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Description
Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups

Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups or graphs. In this thesis, I first propose to solve a sparse learning model with a general group structure, where the predefined groups may overlap with each other. Then, I present three real world applications which can benefit from the group structured sparse learning technique. In the first application, I study the Alzheimer's Disease diagnosis problem using multi-modality neuroimaging data. In this dataset, not every subject has all data sources available, exhibiting an unique and challenging block-wise missing pattern. In the second application, I study the automatic annotation and retrieval of fruit-fly gene expression pattern images. Combined with the spatial information, sparse learning techniques can be used to construct effective representation of the expression images. In the third application, I present a new computational approach to annotate developmental stage for Drosophila embryos in the gene expression images. In addition, it provides a stage score that enables one to more finely annotate each embryo so that they are divided into early and late periods of development within standard stage demarcations. Stage scores help us to illuminate global gene activities and changes much better, and more refined stage annotations improve our ability to better interpret results when expression pattern matches are discovered between genes.
ContributorsYuan, Lei (Author) / Ye, Jieping (Thesis advisor) / Wang, Yalin (Committee member) / Xue, Guoliang (Committee member) / Kumar, Sudhir (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Multi-task learning (MTL) aims to improve the generalization performance (of the resulting classifiers) by learning multiple related tasks simultaneously. Specifically, MTL exploits the intrinsic task relatedness, based on which the informative domain knowledge from each task can be shared across multiple tasks and thus facilitate the individual task learning. It

Multi-task learning (MTL) aims to improve the generalization performance (of the resulting classifiers) by learning multiple related tasks simultaneously. Specifically, MTL exploits the intrinsic task relatedness, based on which the informative domain knowledge from each task can be shared across multiple tasks and thus facilitate the individual task learning. It is particularly desirable to share the domain knowledge (among the tasks) when there are a number of related tasks but only limited training data is available for each task. Modeling the relationship of multiple tasks is critical to the generalization performance of the MTL algorithms. In this dissertation, I propose a series of MTL approaches which assume that multiple tasks are intrinsically related via a shared low-dimensional feature space. The proposed MTL approaches are developed to deal with different scenarios and settings; they are respectively formulated as mathematical optimization problems of minimizing the empirical loss regularized by different structures. For all proposed MTL formulations, I develop the associated optimization algorithms to find their globally optimal solution efficiently. I also conduct theoretical analysis for certain MTL approaches by deriving the globally optimal solution recovery condition and the performance bound. To demonstrate the practical performance, I apply the proposed MTL approaches on different real-world applications: (1) Automated annotation of the Drosophila gene expression pattern images; (2) Categorization of the Yahoo web pages. Our experimental results demonstrate the efficiency and effectiveness of the proposed algorithms.
ContributorsChen, Jianhui (Author) / Ye, Jieping (Thesis advisor) / Kumar, Sudhir (Committee member) / Liu, Huan (Committee member) / Xue, Guoliang (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Sparse learning is a technique in machine learning for feature selection and dimensionality reduction, to find a sparse set of the most relevant features. In any machine learning problem, there is a considerable amount of irrelevant information, and separating relevant information from the irrelevant information has been a topic of

Sparse learning is a technique in machine learning for feature selection and dimensionality reduction, to find a sparse set of the most relevant features. In any machine learning problem, there is a considerable amount of irrelevant information, and separating relevant information from the irrelevant information has been a topic of focus. In supervised learning like regression, the data consists of many features and only a subset of the features may be responsible for the result. Also, the features might require special structural requirements, which introduces additional complexity for feature selection. The sparse learning package, provides a set of algorithms for learning a sparse set of the most relevant features for both regression and classification problems. Structural dependencies among features which introduce additional requirements are also provided as part of the package. The features may be grouped together, and there may exist hierarchies and over- lapping groups among these, and there may be requirements for selecting the most relevant groups among them. In spite of getting sparse solutions, the solutions are not guaranteed to be robust. For the selection to be robust, there are certain techniques which provide theoretical justification of why certain features are selected. The stability selection, is a method for feature selection which allows the use of existing sparse learning methods to select the stable set of features for a given training sample. This is done by assigning probabilities for the features: by sub-sampling the training data and using a specific sparse learning technique to learn the relevant features, and repeating this a large number of times, and counting the probability as the number of times a feature is selected. Cross-validation which is used to determine the best parameter value over a range of values, further allows to select the best parameter value. This is done by selecting the parameter value which gives the maximum accuracy score. With such a combination of algorithms, with good convergence guarantees, stable feature selection properties and the inclusion of various structural dependencies among features, the sparse learning package will be a powerful tool for machine learning research. Modular structure, C implementation, ATLAS integration for fast linear algebraic subroutines, make it one of the best tool for a large sparse setting. The varied collection of algorithms, support for group sparsity, batch algorithms, are a few of the notable functionality of the SLEP package, and these features can be used in a variety of fields to infer relevant elements. The Alzheimer Disease(AD) is a neurodegenerative disease, which gradually leads to dementia. The SLEP package is used for feature selection for getting the most relevant biomarkers from the available AD dataset, and the results show that, indeed, only a subset of the features are required to gain valuable insights.
ContributorsThulasiram, Ramesh (Author) / Ye, Jieping (Thesis advisor) / Xue, Guoliang (Committee member) / Sen, Arunabha (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Discriminative learning when training and test data belong to different distributions is a challenging and complex task. Often times we have very few or no labeled data from the test or target distribution, but we may have plenty of labeled data from one or multiple related sources with different distributions.

Discriminative learning when training and test data belong to different distributions is a challenging and complex task. Often times we have very few or no labeled data from the test or target distribution, but we may have plenty of labeled data from one or multiple related sources with different distributions. Due to its capability of migrating knowledge from related domains, transfer learning has shown to be effective for cross-domain learning problems. In this dissertation, I carry out research along this direction with a particular focus on designing efficient and effective algorithms for BioImaging and Bilingual applications. Specifically, I propose deep transfer learning algorithms which combine transfer learning and deep learning to improve image annotation performance. Firstly, I propose to generate the deep features for the Drosophila embryo images via pretrained deep models and build linear classifiers on top of the deep features. Secondly, I propose to fine-tune the pretrained model with a small amount of labeled images. The time complexity and performance of deep transfer learning methodologies are investigated. Promising results have demonstrated the knowledge transfer ability of proposed deep transfer algorithms. Moreover, I propose a novel Robust Principal Component Analysis (RPCA) approach to process the noisy images in advance. In addition, I also present a two-stage re-weighting framework for general domain adaptation problems. The distribution of source domain is mapped towards the target domain in the first stage, and an adaptive learning model is proposed in the second stage to incorporate label information from the target domain if it is available. Then the proposed model is applied to tackle cross lingual spam detection problem at LinkedIn’s website. Our experimental results on real data demonstrate the efficiency and effectiveness of the proposed algorithms.
ContributorsSun, Qian (Author) / Ye, Jieping (Committee member) / Xue, Guoliang (Committee member) / Liu, Huan (Committee member) / Li, Jing (Committee member) / Arizona State University (Publisher)
Created2015
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Description
With the advent of Internet, the data being added online is increasing at enormous rate. Though search engines are using IR techniques to facilitate the search requests from users, the results are not effective towards the search query of the user. The search engine user has to go through certain

With the advent of Internet, the data being added online is increasing at enormous rate. Though search engines are using IR techniques to facilitate the search requests from users, the results are not effective towards the search query of the user. The search engine user has to go through certain webpages before getting at the webpage he/she wanted. This problem of Information Overload can be solved using Automatic Text Summarization. Summarization is a process of obtaining at abridged version of documents so that user can have a quick view to understand what exactly the document is about. Email threads from W3C are used in this system. Apart from common IR features like Term Frequency, Inverse Document Frequency, Term Rank, a variation of page rank based on graph model, which can cluster the words with respective to word ambiguity, is implemented. Term Rank also considers the possibility of co-occurrence of words with the corpus and evaluates the rank of the word accordingly. Sentences of email threads are ranked as per features and summaries are generated. System implemented the concept of pyramid evaluation in content selection. The system can be considered as a framework for Unsupervised Learning in text summarization.
ContributorsNadella, Sravan (Author) / Davulcu, Hasan (Thesis advisor) / Li, Baoxin (Committee member) / Sen, Arunabha (Committee member) / Arizona State University (Publisher)
Created2015
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Description
This research start utilizing an efficient sparse inverse covariance matrix (precision matrix) estimation technique to identify a set of highly correlated discriminative perspectives between radical and counter-radical groups. A ranking system has been developed that utilizes ranked perspectives to map Islamic organizations on a set of socio-cultural, political and behavioral

This research start utilizing an efficient sparse inverse covariance matrix (precision matrix) estimation technique to identify a set of highly correlated discriminative perspectives between radical and counter-radical groups. A ranking system has been developed that utilizes ranked perspectives to map Islamic organizations on a set of socio-cultural, political and behavioral scales based on their web site corpus. Simultaneously, a gold standard ranking of these organizations was created through domain experts and compute expert-to-expert agreements and present experimental results comparing the performance of the QUIC based scaling system to another baseline method for organizations. The QUIC based algorithm not only outperforms the baseline methods, but it is also the only system that consistently performs at area expert-level accuracies for all scales. Also, a multi-scale ideological model has been developed and it investigates the correlates of Islamic extremism in Indonesia, Nigeria and UK. This analysis demonstrate that violence does not correlate strongly with broad Muslim theological or sectarian orientations; it shows that religious diversity intolerance is the only consistent and statistically significant ideological correlate of Islamic extremism in these countries, alongside desire for political change in UK and Indonesia, and social change in Nigeria. Next, dynamic issues and communities tracking system based on NMF(Non-negative Matrix Factorization) co-clustering algorithm has been built to better understand the dynamics of virtual communities. The system used between Iran and Saudi Arabia to build and apply a multi-party agent-based model that can demonstrate the role of wedges and spoilers in a complex environment where coalitions are dynamic. Lastly, a visual intelligence platform for tracking the diffusion of online social movements has been developed called LookingGlass to track the geographical footprint, shifting positions and flows of individuals, topics and perspectives between groups. The algorithm utilize large amounts of text collected from a wide variety of organizations’ media outlets to discover their hotly debated topics, and their discriminative perspectives voiced by opposing camps organized into multiple scales. Discriminating perspectives is utilized to classify and map individual Tweeter’s message content to social movements based on the perspectives expressed in their tweets.
ContributorsKim, Nyunsu (Author) / Davulcu, Hasan (Thesis advisor) / Sen, Arunabha (Committee member) / Hsiao, Sharon (Committee member) / Corman, Steven (Committee member) / Arizona State University (Publisher)
Created2018
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Description
In supervised learning, machine learning techniques can be applied to learn a model on

a small set of labeled documents which can be used to classify a larger set of unknown

documents. Machine learning techniques can be used to analyze a political scenario

in a given society. A lot of research has been

In supervised learning, machine learning techniques can be applied to learn a model on

a small set of labeled documents which can be used to classify a larger set of unknown

documents. Machine learning techniques can be used to analyze a political scenario

in a given society. A lot of research has been going on in this field to understand

the interactions of various people in the society in response to actions taken by their

organizations.

This paper talks about understanding the Russian influence on people in Latvia.

This is done by building an eeffective model learnt on initial set of documents

containing a combination of official party web-pages, important political leaders' social

networking sites. Since twitter is a micro-blogging site which allows people to post

their opinions on any topic, the model built is used for estimating the tweets sup-

porting the Russian and Latvian political organizations in Latvia. All the documents

collected for analysis are in Latvian and Russian languages which are rich in vocabulary resulting into huge number of features. Hence, feature selection techniques can

be used to reduce the vocabulary set relevant to the classification model. This thesis

provides a comparative analysis of traditional feature selection techniques and implementation of a new iterative feature selection method using EM and cross-domain

training along with supportive visualization tool. This method out performed other

feature selection methods by reducing the number of features up-to 50% along with

good model accuracy. The results from the classification are used to interpret user

behavior and their political influence patterns across organizations in Latvia using

interactive dashboard with combination of powerful widgets.
ContributorsBollapragada, Lakshmi Gayatri Niharika (Author) / Davulcu, Hasan (Thesis advisor) / Sen, Arunabha (Committee member) / Hsiao, Ihan (Committee member) / Arizona State University (Publisher)
Created2016
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Description
Passwords are ubiquitous and are poised to stay that way due to their relative usability, security and deployability when compared with alternative authentication schemes. Unfortunately, humans struggle with some of the assumptions or requirements that are necessary for truly strong passwords. As administrators try to push users towards password complexity

Passwords are ubiquitous and are poised to stay that way due to their relative usability, security and deployability when compared with alternative authentication schemes. Unfortunately, humans struggle with some of the assumptions or requirements that are necessary for truly strong passwords. As administrators try to push users towards password complexity and diversity, users still end up using predictable mangling patterns on old passwords and reusing the same passwords across services; users even inadvertently converge on the same patterns to a surprising degree, making an attacker’s job easier. This work explores using machine learning techniques to pick out strong passwords from weak ones, from a dataset of 10 million passwords, based on how structurally similar they were to the rest of the set.
ContributorsTodd, Margaret Nicole (Author) / Xue, Guoliang (Thesis advisor) / Ahn, Gail-Joon (Committee member) / Huang, Dijiang (Committee member) / Arizona State University (Publisher)
Created2016
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Description
Large-scale $\ell_1$-regularized loss minimization problems arise in high-dimensional applications such as compressed sensing and high-dimensional supervised learning, including classification and regression problems. In many applications, it remains challenging to apply the sparse learning model to large-scale problems that have massive data samples with high-dimensional features. One popular and promising strategy

Large-scale $\ell_1$-regularized loss minimization problems arise in high-dimensional applications such as compressed sensing and high-dimensional supervised learning, including classification and regression problems. In many applications, it remains challenging to apply the sparse learning model to large-scale problems that have massive data samples with high-dimensional features. One popular and promising strategy is to scaling up the optimization problem in parallel. Parallel solvers run multiple cores on a shared memory system or a distributed environment to speed up the computation, while the practical usage is limited by the huge dimension in the feature space and synchronization problems.

In this dissertation, I carry out the research along the direction with particular focuses on scaling up the optimization of sparse learning for supervised and unsupervised learning problems. For the supervised learning, I firstly propose an asynchronous parallel solver to optimize the large-scale sparse learning model in a multithreading environment. Moreover, I propose a distributed framework to conduct the learning process when the dataset is distributed stored among different machines. Then the proposed model is further extended to the studies of risk genetic factors for Alzheimer's Disease (AD) among different research institutions, integrating a group feature selection framework to rank the top risk SNPs for AD. For the unsupervised learning problem, I propose a highly efficient solver, termed Stochastic Coordinate Coding (SCC), scaling up the optimization of dictionary learning and sparse coding problems. The common issue for the medical imaging research is that the longitudinal features of patients among different time points are beneficial to study together. To further improve the dictionary learning model, I propose a multi-task dictionary learning method, learning the different task simultaneously and utilizing shared and individual dictionary to encode both consistent and changing imaging features.
ContributorsLi, Qingyang (Author) / Ye, Jieping (Thesis advisor) / Xue, Guoliang (Thesis advisor) / He, Jingrui (Committee member) / Wang, Yalin (Committee member) / Li, Jing (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Imaging genetics is an emerging and promising technique that investigates how genetic variations affect brain development, structure, and function. By exploiting disorder-related neuroimaging phenotypes, this class of studies provides a novel direction to reveal and understand the complex genetic mechanisms. Oftentimes, imaging genetics studies are challenging due to the relatively

Imaging genetics is an emerging and promising technique that investigates how genetic variations affect brain development, structure, and function. By exploiting disorder-related neuroimaging phenotypes, this class of studies provides a novel direction to reveal and understand the complex genetic mechanisms. Oftentimes, imaging genetics studies are challenging due to the relatively small number of subjects but extremely high-dimensionality of both imaging data and genomic data. In this dissertation, I carry on my research on imaging genetics with particular focuses on two tasks---building predictive models between neuroimaging data and genomic data, and identifying disorder-related genetic risk factors through image-based biomarkers. To this end, I consider a suite of structured sparse methods---that can produce interpretable models and are robust to overfitting---for imaging genetics. With carefully-designed sparse-inducing regularizers, different biological priors are incorporated into learning models. More specifically, in the Allen brain image--gene expression study, I adopt an advanced sparse coding approach for image feature extraction and employ a multi-task learning approach for multi-class annotation. Moreover, I propose a label structured-based two-stage learning framework, which utilizes the hierarchical structure among labels, for multi-label annotation. In the Alzheimer's disease neuroimaging initiative (ADNI) imaging genetics study, I employ Lasso together with EDPP (enhanced dual polytope projections) screening rules to fast identify Alzheimer's disease risk SNPs. I also adopt the tree-structured group Lasso with MLFre (multi-layer feature reduction) screening rules to incorporate linkage disequilibrium information into modeling. Moreover, I propose a novel absolute fused Lasso model for ADNI imaging genetics. This method utilizes SNP spatial structure and is robust to the choice of reference alleles of genotype coding. In addition, I propose a two-level structured sparse model that incorporates gene-level networks through a graph penalty into SNP-level model construction. Lastly, I explore a convolutional neural network approach for accurate predicting Alzheimer's disease related imaging phenotypes. Experimental results on real-world imaging genetics applications demonstrate the efficiency and effectiveness of the proposed structured sparse methods.
ContributorsYang, Tao (Author) / Ye, Jieping (Thesis advisor) / Xue, Guoliang (Thesis advisor) / He, Jingrui (Committee member) / Li, Baoxin (Committee member) / Li, Jing (Committee member) / Arizona State University (Publisher)
Created2017