Matching Items (162)
Filtering by

Clear all filters

135335-Thumbnail Image.png
Description
Memory CD8+ T-cells can persist in the absence of antigen, primed for immediate activation and proliferation if later exposed to the same antigen. These cytotoxic lymphocytes provide long-term immunity following an acute infection. Studies have observed that intermediate levels of general T cell transfer prior to infection may cause an

Memory CD8+ T-cells can persist in the absence of antigen, primed for immediate activation and proliferation if later exposed to the same antigen. These cytotoxic lymphocytes provide long-term immunity following an acute infection. Studies have observed that intermediate levels of general T cell transfer prior to infection may cause an inappropriate response resulting in increased pathology rather than prevention. Therefore, our study focused on a memory CD8 T-cell therapy using lymphocytic choriomeningitis virus (LCMV) specific splenocytes, which activate and proliferate at an accelerated pace compared to that of naive T-cells. LCMV is a natural murine pathogen which also poses a zoonotic infection threat to humans, and the effect of immune cell vaccination therapies for LCMV is not fully understood. We observed the effect of multiple memory CD8 T cell dosage levels on overall disease and memory CD8 T-cell response to the virus. Infection by exposure to a carrier was shown to have a reduced impact on mice receiving higher doses of memory T cells prior to infection compared to mice receiving less or no memory cells. Higher presence of activated memory cells were shown to correlate with less disease-related weight loss and accelerated recovery times. Survival rate after exposure to carriers was not shown to be affected by dosage level, warranting further research regarding the prevalence of the immunopathology observed in other studies in natural murine transmission models.
ContributorsMiller, Charles (Author) / Blattman, Joseph (Thesis director) / Holechek, Susan (Committee member) / Carmen, Joshua (Committee member) / W. P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsTaut, Sarah (Author) / Mullins, Hunter (Co-author) / Huang, Hai (Co-author) / Lam, Jadon (Co-author) / Lee, Youngju (Co-author) / Goode, Zachary (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsLam, Jadon (Author) / Mullins, Hunter (Co-author) / Huang, Hai (Co-author) / Taut, Sarah (Co-author) / Lee, Youngju (Co-author) / Goode, Zachary (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor) / Human Systems Engineering (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsMullins, Hunter (Author) / Lam, Jadon (Co-author) / Goode, Zachary (Co-author) / Taut, Sarah (Co-author) / Lee, Youngju (Co-author) / Huang, Hai (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsLee, Youngju (Author) / Taut, Sarah (Co-author) / Goode, Zachary (Co-author) / Lam, Jadon (Co-author) / Huang, Hai (Co-author) / Mullins, Hunter (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Management and Entrepreneurship (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsGoode, Zachary (Author) / Huang, Hai (Co-author) / Lam, Jadon (Co-author) / Lee, Youngju (Co-author) / Taut, Sarah (Co-author) / Mullins, Hunter (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor) / School of Manufacturing Systems and Networks (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsHuang, Hai (Author) / Mullins, Hunter (Co-author) / Lam, Jadon (Co-author) / Taut, Sarah (Co-author) / Goode, Zachary (Co-author) / Lee, Youngju (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor) / Department of Supply Chain Management (Contributor)
Created2023-05
Description

Chameleons are notoriously a difficult species to provide proper husbandry for in captivity. They are an extremely intriguing species that has been gaining popularity among HERP enthusiasts, but the difficulty of care is deterring owners from these wonderful creatures. Building a proper enclosure takes a lot of time to plan

Chameleons are notoriously a difficult species to provide proper husbandry for in captivity. They are an extremely intriguing species that has been gaining popularity among HERP enthusiasts, but the difficulty of care is deterring owners from these wonderful creatures. Building a proper enclosure takes a lot of time to plan and research. Then to gather all the different supplies and to build the enclosure takes even longer. New or inexperienced chameleon owners tend to build improper enclosures, and this can be detrimental to a chameleon's health. My small business provides an online service that allows a building experience custom to my clients’ new friend’s needs.

ContributorsLagasse, Samantha (Author) / Byrne, Jared (Thesis director) / Baleen, Rachel (Committee member) / Yang, Andrea (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

Through Founders Lab, our group ideated an innovative new way for people to track their health and wellness. The app uses a 4-part circle system where users track their everyday progress in the following areas: diet, exercise, development, and mental wellness. Users can form groups with friends and family members

Through Founders Lab, our group ideated an innovative new way for people to track their health and wellness. The app uses a 4-part circle system where users track their everyday progress in the following areas: diet, exercise, development, and mental wellness. Users can form groups with friends and family members to provide support to one another. Through tracking their daily activities, users can earn tokens which are redeemable for relevant discounts. The app also hosts a variety of ways for users to be recognized for their healthy routine such as challenge trophies, activity history, and other social features. Overall, Circle Up aims to improve the daily routines of individuals to propel them into a healthier lifestyle.

ContributorsHeinrich, Miranda (Author) / Cech, Derek (Co-author) / Aronoff, Annette (Co-author) / Sliwa, Haley (Co-author) / Rozelle, Reed (Co-author) / Byrne, Jared (Thesis director) / Larson, Wiley (Committee member) / Zock, Christopher (Committee member) / Barrett, The Honors College (Contributor) / Department of Supply Chain Management (Contributor) / School of Art (Contributor)
Created2023-05
184056-Thumbnail Image.png
Description

Our Founders Lab group created a pop-up thrift store on campus using donated clothing. We generated over $1000 in profits from our clothing sales to donate to a local charity, making our team the highest earning Founders Lab team. Our shop, Devils Rack, tabled twice on the Tempe ASU campus

Our Founders Lab group created a pop-up thrift store on campus using donated clothing. We generated over $1000 in profits from our clothing sales to donate to a local charity, making our team the highest earning Founders Lab team. Our shop, Devils Rack, tabled twice on the Tempe ASU campus in order to generate our revenue.

ContributorsHaffner, Amanda (Author) / Walsh, Elizabeth (Co-author) / Soble, Lena (Co-author) / Burton, Tanner (Co-author) / Steffes, Keelyn (Co-author) / Byrne, Jared (Thesis director) / Lee, Christopher (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Department of Information Systems (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05