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Description
The use of saliva sampling as a noninvasive way for drug analysis as well as the monitoring systems within the body has become increasingly important in recent research. Because of the growing interest in saliva, this project proposes a way to analyze sodium ion concentration in a saliva solution based

The use of saliva sampling as a noninvasive way for drug analysis as well as the monitoring systems within the body has become increasingly important in recent research. Because of the growing interest in saliva, this project proposes a way to analyze sodium ion concentration in a saliva solution based on its fluorescence level when in the presence of a sodium indicator dye and recorded with a smartphone camera. The dyed sample was placed in a specially designed housing to exclude all ambient light from the images. A source light of known wavelength was used to excite the fluorescent dye and the smartphone camera images recorded the emission light wavelengths. After analysis of the images using ImageJ, it was possible to create a model to determine the level of fluorescence based on sodium ion concentration. The smartphone camera image model was compared to readings from a standard fluorescence plate recorder to test the accuracy of the model. The study found that the model was accurate within 5 % as compared to the fluorescence plate recorder. Based on the results, it was concluded that the method and resulting model proposed in this study is a valid was to analyze saliva or other solutions for their sodium ion concentration via images recorded by a smartphone camera.
ContributorsSmith, Catherine Julia (Author) / Antonio, Garcia (Thesis director) / Caplan, Michael (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical engineering concepts. The gameplay provides fast paced, exciting, and mildly addicting rooms that the player must battle and survive through,

The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical engineering concepts. The gameplay provides fast paced, exciting, and mildly addicting rooms that the player must battle and survive through, followed by an engineering puzzle that must be solved in order to advance to the next room. The objective of this project was to introduce the core concepts of BME to prospective students, rather than attempt to teach an entire BME curriculum. Based on user testing at various phases in the project, we concluded that the gameplay was engaging enough to keep most users' interest through the educational puzzles, and the potential for expanding this project to reach an even greater audience is vast.
ContributorsNitescu, George (Co-author) / Medawar, Alexandre (Co-author) / Spano, Mark (Thesis director) / LaBelle, Jeffrey (Committee member) / Guiang, Kristoffer (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
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Description
Mountain landscapes reflect competition between tectonic processes acting to build topography and erosive processes acting to wear it down. In temperate mountain landscapes, bedrock rivers are the primary erosional agent, setting both the pace of landscape evolution and form of the surrounding topography. Theory predicts that river steepness is sensitive

Mountain landscapes reflect competition between tectonic processes acting to build topography and erosive processes acting to wear it down. In temperate mountain landscapes, bedrock rivers are the primary erosional agent, setting both the pace of landscape evolution and form of the surrounding topography. Theory predicts that river steepness is sensitive to climatic, tectonic, and lithologic factors, which dictate the rates and mechanics of erosional processes. Thus, encoded into topography is an archive of information about forces driving landscape evolution. Decoding this archive, however, is fraught and climate presents a particularly challenging conundrum: despite decades of research describing theoretically how climate should affect topography, unambiguous natural examples from tectonically active landscapes where variations in climate demonstrably influence topography are elusive. In this dissertation, I first present a theoretical framework describing how the spatially varied nature of orographic rainfall patterns, which are ubiquitous features of mountain climates, complicate expectations about how climate should influence river steepness and erosion. I then apply some of these ideas to the northern-central Andes. By analyzing river profiles spanning more than 1500 km across Peru and Bolivia, I show that the regional orographic rainfall pattern this landscape experiences systematically influences fluvial erosional efficiency and thus topography. I also show how common simplifying assumptions built into conventional topographic analysis techniques may introduce biases that undermine detection of climatic signatures in landscapes where climate, tectonics, and lithology all covary – a common condition in mountain landscapes where these techniques are often used. I continue by coupling this analysis with published erosion rates and a new dataset of 25 cosmogenic 10Be catchment average erosion rates. Once the influence of climate is accounted for, functional relationships emerge among channel steepness, erosion rate, and lithology. I then use these functional relationships to produce a calibrated erosion rate map that spans over 300 km of the southern Peruvian Andes. These results demonstrate that accounting for the effects of climate significantly enhances the ability to decode channel steepness patterns. Along with this comes the potential to better understand rates and patterns of tectonic processes, and identify seismic hazards associated with tectonic activity using topography.
ContributorsLeonard, Joel Scott (Author) / Whipple, Kelin (Thesis advisor) / Arrowsmith, Ramon (Committee member) / Christensen, Philip (Committee member) / Forte, Adam (Committee member) / Heimsath, Arjun (Committee member) / Hodges, Kip (Committee member) / Arizona State University (Publisher)
Created2022
Description
The mountains of western North America are spectacular and diverse, from sheer walls of crumbling black limestone in the Canadian Rockies, to smooth glacially polished granite in the Wind River Range, to gargantuan ice-clad volcanoes in the Cascades. These great bastions of rock, snow, and ice, still very much wild

The mountains of western North America are spectacular and diverse, from sheer walls of crumbling black limestone in the Canadian Rockies, to smooth glacially polished granite in the Wind River Range, to gargantuan ice-clad volcanoes in the Cascades. These great bastions of rock, snow, and ice, still very much wild and untamed, provide an incredible arena for adventure, exploration, and challenge. Over the past three years, I have devoted thousands of hours to exploring these vast wild places, climbing high peaks, steep cliffs, and frozen waterfalls. In doing so, I studied the rich geologic history of the mountains. This thesis project is a compilation of stories and images from those adventures, along with the stories of the mountains themselves: how the rocks were formed, thrust skyward, and sculpted over the ages into their present, glorious form. The photographic and detailed narrative of the geology and adventures is on a new website called Cloud Piercers, which currently features three geologically diverse mountain massifs: (1) Mount Rainier, an active volcano in the Cascade Range of Washington; (2) Mount Robson, the highest peak in the Canadian Rockies, within a terrain of folded Paleozoic sedimentary rocks; and (3) the Wind River Range of Wyoming, composed mostly of Archean metamorphic and granitic rocks. This website will be expanded in the future as the geologic studies and adventures continue.
ContributorsSteadman, Dane Kyle (Author) / Reynolds, Stephen (Thesis director) / Johnson, Julia (Committee member) / Heimsath, Arjun (Committee member) / School of Earth and Space Exploration (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Faults found in the arid to semi-arid Basin and Range Physiographic province of the southwestern US are given broad age definitions in terms of which features appear to be the oldest. Particularly in the northwestern corner of Arizona, detailed geomorphic studies on the tectonic history and timing of faulting are

Faults found in the arid to semi-arid Basin and Range Physiographic province of the southwestern US are given broad age definitions in terms of which features appear to be the oldest. Particularly in the northwestern corner of Arizona, detailed geomorphic studies on the tectonic history and timing of faulting are not widespread. At the base of the Virgin Mountains in northwestern Arizona is a fault scarp along the Piedmont Fault line. This normal fault crosses a series of alluvial fans that are filled with sediments of ambiguous ages. Previous studies that were done in this region find a broad, Miocene age for the exhumation and uplift of these surfaces, with some indications of Laramide faulting history. However, specific fault characteristics and a time constraint of the tectonic history of the Piedmont Fault scarp has yet to be established. Here, we aim to determine the age, fault-slip rate, seismic history, and potential hazard of the fault scarp near Scenic and Littlefield, Arizona through structure from motion (SfM) modeling, which is a form of photogrammetry using a drone. In addition, we distinguish the climatic and tectonic influences on the geomorphology observed along the scarp through analysis along the fault line. With data collected from a ~500 m section of the fault, we present results from a digital elevation model (DEM) and orthophotos derived through the SfM modelling. Based on field observations and morphologic dating, we determine that the Piedmont Fault experiences an approximately continuous fault-slip and an earthquake recurrence interval in the range of 7,000 years. The approximate age of the scarp is 16.0 ka ± 5 kyr. Therefore, we conclude that the earthquake hazard posed to nearby cities is minimal but not nonexistent. Future work includes further analysis of fault profiles due to uncertainty in the present one and Terrestrial Cosmogenic Nuclide (TCN) dating of samples taken from the tops of boulders in a residual debris flow sitting on faulted and unfaulted alluvia. Determining the ages for these boulder surfaces can hopefully further inform our knowledge of the tectonic activity present in the North Virgin Mountains.
ContributorsApel, Emily Virginia (Author) / Heimsath, Arjun (Thesis director) / Arrowsmith, Ramon (Committee member) / Whipple, Kelin (Committee member) / School of Molecular Sciences (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12