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Is it possible to treat the mouth as a natural environment, and determine new methods to keep the microbiome in check? The need for biodiversity in health may suggest that every species carries out a specific function that is required to maintain equilibrium and homeostasis within the oral cavity. Furthermore,

Is it possible to treat the mouth as a natural environment, and determine new methods to keep the microbiome in check? The need for biodiversity in health may suggest that every species carries out a specific function that is required to maintain equilibrium and homeostasis within the oral cavity. Furthermore, the relationship between the microbiome and its host is mutually beneficial because the host is providing microbes with an environment in which they can flourish and, in turn, keep their host healthy. Reviewing examples of larger scale environmental shifts could provide a window by which scientists can make hypotheses. Certain medications and healthcare treatments have been proven to cause xerostomia. This disorder is characterized by a dry mouth, and known to be associated with a change in the composition, and reduction, of saliva. Two case studies performed by Bardow et al, and Leal et al, tested and studied the relationships of certain medications and confirmed their side effects on the salivary glands [2,3]. Their results confirmed a relationship between specific medicines, and the correlating complaints of xerostomia. In addition, Vissink et al conducted case studies that helped to further identify how radiotherapy causes hyposalivation of the salivary glands [4]. Specifically patients that have been diagnosed with oral cancer, and are treated by radiotherapy, have been diagnosed with xerostomia. As stated prior, studies have shown that patients having an ecologically balanced and diverse microbiome tend to have healthier mouths. The oral cavity is like any biome, consisting of commensalism within itself and mutualism with its host. Due to the decreased salivary output, caused by xerostomia, increased parasitic bacteria build up within the oral cavity thus causing dental disease. Every human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease. The Human Oral Microbiomics Database (HOMD) is a set of reference 16S rRNA gene sequences. These are then used to define individual human oral taxa. By conducting metagenomic experiments at the molecular and cellular level, scientists can identify and label micro species that inhabit the mouth during parasitic outbreaks or a shifting of the microbiome. Because the HOMD is incomplete, so is our ability to cure, or prevent, oral disease. The purpose of the thesis is to research what is known about xerostomia and its effects on the complex microbiome of the oral cavity. It is important that researchers determine whether this particular perspective is worth considering. In addition, the goal is to create novel experiments for treatment and prevention of dental diseases.
ContributorsHalcomb, Michael Jordan (Author) / Chen, Qiang (Thesis director) / Steele, Kelly (Committee member) / Barrett, The Honors College (Contributor) / College of Letters and Sciences (Contributor)
Created2015-05
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Description
Forensic science is the application of science to matters of law, especially criminal investigation and procedure.​ ForenSICK Science​, on the other hand, is an educational YouTube channel. It was created in early 2019 after listening to two people on a podcast confidently preach surprisingly inaccurate information about forensic science. My

Forensic science is the application of science to matters of law, especially criminal investigation and procedure.​ ForenSICK Science​, on the other hand, is an educational YouTube channel. It was created in early 2019 after listening to two people on a podcast confidently preach surprisingly inaccurate information about forensic science. My goal in the creation of the channel was to give people the proper information regarding the practice. This goal grew to encompass several different fields including continued education practices, informal and nonformal learning, and combating “science speak.” Using YouTube as a tool in this journey was the first step in combating forensic inaccuracies.
Created2020-05
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Description
The process of communicating science between the general public and scientific community has been marked by several challenges in the modern setting. Namely, scientists’ trepidation toward misinterpretation, jeopardization of professional reputability, and perception of two distinct arenas of communication has led to the perpetuation of the deficit model of communication.

The process of communicating science between the general public and scientific community has been marked by several challenges in the modern setting. Namely, scientists’ trepidation toward misinterpretation, jeopardization of professional reputability, and perception of two distinct arenas of communication has led to the perpetuation of the deficit model of communication. This model is exceptionally limiting as it effectively removes the scientists from the public sphere and can have devastating societal repercussions. The dialogue model of communication is a much more effective communicative model for the modern setting but has been met with resistance in its adoption. As communication as a whole is grounded in multiple foundational disciplines of psychology, philosophy, linguistics, and other fields, it would be apparent that the adoption of the principles of polymathy would serve to better prepare scientists to engage in mass communication with the public. As polymathy is a lifelong pursuit, the implementation of narrative training into collegiate undergraduate science curriculum would serve as a particularly potent beginning. That is, narrative's ability to reach near-universal audiences, enhance the recall and comprehension of complex subject matter, and forge an empathetic connection essential to effective communication is uniquely suited in ensuring a more effective communicative dynamic between the scientific community and the general public. As such, this thesis serves to advocate the adoption of narrative-based communicative training into undergraduate science curriculum not as separate courses, but rather as direct incorporation. This would serve to both revitalize polymathy in the modern age and prepare the next generation of scientists to be better equipped for the public dialogue.
ContributorsCoker, Keaton M (Author) / Ramsey, Ramsey E. (Thesis director) / Wentzel, Bonnie (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
The use of DNA testing has been focused primarily on biological samples such as blood or saliva found at crime scenes. These types of evidence in the forensic field are sometimes difficult to come by, especially when there is no body to find to verify things such as identity or

The use of DNA testing has been focused primarily on biological samples such as blood or saliva found at crime scenes. These types of evidence in the forensic field are sometimes difficult to come by, especially when there is no body to find to verify things such as identity or status of a person. In the case of the burial of a body, they can be remote and relocated multiple times depending on each situation. Clandestine burials are not uncommon especially in the Arizona desert by the United States and Mexico border. Since there is no physical body to find the next best avenue to finding a clandestine burial is through search teams which can take weeks to months or other expensive technology such as ground penetrating radar (GPR). A new more interesting avenue to search for bodies is using the most found material–soil. Technology has allowed the possibility of using soil DNA microbiome testing initially to study the varieties of microbes that compose in soil. Microbiomes are unique and plentiful and essentially inescapable as humans are hosts of millions of them. The idea of a microbiome footprint at a crime scene seems out of reach considering the millions of species that can be found in various areas. Yet it is not impossible to get a list of varieties of species that could indicate there was a body in the soil as microbiomes seep through from decomposition. This study determines the viability of using soil microbial DNA as a method of locating clandestine graves by testing 6 different locations of a previous pig decomposition simulation. These two locations give two different scenarios that a body may be found either exposed to the sun in an open field or hidden under foliage such as a tree in the Sonoran Desert. The experiment will also determine more factors that could contribute to a correlation of microbiome specific groups associated with decomposition in soil such as firmicutes. The use of soil microbial DNA testing could open the doors to more interpretation of information to eventually be on par with the forensic use of biological DNA testing which could potentially supplement testimonies on assumed burial locations that occurs frequently in criminal cases of body relocation and reburial.
ContributorsMata Salinas, Jennifer (Author) / Marshall, Pamela (Thesis director) / Bolhofner , Katelyn (Committee member) / Wang, Yue (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2022-05
Description
My Honors Thesis/ Creative Project was an collection of art pieces that were based on a research done at West Campus in Dr. Weidner's forensic entomology laboratory. In this research, two swine carcasses were place outdoors for 21 days during the four seasons. The goal was to collect insects that

My Honors Thesis/ Creative Project was an collection of art pieces that were based on a research done at West Campus in Dr. Weidner's forensic entomology laboratory. In this research, two swine carcasses were place outdoors for 21 days during the four seasons. The goal was to collect insects that approached and colonized the carcasses. The collected data can be used to determine the TOC (time of colonization) of some insects; thus, it can help to calculate the PMI (postmortem interval). Different collection were used like larvae rearing, pitfalls, netting, and hand collection. The larvae were reared into adulthood and then identified into a species. The rest of the insects were identified into orders. To present this information, the data collected from the two carcasses was combined to make the presentation easier to understand. I created four circular canvases to present the collection of flies in each check. It shows both flies were reared and which were seen or collected. The other series of work that I sculpted were 120 ceramics flowers to represent the insects orders that were observed in each season and check. During my thesis defense, I presented the research project, and how my project can help people understand this research.
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12
ContributorsMunoz Zavala, Jaira (Author) / Weidner, Lauren (Thesis director) / Meeds, Andrew (Committee member) / Neubauer, Mary (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Art (Contributor)
Created2023-12