Matching Items (17)
Filtering by
- All Subjects: Autism
- All Subjects: PTSD
- Creators: Sanford School of Social and Family Dynamics
- Creators: Azuma, Tamiko
- Creators: Krajmalnik-Brown, Rosa
- Member of: Theses and Dissertations
Description
The purpose of this project was to research the expression of Autism Spectrum Disorder in children and create a children’s book that can help the peers of individuals with a diagnosis to understand what the disorder entails and potentially gain a new sense of empathy for peers of all levels of physical and mental abilities. The research component includes interviews with individuals deemed knowledgeable about ASD, including occupational therapists, behavioral analysts, and parents, as well as a literature review of research studies on the expression of Autism in children. This written portion of the project may also serve as a manual for individuals who have little to no knowledge of ASD, as it dives deeper into the content of the book and research, while remaining easily understandable and clear to those without any prior knowledge or experience with ASD. It could prove especially useful for those in professions that come into contact with individuals with Autism, but do not necessarily require psychology courses or training as a prerequisite for the role, such as teachers and some health professionals.
ContributorsSigna, Hope (Author) / Nelson, Elizabeth (Thesis director) / Spinrad, Tracy (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
This is a study of the adaptive behaviors of individuals with Autism Spectrum Disorder using the Vineland II Adaptive Behavioral Scale (VABS-II). This scale was used to determine the overall functioning level of individuals with Autism Spectrum Disorder at the beginning, and will be used at the end, of a year-long study beginning at Arizona State University. This larger study is determining what the effects are, if any, of a combination of nutritional and dietary treatments in individuals with Autism Spectrum Disorder. However, this paper only examines the VABS-II results of forty-three participants in the study, as well as their hand-grip strength. It was found that individuals with Autism Spectrum Disorder are substantially delayed in all four domains (communication, daily living skills, social skills, and motor skills) of adaptive behaviors measured by the VABS-II, particularly in communication. This study will be completed in May 2013, when it will be determined what the effects of these treatments are, if any.
ContributorsAdams, Rebecca (Author) / Ingram-Waters, Mary (Thesis director) / Krajmalnik-Brown, Rosa (Committee member) / Pollard, Elena (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
Description
This research paper covers many topics related to autism, including causes, treatment, DSM changes, and more. It is a review of current literature and journals and aims to give the audience a better understanding of the disorders and to discuss the changes in diagnostic criteria and prevalence of ASD.
ContributorsPeters, Emily Morgan (Author) / Stenhoff, Donald (Thesis director) / Hahs, Adam (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Posttraumatic stress disorder is a psychiatric disorder that can develop after exposure to a traumatic event, and it can cause affected individuals to relive the associated event through flashbacks or nightmares. This project centers around the prevalence of PTSD in parents of infants admitted to the neonatal intensive care unit. Past research has shown that these parents are at increased risk of developing traumatic stress symptoms, with affliction rates as high as 53% in mothers and 33% in fathers (Hua et al., 2018). With this statistic as a catalyst, the present text has a variety of aims, all hinging on the goal of easing the NICU journey for parents. This thesis explores the different types of therapy used in the treatment of traumatic stress, with a focus on trauma-focused cognitive behavioral therapy (TF-CBT) and eye movement desensitization and reprocessing (EMDR) as these were shown to be the most effective in past research. A compilation of resources was also gathered that can now be distributed to NICU parents, including information on PTSD, how to access a therapist, and other helpful articles. An additional component of this project included the administration of a survey to NICU parents to gain a better understanding of their stress levels, what resources were most helpful to them, what barriers limited their ability to seek help, and their thoughts on a text-messaging resource service. Institutional IRB approval was received for this survey. The survey indicated that parents were very stressed when admitted to the NICU, but their stress levels tend to decrease over time. Parents also faced a variety of barriers, with the need to return to work or maintain a busy schedule being the most pervasive. Additionally, an analysis was completed on federal legislation relating to healthcare and the NICU experience. Furthermore, special considerations for limited English proficient (LEP) families were also considered. The paper concludes with steps that should be taken, in both research and action, to improve on the NICU experience for at-risk parents. The implementation of a text-messaging resource service for NICU parents was desired by survey respondents and is a recommended next step. Changes in policy surrounding insurance reform and longer, paid family leave would also be beneficial. Training of NICU staff on how to provide resources and communicate sensitively and effectively with parents is also crucial if the current situation is to be improved. There are definitive steps that should be taken immediately to ease the journey and provide comfort for NICU parents.
ContributorsBryant, Tyler (Co-author) / Beck, Kelsey (Co-author) / Puruhito, Krista (Thesis director) / Visconti, Kari (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / School of Politics and Global Studies (Contributor, Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Token economies are a type of behavioral reinforcement that are particularly useful in classroom settings for increasing student compliance, for both typically developing children and children with autism spectrum disorder. During this study, we implemented a token economy in an inclusive preschool classroom with tokens contingent on compliance to classroom rules. Three participants, two with a diagnosis of autism spectrum disorder and one considered typically developing, were included in the study. Results indicated that levels of compliance increased for both the typically developing participant and participants with autism, and did not drop below baseline levels during the withdrawal phase, suggesting there was no lack of intrinsic motivation. Further, the typically developing participant and one of the participants with autism spectrum disorder had very similar levels of compliance, while the other participant had much higher levels of compliance throughout every phase, suggesting that the compliance levels for peers with more advanced repertoires with autism may differ from both typically developing peers and peers who have less developed repertoires. The implications of these results are discussed as they relate to compliance from an ABA perspective.
ContributorsEggen, Kelly (Author) / Hahs, Adam (Thesis director) / Cavanaugh Toft, Carolyn (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
Adults with autism spectrum disorder (ASD) commonly have co-morbid psychiatric symptoms which can decrease quality of life. Although many adults with ASD are achieving greater independence, including attending college, psychiatric symptoms are generally not well controlled in this group. Mindfulness Based Stress Reduction (MBSR) is a program that has successfully been used to reduce the stress, depression, and anxiety symptoms in many clinical and non-clinical groups and may also be effective for college-aged students with ASD. The present investigation assessed the demand, practicality, implementation, adaptation, and acceptability of an MBSR course for college students with ASD. A total of 22 participants completed the questionnaire containing 53 questions and were between the ages of 18 to 64. We found that the MBSR therapy is in high demand for individuals with ASD, and that the participants would be willingly complete the intervention techniques. Participants generally stated that a therapy course like MBSR may help reduce their symptoms, and that they were eager to enroll. Participants were willing to attend all 8 classes during the summer, with a preference for afternoons. Also, modifications including yoga and background music would be accepted by each participant as well as any additional modifications made to the course to meet the needs of the individuals with ASD. Next steps include enrolling and randomizing students into the MBSR course or control group, as well as collect pre- and post-intervention data. We hypothesize MBSR will reduce the psychiatric symptoms and stress levels of individuals in college with ASD, demonstrating its effectiveness in this vulnerable population.
ContributorsJones, Rachel Michelle (Author) / Braden, Blair (Thesis director) / Baxter, Leslie (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The gastrointestinal (GI) tract is home to a complex and diverse microbial ecosystem that contributes to health or disease in many aspects. While bacterial species are the majority in the GI tract, their cohabitants, fungal species, should not be forgotten. Children with autism spectrum disorder (ASD) often suffer from GI disorders and associated symptoms, implying a role the bacterial and fungal gut microbiota play in maintaining human health. The irregularities in GI symptoms can negatively affect the overall quality of life or even worsen behavioral symptoms the children present. Even with the increase in the availability of next-generation sequencing technologies, the composition and diversities of fungal microbiotas are understudied, especially in the context of ASD. We therefore aimed to investigate the gut mycobiota of 36 neurotypical children and 38 children with ASD. We obtained stool samples from all participants, as well as autism severity and GI symptom scores to help us understand the effect the mycobiome has on these symptoms. By targeting the fungal internal transcribed spacer (ITS) and bacterial 16S rRNA V4 regions, we obtained fungal and bacterial amplicon sequences, from which we investigated the diversities, composition, and potential link between two different ecological clades. From fungal amplicon sequencing results, we observed a significant decrease in the observed fungal OTUs in children with ASD, implying a lack of potentially beneficial fungi in ASD subjects. We performed Bray-Curtis principal coordinates analysis and observed significant differences in fungal microbiota composition between the two groups. Taxonomic analysis showed higher relative abundances of Candida , Pichia, Penicillium , and Exophiala in ASD subjects, yet due to a large dispersion of data, the differences were not statistically significant. Interestingly, we observed a bimodal distribution of Candida abundances within children with ASD. Candida's relative abundance was not significantly correlated with GI scores, but children with high Candida relative abundances presented significantly higher Autism Treatment Evaluation Checklist (ATEC) scores, suggesting a role of Candida on ASD behavioral symptoms. Regarding the bacterial gut microbiota, we found marginally lower observed OTUs and significantly lower relative abundance of Prevotella in the ASD group, which was consistent with previous studies. Taken together, we demonstrated that autism is closely linked with a distinct gut mycobiota, characterized by a loss of fungal and bacterial diversity and an altered fungal and bacterial composition.
ContributorsPatel, Jigar (Author) / Krajmalnik-Brown, Rosa (Thesis director) / Kang, Dae Wook (Committee member) / Adams, James (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using wire mesh (6hr/daily) for five days with two days off before restraint resumed for three weeks for a total of 23 restraint days. The groups consisted of control (CON) with no restraint other than food and water restriction yoked to the restrained groups, stress immediate (STR-IMM), which were restrained then fear conditioned soon after the end of the IRS paradigm, and stress given a rest for 6 weeks before fear conditioning commenced (STR-R6). Rats were fear conditioned by pairing a 20 second tone with a footshock, then given extinction training for two days (15 tone only on each day). On the first day of extinction, all groups discriminated well on the first trial, but then as trials progressed, STR-R6 discriminated between tone and context less than did CON. On the second day of extinction, STR- IMM froze more to context in the earlier trials than compared to STR-R6 and CON. As trials progressed STR-IMM and STR-R6 froze more to context than compared to CON. Together, CON discriminated between tone and context better than did STR-IMM and STR-R6. Sucrose preference, novelty suppressed feeding, and elevated plus maze was performed after fear extinction was completed. No statistical differences were observed among groups for sucrose preference or novelty suppressed feeding. For the elevated plus maze, STR-IMM entered the open arms and the sum of both open and closed arms fewer than did STR- R6 and CON. We interpret the findings to suggest that the stress groups displayed increased hypervigilance and anxiety with STR-R6 exhibiting a unique phenotype than that of STR-IMM and CON.
ContributorsShah, Vrishti Bimal (Author) / Conrad, Cheryl (Thesis director) / Newbern, Jason (Committee member) / Judd, Jessica (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
An increasing number of military veterans are enrolling in college, primarily due to the Post-9/11 GI Bill, which provides educational benefits to veterans who served on active duty since September 11, 2001. With rigorous training, active combat situations, and exposure to unexpected situations, the veteran population is at a higher risk for traumatic brain injury (TBI), Post Traumatic Stress Disorder (PTSD), and depression. All of these conditions are associated with cognitive consequences, including attention deficits, working memory problems, and episodic memory impairments. Some conditions, particularly mild TBI, are not diagnosed or treated until long after the injury when the person realizes they have cognitive difficulties. Even mild cognitive problems can hinder learning in an academic setting, but there is little data on the frequency and severity of cognitive deficits in veteran college students. The current study examines self-reported cognitive symptoms in veteran students compared to civilian students and how those symptoms relate to service-related conditions. A better understanding of the pattern of self-reported symptoms will help researchers and clinicians determine the veterans who are at higher risk for cognitive and academic difficulties.
ContributorsAllen, Kelly Anne (Author) / Azuma, Tamiko (Thesis director) / Gallagher, Karen (Committee member) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Autism shows a pronounced and replicable sex bias with approximately three-to-four males diagnosed for every one female. Sex-related biology is thought to play a role in the sex bias, such that female biology may be protective and/or male biology may increase vulnerability to autism in the context of similar genetic risk. Beyond etiology, sex-related biology has also been implicated in lifespan risk for health and psychiatric conditions that show common co-morbidity in autism. Thus, understanding how sex-related biology impacts autism etiology and progression has important implications for prognosis and treatment. Neuroimaging offers a powerful tool for in-vivo characterization of brain-based sex differences in autism, especially given emerging efforts to develop large, well-characterized longitudinal samples. To date, however, neuroimaging studies have shown mixed and inconsistent findings, which remain challenging to integrate in the broader literature context. In a recent systematic review of neuroimaging studies of typical sex differences, few to no replicable effects were found beyond brain size, suggesting the brain is not “sexually dimorphic.” Instead, it is argued that the brain is a “mosaic” of features from various sources, including masculine and feminine biological processes as well as individual genetics and environment. Thus, designing neuroimaging studies that are sensitive to brain-based sex differences in autism likely requires careful study design and analytical method selection. Through a series of studies, the overarching dissertation aim was to identify optimal methods for characterizing neuroimaging-based sex differences in autism and to test these methods in preliminary samples. Study 1 comprised a systematic review of studies examining neuroimaging-based sex differences in autism with the aim of identifying optimal study designs, neuroimaging modalities, and analytical methods. Study 2 focused on examining the sensitivity of a connectome-wide approach to identify functional connectivity hubs underlying sex-biased behavior associated with autism (e.g., camouflaging). Study 3 used a connectome-wide functional connectivity approach to characterize sex differences in longitudinal changes associated with autistic traits vs. categorical diagnosis. These studies suggest that optimizing study design and methods improves identification of biologically plausible and clinically meaningful brain sex differences in autism. The relevance of findings to etiology and prognosis are discussed.
ContributorsWalsh, Melissa (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Rogalsky, Corianne (Committee member) / Arizona State University (Publisher)
Created2022