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To examine the effect of an 8-week cycling intervention on short term and working memory in adolescents with Down syndrome (DS), participants were divided into Assisted Cycling Therapy (ACT), Voluntary Cycling (VC), or No Cycling (NC) groups. Forward and backward digit span assessments were administered prior to and after the

To examine the effect of an 8-week cycling intervention on short term and working memory in adolescents with Down syndrome (DS), participants were divided into Assisted Cycling Therapy (ACT), Voluntary Cycling (VC), or No Cycling (NC) groups. Forward and backward digit span assessments were administered prior to and after the intervention to evaluate short term and working memory respectively. 8 weeks of exercise via ACT showed a trend toward conventional levels of significance in the number of levels completed in the backward direction.
ContributorsSandoval-Menendez, Amber Melanie (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Blais, Chris (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
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The purpose of this study, originally, was to contribute to the completion of a meta-analysis conducted by Mara Wierstra from the University of Virginia. Wierstra had requested individual participant data from two separate studies conducted in our lab: "Acute bouts of assisted cycling improves cognitive and upper extremity movement functions

The purpose of this study, originally, was to contribute to the completion of a meta-analysis conducted by Mara Wierstra from the University of Virginia. Wierstra had requested individual participant data from two separate studies conducted in our lab: "Acute bouts of assisted cycling improves cognitive and upper extremity movement functions in adolescents with Down syndrome" and "Assisted Cycling Therapy (ACT) improves inhibition in adolescents with autism spectrum disorder." From the data requested, the participants were required to complete three separate tests (i.e., Tower of London, Trail Making Task and the Stroop Test). After compiling the data and sending it to her, we decided to conduct a small meta-analysis of our own, drawing connecting conclusions from the data from the two studies. We concluded that observationally our data suggest an advantage for ACT over voluntary cycling and no cycling across two separate populations (i.e., Autism Spectrum Disorder and Down syndrome), and across different measures of executive function (i.e., Stroop Test, Trail Making Test, and Tower of London). The data suggest that the ACT interventions may promote the upregulation of neurotropic factors leading to neurogenesis in the prefrontal cortex of the brain.
ContributorsParker, Cade Joseph (Author) / Ringenbach, Shannon (Thesis director) / Holzapfel, Simon (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description

Down syndrome (DS) is caused by either an extra copy of chromosome 21 or by extra material on chromosome 21. This causes various levels of intellectual disability and issues with gross motor skill development which can prevent these individuals from participating in activities of daily living (ADL) such as getting

Down syndrome (DS) is caused by either an extra copy of chromosome 21 or by extra material on chromosome 21. This causes various levels of intellectual disability and issues with gross motor skill development which can prevent these individuals from participating in activities of daily living (ADL) such as getting dressed, self-care, or grocery shopping. People with DS have a decreased ability to balance, an abnormal and slower gait pattern, difficulty adapting to new environments, and a lack of improvement in these areas with growth and development when compared to their neurotypical peers. The objective of this study was to determine the immediate effects of resistance training (RT) and assisted cycle therapy (ACT) on adults with DS’s balance ability and gait speed. Each participant completed one session of RT, ACT (stationary cycling with the assistance of a motor to maintain a cadence of at least 35% greater than their voluntary cycling speed), and no training in a randomly selected order. Balance and gait speed were measured by a Clinical Test of Sensory Interaction on Balance (CTSIB) (i.e., eyes open firm surface, eyes closed firm surface, eyes open foam surface, eyes closed foam surface) on a Balance Tracking System Board (Btracks board) and by a Timed Up and Go (TUG) test. A total of ten participants’ data was used for analysis. The measures of total path length (cm), anterior-posterior (AP) excursion, and medial-lateral (ML) excursion were used to analyze the CTSIB. The average time was used to analyze the TUG test. The results showed that the eyes closed foam surface balance task was the most challenging balance task for every participant in every intervention. Furthermore, the most improvement was evident in the eyes closed foam surface balance task from pre to post intervention in all of the interventions. Post hoc tests also indicated statistically significant improvements of path length from pre to post in the RT intervention with the eyes closed foam surface balance task as well as with AP excursion in the ACT intervention with the eyes closed foam surface balance task. Possible explanations for improvements from pre to post in the eyes closed foam balance task across all interventions will be discussed with respect to the length of the intervention, and the effect of strength, social and learned factors on balance in adults with DS.

ContributorsKeim, Jeannette Danielle (Author) / Ringenbach, Shannon (Thesis director) / Peterson, Daniel (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
The genetic disorder Down syndrome (DS), clinically known as Trisomy 21, is characterized by the presence of either a part or full extra copy of chromosome 21. When compared with children of typical development, children with DS consistently score lower on gross motor skill tasks. Balance specifically is one of

The genetic disorder Down syndrome (DS), clinically known as Trisomy 21, is characterized by the presence of either a part or full extra copy of chromosome 21. When compared with children of typical development, children with DS consistently score lower on gross motor skill tasks. Balance specifically is one of the hardest skills for individuals with DS (especially children) to acquire, and neglecting to train balance early on can predispose individuals with DS to further movement instabilities, injuries, social struggles from activity limitations, and an overall lack of independence. One of the more unique forms of physical activity that requires a large amount of both static and dynamic balance is ballet. Dance-specific therapy has been shown to improve gross motor control functioning and specifically balance in a variety of populations with neuromuscular condions, but the research around ballet-specific therapy for those with DS is lacking. The purpose of this pilot study was to further investigate the effects of ballet-specific training on balance ability and general motor functioning in young students with DS as measured by the Four Square Step Test (FSST), Pediatric Balance Scale (PBS), and the gross and fine motor domains of the Vineland Adaptive Behavior Scale lll (VABS lll). It was hypothesized that participation in the 6-week summer cohort of Ballet Arizona’s Adaptive Dance Program would lead to improved scores on the PBS and VABS lll and decreased test times in the FSST. Improvements were observed for all measures for both participants (sample size n=2), except for P1's FSST, which increased in post-testing by 2.25s. Due to the study design, no conclusive statements can be made about whether the ballet program was responsible for the improvements observed in post-testing. More rigorous research with larger sample sizes (>30) is warranted to more fully understand the impact of an adapted ballet program on the balance ability of young individuals with DS. However, the program is still recommended for young individuals with DS because of the benefits it provides outside of motor skill development.
ContributorsMitrovic, Jelena (Author) / Peterson, Daniel (Thesis director) / Holzapfel, Simon (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-12
Description
Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for

Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for the high termination rates. In an attempt to understand the reasons behind the high termination rates the following question must be addressed: “What information is available to pregnant women that may influence their decision to terminate or not terminate fetuses with Trisomy 21?” In order to answer this question I completed a comprehensive literature review of the information available to pregnant women in the United States after they find out there fetus has Trisomy 21. The results showed that many sources publish information that is straightforward, factual, and attempts to make sure that pregnant women are fully informed on the reality of life with a child with Down syndrome. However, there are also many sources that publish information that is biased and attempts to influence a woman’s decision of whether to keep or abort her fetus with Trisomy 21. The results from this study suggest that the message conveyed from a given article relies heavily on who is doing the writing, the type of article it is, and were it is published. This provides women with a confusing array of different ideas, as opposed to offering them objective facts and consistent information. When a pregnant woman is told that her fetus is positive for the Trisomy 21 disorder and will be born with Down syndrome, it can be a very scary and emotional time. Women in this situation deserve easy access the correct information in order to help them make an informed decision based on their own choice and not the opinion of someone else.
ContributorsFitzgerald, Grace (Author) / Maienschein, Jane (Thesis director) / Ziganshina, Dina (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Molecular Sciences (Contributor)
Created2022-05
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Description

Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for

Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for the high termination rates. In an attempt to understand the reasons behind the high termination rates the following question must be addressed: “What information is available to pregnant women that may influence their decision to terminate or not terminate fetuses with Trisomy 21?” In order to answer this question I completed a comprehensive literature review of the information available to pregnant women in the United States after they find out there fetus has Trisomy 21. The results showed that many sources publish information that is straightforward, factual, and attempts to make sure that pregnant women are fully informed on the reality of life with a child with Down syndrome. However, there are also many sources that publish information that is biased and attempts to influence a woman’s decision of whether to keep or abort her fetus with Trisomy 21. The results from this study suggest that the message conveyed from a given article relies heavily on who is doing the writing, the type of article it is, and were it is published. This provides women with a confusing array of different ideas, as opposed to offering them objective facts and consistent information. When a pregnant woman is told that her fetus is positive for the Trisomy 21 disorder and will be born with Down syndrome, it can be a very scary and emotional time. Women in this situation deserve easy access the correct information in order to help them make an informed decision based on their own choice and not the opinion of someone else.

ContributorsFitzgerald, Grace (Author) / Maienschein, Jane (Thesis director) / Ziganshina, Dina (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2022-05
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Description

Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for

Statistics show that the termination rates for fetuses with Down syndrome are substantially higher compared to the general population. Perhaps pregnant women are led to believe that this is the best option for them. The information that leads them to this conclusion could be one of the leading factors for the high termination rates. In an attempt to understand the reasons behind the high termination rates the following question must be addressed: “What information is available to pregnant women that may influence their decision to terminate or not terminate fetuses with Trisomy 21?” In order to answer this question I completed a comprehensive literature review of the information available to pregnant women in the United States after they find out there fetus has Trisomy 21. The results showed that many sources publish information that is straightforward, factual, and attempts to make sure that pregnant women are fully informed on the reality of life with a child with Down syndrome. However, there are also many sources that publish information that is biased and attempts to influence a woman’s decision of whether to keep or abort her fetus with Trisomy 21. The results from this study suggest that the message conveyed from a given article relies heavily on who is doing the writing, the type of article it is, and were it is published. This provides women with a confusing array of different ideas, as opposed to offering them objective facts and consistent information. When a pregnant woman is told that her fetus is positive for the Trisomy 21 disorder and will be born with Down syndrome, it can be a very scary and emotional time. Women in this situation deserve easy access the correct information in order to help them make an informed decision based on their own choice and not the opinion of someone else.

ContributorsFitzgerald, Grace (Author) / Maienschein, Jane (Thesis director) / Ziganshina, Dina (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2022-05