Matching Items (14)
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- All Subjects: Autism
- All Subjects: Signal Processing
- Creators: Electrical Engineering Program
- Creators: Dixon, Maria
- Resource Type: Text
Description
With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender gap is closing due to more advanced screening and a better understanding of how females with ASD present their symptoms. Little research has been published on the neurocognitive differences that exist between older adults with ASD compared to neurotypical (NT) counterparts, and nothing has specifically addressed older women with ASD. This study utilized neuroimaging and neuropsychological tests to examine differences between diagnosis and sex of four distinct groups: older men with ASD, older women with ASD, older NT men, and older NT women. In each group, hippocampal size (via FreeSurfer) was analyzed for differences as well as correlations with neuropsychological tests. Participants (ASD Female, n = 12; NT Female, n = 14; ASD Male, n = 30; NT Male = 22), were similar according to age, IQ, and education. The results of the study indicated that the ASD Group as a whole performed worse on executive functioning tasks (Wisconsin Card Sorting Test, Trails Making Test) and memory-related tasks (Rey Auditory Verbal Learning Test, Weschler Memory Scale: Visual Reproduction) compared to the NT Group. Interactions of sex by diagnosis approached significance only within the WCST non-perseverative errors, with the women with ASD performing worse than NT women, but no group differences between men. Effect sizes between the female groups (ASD female vs. NT female) showed more than double that of the male groups (ASD male vs. NT male) for all WCST and AVLT measures. Participants with ASD had significantly smaller right hippocampal volumes than NT participants. In addition, all older women showed larger hippocampal volumes when corrected for total intracranial volume (TIV) compared to all older men. Overall, NT Females had significant correlations across all neuropsychological tests and their hippocampal volumes whereas no other group had significant correlations. These results suggest a tighter coupling between hippocampal size and cognition in NT Females than NT Males and both sexes with ASD. This study promotes further understanding of the neuropsychological differences between older men and women, both with and without ASD. Further research is needed on a larger sample of older women with and without ASD.
ContributorsWebb, Christen Len (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2019
Description
The world of a hearing impaired person is much different than that of somebody capable of discerning different frequencies and magnitudes of sound waves via their ears. This is especially true when hearing impaired people play video games. In most video games, surround sound is fed through some sort of digital output to headphones or speakers. Based on this information, the gamer can discern where a particular stimulus is coming from and whether or not that is a threat to their wellbeing within the virtual world. People with reliable hearing have a distinct advantage over hearing impaired people in the fact that they can gather information not just from what is in front of them, but from every angle relative to the way they're facing. The purpose of this project was to find a way to even the playing field, so that a person hard of hearing could also receive the sensory feedback that any other person would get while playing video games To do this, visual surround sound was created. This is a system that takes a surround sound input, and illuminates LEDs around the periphery of glasses based on the direction, frequency and amplitude of the audio wave. This provides the user with crucial information on the whereabouts of different elements within the game. In this paper, the research and development of Visual Surround Sound is discussed along with its viability in regards to a deaf person's ability to learn the technology, and decipher the visual cues.
ContributorsKadi, Danyal (Co-author) / Burrell, Nathaneal (Co-author) / Butler, Kristi (Co-author) / Wright, Gavin (Co-author) / Kosut, Oliver (Thesis director) / Bliss, Daniel (Committee member) / Barrett, The Honors College (Contributor) / Electrical Engineering Program (Contributor)
Created2015-05
Description
Detecting early signs of neurodegeneration is vital for measuring the efficacy of pharmaceuticals and planning treatments for neurological diseases. This is especially true for Amyotrophic Lateral Sclerosis (ALS) where differences in symptom onset can be indicative of the prognosis. Because it can be measured noninvasively, changes in speech production have been proposed as a promising indicator of neurological decline. However, speech changes are typically measured subjectively by a clinician. These perceptual ratings can vary widely between clinicians and within the same clinician on different patient visits, making clinical ratings less sensitive to subtle early indicators. In this paper, we propose an algorithm for the objective measurement of flutter, a quasi-sinusoidal modulation of fundamental frequency that manifests in the speech of some ALS patients. The algorithm detailed in this paper employs long-term average spectral analysis on the residual F0 track of a sustained phonation to detect the presence of flutter and is robust to longitudinal drifts in F0. The algorithm is evaluated on a longitudinal speech dataset of ALS patients at varying stages in their prognosis. Benchmarking with two stages of perceptual ratings provided by an expert speech pathologist indicate that the algorithm follows perceptual ratings with moderate accuracy and can objectively detect flutter in instances where the variability of the perceptual rating causes uncertainty.
ContributorsPeplinski, Jacob Scott (Author) / Berisha, Visar (Thesis director) / Liss, Julie (Committee member) / Electrical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This document introduces the need for the Rest Egg system and defines an accessible method of smartphone integration. Excessive noise can prevent recovering patients and special needs persons from resting correctly. The Rest Egg was designed for these people- people who are in critical need of quality rest but are often unable to eliminate stressors themselves. This system ensures their environment is calm by alerting caretakers' smartphones if noise reaches abrasive levels. Smartphones were the preferred device due to the wide spread of such devices in today's market. After making open sourcing a goal, something ubiquitous and affordable \u2014 yet usable and dependable \u2014 was necessary for the alert system. These requirements lead to the election an online alert service: Pushover, a trademark and product of Superblock, LLC.
ContributorsJennings, Tyler Blake (Author) / Goryll, Michael (Thesis director) / Kozicki, Michael (Committee member) / Barrett, The Honors College (Contributor) / Electrical Engineering Program (Contributor)
Created2016-05
Description
This paper analyzes existing literature regarding how excessive aggravating stimuli in a hospital environment can reduce the quality and quantity of sleep. The sick and injured are most sensitive to aggravating stimuli and the most vulnerable to poor sleep conditions. For individuals with anxiety, stress, hypersensitivity, or conditions such as Autism Spectrum Disorder (ASD), as additional stress during rest periods could seriously harm development and overall well-being. While solutions have been proposed and tested, there is no one solution to the problem. One possible solution is to design a device that monitors a patient's room and alerts a nurse or parent of aggravating stimuli so that it can be removed.
ContributorsKhan, Zarah Noor (Author) / Goryll, Michael (Thesis director) / Adams, James B. (Committee member) / Electrical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The increasing presence and affordability of sensors provides the opportunity to make novel and creative designs for underserved markets like the legally blind. Here we explore how mathematical methods and device coordination can be utilized to improve the functionality of inexpensive proximity sensing electronics in order to create designs that are versatile, durable, low cost, and simple. Devices utilizing various acoustic and electromagnetic wave frequencies like ultrasonic rangefinders, radars, Lidar rangefinders, webcams, and infrared rangefinders and the concepts of Sensor Fusion, Frequency Modulated Continuous Wave radar, and Phased Arrays were explored. The effects of various factors on the propagation of different wave signals was also investigated. The devices selected to be incorporated into designs were the HB100 DRO Radar Doppler Sensor (as an FMCW radar), HC-SR04 Ultrasonic Sensor, and Maxbotix Ultrasonic Rangefinder \u2014 EZ3. Three designs were ultimately developed and dubbed the "Rad-Son Fusion", the "Tri-Beam Scanner", and the "Dual-Receiver Ranger". The "Rad-Son Fusion" employs the Sensor Fusion of an FMCW radar and Ultrasonic sensor through a weighted average of the distance reading from the two sensors. The "Tri-Beam Scanner" utilizes a beam-forming Digital Phased Array of ultrasonic sensors to scan its surroundings. The "Dual-Receiver Ranger" uses the convolved result from to two modified HC-SR04 sensors to determine the time of flight and ultimately an object's distance. After conducting hardware experiments to determine the feasibility of each design, the "Dual-Receiver Ranger" was prototyped and tested to demonstrate the potential of the concept. The designs were later compared based on proposed requirements and possible improvements and challenges associated with the designs are discussed.
ContributorsFeinglass, Joshua Forster (Author) / Goryll, Michael (Thesis director) / Reisslein, Martin (Committee member) / Electrical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This pilot study evaluated whether Story Champs and Puente de Cuentos helped bilingual preschoolers increase their usage of emotional terms and ability to tell stories. Participants in this study included 10 Spanish-English bilingual preschoolers. Intervention was conducted in 9 sessions over 3 days using the Test of Narrative Retell to measure results. Results did not find significant gains in either emotional term usage or ability to tell stories, but the results were promising as a pilot study.
ContributorsSato, Leslie Mariko (Author) / Restrepo, Maria (Thesis director) / Dixon, Maria (Committee member) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
The Development of the Strengthening Skills Program for Autistic Adults: Feasibility & Acceptability
Description
The study focuses on the creation of the Strengthening Skills Program (SSP) and its feasibility and acceptability among autistic adults across the lifespan. Over the course of two years, the program has been developed and delivered to autistic adults with the aim of improving quality of life. The program included adapted social skills training from the UCLA Program for the Education and Enrichment of Relational Skills (PEERS) for young adults, adapted mindfulness training from Mindfulness-Based Stress Reduction, and custom executive skills training. Pre- and post-intervention acceptability questionnaires were gathered from 42 participants. Participants were separated into three groups (SSP, PEERS, and Delayed Treatment Control [DTC]; n=14 per group) stratified by age, gender, and if the participant had a program partner who would attend the program alongside as support. All groups were administered over Zoom once per week and lasted for 16 weeks each. The SSP group met for three hours each week and the PEERS group met for an hour and a half. Qualitative analysis was implemented on participant feedback to identify thematic codes related to their experiences with the programs. Overall, results suggest the SSP intervention had significantly higher acceptability ratings compared to PEERS alone and could be a useful addition to the limited interventions available for autistic adults.
ContributorsHill, Ethan Reed (Author) / Braden, Blair (Thesis advisor) / Matthews, Nicole (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2023
Description
Individuals with autism spectrum disorder (ASD) are known to show impairments in various domains of executive function (EF) such as behavioral flexibility or inhibitory control. Research suggests that EF impairment in adults with ASD may relate to ASD core symptoms, restrictive behaviors and social communication deficits. Mindfulness-based stress reduction (MBSR) has shown promise for improving EF abilities in neurotypical adults, but research has not explored its efficacy or neural mechanisms in adults with ASD. This pilot study examines the effects of an 8-week MBSR intervention on self-report measures of EF and resting-state functional connectivity in a sample of adults with ASD. Fifty-four participants were assigned either to an MBSR group (n = 29) or a social support group (n = 25). Executive function was measured using the BRIEF-2 before and after the intervention for the twenty-seven participants in the second cohort. MBSR-specific improvements in EF were found for BRIEF measures of initiation, inhibition, and working-memory. Resting-state fMRI data was analyzed using independent component analysis (ICA), and group by time resting-state functional connectivity differences were observed between the cerebellar network and frontal regions including the right frontal pole (rFP), medial frontal cortex (MFC) and left and right superior frontal gyri (SFG). The MBSR group showed increases in functional connectivity between the cerebellum and EF regions which correlated with improvements in BRIEF-2 measures. These findings suggest that MBSR may improve EF domains in adults with ASD, and that increases in functional connectivity between the cerebellum and frontal regions while at rest may be a mechanism for such improvements.
ContributorsGuerithault, Nicolas (Author) / Braden, B. Blair (Thesis advisor) / Rogalsky, Corianne (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2021
Description
The prevalence of Autism Spectrum Disorders (ASD) has resulted in research on treatment efficacy, lending itself to quantitative analyses. In contrast, ethnographic studies have offered the benefits of analyzing lived experiences and exploring the uniqueness of ASD individuals. Using the Linguistic Ethnography (LE) perspective, this case study investigates the connection between multilingual practices, behavior management, and behavior-logging app usage. It looks at one cross-cultural family (Indonesian-Belgian) with two children diagnosed with autism. Multimodal data were collected for ten weeks virtually and five weeks in the family’s home in Belgium. The data collection focused on the family's multilingual and behavior management practices and specifically on mobile app usage to document the behaviors of the non-verbal son. Analytical frameworks were drawn from Multimodal Ethnography (Dicks et al., 2006) and Multimodal Discourse Analysis (Kress, 2011a). The findings indicated that linguistic and cultural diversity, both internally and externally, caused a layer of complexity in attending to a non-verbal child. The case study showed positive outcomes of multilingualism. However, it highlighted the struggle of building consistent communication between family members and health professionals, which affected the effort to find a successful treatment plan. The behavior logging app helped parents identify parts of the son’s behaviors and reflect on their behavior management strategies. However, it also underscored the real-life challenges of documentation. In this case, mobile technology may be more useful when supported by health professionals. Although the case study notes family successes, it calls attention to the extraordinary realities of cross-cultural ASD families that need more representation through ethnographic research.
ContributorsQodri, Asri Nurul (Author) / Smith, David Bryan (Thesis advisor) / SturtzSreetharan, Cindi (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2023