men, and older NT women. In each group, hippocampal size (via FreeSurfer) was analyzed for differences as well as correlations with neuropsychological tests. Participants (ASD Female, n = 12; NT Female, n = 14; ASD Male, n = 30; NT Male = 22), were similar according to age, IQ, and education. The results of the study indicated that the ASD Group as a whole performed worse on executive functioning tasks (Wisconsin Card Sorting Test, Trails Making Test) and memory-related tasks (Rey Auditory Verbal Learning Test, Weschler Memory Scale: Visual Reproduction) compared to the NT Group. Interactions of sex by diagnosis approached significance only within the WCST non-perseverative errors, with the women with ASD performing worse than NT women, but no group differences between men. Effect sizes between the female groups (ASD female vs. NT female) showed more than double that of the male groups (ASD male vs. NT male) for all WCST and AVLT measures. Participants with ASD had significantly smaller right hippocampal volumes than NT participants. In addition, all older women showed larger hippocampal volumes when corrected for total intracranial volume (TIV) compared to all older men. Overall, NT Females had significant correlations across all neuropsychological tests and their hippocampal volumes whereas no other group had significant correlations. These results suggest a tighter coupling between hippocampal size and cognition in NT Females than NT Males and both sexes with ASD. This study promotes further understanding of the neuropsychological differences between older men and women, both with and without ASD. Further research is needed on a larger sample of older women with and without ASD.
ContributorsWebb, Christen Len (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2019
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Description
The increase of Traumatic Brain Injury (TBI) cases in recent war history has increased the urgency of research regarding how veterans are affected by TBIs. The purpose of this study was to evaluate the effects of TBI on speech recognition in noise. The AzBio Sentence Test was completed for signal-to-noise

The increase of Traumatic Brain Injury (TBI) cases in recent war history has increased the urgency of research regarding how veterans are affected by TBIs. The purpose of this study was to evaluate the effects of TBI on speech recognition in noise. The AzBio Sentence Test was completed for signal-to-noise ratios (S/N) from -10 dB to +15 dB for a control group of ten participants and one US military veteran with history of service-connected TBI. All participants had normal hearing sensitivity defined as thresholds of 20 dB or better at frequencies from 250-8000 Hz in addition to having tympanograms within normal limits. Comparison of the data collected on the control group versus the veteran suggested that the veteran performed worse than the majority of the control group on the AzBio Sentence Test. Further research with more participants would be beneficial to our understanding of how veterans with TBI perform on speech recognition tests in the presence of background noise.
ContributorsCorvasce, Erica Marie (Author) / Peterson, Kathleen (Thesis director) / Williams, Erica (Committee member) / Azuma, Tamiko (Committee member) / Barrett, The Honors College (Contributor) / Department of Speech and Hearing Science (Contributor)
Created2015-05
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Description
In this creative thesis, I traveled to India and used my month long summer vacation back home to interview people about mental health in India. I talked to a therapist and four students about depression to find out what the situation is in India, contributing factors, experiences and stigma unique

In this creative thesis, I traveled to India and used my month long summer vacation back home to interview people about mental health in India. I talked to a therapist and four students about depression to find out what the situation is in India, contributing factors, experiences and stigma unique to depression among students in India, what the government is doing, and possible solutions or steps that can be taken to help students struggling with mental health problems. I also went to mainstream and special schools to meet special educators who work with differently abled children, occupational therapists, parents of differently abled children, and a student with Asperger’s in Chennai, Tamil Nadu to find out about the stigma surrounding differently abled children and their education path.
My efforts have culminated in the creation of the website mentalhealthinindia.com that can be used as a resource both by people in India as well as those abroad who are curious to learn about the stigma surrounding depression and differently abled children in India.
ContributorsVenkatakrishnan, Ranjani (Author) / Koester, Nicole (Thesis director) / Pruitt, Rhonda (Committee member) / Walter Cronkite School of Journalism & Mass Comm (Contributor) / School of International Letters and Cultures (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Token economies are a type of behavioral reinforcement that are particularly useful in classroom settings for increasing student compliance, for both typically developing children and children with autism spectrum disorder. During this study, we implemented a token economy in an inclusive preschool classroom with tokens contingent on compliance to classroom

Token economies are a type of behavioral reinforcement that are particularly useful in classroom settings for increasing student compliance, for both typically developing children and children with autism spectrum disorder. During this study, we implemented a token economy in an inclusive preschool classroom with tokens contingent on compliance to classroom rules. Three participants, two with a diagnosis of autism spectrum disorder and one considered typically developing, were included in the study. Results indicated that levels of compliance increased for both the typically developing participant and participants with autism, and did not drop below baseline levels during the withdrawal phase, suggesting there was no lack of intrinsic motivation. Further, the typically developing participant and one of the participants with autism spectrum disorder had very similar levels of compliance, while the other participant had much higher levels of compliance throughout every phase, suggesting that the compliance levels for peers with more advanced repertoires with autism may differ from both typically developing peers and peers who have less developed repertoires. The implications of these results are discussed as they relate to compliance from an ABA perspective.
ContributorsEggen, Kelly (Author) / Hahs, Adam (Thesis director) / Cavanaugh Toft, Carolyn (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Description
Adults with autism spectrum disorder (ASD) commonly have co-morbid psychiatric symptoms which can decrease quality of life. Although many adults with ASD are achieving greater independence, including attending college, psychiatric symptoms are generally not well controlled in this group. Mindfulness Based Stress Reduction (MBSR) is a program that has successfully

Adults with autism spectrum disorder (ASD) commonly have co-morbid psychiatric symptoms which can decrease quality of life. Although many adults with ASD are achieving greater independence, including attending college, psychiatric symptoms are generally not well controlled in this group. Mindfulness Based Stress Reduction (MBSR) is a program that has successfully been used to reduce the stress, depression, and anxiety symptoms in many clinical and non-clinical groups and may also be effective for college-aged students with ASD. The present investigation assessed the demand, practicality, implementation, adaptation, and acceptability of an MBSR course for college students with ASD. A total of 22 participants completed the questionnaire containing 53 questions and were between the ages of 18 to 64. We found that the MBSR therapy is in high demand for individuals with ASD, and that the participants would be willingly complete the intervention techniques. Participants generally stated that a therapy course like MBSR may help reduce their symptoms, and that they were eager to enroll. Participants were willing to attend all 8 classes during the summer, with a preference for afternoons. Also, modifications including yoga and background music would be accepted by each participant as well as any additional modifications made to the course to meet the needs of the individuals with ASD. Next steps include enrolling and randomizing students into the MBSR course or control group, as well as collect pre- and post-intervention data. We hypothesize MBSR will reduce the psychiatric symptoms and stress levels of individuals in college with ASD, demonstrating its effectiveness in this vulnerable population.
ContributorsJones, Rachel Michelle (Author) / Braden, Blair (Thesis director) / Baxter, Leslie (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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An investigation of the Caregiver Autism Residential E-health (CARE) system composed of low-cost, end-user deployable smart home technology and accompanying heuristics for rule-based models of human behavior has been evaluated for its potential as an empowering assistive technology with the capacity to enhance the well-being of people living with autism,

An investigation of the Caregiver Autism Residential E-health (CARE) system composed of low-cost, end-user deployable smart home technology and accompanying heuristics for rule-based models of human behavior has been evaluated for its potential as an empowering assistive technology with the capacity to enhance the well-being of people living with autism, their caregivers, and family members. It allows adults living with autism to create personalized smart home interventions that provide motivational support and is accompanied by guidelines for a safe and effective means of behavioral change. This investigation contributes a participatory co-design approach which addresses both the role of flexibility for the dynamic needs of the individual while offering strategies for dealing with the challenges of designing assistive smart home technologies for the needs of individuals across the wide range of autism spectrum disorders.
ContributorsNewman, Naomi Catton (Author) / Burleson, Winslow (Thesis director) / Brotman, Ryan (Co-author) / Lozano, Cecil (Co-author) / Adams, Jim (Committee member) / Zautra, Alex (Committee member) / Barrett, The Honors College (Contributor) / Graduate College (Contributor) / School of Community Resources and Development (Contributor) / Department of Psychology (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2013-05
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Description

The purpose of this project was to research the expression of Autism Spectrum Disorder in children and create a children’s book that can help the peers of individuals with a diagnosis to understand what the disorder entails and potentially gain a new sense of empathy for peers of all levels

The purpose of this project was to research the expression of Autism Spectrum Disorder in children and create a children’s book that can help the peers of individuals with a diagnosis to understand what the disorder entails and potentially gain a new sense of empathy for peers of all levels of physical and mental abilities. The research component includes interviews with individuals deemed knowledgeable about ASD, including occupational therapists, behavioral analysts, and parents, as well as a literature review of research studies on the expression of Autism in children. This written portion of the project may also serve as a manual for individuals who have little to no knowledge of ASD, as it dives deeper into the content of the book and research, while remaining easily understandable and clear to those without any prior knowledge or experience with ASD. It could prove especially useful for those in professions that come into contact with individuals with Autism, but do not necessarily require psychology courses or training as a prerequisite for the role, such as teachers and some health professionals.

ContributorsSigna, Hope (Author) / Nelson, Elizabeth (Thesis director) / Spinrad, Tracy (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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This research paper covers many topics related to autism, including causes, treatment, DSM changes, and more. It is a review of current literature and journals and aims to give the audience a better understanding of the disorders and to discuss the changes in diagnostic criteria and prevalence of ASD.

ContributorsPeters, Emily Morgan (Author) / Stenhoff, Donald (Thesis director) / Hahs, Adam (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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In this thesis I will explore deficits in Theory of Mind (ToM) in autistic people due to new evidence that they do not completely lack a ToM. A new theory is proposed, claiming that autistic people use a Hyper Theory of Mind (HyperToM) which has some application and processing differences

In this thesis I will explore deficits in Theory of Mind (ToM) in autistic people due to new evidence that they do not completely lack a ToM. A new theory is proposed, claiming that autistic people use a Hyper Theory of Mind (HyperToM) which has some application and processing differences from typical ToM. The HyperToM test will be administered as an online questionnaire that includes a self-reported Autism Quotient (AQ) section. The study is done in low support needs autistic (LSA) adults, which should have a developed ToM due to age and ability. Results showed some correlations with the AQ symptoms and HyperToM, but not enough diagnosed autistic people (9) participated in this study for significant results.

ContributorsMarkov, Vlada A (Author) / Fabricius, William (Thesis director) / Philips, Ben (Committee member) / Department of Psychology (Contributor) / Dean, W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description
Autism shows a pronounced and replicable sex bias with approximately three-to-four males diagnosed for every one female. Sex-related biology is thought to play a role in the sex bias, such that female biology may be protective and/or male biology may increase vulnerability to autism in the context of similar genetic

Autism shows a pronounced and replicable sex bias with approximately three-to-four males diagnosed for every one female. Sex-related biology is thought to play a role in the sex bias, such that female biology may be protective and/or male biology may increase vulnerability to autism in the context of similar genetic risk. Beyond etiology, sex-related biology has also been implicated in lifespan risk for health and psychiatric conditions that show common co-morbidity in autism. Thus, understanding how sex-related biology impacts autism etiology and progression has important implications for prognosis and treatment. Neuroimaging offers a powerful tool for in-vivo characterization of brain-based sex differences in autism, especially given emerging efforts to develop large, well-characterized longitudinal samples. To date, however, neuroimaging studies have shown mixed and inconsistent findings, which remain challenging to integrate in the broader literature context. In a recent systematic review of neuroimaging studies of typical sex differences, few to no replicable effects were found beyond brain size, suggesting the brain is not “sexually dimorphic.” Instead, it is argued that the brain is a “mosaic” of features from various sources, including masculine and feminine biological processes as well as individual genetics and environment. Thus, designing neuroimaging studies that are sensitive to brain-based sex differences in autism likely requires careful study design and analytical method selection. Through a series of studies, the overarching dissertation aim was to identify optimal methods for characterizing neuroimaging-based sex differences in autism and to test these methods in preliminary samples. Study 1 comprised a systematic review of studies examining neuroimaging-based sex differences in autism with the aim of identifying optimal study designs, neuroimaging modalities, and analytical methods. Study 2 focused on examining the sensitivity of a connectome-wide approach to identify functional connectivity hubs underlying sex-biased behavior associated with autism (e.g., camouflaging). Study 3 used a connectome-wide functional connectivity approach to characterize sex differences in longitudinal changes associated with autistic traits vs. categorical diagnosis. These studies suggest that optimizing study design and methods improves identification of biologically plausible and clinically meaningful brain sex differences in autism. The relevance of findings to etiology and prognosis are discussed.
ContributorsWalsh, Melissa (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Rogalsky, Corianne (Committee member) / Arizona State University (Publisher)
Created2022