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The purpose of this longitudinal study was to predict /r/ acquisition using acoustic signal processing. 19 children, aged 5-7 with inaccurate /r/, were followed until they turned 8 or acquired /r/, whichever came first. Acoustic and descriptive data from 14 participants were analyzed. The remaining 5 children continued to be

The purpose of this longitudinal study was to predict /r/ acquisition using acoustic signal processing. 19 children, aged 5-7 with inaccurate /r/, were followed until they turned 8 or acquired /r/, whichever came first. Acoustic and descriptive data from 14 participants were analyzed. The remaining 5 children continued to be followed. The study analyzed differences in spectral energy at the baseline acoustic signals of participants who eventually acquired /r/ compared to that of those who did not acquire /r/. Results indicated significant differences between groups in the baseline signals for vocalic and postvocalic /r/, suggesting that the acquisition of certain allophones may be predictable. Participants’ articulatory changes made during the progression of acquisition were also analyzed spectrally. A retrospective analysis described the pattern in which /r/ allophones were acquired, proposing that vocalic /r/ and the postvocalic variant of consonantal /r/ may be acquired prior to prevocalic /r/, and /r/ followed by low vowels may be acquired before /r/ followed by high vowels, although individual variations exist.

ContributorsConger, Sarah Grace (Author) / Weinhold, Juliet (Thesis director) / Daliri, Ayoub (Committee member) / Bruce, Laurel (Committee member) / College of Health Solutions (Contributor, Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The distinctions between the neural resources supporting speech and music comprehension have long been studied using contexts like aphasia and amusia, and neuroimaging in control subjects. While many models have emerged to describe the different networks uniquely recruited in response to speech and music stimuli, there are still many questions,

The distinctions between the neural resources supporting speech and music comprehension have long been studied using contexts like aphasia and amusia, and neuroimaging in control subjects. While many models have emerged to describe the different networks uniquely recruited in response to speech and music stimuli, there are still many questions, especially regarding left-hemispheric strokes that disrupt typical speech-processing brain networks, and how musical training might affect the brain networks recruited for speech after a stroke. Thus, our study aims to explore some questions related to the above topics. We collected task-based functional MRI data from 12 subjects who previously experienced a left-hemispheric stroke. Subjects listened to blocks of spoken sentences and novel piano melodies during scanning to examine the differences in brain activations in response to speech and music. We hypothesized that speech stimuli would activate right frontal regions, and music stimuli would activate the right superior temporal regions more than speech (both findings not seen in previous studies of control subjects), as a result of functional changes in the brain, following the left-hemispheric stroke and particularly the loss of functionality in the left temporal lobe. We also hypothesized that the music stimuli would cause a stronger activation in right temporal cortex for participants who have had musical training than those who have not. Our results indicate that speech stimuli compared to rest activated the anterior superior temporal gyrus bilaterally and activated the right inferior frontal lobe. Music stimuli compared to rest did not activate the brain bilaterally, but rather only activated the right middle temporal gyrus. When the group analysis was performed with music experience as a covariate, we found that musical training did not affect activations to music stimuli specifically, but there was greater right hemisphere activation in several regions in response to speech stimuli as a function of more years of musical training. The results of the study agree with our hypotheses regarding the functional changes in the brain, but they conflict with our hypothesis about musical expertise. Overall, the study has generated interesting starting points for further explorations of how musical neural resources may be recruited for speech processing after damage to typical language networks.

ContributorsKarthigeyan, Vishnu R (Author) / Rogalsky, Corianne (Thesis director) / Daliri, Ayoub (Committee member) / Harrington Bioengineering Program (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The phenomenon known as startReact is the fast, involuntary execution of a planned movement triggered by a startling acoustic stimulus. StartReact has previously been analyzed in simple motor movements such as finger abduction tasks, hand grasp tasks, and elbow extension tasks. More complex movements have also been analyzed, but there

The phenomenon known as startReact is the fast, involuntary execution of a planned movement triggered by a startling acoustic stimulus. StartReact has previously been analyzed in simple motor movements such as finger abduction tasks, hand grasp tasks, and elbow extension tasks. More complex movements have also been analyzed, but there have been limited studies that look into functional complex tasks that require end-point accuracy. The objective of this project was to assess the ability to elicit startReact in tasks that simulate activities of daily living like feeding or picking up a glass of water. We hypothesized that a startReact response would be present in complex functional tasks, but the response would not be as accurate due to the increase in speed. Five subjects performed a simulated feeding task by moving kidney beans from one target to another where the end target changed in diameter as well as, a simulated drinking task where the subject moved a cup full of beads from one target to another. The hypothesis was supported due to a significant difference between no stimulus and stimulus trials for tricep muscle onset time, duration time, and the accuracy parameters of amount of beans dropped and weight in beads dropped. The results coincided with previous studies where subjects compensated for the change in diameter by increasing reaction time as the target diameter size decreased. The data obtained contradicted a previous study in relation to the duration time between the tasks due to our smallest diameter size having a faster duration time in comparison to the other diameter sizes. This study provides preliminary data that could assist researchers and clinicians in improving physical therapy methods for patients with impaired upper extremity motor movements.
ContributorsRiggs, Cassie Rebekah (Author) / Honeycutt, Claire (Thesis director) / Schaefer, Sydney (Committee member) / Harrington Bioengineering Program (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Stroke is the fifth most common cause of death in America and a leading cause of long-term adult disability, affecting more than 795,000 people a year ("American Stroke Association: A Division of the American Heart Association"). Many of these individuals experience persistent difficulty with the execution of daily tasks as

Stroke is the fifth most common cause of death in America and a leading cause of long-term adult disability, affecting more than 795,000 people a year ("American Stroke Association: A Division of the American Heart Association"). Many of these individuals experience persistent difficulty with the execution of daily tasks as a direct consequence of a stroke. A key factor in the successful recovery of a stroke survivor is rehabilitation. Rehabilitation sessions can start within two days of the stroke if the patient is in stable condition, and often continues long after their release from the hospital ("American Stroke Association: A Division of the American Heart Association"). The rehabilitation sessions are driven by a team of rehabilitation care professionals which includes, but is not limited to a physical therapist, occupational therapist, and speech-language pathologist. These professionals are available to the stroke survivor as resources to assist in developing and organizing ways to achieve independence as opposed to dependence. Ultimately, a stroke survivor’s family typically provides the most important long-term support during recovery and rehabilitation ("American Stroke Association: A Division of the American Heart Association"). However, there is very little research that focuses on the impact that local family can have on the stroke survivor’s establishment and achievement of goals throughout their recovery and rehabilitation. This study examines this gap in knowledge.
ContributorsGraves, Migail (Author) / Rogalsky, Corianne (Thesis director) / Schaefer, Sydney (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
Previous research has showed that auditory modulation may be affected by pure tone
stimuli played prior to the onset of speech production. In this experiment, we are examining the
specificity of the auditory stimulus by implementing congruent and incongruent speech sounds in
addition to non-speech sound. Electroencephalography (EEG) data was recorded for eleven

Previous research has showed that auditory modulation may be affected by pure tone
stimuli played prior to the onset of speech production. In this experiment, we are examining the
specificity of the auditory stimulus by implementing congruent and incongruent speech sounds in
addition to non-speech sound. Electroencephalography (EEG) data was recorded for eleven adult
subjects in both speaking (speech planning) and silent reading (no speech planning) conditions.
Data analysis was accomplished manually as well as via generation of a MATLAB code to
combine data sets and calculate auditory modulation (suppression). Results of the P200
modulation showed that modulation was larger for incongruent stimuli than congruent stimuli.
However, this was not the case for the N100 modulation. The data for pure tone could not be
analyzed because the intensity of this stimulus was substantially lower than that of the speech
stimuli. Overall, the results indicated that the P200 component plays a significant role in
processing stimuli and determining the relevance of stimuli; this result is consistent with role of
P200 component in high-level analysis of speech and perceptual processing. This experiment is
ongoing, and we hope to obtain data from more subjects to support the current findings.
ContributorsTaylor, Megan Kathleen (Author) / Daliri, Ayoub (Thesis director) / Liss, Julie (Committee member) / School of Life Sciences (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
Previous studies have found that the detection of near-threshold stimuli is decreased immediately before movement and throughout movement production. This has been suggested to occur through the use of the internal forward model processing an efferent copy of the motor command and creating a prediction that is used to cancel

Previous studies have found that the detection of near-threshold stimuli is decreased immediately before movement and throughout movement production. This has been suggested to occur through the use of the internal forward model processing an efferent copy of the motor command and creating a prediction that is used to cancel out the resulting sensory feedback. Currently, there are no published accounts of the perception of tactile signals for motor tasks and contexts related to the lips during both speech planning and production. In this study, we measured the responsiveness of the somatosensory system during speech planning using light electrical stimulation below the lower lip by comparing perception during mixed speaking and silent reading conditions. Participants were asked to judge whether a constant near-threshold electrical stimulation (subject-specific intensity, 85% detected at rest) was present during different time points relative to an initial visual cue. In the speaking condition, participants overtly produced target words shown on a computer monitor. In the reading condition, participants read the same target words silently to themselves without any movement or sound. We found that detection of the stimulus was attenuated during speaking conditions while remaining at a constant level close to the perceptual threshold throughout the silent reading condition. Perceptual modulation was most intense during speech production and showed some attenuation just prior to speech production during the planning period of speech. This demonstrates that there is a significant decrease in the responsiveness of the somatosensory system during speech production as well as milliseconds before speech is even produced which has implications for speech disorders such as stuttering and schizophrenia with pronounced deficits in the somatosensory system.
ContributorsMcguffin, Brianna Jean (Author) / Daliri, Ayoub (Thesis director) / Liss, Julie (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
During speech, the brain is constantly processing and monitoring speech output through the auditory feedback loop to ensure correct and accurate speech. If the speech signal is experimentally altered/perturbed while speaking, the brain compensates for the perturbations by changing speech output in the opposite direction of the perturbations. In this

During speech, the brain is constantly processing and monitoring speech output through the auditory feedback loop to ensure correct and accurate speech. If the speech signal is experimentally altered/perturbed while speaking, the brain compensates for the perturbations by changing speech output in the opposite direction of the perturbations. In this study, we designed an experiment that examined the compensatory responses in response to unexpected vowel perturbations during speech. We applied two types of perturbations. In one condition, the vowel /ɛ/ was perturbed toward the vowel /æ/ by simultaneously shifting both the first formant (F1) and the second formant (F2) at 3 different levels (.5=small, 1=medium, and 1.5=large shifts). In another condition, the vowel /ɛ/ was perturbed by shifting F1 at 3 different levels (small, medium, and large shifts). Our results showed that there was a significant perturbation-type effect, with participants compensating more in response to perturbation that shifted /ɛ/ toward /æ/. In addition, we found that there was a significant level effect, with the compensatory responses to level .5 being significantly smaller than the compensatory responses to levels 1 and 1.5, regardless of the perturbation pathway. We also found that responses to shift level 1 and shift level 1.5 did not differ. Overall, our results highlighted the importance of the auditory feedback loop during speech production and how the brain is more sensitive to auditory errors that change a vowel category (e.g., /ɛ/ to /æ/).
ContributorsFitzgerald, Lacee (Author) / Daliri, Ayoub (Thesis director) / Corianne, Rogalsky (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
The objective of this study was to analyze the auditory feedback system and the pitch-shift reflex in relation to vibrato. 11 subjects (female n = 8, male n = 3) without speech, hearing, or neurological disorders were used. Compensation magnitude, adaptation magnitude, relative response phase, and passive and active perception

The objective of this study was to analyze the auditory feedback system and the pitch-shift reflex in relation to vibrato. 11 subjects (female n = 8, male n = 3) without speech, hearing, or neurological disorders were used. Compensation magnitude, adaptation magnitude, relative response phase, and passive and active perception were recorded when the subjects were subjected to auditory feedback perturbed by phasic amplitude and F0 modulation, or “vibrato”. “Tremolo,” or phasic amplitude modulation, was used as a control. Significant correlation was found between the ability to perceive vibrato and tremolo in active trials and the ability to perceive in passive trials (p=0.01). Passive perceptions were lower (more sensitive) than active perceptions (p< 0.01). Adaptation vibrato trials showed significant modulation magnitude (p=0.031), while tremolo did not. The two conditions were significantly different (p<0.01). There was significant phase change for both tremolo and vibrato, but vibrato phase change was greater, nearly 180° (p<0.01). In the compensation trials, the modulation change from control to vibrato trials was significantly greater than the change from control to tremolo (p=0.01). Vibrato and tremolo also had significantly different average phase change (p<0.01). It can be concluded that the auditory feedback system tries to cancel out dynamic pitch perturbations by cancelling them out out-of-phase. Similar systems must be used to adapt and to compensate to vibrato. Despite the auditory feedback system’s online monitoring, the passive perception was still better than active perception, possibly because it required only one task (perceiving) rather than two (perceiving and producing). The pitch-shift reflex compensates to the sensitivity of the auditory feedback system, as shown by the increased perception of vibrato over tremolo.
ContributorsHiggins, Alexis Brittany (Author) / Daliri, Ayoub (Thesis director) / Liss, Julie (Committee member) / Luo, Xin (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Previous research has shown that a loud acoustic stimulus can trigger an individual's prepared movement plan. This movement response is referred to as a startle-evoked movement (SEM). SEM has been observed in the stroke survivor population where results have shown that SEM enhances single joint movements that are usually performed

Previous research has shown that a loud acoustic stimulus can trigger an individual's prepared movement plan. This movement response is referred to as a startle-evoked movement (SEM). SEM has been observed in the stroke survivor population where results have shown that SEM enhances single joint movements that are usually performed with difficulty. While the presence of SEM in the stroke survivor population advances scientific understanding of movement capabilities following a stroke, published studies using the SEM phenomenon only examined one joint. The ability of SEM to generate multi-jointed movements is understudied and consequently limits SEM as a potential therapy tool. In order to apply SEM as a therapy tool however, the biomechanics of the arm in multi-jointed movement planning and execution must be better understood. Thus, the objective of our study was to evaluate if SEM could elicit multi-joint reaching movements that were accurate in an unrestrained, two-dimensional workspace. Data was collected from ten subjects with no previous neck, arm, or brain injury. Each subject performed a reaching task to five Targets that were equally spaced in a semi-circle to create a two-dimensional workspace. The subject reached to each Target following a sequence of two non-startling acoustic stimuli cues: "Get Ready" and "Go". A loud acoustic stimuli was randomly substituted for the "Go" cue. We hypothesized that SEM is accessible and accurate for unrestricted multi-jointed reaching tasks in a functional workspace and is therefore independent of movement direction. Our results found that SEM is possible in all five Target directions. The probability of evoking SEM and the movement kinematics (i.e. total movement time, linear deviation, average velocity) to each Target are not statistically different. Thus, we conclude that SEM is possible in a functional workspace and is not dependent on where arm stability is maximized. Moreover, coordinated preparation and storage of a multi-jointed movement is indeed possible.
ContributorsOssanna, Meilin Ryan (Author) / Honeycutt, Claire (Thesis director) / Schaefer, Sydney (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
Stroke is the leading cause of long-term disability in the U.S., with up to 60% of strokescausing speech loss. Individuals with severe stroke, who require the most frequent, intense speech therapy, often cannot adhere to treatments due to high cost and low success rates. Therefore, the ability to make functionally

Stroke is the leading cause of long-term disability in the U.S., with up to 60% of strokescausing speech loss. Individuals with severe stroke, who require the most frequent, intense speech therapy, often cannot adhere to treatments due to high cost and low success rates. Therefore, the ability to make functionally significant changes in individuals with severe post- stroke aphasia remains a key challenge for the rehabilitation community. This dissertation aimed to evaluate the efficacy of Startle Adjuvant Rehabilitation Therapy (START), a tele-enabled, low- cost treatment, to improve quality of life and speech in individuals with severe-to-moderate stroke. START is the exposure to startling acoustic stimuli during practice of motor tasks in individuals with stroke. START increases the speed and intensity of practice in severely impaired post-stroke reaching, with START eliciting muscle activity 2-3 times higher than maximum voluntary contraction. Voluntary reaching distance, onset, and final accuracy increased after a session of START, suggesting a rehabilitative effect. However, START has not been evaluated during impaired speech. The objective of this study is to determine if impaired speech can be elicited by startling acoustic stimuli, and if three days of START training can enhance clinical measures of moderate to severe post-stroke aphasia and apraxia of speech. This dissertation evaluates START in 42 individuals with post-stroke speech impairment via telehealth in a Phase 0 clinical trial. Results suggest that impaired speech can be elicited by startling acoustic stimuli and that START benefits individuals with severe-to-moderate post-stroke impairments in both linguistic and motor speech domains. This fills an important gap in aphasia care, as many speech therapies remain ineffective and financially inaccessible for patients with severe deficits. START is effective, remotely delivered, and may likely serve as an affordable adjuvant to traditional therapy for those that have poor access to quality care.
ContributorsSwann, Zoe Elisabeth (Author) / Honeycutt, Claire F (Thesis advisor) / Daliri, Ayoub (Committee member) / Rogalsky, Corianne (Committee member) / Liss, Julie (Committee member) / Schaefer, Sydney (Committee member) / Arizona State University (Publisher)
Created2022