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Individual differences in working memory capacity partly arise from variability in attention control, a process influenced by negative emotional content. Thus, individual differences in working memory capacity should be predictive of differences in the ability to regulate attention in emotional contexts. To address this hypothesis, a complex-span working memory task

Individual differences in working memory capacity partly arise from variability in attention control, a process influenced by negative emotional content. Thus, individual differences in working memory capacity should be predictive of differences in the ability to regulate attention in emotional contexts. To address this hypothesis, a complex-span working memory task (symmetry span) was modified so that negative arousing images or neutral images subtended the background during the encoding phase. Across three experiments, negative arousing images impaired working memory encoding relative to neutral images, resulting in impoverished symmetry span scores. Additionally, in Experiment 3, both negative and arousing images captured attention and led to increased hit rates in a subsequent recognition task. Contrary to the primary hypothesis, individual differences in working memory capacity derived from three complex span tasks failed to moderate the effect of negative arousing images on working memory encoding across two large scale studies. Implications for theories of working memory and attention control in emotional contexts will be discussed.
ContributorsWingert, Kimberly Marie (Author) / Brewer, Gene A. (Thesis advisor) / Amazeen, Eric (Committee member) / Killeen, Peter (Committee member) / Goldinger, Stephen (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Visual attention (VA) is the study of mechanisms that allow the human visual system (HVS) to selectively process relevant visual information. This work focuses on the subjective and objective evaluation of computational VA models for the distortion-free case as well as in the presence of image distortions.



Existing VA models are

Visual attention (VA) is the study of mechanisms that allow the human visual system (HVS) to selectively process relevant visual information. This work focuses on the subjective and objective evaluation of computational VA models for the distortion-free case as well as in the presence of image distortions.



Existing VA models are traditionally evaluated by using VA metrics that quantify the match between predicted saliency and fixation data obtained from eye-tracking experiments on human observers. Though there is a considerable number of objective VA metrics, there exists no study that validates that these metrics are adequate for the evaluation of VA models. This work constructs a VA Quality (VAQ) Database by subjectively assessing the prediction performance of VA models on distortion-free images. Additionally, shortcomings in existing metrics are discussed through illustrative examples and a new metric that uses local weights based on fixation density and that overcomes these flaws, is proposed. The proposed VA metric outperforms all other popular existing metrics in terms of the correlation with subjective ratings.



In practice, the image quality is affected by a host of factors at several stages of the image processing pipeline such as acquisition, compression, and transmission. However, none of the existing studies have discussed the subjective and objective evaluation of visual saliency models in the presence of distortion. In this work, a Distortion-based Visual Attention Quality (DVAQ) subjective database is constructed to evaluate the quality of VA maps for images in the presence of distortions. For creating this database, saliency maps obtained from images subjected to various types of distortions, including blur, noise and compression, and varying levels of distortion severity are rated by human observers in terms of their visual resemblance to corresponding ground-truth fixation density maps. The performance of traditionally used as well as recently proposed VA metrics are evaluated by correlating their scores with the human subjective ratings. In addition, an objective evaluation of 20 state-of-the-art VA models is performed using the top-performing VA metrics together with a study of how the VA models’ prediction performance changes with different types and levels of distortions.
ContributorsGide, Milind Subhash (Author) / Karam, Lina J (Thesis advisor) / Abousleman, Glen (Committee member) / Li, Baoxin (Committee member) / Reisslein, Martin (Committee member) / Arizona State University (Publisher)
Created2016
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Description
Working memory capacity and fluid intelligence are important predictors of performance in educational settings. Thus, understanding the processes underlying the relation between working memory capacity and fluid intelligence is important. Three large scale individual differences experiments were conducted to determine the mechanisms underlying the relation between working memory capacity and

Working memory capacity and fluid intelligence are important predictors of performance in educational settings. Thus, understanding the processes underlying the relation between working memory capacity and fluid intelligence is important. Three large scale individual differences experiments were conducted to determine the mechanisms underlying the relation between working memory capacity and fluid intelligence. Experiments 1 and 2 were designed to assess whether individual differences in strategic behavior contribute to the variance shared between working memory capacity and fluid intelligence. In Experiment 3, competing theories for describing the underlying processes (cognitive vs. strategy) were evaluated in a comprehensive examination of potential underlying mechanisms. These data help inform existing theories about the mechanisms underlying the relation between WMC and gF. However, these data also indicate that the current theoretical model of the shared variance between WMC and gF would need to be revised to account for the data in Experiment 3. Possible sources of misfit are considered in the discussion along with a consideration of the theoretical implications of observing those relations in the Experiment 3 data.
ContributorsWingert, Kimberly Marie (Author) / Brewer, Gene A. (Thesis advisor) / McNamara, Danielle (Thesis advisor) / McClure, Samuel (Committee member) / Redick, Thomas (Committee member) / Arizona State University (Publisher)
Created2018
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Description
T-cells are an integral component of the immune system, enabling the body to distinguish between pathogens and the self. The primary mechanism which enables this is their T-cell receptors (TCR) which bind to antigen epitopes foreign to the body. This detection mechanism allows the T-cell to determine when an immune

T-cells are an integral component of the immune system, enabling the body to distinguish between pathogens and the self. The primary mechanism which enables this is their T-cell receptors (TCR) which bind to antigen epitopes foreign to the body. This detection mechanism allows the T-cell to determine when an immune response is necessary. The computational prediction of TCR-epitope binding is important to researchers for both medical applications and for furthering their understanding of the biological mechanisms that impact immunity. Models which have been developed for this purpose fail to account for the interrelationships between amino acids and demonstrate poor out-of-sample performance. Small changes to the amino acids in these protein sequences can drastically change their structure and function. In recent years, attention-based deep learning models have shown success in their ability to learn rich contextual representations of data. To capture the contextual biological relationships between the amino acids, a multi-head self-attention model was created to predict the binding affinity between given TCR and epitope sequences. By learning the structural nuances of the sequences, this model is able to improve upon existing model performance and grant insights into the underlying mechanisms which impact binding.
ContributorsCai, Michael Ray (Author) / Lee, Heewook (Thesis advisor) / Bang, Seojin (Committee member) / Baral, Chitta (Committee member) / Arizona State University (Publisher)
Created2021