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- Creators: Yang, Yezhou
Description
Handwritten documents have gained popularity in various domains including education and business. A key task in analyzing a complex document is to distinguish between various content types such as text, math, graphics, tables and so on. For example, one such aspect could be a region on the document with a mathematical expression; in this case, the label would be math. This differentiation facilitates the performance of specific recognition tasks depending on the content type. We hypothesize that the recognition accuracy of the subsequent tasks such as textual, math, and shape recognition will increase, further leading to a better analysis of the document.
Content detection on handwritten documents assigns a particular class to a homogeneous portion of the document. To complete this task, a set of handwritten solutions was digitally collected from middle school students located in two different geographical regions in 2017 and 2018. This research discusses the methods to collect, pre-process and detect content type in the collected handwritten documents. A total of 4049 documents were extracted in the form of image, and json format; and were labelled using an object labelling software with tags being text, math, diagram, cross out, table, graph, tick mark, arrow, and doodle. The labelled images were fed to the Tensorflow’s object detection API to learn a neural network model. We show our results from two neural networks models, Faster Region-based Convolutional Neural Network (Faster R-CNN) and Single Shot detection model (SSD).
Content detection on handwritten documents assigns a particular class to a homogeneous portion of the document. To complete this task, a set of handwritten solutions was digitally collected from middle school students located in two different geographical regions in 2017 and 2018. This research discusses the methods to collect, pre-process and detect content type in the collected handwritten documents. A total of 4049 documents were extracted in the form of image, and json format; and were labelled using an object labelling software with tags being text, math, diagram, cross out, table, graph, tick mark, arrow, and doodle. The labelled images were fed to the Tensorflow’s object detection API to learn a neural network model. We show our results from two neural networks models, Faster Region-based Convolutional Neural Network (Faster R-CNN) and Single Shot detection model (SSD).
ContributorsFaizaan, Shaik Mohammed (Author) / VanLehn, Kurt (Thesis advisor) / Cheema, Salman Shaukat (Thesis advisor) / Yang, Yezhou (Committee member) / Arizona State University (Publisher)
Created2018
Description
Rapid intraoperative diagnosis of brain tumors is of great importance for planning treatment and guiding the surgeon about the extent of resection. Currently, the standard for the preliminary intraoperative tissue analysis is frozen section biopsy that has major limitations such as tissue freezing and cutting artifacts, sampling errors, lack of immediate interaction between the pathologist and the surgeon, and time consuming.
Handheld, portable confocal laser endomicroscopy (CLE) is being explored in neurosurgery for its ability to image histopathological features of tissue at cellular resolution in real time during brain tumor surgery. Over the course of examination of the surgical tumor resection, hundreds to thousands of images may be collected. The high number of images requires significant time and storage load for subsequent reviewing, which motivated several research groups to employ deep convolutional neural networks (DCNNs) to improve its utility during surgery. DCNNs have proven to be useful in natural and medical image analysis tasks such as classification, object detection, and image segmentation.
This thesis proposes using DCNNs for analyzing CLE images of brain tumors. Particularly, it explores the practicality of DCNNs in three main tasks. First, off-the shelf DCNNs were used to classify images into diagnostic and non-diagnostic. Further experiments showed that both ensemble modeling and transfer learning improved the classifier’s accuracy in evaluating the diagnostic quality of new images at test stage. Second, a weakly-supervised learning pipeline was developed for localizing key features of diagnostic CLE images from gliomas. Third, image style transfer was used to improve the diagnostic quality of CLE images from glioma tumors by transforming the histology patterns in CLE images of fluorescein sodium-stained tissue into the ones in conventional hematoxylin and eosin-stained tissue slides.
These studies suggest that DCNNs are opted for analysis of CLE images. They may assist surgeons in sorting out the non-diagnostic images, highlighting the key regions and enhancing their appearance through pattern transformation in real time. With recent advances in deep learning such as generative adversarial networks and semi-supervised learning, new research directions need to be followed to discover more promises of DCNNs in CLE image analysis.
Handheld, portable confocal laser endomicroscopy (CLE) is being explored in neurosurgery for its ability to image histopathological features of tissue at cellular resolution in real time during brain tumor surgery. Over the course of examination of the surgical tumor resection, hundreds to thousands of images may be collected. The high number of images requires significant time and storage load for subsequent reviewing, which motivated several research groups to employ deep convolutional neural networks (DCNNs) to improve its utility during surgery. DCNNs have proven to be useful in natural and medical image analysis tasks such as classification, object detection, and image segmentation.
This thesis proposes using DCNNs for analyzing CLE images of brain tumors. Particularly, it explores the practicality of DCNNs in three main tasks. First, off-the shelf DCNNs were used to classify images into diagnostic and non-diagnostic. Further experiments showed that both ensemble modeling and transfer learning improved the classifier’s accuracy in evaluating the diagnostic quality of new images at test stage. Second, a weakly-supervised learning pipeline was developed for localizing key features of diagnostic CLE images from gliomas. Third, image style transfer was used to improve the diagnostic quality of CLE images from glioma tumors by transforming the histology patterns in CLE images of fluorescein sodium-stained tissue into the ones in conventional hematoxylin and eosin-stained tissue slides.
These studies suggest that DCNNs are opted for analysis of CLE images. They may assist surgeons in sorting out the non-diagnostic images, highlighting the key regions and enhancing their appearance through pattern transformation in real time. With recent advances in deep learning such as generative adversarial networks and semi-supervised learning, new research directions need to be followed to discover more promises of DCNNs in CLE image analysis.
ContributorsIzady Yazdanabadi, Mohammadhassan (Author) / Preul, Mark (Thesis advisor) / Yang, Yezhou (Thesis advisor) / Nakaji, Peter (Committee member) / Vernon, Brent (Committee member) / Arizona State University (Publisher)
Created2019