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Description
Human perceptual dimensions of sound are not necessarily simple representations of the actual physical dimensions that make up sensory input. In particular, research on the perception of interactions between acoustic frequency and intensity has shown that people exhibit a bias to expect the perception of pitch and loudness to change

Human perceptual dimensions of sound are not necessarily simple representations of the actual physical dimensions that make up sensory input. In particular, research on the perception of interactions between acoustic frequency and intensity has shown that people exhibit a bias to expect the perception of pitch and loudness to change together. Researchers have proposed that this perceptual bias occurs because sound sources tend to follow a natural regularity of a correlation between changes in intensity and frequency of sound. They postulate that the auditory system has adapted to expect this naturally occurring relationship to facilitate auditory scene analysis, the tracking and parsing sources of sound as listeners analyze their auditory environments. However, this correlation has only been tested with human speech and musical sounds. The current study explores if animal sounds also exhibit the same natural correlation between intensity and frequency and tests if people exhibit a perceptual bias to assume this correlation when listening to animal calls. Our principal hypotheses are that animal sounds will tend to exhibit a positive correlation between intensity and frequency and that, when hearing such sounds change in intensity, listeners will perceive them to also change in frequency and vice versa. Our tests with 21 animal calls and 8 control stimuli along with our experiment with participants responding to these stimuli supported these hypotheses. This research provides a further example of coupling of perceptual biases with natural regularities in the auditory domain, and provides a framework for understanding perceptual biases as functional adaptations that help perceivers more accurately anticipate and utilize reliable natural patterns to enhance scene analyses in real world environments.
ContributorsWilkinson, Zachary David (Author) / McBeath, Michael (Thesis director) / Glenberg, Arthur (Committee member) / Rutowski, Ronald (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2014-05
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Description
Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with DRSP, the impact of DRSP on cognition, especially in reference

Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with DRSP, the impact of DRSP on cognition, especially in reference to learning and memory, is not well understood. However, it is imperative to fully understand the cognitive effects of DRSP, both alone and in combination with EE (as taken in a combined oral contraceptive [COC]), so that women and their physicians can make a fully-informed decision when deciding to take a DRSP-containing COC. Study 1 examined the effects of three doses of DRSP in order to determine the optimal dose for combining with EE, and found that the medium dose of DRSP (30 µg/day) enhanced spatial working memory performance. In Study 2, the medium dose of DRSP from Study 1 was combined with low (0.125 µg/day) and high (0.3 µg/day) doses of EE to examine the effects of DRSP as taken with EE in a COC. The results from Study 2 indicated that when DRSP was combined with a low, but not high, dose of EE, spatial working memory impairments were seen at the highest working memory load. Anxiety-like behavior was evaluated using the OFT, and DRSP was shown to decrease measures of anxiety-like behavior. Additionally, while treatment with a high dose of EE decreased several measures of anxiety-like behavior, a low dose of EE did not, suggestive of a dose response. Taken together, the findings presented from both studies suggest that some of the cognitive effects of the combination of DRSP with EE are different than those of either hormone administered on its own. Further exploration in a preclinical, ovary-intact animal model is a next step to fully understand these effects in the translational context of a contraceptive, given that women taking an EE-DRSP combination are typically ovary-intact.
ContributorsPoisson, Mallori Louise (Author) / Bimonte-Nelson, Heather (Thesis director) / Doane, Leah (Committee member) / School of Nutrition and Health Promotion (Contributor) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
The degree to which adolescents describe themselves as gender typical, as defined by their interests, activities, personal qualities, and other characteristics, is related to a broad range of adjustment indices. The goal of this thesis was to review studies conducted between 2000 and 2017 to provide a summary and critique

The degree to which adolescents describe themselves as gender typical, as defined by their interests, activities, personal qualities, and other characteristics, is related to a broad range of adjustment indices. The goal of this thesis was to review studies conducted between 2000 and 2017 to provide a summary and critique of this research. A total of 18 studies were reviewed. The majority of findings indicate a positive association between gender typicality and beneficial adjustment outcomes, and a negative association between gender typicality and poor adjustment outcomes. Suggestions for future research and clinical implications of these findings are discussed.
ContributorsCohen, Alexandra Danielle (Author) / Updegraff, Kimberly (Thesis director) / Miller, Cindy (Committee member) / College of Integrative Sciences and Arts (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
The aim of this study was to determine whether IUD administration, with and without the presence of Levo, and with and without the presence of the ovaries, impacts cognition in a rat model. Rats received either Sham or Ovariectomy (Ovx) surgery (removal of the ovaries), plus either no IUD, a

The aim of this study was to determine whether IUD administration, with and without the presence of Levo, and with and without the presence of the ovaries, impacts cognition in a rat model. Rats received either Sham or Ovariectomy (Ovx) surgery (removal of the ovaries), plus either no IUD, a Blank IUD (without Levo), or a Levo-releasing IUD (Levo IUD), enabling us to evaluate the effects of Ovx and the effects of IUD administration on cognition. Two weeks after surgery, all treatment groups were tested on the water radial arm maze, Morris water maze, and visible platform task to evaluate cognition. At sacrifice, upon investigation of the uteri, it was determined that some of the IUDs were no longer present in animals from these groups: Sham\u2014Blank IUD, Ovx\u2014Blank IUD, and Sham\u2014Levo IUD. Results from the remaining three groups showed that compared to Sham animals with no IUDs, Ovx animals with no IUDs had marginally impaired working memory performance, and that Ovx animals with Levo IUDs as compared to Ovx animals with no IUDs had marginally enhanced memory performance, not specific to a particular memory type. Results also showed that Ovx animals with Levo IUDs had qualitatively more cells in their vaginal smears and increased uterine horn weight compared to Ovx animals with no IUDs, suggesting local stimulation of the Levo IUDs to the uterine horns. Overall, these results provide alternative evidence to the hypothesis that the Levo IUD administers Levo in solely a localized manner, and suggests that the possibility for the Levo IUD to affect reproductive cyclicity in ovary-intact animals is not rejected. The potential for the Levo IUD to exert effects on cognition suggests that either the hormone does in fact systemically circulate, or that the Levo IUD administration affects cognition by altering an as yet undetermined hormonal or other feedback between the uterus and the brain.
ContributorsStrouse, Isabel Martha (Author) / Bimonte-Nelson, Heather (Thesis director) / Glenberg, Arthur (Committee member) / Sirianni, Rachael (Committee member) / Conrad, Cheryl (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Description
Cultural beliefs and behaviors can serve as both risk and protective processes for Latino adolescents, with some recent empirical work suggesting the important protective role of bicultural values (e.g., endorsing high levels of both mainstream culture and culture of origin). We expanded on past research to explore whether bicultural values

Cultural beliefs and behaviors can serve as both risk and protective processes for Latino adolescents, with some recent empirical work suggesting the important protective role of bicultural values (e.g., endorsing high levels of both mainstream culture and culture of origin). We expanded on past research to explore whether bicultural values were associated with internalizing (depressive, anxiety, stress) symptoms and externalizing (alcohol use) symptoms among a sample of Latino adolescents preparing to begin college. We hypothesized biculturalism to protect against all negative outcomes. Our sample consisted of 209 college-bound Latino adolescents (65% female; 85.1% Mexican descent; 10.6% 1st generation, 62% 2nd generation) who were enrolled in university for the coming fall. All multivariate models included sex, ethnicity, parent education, and immigrant generation status as covariates. Correlations and multivariate analyses revealed that higher bicultural values were associated with lower depressive symptoms, lower anxiety symptoms, lower stress, and greater alcohol use. Gender was shown to moderate the relationship between biculturalism and alcohol use. Overall, findings suggested that greater bicultural values were associated with lower endorsement of internalizing symptoms for all participants, but higher endorsement of alcohol use over the last year for the highly bicultural females. Biculturalism may be particularly protective for Latino adolescents who are preparing to attend college given the need for them to transition into an environment with high acculturative demands. However, our results also highlight that these bicultural females may be at greater risk for alcohol use and related problems.
ContributorsDilgert, Janice (Author) / Doane, Leah (Thesis director) / Thompson, Daisy (Committee member) / Department of Psychology (Contributor) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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Description
The literature has consistently established levels of adolescent maladjustment well above national norms for both socioeconomic (SES) extremes (Lyman & Luthar 2014). Yet literature on positive adolescent adjustment, and its protective or even corrective factors is lacking (Eisenberg, Zhou, & Coller, 2001). This study examined the effects of gender and

The literature has consistently established levels of adolescent maladjustment well above national norms for both socioeconomic (SES) extremes (Lyman & Luthar 2014). Yet literature on positive adolescent adjustment, and its protective or even corrective factors is lacking (Eisenberg, Zhou, & Coller, 2001). This study examined the effects of gender and SES on parent attachment in relation to reports of prosocial behavior. Eleventh grade adolescents (N = 397) were recruited from two public high schools for academically-gifted students who were either high or low-level SES (i.e. the extremes). The students provided passive consent and answered questions on their demographics, perceived relationship with their parents, and tendency to behave in a prosocial manner. Multivariate analyses of variance and follow up analyses of variance were run by gender and SES to determine main effects for gender and SES on parent attachment and prosocial behavior. Regressions following preliminary correlations analyzed whether parental attachment predicted higher levels of adolescent prosocial behavior. Results demonstrated that females communicated with their mothers significantly more and reported higher levels of prosocial behavior than their male counterparts. Findings with regard to SES revealed that high SES adolescents reported increased parent attachment, whereas low SES adolescents reported higher levels of community\u2014based prosocial behaviors. Finally, certain dimensions of parent attachment predicted increases and decreases only in specific prosocial behaviors. Because prosocial behaviors change throughout adolescence, future ventures should consider a longitudinal analysis to obtain a more comprehensive picture of adolescent positive adjustment.
ContributorsAli, Hira (Author) / Luthar, Suniya (Thesis director) / Infurna, Frank (Committee member) / Davis, Mary (Committee member) / Department of Psychology (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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Description
Depression, anxiety, and suicidal thoughts or actions are on the rise in adolescents (National Institute of Mental Health, 2015; Bridge, Asti, & Horowitz, 2015). Parents, school administrators, and therapists are searching for resiliency factors with in at-risk groups to aid students in need. In previous work, Luthar and Zigler (1992)

Depression, anxiety, and suicidal thoughts or actions are on the rise in adolescents (National Institute of Mental Health, 2015; Bridge, Asti, & Horowitz, 2015). Parents, school administrators, and therapists are searching for resiliency factors with in at-risk groups to aid students in need. In previous work, Luthar and Zigler (1992) reported that intelligent youth are more resilient than less intelligent youth under low stress conditions but they lose their advantage under high stress conditions. This study examined whether intelligence (reflected in grade point average; GPA) and maladaptive (internalizing and externalizing symptoms) behaviors are negatively related in adolescents, and tested whether level of stress, reflected in emotion regulation and friendship quality, moderated that association. It also probed whether the relationships differ by gender. Sixth-graders (N=506) were recruited with active parental consent from three middle schools. Adolescents completed self-report questionnaires Regarding demo graphics, maladaptive behaviors, emotion regulation, and friendship quality, and GPA data were collected from the school. Regression analyses found that GPA was negatively related to externalizing symptoms. Girls with poor friendship communication report significantly higher maladaptive behaviors. This relation was more pronounced for girls with high GPAs, as predicted. Results support the theory that intelligent female adolescents are more reactive under adverse circumstances. Future efforts should follow students through middle school into high school to evaluate whether friendships remain important to adjustment, hold for boys as well as girls, and have implications for relationship interventions.
ContributorsGonzales, Ashlyn Carol (Author) / Luthar, Suniya (Thesis director) / Davis, Mary (Committee member) / Infurna, Frank (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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Description
Marijuana is currently the mostly widely used illicit drug in the U.S., and has been for multiple decades (Johnston et. al., 2016). Despite a growing belief that marijuana use is not harmful, over 4 million Americans have met criteria for marijuana use disorders in the past year alone (CBHSQ, 2015).

Marijuana is currently the mostly widely used illicit drug in the U.S., and has been for multiple decades (Johnston et. al., 2016). Despite a growing belief that marijuana use is not harmful, over 4 million Americans have met criteria for marijuana use disorders in the past year alone (CBHSQ, 2015). According to marijuana trajectory studies, about a third of marijuana users will end up quitting later in life, but some \u2014 such as those who meet criteria for dependence \u2014 have a much greater difficultly quitting. Therefore, by looking at marijuana users who were successful in quitting, and comparing them to ongoing adult marijuana users, factors that may assist in helping an individual quit \u2014 such as certain motivations for quitting \u2014 may be identified. To study these issues, data was collected from 507 participants from the Pittsburgh Youth Study. It was found that adolescents who used marijuana weekly for at least one year were likely to be ongoing marijuana users in adulthood and that adolescents who had a warm relationship with their primary caretaker were likely to have quit marijuana by adulthood. It was also found that Black participants were more likely to have legal, monetary, and religious reasons for quitting than were White participants. Furthermore, participants who used regularly in adolescence were likely to list legal reasons, as well as a concern that marijuana use was needed to feel normal. Finally, it was found that not a single motivation for quitting marijuana was associated with a shorter period of abstinence. The implications of these findings for motivations to quit marijuana are the focus of the discussion.
ContributorsGomez, Kira Elise (Author) / Pardini, Dustin (Thesis director) / Glenberg, Arthur (Committee member) / Meier, Madeline (Committee member) / Department of Psychology (Contributor) / School of Art (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Estradiol (E2) and Levonorgestrel (Levo) are two hormones commonly used in hormone therapy (HT) to decrease symptoms associated with menopause. Both of these hormones have been shown to have beneficial effects on cognition when given alone in a rodent model of menopause. However, it is unknown whether these hormones, when

Estradiol (E2) and Levonorgestrel (Levo) are two hormones commonly used in hormone therapy (HT) to decrease symptoms associated with menopause. Both of these hormones have been shown to have beneficial effects on cognition when given alone in a rodent model of menopause. However, it is unknown whether these hormones, when taken in combination, are beneficial or harmful to cognition. This is a critically important question given that these hormones are most often given in combination versus separately. This thesis is composed of two studies examining the cognitive effects of E2 and Levo using a rat model of surgical menopause. Study 1 assessed how the dose of E2 treatment in rats impacted cognitive performance, and found that low dose E2 enhanced working memory performance. Next, based on the results from Study 1, Study 2 used low dose E2 in combination with different doses of Levo to examine the cognitive effects of several E2 to Levo ratio combinations. The results from Study 2 demonstrated that the combination of low dose E2 with a high dose of Levo at a 1:2 ratio impaired cognition, and that the ratio currently used in HT, 3:1, may also negatively impact cognition. Indeed, there was a dose response effect indicating that working and reference memory performance was incrementally impaired as Levo dose increased. The findings in this thesis suggest that the E2 plus Levo combination is likely not neutral for cognitive function, and prompts further evaluation in menopausal women, as well as drug discovery research to optimize HT using highly controlled preclinical models.
ContributorsBerns-Leone, Claire Elizabeth (Co-author) / Prakapenka, Alesia (Co-author) / Pena, Veronica (Co-author) / Northup-Smith, Steven (Co-author) / Melikian, Ryan (Co-author) / Ladwig, Ducileia (Co-author) / Patel, Shruti (Co-author) / Croft, Corissa (Co-author) / Bimonte-Nelson, Heather (Thesis director) / Glenberg, Arthur (Committee member) / Conrad, Cheryl (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Variability is inherent in human movement, and poses a challenge to researchers attempting to measure balance. Human movement variability was analyzed using two methods: standard deviation and largest Lyapunov exponent. The experiment was a sit-to-stand task with physical and cognitive perturbations. The physical perturbation consisted of stable and unstable platform

Variability is inherent in human movement, and poses a challenge to researchers attempting to measure balance. Human movement variability was analyzed using two methods: standard deviation and largest Lyapunov exponent. The experiment was a sit-to-stand task with physical and cognitive perturbations. The physical perturbation consisted of stable and unstable platform conditions, while the cognitive perturbation consisted of a counting task. The data were collected from 24 healthy young adults. The purpose of this study was to compare the standard deviation and largest Lyapunov exponent as measures of stability, and to determine the Lyapunov exponent's sensitivity to cognitive perturbation. Evidence suggests that the Lyapunov exponent serves as a more accurate indicator of stability than standard deviation, and that it lacks sensitivity to the counting task.
ContributorsJohnson, Jennifer Jeanne (Author) / Amazeen, Polemnia (Thesis director) / Amazeen, Eric (Committee member) / Stone, Gregory (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12