Search Content

Heron Lodge

Description

Heron Lodge is the hybrid product of sciences, (pre) medicine, and the humanities throughout four years of an undergraduate degree in Medical Studies.

ContributorsLu, Emilie Joy (Author) / Dombrowski, Rosemarie (Thesis director) / Viren, Sarah (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)

Created2021-05

Reading and Writing Military Science Fiction

DescriptionDiscusses the reading experience and writing strategies in relation to four prominent novels from the genre

ContributorsO'Malley, Erik Andrew (Author) / Cook, Paul (Thesis director) / Mallot, Edward (Committee member) / Broglio, Ronald (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Department of English (Contributor)

Created2013-05

You Gotta Eat the Lettuce: An Examination of the Effects of Lutein and Zeaxanthin on Contrast Sensitivity

Description

Lutein and zeaxanthin are two important carotenoid vitamins related to ocular health and human visual processing. These vitamins can be ingested through supplementation and in regular diet. They concentrate in the central retina where they form a filter of macular pigment and protect the eye from high energy blue and…

Lutein and zeaxanthin are two important carotenoid vitamins related to ocular health and human visual processing. These vitamins can be ingested through supplementation and in regular diet. They concentrate in the central retina where they form a filter of macular pigment and protect the eye from high energy blue and yellow light. We examined participants who had a natural diet of high vs low lutein and zeaxanthin intake on tests of contrast sensitivity and glare disability. We also examined participant performance while wearing blue light blocking glasses in order to determine whether these glasses serve a similar protective function as macular pigment in benefiting participants on contrast sensitivity and glare disability tasks. Most of our data did not show statistically significant differences between the high and low lutein and zeaxanthin groups. An unexpected result that the blue blocker glasses hindered the ability of low lutein participants on their glare disability test was observed. We hypothesize that this is due to light scatter produced by the by glasses resulting in an impoverish retinal image reaching the primary visual cortex. Further research is required to examine this new finding.

ContributorsHormann, Breanna Susanne (Author) / Holloway, Steven (Thesis director) / Náñez Sr., José E (Committee member) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)

Created2019-05

COMBATING CANCER AND ALZHEIMER'S DISEASE: SYNTHESIS OF NOVEL, CHEMOTHERAPEUTIC REXINOIDS

Description

The FDA-approved drug bexarotene has been predominantly utilized for the treatment of cutaneous T-cell lymphoma (CTLC), but has shown promise as an off label treatment for various other cancers as well as Alzheimer's disease (AD). However, harmful side effects such as hypothyroidism have catalyzed a search for alternative rexinoids which…

The FDA-approved drug bexarotene has been predominantly utilized for the treatment of cutaneous T-cell lymphoma (CTLC), but has shown promise as an off label treatment for various other cancers as well as Alzheimer's disease (AD). However, harmful side effects such as hypothyroidism have catalyzed a search for alternative rexinoids which retain similar levels of RXR agonism while reducing the undesirable effects incurred by bexarotene. This honors thesis outlines the steps taken to design and synthesize novel analogues of the selective retinoid-X-receptor (RXR) agonist 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). Corresponding NMR spectra indicates the successful construction of four novel compounds which are structurally similar to known, biologically-evaluated rexinoids that have induced fewer side effects while stimulating greater levels of RXR selectivity as compared to bexarotene. Future In vitro analyses of these four analogues coupled with the recognized efficacy of their parent compounds demonstrate the chemotherapeutic potential of structurally modified bexarotene analogues

ContributorsDavidson, Jesse Raymond (Author) / Wagner, Carl (Thesis director) / Ball, Rebecca (Committee member) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)

Created2016-05

Quantum Physics and the Double-Slit Experiment

Description

Our work explores a fascinating experiment in physics and science, the Double-Slit Experiment. We cover the mystery of this experiment, representing the wave and particle nature of photons, electrons, and quantum elements. We recount the history of quantum physics, an unknown field for most people due to its detachment from…

Our work explores a fascinating experiment in physics and science, the Double-Slit Experiment. We cover the mystery of this experiment, representing the wave and particle nature of photons, electrons, and quantum elements. We recount the history of quantum physics, an unknown field for most people due to its detachment from the world we see. Finally, we explore the capability of the human eye to detect light in its quantum state, closing the gap between us and quantum physics.

ContributorsAndersen, Liam (Author) / Bujan, Reynaldo R. (Co-author) / Foy, Joseph (Thesis director) / Martin, Thomas (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)

Created2022-05

Quantum Physics and the Double-Slit Experiment

Description

Our work explores a fascinating experiment in physics and science, the Double-Slit Experiment. We cover the mystery of this experiment, representing the wave and particle nature of photons, electrons, and quantum elements. We recount the history of quantum physics, an unknown field for most people due to its detachment from…

Our work explores a fascinating experiment in physics and science, the Double-Slit Experiment. We cover the mystery of this experiment, representing the wave and particle nature of photons, electrons, and quantum elements. We recount the history of quantum physics, an unknown field for most people due to its detachment from the world we see. Finally, we explore the capability of the human eye to detect light in its quantum state, closing the gap between us and quantum physics.

ContributorsBujan, Reynaldo R. (Author) / Andersen, Liam (Co-author) / Foy, Joseph (Thesis director) / Martin, Thomas (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)

Created2022-05

The Instability of Life: Growing as a Philosopher, Scientist, and Woman

Description

Throughout the year I had the opportunity to work on a business venture that utilized dendrites as a unique identifier. Dendrites themselves are completely unique, random, branching structures that occur everywhere in nature. This creative project was inspired by the shape of the dendrite and I created a series of…

Throughout the year I had the opportunity to work on a business venture that utilized dendrites as a unique identifier. Dendrites themselves are completely unique, random, branching structures that occur everywhere in nature. This creative project was inspired by the shape of the dendrite and I created a series of 12 paintings reflecting on my own unique college journey.

ContributorsMann, Abigail (Author) / Trujillo, Rhett (Thesis director) / Reeves, James (Committee member) / Barrett, The Honors College (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Mathematical and Natural Sciences (Contributor)

Created2022-05

Using an Active Case Based Learning Model to Increase Scientific Interest, Understanding of and Confidence in the Process of Science in Secondary Education

Description

Many high school students demonstrate an overall lack of interest in science. Traditional teaching methodologies seem to be unsuccessful at engaging students \u2014 one explanation is that students often interpret what they learn in school as irrelevant to their personal lives. Active learning and case based learning methodologies seem to…

Many high school students demonstrate an overall lack of interest in science. Traditional teaching methodologies seem to be unsuccessful at engaging students \u2014 one explanation is that students often interpret what they learn in school as irrelevant to their personal lives. Active learning and case based learning methodologies seem to be more effective at promoting interest and understanding of scientific principles. The purpose of our research was to implement a lab with updated teaching methodologies that included an active learning and case based curriculum. The lab was implemented in two high school honors biology classes with the specific goals of: significantly increasing students' interest in science and its related fields; increasing students' self-efficacy in their ability to understand and interpret the traditional process of the scientific method; and increasing this traditional process of objectively understanding the scientific method. Our results indicated that interest in science and its related fields (p = .011), students' self-efficacy in understanding the scientific method (p = .000), and students' objective understanding of the scientific method (p = .000) statistically significantly increased after the lab was administered; however, our results may not be as meaningful as the p-values imply due to the scale of our assessment.

ContributorsCotten, Kathryn (Author) / Hoffner, Kristin (Thesis director) / Stout, Valerie (Committee member) / Lynskey, Jim (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)

Created2012-12

Filtering by