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Electrical neural activity detection and tracking have many applications in medical research and brain computer interface technologies. In this thesis, we focus on the development of advanced signal processing algorithms to track neural activity and on the mapping of these algorithms onto hardware to enable real-time tracking. At the heart

Electrical neural activity detection and tracking have many applications in medical research and brain computer interface technologies. In this thesis, we focus on the development of advanced signal processing algorithms to track neural activity and on the mapping of these algorithms onto hardware to enable real-time tracking. At the heart of these algorithms is particle filtering (PF), a sequential Monte Carlo technique used to estimate the unknown parameters of dynamic systems. First, we analyze the bottlenecks in existing PF algorithms, and we propose a new parallel PF (PPF) algorithm based on the independent Metropolis-Hastings (IMH) algorithm. We show that the proposed PPF-IMH algorithm improves the root mean-squared error (RMSE) estimation performance, and we demonstrate that a parallel implementation of the algorithm results in significant reduction in inter-processor communication. We apply our implementation on a Xilinx Virtex-5 field programmable gate array (FPGA) platform to demonstrate that, for a one-dimensional problem, the PPF-IMH architecture with four processing elements and 1,000 particles can process input samples at 170 kHz by using less than 5% FPGA resources. We also apply the proposed PPF-IMH to waveform-agile sensing to achieve real-time tracking of dynamic targets with high RMSE tracking performance. We next integrate the PPF-IMH algorithm to track the dynamic parameters in neural sensing when the number of neural dipole sources is known. We analyze the computational complexity of a PF based method and propose the use of multiple particle filtering (MPF) to reduce the complexity. We demonstrate the improved performance of MPF using numerical simulations with both synthetic and real data. We also propose an FPGA implementation of the MPF algorithm and show that the implementation supports real-time tracking. For the more realistic scenario of automatically estimating an unknown number of time-varying neural dipole sources, we propose a new approach based on the probability hypothesis density filtering (PHDF) algorithm. The PHDF is implemented using particle filtering (PF-PHDF), and it is applied in a closed-loop to first estimate the number of dipole sources and then their corresponding amplitude, location and orientation parameters. We demonstrate the improved tracking performance of the proposed PF-PHDF algorithm and map it onto a Xilinx Virtex-5 FPGA platform to show its real-time implementation potential. Finally, we propose the use of sensor scheduling and compressive sensing techniques to reduce the number of active sensors, and thus overall power consumption, of electroencephalography (EEG) systems. We propose an efficient sensor scheduling algorithm which adaptively configures EEG sensors at each measurement time interval to reduce the number of sensors needed for accurate tracking. We combine the sensor scheduling method with PF-PHDF and implement the system on an FPGA platform to achieve real-time tracking. We also investigate the sparsity of EEG signals and integrate compressive sensing with PF to estimate neural activity. Simulation results show that both sensor scheduling and compressive sensing based methods achieve comparable tracking performance with significantly reduced number of sensors.
ContributorsMiao, Lifeng (Author) / Chakrabarti, Chaitali (Thesis advisor) / Papandreou-Suppappola, Antonia (Thesis advisor) / Zhang, Junshan (Committee member) / Bliss, Daniel (Committee member) / Kovvali, Narayan (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The use of electromyography (EMG) signals to characterize muscle fatigue has been widely accepted. Initial work on characterizing muscle fatigue during isometric contractions demonstrated that its frequency decreases while its amplitude increases with the onset of fatigue. More recent work concentrated on developing techniques to characterize dynamic contractions for use

The use of electromyography (EMG) signals to characterize muscle fatigue has been widely accepted. Initial work on characterizing muscle fatigue during isometric contractions demonstrated that its frequency decreases while its amplitude increases with the onset of fatigue. More recent work concentrated on developing techniques to characterize dynamic contractions for use in clinical and training applications. Studies demonstrated that as fatigue progresses, the EMG signal undergoes a shift in frequency, and different physiological mechanisms on the possible cause of the shift were considered. Time-frequency processing, using the Wigner distribution or spectrogram, is one of the techniques used to estimate the instantaneous mean frequency and instantaneous median frequency of the EMG signal using a variety of techniques. However, these time-frequency methods suffer either from cross-term interference when processing signals with multiple components or time-frequency resolution due to the use of windowing. This study proposes the use of the matching pursuit decomposition (MPD) with a Gaussian dictionary to process EMG signals produced during both isometric and dynamic contractions. In particular, the MPD obtains unique time-frequency features that represent the EMG signal time-frequency dependence without suffering from cross-terms or loss in time-frequency resolution. As the MPD does not depend on an analysis window like the spectrogram, it is more robust in applying the timefrequency features to identify the spectral time-variation of the EGM signal.
ContributorsAustin, Hiroko (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Kovvali, Narayan (Committee member) / Muthuswamy, Jitendran (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Advancements in computer vision and machine learning have added a new dimension to remote sensing applications with the aid of imagery analysis techniques. Applications such as autonomous navigation and terrain classification which make use of image classification techniques are challenging problems and research is still being carried out to find

Advancements in computer vision and machine learning have added a new dimension to remote sensing applications with the aid of imagery analysis techniques. Applications such as autonomous navigation and terrain classification which make use of image classification techniques are challenging problems and research is still being carried out to find better solutions. In this thesis, a novel method is proposed which uses image registration techniques to provide better image classification. This method reduces the error rate of classification by performing image registration of the images with the previously obtained images before performing classification. The motivation behind this is the fact that images that are obtained in the same region which need to be classified will not differ significantly in characteristics. Hence, registration will provide an image that matches closer to the previously obtained image, thus providing better classification. To illustrate that the proposed method works, naïve Bayes and iterative closest point (ICP) algorithms are used for the image classification and registration stages respectively. This implementation was tested extensively in simulation using synthetic images and using a real life data set called the Defense Advanced Research Project Agency (DARPA) Learning Applied to Ground Robots (LAGR) dataset. The results show that the ICP algorithm does help in better classification with Naïve Bayes by reducing the error rate by an average of about 10% in the synthetic data and by about 7% on the actual datasets used.
ContributorsMuralidhar, Ashwini (Author) / Saripalli, Srikanth (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Turaga, Pavan (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Research on developing new algorithms to improve information on brain functionality and structure is ongoing. Studying neural activity through dipole source localization with electroencephalography (EEG) and magnetoencephalography (MEG) sensor measurements can lead to diagnosis and treatment of a brain disorder and can also identify the area of the brain from

Research on developing new algorithms to improve information on brain functionality and structure is ongoing. Studying neural activity through dipole source localization with electroencephalography (EEG) and magnetoencephalography (MEG) sensor measurements can lead to diagnosis and treatment of a brain disorder and can also identify the area of the brain from where the disorder has originated. Designing advanced localization algorithms that can adapt to environmental changes is considered a significant shift from manual diagnosis which is based on the knowledge and observation of the doctor, to an adaptive and improved brain disorder diagnosis as these algorithms can track activities that might not be noticed by the human eye. An important consideration of these localization algorithms, however, is to try and minimize the overall power consumption in order to improve the study and treatment of brain disorders. This thesis considers the problem of estimating dynamic parameters of neural dipole sources while minimizing the system's overall power consumption; this is achieved by minimizing the number of EEG/MEG measurements sensors without a loss in estimation performance accuracy. As the EEG/MEG measurements models are related non-linearity to the dipole source locations and moments, these dynamic parameters can be estimated using sequential Monte Carlo methods such as particle filtering. Due to the large number of sensors required to record EEG/MEG Measurements for use in the particle filter, over long period recordings, a large amounts of power is required for storage and transmission. In order to reduce the overall power consumption, two methods are proposed. The first method used the predicted mean square estimation error as the performance metric under the constraint of a maximum power consumption. The performance metric of the second method uses the distance between the location of the sensors and the location estimate of the dipole source at the previous time step; this sensor scheduling scheme results in maximizing the overall signal-to-noise ratio. The performance of both methods is demonstrated using simulated data, and both methods show that they can provide good estimation results with significant reduction in the number of activated sensors at each time step.
ContributorsMichael, Stefanos (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Chakrabarti, Chaitali (Committee member) / Kovvali, Narayan (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision: including view-point in activity analysis, articulation in shape analysis, and measurement invariance in non-linear dynamical modeling. The increasing success of these methods is attributed to the complementary information that topology provides, as well

Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision: including view-point in activity analysis, articulation in shape analysis, and measurement invariance in non-linear dynamical modeling. The increasing success of these methods is attributed to the complementary information that topology provides, as well as availability of tools for computing topological summaries such as persistence diagrams. However, persistence diagrams are multi-sets of points and hence it is not straightforward to fuse them with features used for contemporary machine learning tools like deep-nets. In this paper theoretically well-grounded approaches to develop novel perturbation robust topological representations are presented, with the long-term view of making them amenable to fusion with contemporary learning architectures. The proposed representation lives on a Grassmann manifold and hence can be efficiently used in machine learning pipelines.

The proposed representation.The efficacy of the proposed descriptor was explored on three applications: view-invariant activity analysis, 3D shape analysis, and non-linear dynamical modeling. Favorable results in both high-level recognition performance and improved performance in reduction of time-complexity when compared to other baseline methods are obtained.
ContributorsThopalli, Kowshik (Author) / Turaga, Pavan Kumar (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Yang, Yezhou (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Deep learning architectures have been widely explored in computer vision and have

depicted commendable performance in a variety of applications. A fundamental challenge

in training deep networks is the requirement of large amounts of labeled training

data. While gathering large quantities of unlabeled data is cheap and easy, annotating

the data is an expensive

Deep learning architectures have been widely explored in computer vision and have

depicted commendable performance in a variety of applications. A fundamental challenge

in training deep networks is the requirement of large amounts of labeled training

data. While gathering large quantities of unlabeled data is cheap and easy, annotating

the data is an expensive process in terms of time, labor and human expertise.

Thus, developing algorithms that minimize the human effort in training deep models

is of immense practical importance. Active learning algorithms automatically identify

salient and exemplar samples from large amounts of unlabeled data and can augment

maximal information to supervised learning models, thereby reducing the human annotation

effort in training machine learning models. The goal of this dissertation is to

fuse ideas from deep learning and active learning and design novel deep active learning

algorithms. The proposed learning methodologies explore diverse label spaces to

solve different computer vision applications. Three major contributions have emerged

from this work; (i) a deep active framework for multi-class image classication, (ii)

a deep active model with and without label correlation for multi-label image classi-

cation and (iii) a deep active paradigm for regression. Extensive empirical studies

on a variety of multi-class, multi-label and regression vision datasets corroborate the

potential of the proposed methods for real-world applications. Additional contributions

include: (i) a multimodal emotion database consisting of recordings of facial

expressions, body gestures, vocal expressions and physiological signals of actors enacting

various emotions, (ii) four multimodal deep belief network models and (iii)

an in-depth analysis of the effect of transfer of multimodal emotion features between

source and target networks on classification accuracy and training time. These related

contributions help comprehend the challenges involved in training deep learning

models and motivate the main goal of this dissertation.
ContributorsRanganathan, Hiranmayi (Author) / Sethuraman, Panchanathan (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Li, Baoxin (Committee member) / Chakraborty, Shayok (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Tracking targets in the presence of clutter is inevitable, and presents many challenges. Additionally, rapid, drastic changes in clutter density between different environments or scenarios can make it even more difficult for tracking algorithms to adapt. A novel approach to target tracking in such dynamic clutter environments is proposed using

Tracking targets in the presence of clutter is inevitable, and presents many challenges. Additionally, rapid, drastic changes in clutter density between different environments or scenarios can make it even more difficult for tracking algorithms to adapt. A novel approach to target tracking in such dynamic clutter environments is proposed using a particle filter (PF) integrated with Interacting Multiple Models (IMMs) to compensate and adapt to the transition between different clutter densities. This model was implemented for the case of a monostatic sensor tracking a single target moving with constant velocity along a two-dimensional trajectory, which crossed between regions of drastically different clutter densities. Multiple combinations of clutter density transitions were considered, using up to three different clutter densities. It was shown that the integrated IMM PF algorithm outperforms traditional approaches such as the PF in terms of tracking results and performance. The minimal additional computational expense of including the IMM more than warrants the benefits of having it supplement and amplify the advantages of the PF.
ContributorsDutson, Karl (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Kovvali, Narayan (Committee member) / Bliss, Daniel W (Committee member) / Arizona State University (Publisher)
Created2015
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Description
The increased risk of falling and the worse ability to perform other daily physical activities in the elderly cause concern about monitoring and correcting basic everyday movement. In this thesis, a Kinect-based system was designed to assess one of the most important factors in balance control of human body when

The increased risk of falling and the worse ability to perform other daily physical activities in the elderly cause concern about monitoring and correcting basic everyday movement. In this thesis, a Kinect-based system was designed to assess one of the most important factors in balance control of human body when doing Sit-to-Stand (STS) movement: the postural symmetry in mediolateral direction. A symmetry score, calculated by the data obtained from a Kinect RGB-D camera, was proposed to reflect the mediolateral postural symmetry degree and was used to drive a real-time audio feedback designed in MAX/MSP to help users adjust themselves to perform their movement in a more symmetrical way during STS. The symmetry score was verified by calculating the Spearman correlation coefficient with the data obtained from Inertial Measurement Unit (IMU) sensor and got an average value at 0.732. Five healthy adults, four males and one female, with normal balance abilities and with no musculoskeletal disorders, were selected to participate in the experiment and the results showed that the low-cost Kinect-based system has the potential to train users to perform a more symmetrical movement in mediolateral direction during STS movement.
ContributorsZhou, Henghao (Author) / Turaga, Pavan (Thesis advisor) / Ingalls, Todd (Committee member) / Papandreou-Suppappola, Antonia (Committee member) / Arizona State University (Publisher)
Created2016
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Description
In the last 15 years, there has been a significant increase in the number of motor neural prostheses used for restoring limb function lost due to neurological disorders or accidents. The aim of this technology is to enable patients to control a motor prosthesis using their residual neural pathways (central

In the last 15 years, there has been a significant increase in the number of motor neural prostheses used for restoring limb function lost due to neurological disorders or accidents. The aim of this technology is to enable patients to control a motor prosthesis using their residual neural pathways (central or peripheral). Recent studies in non-human primates and humans have shown the possibility of controlling a prosthesis for accomplishing varied tasks such as self-feeding, typing, reaching, grasping, and performing fine dexterous movements. A neural decoding system comprises mainly of three components: (i) sensors to record neural signals, (ii) an algorithm to map neural recordings to upper limb kinematics and (iii) a prosthetic arm actuated by control signals generated by the algorithm. Machine learning algorithms that map input neural activity to the output kinematics (like finger trajectory) form the core of the neural decoding system. The choice of the algorithm is thus, mainly imposed by the neural signal of interest and the output parameter being decoded. The various parts of a neural decoding system are neural data, feature extraction, feature selection, and machine learning algorithm. There have been significant advances in the field of neural prosthetic applications. But there are challenges for translating a neural prosthesis from a laboratory setting to a clinical environment. To achieve a fully functional prosthetic device with maximum user compliance and acceptance, these factors need to be addressed and taken into consideration. Three challenges in developing robust neural decoding systems were addressed by exploring neural variability in the peripheral nervous system for dexterous finger movements, feature selection methods based on clinically relevant metrics and a novel method for decoding dexterous finger movements based on ensemble methods.
ContributorsPadmanaban, Subash (Author) / Greger, Bradley (Thesis advisor) / Santello, Marco (Committee member) / Helms Tillery, Stephen (Committee member) / Papandreou-Suppappola, Antonia (Committee member) / Crook, Sharon (Committee member) / Arizona State University (Publisher)
Created2017
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Description
The exponential rise in unmanned aerial vehicles has necessitated the need for accurate pose estimation under any extreme conditions. Visual Odometry (VO) is the estimation of position and orientation of a vehicle based on analysis of a sequence of images captured from a camera mounted on it. VO offers a

The exponential rise in unmanned aerial vehicles has necessitated the need for accurate pose estimation under any extreme conditions. Visual Odometry (VO) is the estimation of position and orientation of a vehicle based on analysis of a sequence of images captured from a camera mounted on it. VO offers a cheap and relatively accurate alternative to conventional odometry techniques like wheel odometry, inertial measurement systems and global positioning system (GPS). This thesis implements and analyzes the performance of a two camera based VO called Stereo based visual odometry (SVO) in presence of various deterrent factors like shadows, extremely bright outdoors, wet conditions etc... To allow the implementation of VO on any generic vehicle, a discussion on porting of the VO algorithm to android handsets is presented too. The SVO is implemented in three steps. In the first step, a dense disparity map for a scene is computed. To achieve this we utilize sum of absolute differences technique for stereo matching on rectified and pre-filtered stereo frames. Epipolar geometry is used to simplify the matching problem. The second step involves feature detection and temporal matching. Feature detection is carried out by Harris corner detector. These features are matched between two consecutive frames using the Lucas-Kanade feature tracker. The 3D co-ordinates of these matched set of features are computed from the disparity map obtained from the first step and are mapped into each other by a translation and a rotation. The rotation and translation is computed using least squares minimization with the aid of Singular Value Decomposition. Random Sample Consensus (RANSAC) is used for outlier detection. This comprises the third step. The accuracy of the algorithm is quantified based on the final position error, which is the difference between the final position computed by the SVO algorithm and the final ground truth position as obtained from the GPS. The SVO showed an error of around 1% under normal conditions for a path length of 60 m and around 3% in bright conditions for a path length of 130 m. The algorithm suffered in presence of shadows and vibrations, with errors of around 15% and path lengths of 20 m and 100 m respectively.
ContributorsDhar, Anchit (Author) / Saripalli, Srikanth (Thesis advisor) / Li, Baoxin (Committee member) / Papandreou-Suppappola, Antonia (Committee member) / Arizona State University (Publisher)
Created2010