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This thesis presents a meta-analysis of lead-free solder reliability. The qualitative analyses of the failure modes of lead- free solder under different stress tests including drop test, bend test, thermal test and vibration test are discussed. The main cause of failure of lead- free solder is fatigue crack, and the

This thesis presents a meta-analysis of lead-free solder reliability. The qualitative analyses of the failure modes of lead- free solder under different stress tests including drop test, bend test, thermal test and vibration test are discussed. The main cause of failure of lead- free solder is fatigue crack, and the speed of propagation of the initial crack could differ from different test conditions and different solder materials. A quantitative analysis about the fatigue behavior of SAC lead-free solder under thermal preconditioning process is conducted. This thesis presents a method of making prediction of failure life of solder alloy by building a Weibull regression model. The failure life of solder on circuit board is assumed Weibull distributed. Different materials and test conditions could affect the distribution by changing the shape and scale parameters of Weibull distribution. The method is to model the regression of parameters with different test conditions as predictors based on Bayesian inference concepts. In the process of building regression models, prior distributions are generated according to the previous studies, and Markov Chain Monte Carlo (MCMC) is used under WinBUGS environment.
ContributorsXu, Xinyue (Author) / Pan, Rong (Thesis advisor) / Montgomery, Douglas C. (Committee member) / Wu, Teresa (Committee member) / Arizona State University (Publisher)
Created2014
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Anomaly is a deviation from the normal behavior of the system and anomaly detection techniques try to identify unusual instances based on deviation from the normal data. In this work, I propose a machine-learning algorithm, referred to as Artificial Contrasts, for anomaly detection in categorical data in which neither the

Anomaly is a deviation from the normal behavior of the system and anomaly detection techniques try to identify unusual instances based on deviation from the normal data. In this work, I propose a machine-learning algorithm, referred to as Artificial Contrasts, for anomaly detection in categorical data in which neither the dimension, the specific attributes involved, nor the form of the pattern is known a priori. I use RandomForest (RF) technique as an effective learner for artificial contrast. RF is a powerful algorithm that can handle relations of attributes in high dimensional data and detect anomalies while providing probability estimates for risk decisions.

I apply the model to two simulated data sets and one real data set. The model was able to detect anomalies with a very high accuracy. Finally, by comparing the proposed model with other models in the literature, I demonstrate superior performance of the proposed model.
ContributorsMousavi, Seyyedehnasim (Author) / Runger, George C. (Thesis advisor) / Wu, Teresa (Committee member) / Kim, Sunghoon (Committee member) / Arizona State University (Publisher)
Created2016
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Description
Distributed Renewable energy generators are now contributing a significant amount of energy into the energy grid. Consequently, reliability adequacy of such energy generators will depend on making accurate forecasts of energy produced by them. Power outputs of Solar PV systems depend on the stochastic variation of environmental factors (solar irradiance,

Distributed Renewable energy generators are now contributing a significant amount of energy into the energy grid. Consequently, reliability adequacy of such energy generators will depend on making accurate forecasts of energy produced by them. Power outputs of Solar PV systems depend on the stochastic variation of environmental factors (solar irradiance, ambient temperature & wind speed) and random mechanical failures/repairs. Monte Carlo Simulation which is typically used to model such problems becomes too computationally intensive leading to simplifying state-space assumptions. Multi-state models for power system reliability offer a higher flexibility in providing a description of system state evolution and an accurate representation of probability. In this study, Universal Generating Functions (UGF) were used to solve such combinatorial problems. 8 grid connected Solar PV systems were analyzed with a combined capacity of about 5MW located in a hot-dry climate (Arizona) and accuracy of 98% was achieved when validated with real-time data. An analytics framework is provided to grid operators and utilities to effectively forecast energy produced by distributed energy assets and in turn, develop strategies for effective Demand Response in times of increased share of renewable distributed energy assets in the grid. Second part of this thesis extends the environmental modelling approach to develop an aging test to be run in conjunction with an accelerated test of Solar PV modules. Accelerated Lifetime Testing procedures in the industry are used to determine the dominant failure modes which the product undergoes in the field, as well as predict the lifetime of the product. UV stressor is one of the ten stressors which a PV module undergoes in the field. UV exposure causes browning of modules leading to drop in Short Circuit Current. This thesis presents an environmental modelling approach for the hot-dry climate and extends it to develop an aging test methodology. This along with the accelerated tests would help achieve the goal of correlating field failures with accelerated tests and obtain acceleration factor. This knowledge would help predict PV module degradation in the field within 30% of the actual value and help in knowing the PV module lifetime accurately.
ContributorsKadloor, Nikhil (Author) / Kuitche, Joseph (Thesis advisor) / Pan, Rong (Thesis advisor) / Wu, Teresa (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Understanding customer preference is crucial for new product planning and marketing decisions. This thesis explores how historical data can be leveraged to understand and predict customer preference. This thesis presents a decision support framework that provides a holistic view on customer preference by following a two-phase procedure. Phase-1 uses cluster

Understanding customer preference is crucial for new product planning and marketing decisions. This thesis explores how historical data can be leveraged to understand and predict customer preference. This thesis presents a decision support framework that provides a holistic view on customer preference by following a two-phase procedure. Phase-1 uses cluster analysis to create product profiles based on which customer profiles are derived. Phase-2 then delves deep into each of the customer profiles and investigates causality behind their preference using Bayesian networks. This thesis illustrates the working of the framework using the case of Intel Corporation, world’s largest semiconductor manufacturing company.
ContributorsRam, Sudarshan Venkat (Author) / Kempf, Karl G. (Thesis advisor) / Wu, Teresa (Thesis advisor) / Ju, Feng (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Nonalcoholic Steatohepatitis (NASH) is a severe form of Nonalcoholic fatty liverdisease, that is caused due to excessive calorie intake, sedentary lifestyle and in the absence of severe alcohol consumption. It is widely prevalent in the United States and in many other developed countries, affecting up to 25 percent of the population. Due to

Nonalcoholic Steatohepatitis (NASH) is a severe form of Nonalcoholic fatty liverdisease, that is caused due to excessive calorie intake, sedentary lifestyle and in the absence of severe alcohol consumption. It is widely prevalent in the United States and in many other developed countries, affecting up to 25 percent of the population. Due to being asymptotic, it usually goes unnoticed and may lead to liver failure if not treated at the right time. Currently, liver biopsy is the gold standard to diagnose NASH, but being an invasive procedure, it comes with it's own complications along with the inconvenience of sampling repeated measurements over a period of time. Hence, noninvasive procedures to assess NASH are urgently required. Magnetic Resonance Elastography (MRE) based Shear Stiffness and Loss Modulus along with Magnetic Resonance Imaging based proton density fat fraction have been successfully combined to predict NASH stages However, their role in the prediction of disease progression still remains to be investigated. This thesis thus looks into combining features from serial MRE observations to develop statistical models to predict NASH progression. It utilizes data from an experiment conducted on male mice to develop progressive and regressive NASH and trains ordinal models, ordered probit regression and ordinal forest on labels generated from a logistic regression model. The models are assessed on histological data collected at the end point of the experiment. The models developed provide a framework to utilize a non-invasive tool to predict NASH disease progression.
ContributorsDeshpande, Eeshan (Author) / Ju, Feng (Thesis advisor) / Wu, Teresa (Committee member) / Yan, Hao (Committee member) / Arizona State University (Publisher)
Created2021
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Description
With the increased demand for genetically modified T-cells in treating hematological malignancies, the need for an optimized measurement policy within the current good manufacturing practices for better quality control has grown greatly. There are several steps involved in manufacturing gene therapy. These steps are for the autologous-type gene therapy, in

With the increased demand for genetically modified T-cells in treating hematological malignancies, the need for an optimized measurement policy within the current good manufacturing practices for better quality control has grown greatly. There are several steps involved in manufacturing gene therapy. These steps are for the autologous-type gene therapy, in chronological order, are harvesting T-cells from the patient, activation of the cells (thawing the cryogenically frozen cells after transport to manufacturing center), viral vector transduction, Chimeric Antigen Receptor (CAR) attachment during T-cell expansion, then infusion into patient. The need for improved measurement heuristics within the transduction and expansion portions of the manufacturing process has reached an all-time high because of the costly nature of manufacturing the product, the high cycle time (approximately 14-28 days from activation to infusion), and the risk for external contamination during manufacturing that negatively impacts patients post infusion (such as illness and death).

The main objective of this work is to investigate and improve measurement policies on the basis of quality control in the transduction/expansion bio-manufacturing processes. More specifically, this study addresses the issue of measuring yield within the transduction/expansion phases of gene therapy. To do so, it was decided to model the process as a Markov Decision Process where the decisions being made are optimally chosen to create an overall optimal measurement policy; for a set of predefined parameters.
ContributorsStarkey, Michaela (Author) / Pedrielli, Giulia (Thesis advisor) / Li, Jing (Committee member) / Wu, Teresa (Committee member) / Arizona State University (Publisher)
Created2020
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Description
The COVID-19 outbreak that started in 2020, brought the world to its knees and is still a menace after three years. Over eighty-five million cases and over a million deaths have occurred due to COVID-19 during that time in the United States alone. A great deal of research has gone

The COVID-19 outbreak that started in 2020, brought the world to its knees and is still a menace after three years. Over eighty-five million cases and over a million deaths have occurred due to COVID-19 during that time in the United States alone. A great deal of research has gone into making epidemic models to show the impact of the virus by plotting the cases, deaths, and hospitalization due to COVID-19. However, there is very less research that has anything to do with mapping different variants of COVID-19. SARS-CoV-2, the virus that causes COVID-19, constantly mutates and multiple variants have emerged over time. The major variants include Beta, Gamma, Delta and the recent one, Omicron. The purpose of the research done in this thesis is to modify one of the epidemic models i.e., the Spatially Informed Rapid Testing for Epidemic Model (SIRTEM), in such a way that various variants of the virus will be modelled at the same time. The model will be assessed by adding the Omicron and the Delta variants and in doing so, the effects of different variants can be studied by looking at the positive cases, hospitalizations, and deaths from both the variants for the Arizona Population. The focus will be to find the best infection rate and testing rate by using Random numbers so that the published positive cases and the positive cases derived from the model have the least mean square error.
ContributorsVarghese, Allen Moncey (Author) / Pedrielli, Giulia (Thesis advisor) / Candan, Kasim S (Committee member) / Wu, Teresa (Committee member) / Arizona State University (Publisher)
Created2022