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This dissertation presents methods for addressing research problems that currently can only adequately be solved using Quality Reliability Engineering (QRE) approaches especially accelerated life testing (ALT) of electronic printed wiring boards with applications to avionics circuit boards. The methods presented in this research are generally applicable to circuit boards, but

This dissertation presents methods for addressing research problems that currently can only adequately be solved using Quality Reliability Engineering (QRE) approaches especially accelerated life testing (ALT) of electronic printed wiring boards with applications to avionics circuit boards. The methods presented in this research are generally applicable to circuit boards, but the data generated and their analysis is for high performance avionics. Avionics equipment typically requires 20 years expected life by aircraft equipment manufacturers and therefore ALT is the only practical way of performing life test estimates. Both thermal and vibration ALT induced failure are performed and analyzed to resolve industry questions relating to the introduction of lead-free solder product and processes into high reliability avionics. In chapter 2, thermal ALT using an industry standard failure machine implementing Interconnect Stress Test (IST) that simulates circuit board life data is compared to real production failure data by likelihood ratio tests to arrive at a mechanical theory. This mechanical theory results in a statistically equivalent energy bound such that failure distributions below a specific energy level are considered to be from the same distribution thus allowing testers to quantify parameter setting in IST prior to life testing. In chapter 3, vibration ALT comparing tin-lead and lead-free circuit board solder designs involves the use of the likelihood ratio (LR) test to assess both complete failure data and S-N curves to present methods for analyzing data. Failure data is analyzed using Regression and two-way analysis of variance (ANOVA) and reconciled with the LR test results that indicating that a costly aging pre-process may be eliminated in certain cases. In chapter 4, vibration ALT for side-by-side tin-lead and lead-free solder black box designs are life tested. Commercial models from strain data do not exist at the low levels associated with life testing and need to be developed because testing performed and presented here indicate that both tin-lead and lead-free solders are similar. In addition, earlier failures due to vibration like connector failure modes will occur before solder interconnect failures.
ContributorsJuarez, Joseph Moses (Author) / Montgomery, Douglas C. (Thesis advisor) / Borror, Connie M. (Thesis advisor) / Gel, Esma (Committee member) / Mignolet, Marc (Committee member) / Pan, Rong (Committee member) / Arizona State University (Publisher)
Created2012
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Description
In mixture-process variable experiments, it is common that the number of runs is greater than in mixture-only or process-variable experiments. These experiments have to estimate the parameters from the mixture components, process variables, and interactions of both variables. In some of these experiments there are variables that are hard to

In mixture-process variable experiments, it is common that the number of runs is greater than in mixture-only or process-variable experiments. These experiments have to estimate the parameters from the mixture components, process variables, and interactions of both variables. In some of these experiments there are variables that are hard to change or cannot be controlled under normal operating conditions. These situations often prohibit a complete randomization for the experimental runs due to practical and economical considerations. Furthermore, the process variables can be categorized into two types: variables that are controllable and directly affect the response, and variables that are uncontrollable and primarily affect the variability of the response. These uncontrollable variables are called noise factors and assumed controllable in a laboratory environment for the purpose of conducting experiments. The model containing both noise variables and control factors can be used to determine factor settings for the control factor that makes the response "robust" to the variability transmitted from the noise factors. These types of experiments can be analyzed in a model for the mean response and a model for the slope of the response within a split-plot structure. When considering the experimental designs, low prediction variances for the mean and slope model are desirable. The methods for the mixture-process variable designs with noise variables considering a restricted randomization are demonstrated and some mixture-process variable designs that are robust to the coefficients of interaction with noise variables are evaluated using fraction design space plots with the respect to the prediction variance properties. Finally, the G-optimal design that minimizes the maximum prediction variance over the entire design region is created using a genetic algorithm.
ContributorsCho, Tae Yeon (Author) / Montgomery, Douglas C. (Thesis advisor) / Borror, Connie M. (Thesis advisor) / Shunk, Dan L. (Committee member) / Gel, Esma S (Committee member) / Kulahci, Murat (Committee member) / Arizona State University (Publisher)
Created2010
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Description
Uncertainty Quantification (UQ) is crucial in assessing the reliability of predictivemodels that make decisions for human experts in a data-rich world. The Bayesian approach to UQ for inverse problems has gained popularity. However, addressing UQ in high-dimensional inverse problems is challenging due to the intensity and inefficiency of Markov Chain

Uncertainty Quantification (UQ) is crucial in assessing the reliability of predictivemodels that make decisions for human experts in a data-rich world. The Bayesian approach to UQ for inverse problems has gained popularity. However, addressing UQ in high-dimensional inverse problems is challenging due to the intensity and inefficiency of Markov Chain Monte Carlo (MCMC) based Bayesian inference methods. Consequently, the first primary focus of this thesis is enhancing efficiency and scalability for UQ in inverse problems. On the other hand, the omnipresence of spatiotemporal data, particularly in areas like traffic analysis, underscores the need for effectively addressing inverse problems with spatiotemporal observations. Conventional solutions often overlook spatial or temporal correlations, resulting in underutilization of spatiotemporal interactions for parameter learning. Appropriately modeling spatiotemporal observations in inverse problems thus forms another pivotal research avenue. In terms of UQ methodologies, the calibration-emulation-sampling (CES) scheme has emerged as effective for large-dimensional problems. I introduce a novel CES approach by employing deep neural network (DNN) models during the emulation and sampling phase. This approach not only enhances computational efficiency but also diminishes sensitivity to training set variations. The newly devised “Dimension- Reduced Emulative Autoencoder Monte Carlo (DREAM)” algorithm scales Bayesian UQ up to thousands of dimensions in physics-constrained inverse problems. The algorithm’s effectiveness is exemplified through elliptic and advection-diffusion inverse problems. In the realm of spatiotemporal modeling, I propose to use Spatiotemporal Gaussian processes (STGP) in likelihood modeling and Spatiotemporal Besov processes (STBP) in prior modeling separately. These approaches highlight the efficacy of incorporat- ing spatial and temporal information for enhanced parameter estimation and UQ. Additionally, the superiority of STGP is demonstrated compared to static and time- averaged methods in time-dependent advection-diffusion partial differential equation (PDE) and three chaotic ordinary differential equations (ODE). Expanding upon Besov Process (BP), a method known for sparsity-promotion and edge-preservation, STBP is introduced to capture spatial data features and model temporal correlations by replacing the random coefficients in the series expansion with stochastic time functions following Q-exponential process(Q-EP). This advantage is showcased in dynamic computerized tomography (CT) reconstructions through comparison with classic STGP and a time-uncorrelated approach.
ContributorsLi, Shuyi (Author) / Lan, Shiwei (Thesis advisor) / Hahn, Paul (Committee member) / McCulloch, Robert (Committee member) / Dan, Cheng (Committee member) / Lopes, Hedibert (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation centers on treatment effect estimation in the field of causal inference, and aims to expand the toolkit for effect estimation when the treatment variable is binary. Two new stochastic tree-ensemble methods for treatment effect estimation in the continuous outcome setting are presented. The Accelerated Bayesian Causal Forrest (XBCF)

This dissertation centers on treatment effect estimation in the field of causal inference, and aims to expand the toolkit for effect estimation when the treatment variable is binary. Two new stochastic tree-ensemble methods for treatment effect estimation in the continuous outcome setting are presented. The Accelerated Bayesian Causal Forrest (XBCF) model handles variance via a group-specific parameter, and the Heteroskedastic version of XBCF (H-XBCF) uses a separate tree ensemble to learn covariate-dependent variance. This work also contributes to the field of survival analysis by proposing a new framework for estimating survival probabilities via density regression. Within this framework, the Heteroskedastic Accelerated Bayesian Additive Regression Trees (H-XBART) model, which is also developed as part of this work, is utilized in treatment effect estimation for right-censored survival outcomes. All models have been implemented as part of the XBART R package, and their performance is evaluated via extensive simulation studies with appropriate sets of comparators. The contributed methods achieve similar levels of performance, while being orders of magnitude (sometimes as much as 100x) faster than comparator state-of-the-art methods, thus offering an exciting opportunity for treatment effect estimation in the large data setting.
ContributorsKrantsevich, Nikolay (Author) / Hahn, P Richard (Thesis advisor) / McCulloch, Robert (Committee member) / Zhou, Shuang (Committee member) / Lan, Shiwei (Committee member) / He, Jingyu (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Tracking disease cases is an essential task in public health; however, tracking the number of cases of a disease may be difficult not every infection can be recorded by public health authorities. Notably, this may happen with whole country measles case reports, even such countries with robust registration systems.

Tracking disease cases is an essential task in public health; however, tracking the number of cases of a disease may be difficult not every infection can be recorded by public health authorities. Notably, this may happen with whole country measles case reports, even such countries with robust registration systems. Eilertson et al. (2019) propose using a state-space model combined with maximum likelihood methods for estimating measles transmission. A Bayesian approach that uses particle Markov Chain Monte Carlo (pMCMC) is proposed to estimate the parameters of the non-linear state-space model developed in Eilertson et al. (2019) and similar previous studies. This dissertation illustrates the performance of this approach by calculating posterior estimates of the model parameters and predictions of the unobserved states in simulations and case studies. Also, Iteration Filtering (IF2) is used as a support method to verify the Bayesian estimation and to inform the selection of prior distributions. In the second half of the thesis, a birth-death process is proposed to model the unobserved population size of a disease vector. This model studies the effect of a disease vector population size on a second affected population. The second population follows a non-homogenous Poisson process when conditioned on the vector process with a transition rate given by a scaled version of the vector population. The observation model also measures a potential threshold event when the host species population size surpasses a certain level yielding a higher transmission rate. A maximum likelihood procedure is developed for this model, which combines particle filtering with the Minorize-Maximization (MM) algorithm and extends the work of Crawford et al. (2014).
ContributorsMartinez Rivera, Wilmer Osvaldo (Author) / Fricks, John (Thesis advisor) / Reiser, Mark (Committee member) / Zhou, Shuang (Committee member) / Cheng, Dan (Committee member) / Lan, Shiwei (Committee member) / Arizona State University (Publisher)
Created2022
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Description
This dissertation covers several topics in machine learning and causal inference. First, the question of “feature selection,” a common byproduct of regularized machine learning methods, is investigated theoretically in the context of treatment effect estimation. This involves a detailed review and extension of frameworks for estimating causal effects and in-depth

This dissertation covers several topics in machine learning and causal inference. First, the question of “feature selection,” a common byproduct of regularized machine learning methods, is investigated theoretically in the context of treatment effect estimation. This involves a detailed review and extension of frameworks for estimating causal effects and in-depth theoretical study. Next, various computational approaches to estimating causal effects with machine learning methods are compared with these theoretical desiderata in mind. Several improvements to current methods for causal machine learning are identified and compelling angles for further study are pinpointed. Finally, a common method used for “explaining” predictions of machine learning algorithms, SHAP, is evaluated critically through a statistical lens.
ContributorsHerren, Andrew (Author) / Hahn, P Richard (Thesis advisor) / Kao, Ming-Hung (Committee member) / Lopes, Hedibert (Committee member) / McCulloch, Robert (Committee member) / Zhou, Shuang (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation develops versatile modeling tools to estimate causal effects when conditional unconfoundedness is not immediately satisfied. Chapter 2 provides a brief overview ofcommon techniques in causal inference, with a focus on models relevant to the data explored in later chapters. The rest of the dissertation focuses on the development of

This dissertation develops versatile modeling tools to estimate causal effects when conditional unconfoundedness is not immediately satisfied. Chapter 2 provides a brief overview ofcommon techniques in causal inference, with a focus on models relevant to the data explored in later chapters. The rest of the dissertation focuses on the development of novel “reduced form” models which are designed to assess the particular challenges of different datasets. Chapter 3 explores the question of whether or not forecasts of bankruptcy cause bankruptcy. The question arises from the observation that companies issued going concern opinions were more likely to go bankrupt in the following year, leading people to speculate that the opinions themselves caused the bankruptcy via a “self-fulfilling prophecy”. A Bayesian machine learning sensitivity analysis is developed to answer this question. In exchange for additional flexibility and fewer assumptions, this approach loses point identification of causal effects and thus a sensitivity analysis is developed to study a wide range of plausible scenarios of the causal effect of going concern opinions on bankruptcy. Reported in the simulations are different performance metrics of the model in comparison with other popular methods and a robust analysis of the sensitivity of the model to mis-specification. Results on empirical data indicate that forecasts of bankruptcies likely do have a small causal effect. Chapter 4 studies the effects of vaccination on COVID-19 mortality at the state level in the United States. The dynamic nature of the pandemic complicates more straightforward regression adjustments and invalidates many alternative models. The chapter comments on the limitations of mechanistic approaches as well as traditional statistical methods to epidemiological data. Instead, a state space model is developed that allows the study of the ever-changing dynamics of the pandemic’s progression. In the first stage, the model decomposes the observed mortality data into component surges, and later uses this information in a semi-parametric regression model for causal analysis. Results are investigated thoroughly for empirical justification and stress-tested in simulated settings.
ContributorsPapakostas, Demetrios (Author) / Hahn, Paul (Thesis advisor) / McCulloch, Robert (Committee member) / Zhou, Shuang (Committee member) / Kao, Ming-Hung (Committee member) / Lan, Shiwei (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation centers on Bayesian Additive Regression Trees (BART) and Accelerated BART (XBART) and presents a series of models that tackle extrapolation, classification, and causal inference challenges. To improve extrapolation in tree-based models, I propose a method called local Gaussian Process (GP) that combines Gaussian process regression with trained BART

This dissertation centers on Bayesian Additive Regression Trees (BART) and Accelerated BART (XBART) and presents a series of models that tackle extrapolation, classification, and causal inference challenges. To improve extrapolation in tree-based models, I propose a method called local Gaussian Process (GP) that combines Gaussian process regression with trained BART trees. This allows for extrapolation based on the most relevant data points and covariate variables determined by the trees' structure. The local GP technique is extended to the Bayesian causal forest (BCF) models to address the positivity violation issue in causal inference. Additionally, I introduce the LongBet model to estimate time-varying, heterogeneous treatment effects in panel data. Furthermore, I present a Poisson-based model, with a modified likelihood for XBART for the multi-class classification problem.
ContributorsWang, Meijia (Author) / Hahn, Paul (Thesis advisor) / He, Jingyu (Committee member) / Lan, Shiwei (Committee member) / McCulloch, Robert (Committee member) / Zhou, Shuang (Committee member) / Arizona State University (Publisher)
Created2024
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Description
The primary objective in time series analysis is forecasting. Raw data often exhibits nonstationary behavior: trends, seasonal cycles, and heteroskedasticity. After data is transformed to a weakly stationary process, autoregressive moving average (ARMA) models may capture the remaining temporal dynamics to improve forecasting. Estimation of ARMA can be performed

The primary objective in time series analysis is forecasting. Raw data often exhibits nonstationary behavior: trends, seasonal cycles, and heteroskedasticity. After data is transformed to a weakly stationary process, autoregressive moving average (ARMA) models may capture the remaining temporal dynamics to improve forecasting. Estimation of ARMA can be performed through regressing current values on previous realizations and proxy innovations. The classic paradigm fails when dynamics are nonlinear; in this case, parametric, regime-switching specifications model changes in level, ARMA dynamics, and volatility, using a finite number of latent states. If the states can be identified using past endogenous or exogenous information, a threshold autoregressive (TAR) or logistic smooth transition autoregressive (LSTAR) model may simplify complex nonlinear associations to conditional weakly stationary processes. For ARMA, TAR, and STAR, order parameters quantify the extent past information is associated with the future. Unfortunately, even if model orders are known a priori, the possibility of over-fitting can lead to sub-optimal forecasting performance. By intentionally overestimating these orders, a linear representation of the full model is exploited and Bayesian regularization can be used to achieve sparsity. Global-local shrinkage priors for AR, MA, and exogenous coefficients are adopted to pull posterior means toward 0 without over-shrinking relevant effects. This dissertation introduces, evaluates, and compares Bayesian techniques that automatically perform model selection and coefficient estimation of ARMA, TAR, and STAR models. Multiple Monte Carlo experiments illustrate the accuracy of these methods in finding the "true" data generating process. Practical applications demonstrate their efficacy in forecasting.
ContributorsGiacomazzo, Mario (Author) / Kamarianakis, Yiannis (Thesis advisor) / Reiser, Mark R. (Committee member) / McCulloch, Robert (Committee member) / Hahn, Richard (Committee member) / Fricks, John (Committee member) / Arizona State University (Publisher)
Created2018
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Description
This dissertation investigates the classification of systemic lupus erythematosus (SLE) in the presence of non-SLE alternatives, while developing novel curve classification methodologies with wide ranging applications. Functional data representations of plasma thermogram measurements and the corresponding derivative curves provide predictors yet to be investigated for SLE identification. Functional

This dissertation investigates the classification of systemic lupus erythematosus (SLE) in the presence of non-SLE alternatives, while developing novel curve classification methodologies with wide ranging applications. Functional data representations of plasma thermogram measurements and the corresponding derivative curves provide predictors yet to be investigated for SLE identification. Functional nonparametric classifiers form a methodological basis, which is used herein to develop a) the family of ESFuNC segment-wise curve classification algorithms and b) per-pixel ensembles based on logistic regression and fused-LASSO. The proposed methods achieve test set accuracy rates as high as 94.3%, while returning information about regions of the temperature domain that are critical for population discrimination. The undertaken analyses suggest that derivate-based information contributes significantly in improved classification performance relative to recently published studies on SLE plasma thermograms.
ContributorsBuscaglia, Robert, Ph.D (Author) / Kamarianakis, Yiannis (Thesis advisor) / Armbruster, Dieter (Committee member) / Lanchier, Nicholas (Committee member) / McCulloch, Robert (Committee member) / Reiser, Mark R. (Committee member) / Arizona State University (Publisher)
Created2018