Matching Items (25)
Filtering by
- All Subjects: Creative Project
- Creators: Department of Supply Chain Management
- Status: Published
Description
500 Days of Summer, released in 2009 and written by Scott Neustadter and Michael H. Weber, is an American film told through the perspective of Tom Hansen, the male lead. It is a story that begins with a third-person narrator, explaining that “This is a story of boy meets girl.” The narration then finishes with a warning that “you should know up front, this is not a love story” (Neustadter & Weber, 2009). As the movie continues, however, it becomes increasingly challenging to believe this warning. Tom sees Summer Finn, falls in love, and their relationship ends with him broken-hearted. It is only natural for the audience to view it as a story of Tom’s failed love, and without a deeper analysis, to perceive Summer as the antagonist. <br/> This tendency to view the movie as a love story motivated me to question why the discrepancy between the beginning narration and the common audience perception occurs. My thesis addresses this discrepancy by focusing on the idea that the natural gravitation towards the belief that 500 Days of Summer is a love story exists due to the unreliable narration given by Tom Hansen throughout the movie. I wrote three songs, an interlude, a duet, and a solo, based on the themes and lead characters of the movie to help validate the warning provided in the beginning and provide a deeper insight into Summer’s version of the story.
ContributorsVan Dusen, Sydney Elizabeth (Author) / Fette, Donald (Thesis director) / Hoyt, Heather (Committee member) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor and in return control cell differentiation and proliferation. Bexarotene targets RXR homodimerization to drive transcription of tumor suppressing genes; however, adverse reactions occur simultaneously when bound to other nuclear receptors. In this study, we used novel bexarotene analogs throughout 5 iterations synthesized in the laboratory of Dr. Wagner to test for their potency and ability to bind RXR. The aim of our study is to quantitatively measure RXR homodimerization driven by bexarotene analogs using a yeast two-hybrid system. Our results suggests there to be several compounds with higher protein activity than bexarotene, particularly in generations 3.0 and 5.0. This higher affinity for RXR homodimers may help scientists identify a compound that will minimize adverse effects and toxicity of bexarotene and serve as a better cancer treatment alternative.
ContributorsSeto, David Hua (Author) / Marshall, Pamela (Thesis director) / Wagner, Carl (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
Description
Research was conducted on the topic of Arizona's Department of Emergency Management. Specifically, the research and creative project was centered on the Search and Rescue Branch of the department. The creative project covered the key aspects and elements of Search and Rescue organization, legal considerations, preparation, training, teams, and safety. These different elements heavily impact the Search and Rescue teams of Arizona. The researched information was compiled into a paper and the overall themes were used as inspiration for a series of paintings. The paintings highlight the components that were researched and presented in the written paper.
ContributorsSavala, Renae Alejandrina (Author) / Yoshioka, Carlton (Thesis director) / Kozakiewicz, Scott (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor) / Department of Supply Chain Management (Contributor)
Created2015-05
Description
The purpose of this thesis was to design a market entrance strategy for Company X to enter the microcontroller (MCU) market within the Internet of Things (IoT). The five IoT segments are automotive; medical; retail; industrial; and military, aerospace, and government. To reach a final decision, we will research the markets, analyze make versus buy scenarios, and deliver a financial analysis on the chosen strategy. Based on the potential financial benefits and compatibility with Company X's current business model, we recommend that Company X enter the automotive segment through mergers & acquisitions (M&A). After analyzing the supply chain structure of the automotive IoT, we advise Company X to acquire Freescale Semiconductor for $46.98 per share.
ContributorsBradley, Rachel (Co-author) / Fankhauser, Elisa (Co-author) / McCoach, Robert (Co-author) / Zheng, Weilin (Co-author) / Simonson, Mark (Thesis director) / Hertzel, Mike (Committee member) / Barrett, The Honors College (Contributor) / Department of Finance (Contributor) / Department of Supply Chain Management (Contributor) / School of Accountancy (Contributor) / School of International Letters and Cultures (Contributor) / WPC Graduate Programs (Contributor)
Created2015-05
Description
Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective in the treatment of multiple types of cancer, including lung cancer. However, the disadvantages of using Bex include increased instances of hypothyroidism and excessive concentrations of blood triglycerides. If an analog of Bex can be developed which retains high affinity RXR binding similar to the 9-cis retinoic acid while exhibiting less interference for heterodimerization pathways, it would be of great clinical significance in improving the quality of life for patients with CTCL. This thesis will detail the biological profiling of additional novel (Generation Two) analogs, which are currently in submission for publication, as well as that of Generation Three analogs. The results from these studies reveal that specific alterations in the core structure of the Bex "parent" compound structure can have dramatic effects in modifying the biological activity of RXR agonists.
ContributorsYang, Joanna (Author) / Jurutka, Peter (Thesis director) / Wagner, Carl (Committee member) / Hibler, Elizabeth (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
Description
This thesis, entitled "A Community Perspective on Alcohol Education," was conducted over a ten month period during the Spring 2014 and Fall 2014 semesters, composed by Christopher Stuller and Nicholas Schmitzer. The research involved interviewing twelve professionals from Arizona State University and the City of Tempe to gather a holistic view on alcohol education and alcohol safety as it involves the students at ASU. Upon completion of the interviews, recommendations were made regarding areas of improvement for alcohol education and alcohol safety at Arizona State University. These recommendations range from creating a mandatory alcohol education class to passing a Guardian Angel Law to creating a national network of alcohol education best practices. Through this thesis, the authors hope to prevent future alcohol related injuries, deaths, and tragedies. For the final display of this thesis a website was created. For the ease of reading, all information has been presented in text format.
ContributorsSchmitzer, Nicholas (Co-author) / Stuller, Christopher (Co-author) / Koretz, Lora (Thesis director) / Scott Lynch, Jacquelyn (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor) / School of Accountancy (Contributor) / Department of Supply Chain Management (Contributor)
Created2014-12
Description
Upon investigating the current state of the high scrap problem at Niagara Bottling's Phoenix manufacturing facility, it was found that 49% of the scrap was being generated at the bottling lines in the form of plastic bottles, and 39% of scrap took the form of preforms accumulated at either the bottling lines or the injection molding machines. The scope of this project includes all forms of polyethylene terephthalate (PET), but the large accumulation of scrap in these areas suggests a primary focus on the bottling lines and the injection molding machines. Further analysis of the bottling lines found that the filler at each line as well as the blower on line X1 were the biggest contributors to the scrap accumulation problem. Each of these machines was seeing over 0.4% of bottles rejected at the visual inspection units. Due to the underlying status and quality issues of the injection molding machines that were beyond the scope of this project, this process was only investigated for solutions involving the overall processes and people. Based on the data and process flow analysis there were several solutions proposed including a root-cause analysis of the highest faulting machines, the repair of the injection molding overhead conveyor systems, the creation of a low waste environment, and the implementation a scrap tracking and analysis process. Based on the current high variability in the scrap experience across all machines, it is recommended that Niagara Phoenix pursue the scrap tracking and analysis alternative. After the implementing the scrap tracking and analysis process, the initial results were encouraging and could potentially warrant the investment in a software platform that could automate the collection of data necessary for this process. Based on the initial results of the manual collection and analysis process, each individual line show signs of potential reduction in the scrap rate of over 50%. According to this improvement, purchasing the software platform would see a payoff period of only 36 days.
ContributorsSanchez, Thomas Camden (Author) / Kellso, James (Thesis director) / Lupe, Munoz (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / Department of Supply Chain Management (Contributor)
Created2015-05
Description
A playwright behind the scenes of my personal struggle with PTSD, experience that caused it, and journey to healing from it. The playwright consists of deeper causes of PTSD and its effects, more than the average textbook can teach anyone. With the help of a couple people and Russ, a famous artist, I was able to grow and become stronger and show it all within my playwright. Enjoy the journey to healing of a person, a warrior who wanted to fight and made it through the night.
ContributorsCristobal, Nicky Desiree (Author) / Lewis, Stephen (Thesis director) / Zygutis, Linda (Committee member) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
This thesis aims to explain how a child can deal with loss through a children's book that I have written and illustrated. The goal is to have a child, as young as the age of seven, be able to pick up the book and come away with an initial understanding of how grief affects people. There are references to other works of literature similarly dealing with the above topic. The different stages of grief are examined, as well as the ways in which grief can be handled. Facial expressions and body language are crucial to understanding others' pain and grief, so this thesis delves into how to translate different expressions and actions, and how artwork and illustrations can portray these same ideas. The story from the book is interwoven throughout the thesis, so as to show my reasoning for each section of the text. Finally, there is a full analysis of the text as well as the illustrations that explains why the text is fitting for each section of the story.
ContributorsFauste, Cristina Maria (Author) / Lewis, Stephen (Thesis director) / Gruber, Diane (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2015-05
Description
We faced many struggles of starting college together, one of which, being the difficulty of mealtime once you are officially on your own. To the two of us and many of our friends, it was difficult no longer having a meal that felt like it turned a house to a home. Our goal of this project was to help those who may be experiencing similar feelings.
For our Thesis Project we wanted to create a cookbook that was designed specifically for college students who are living in the dorms. Our cookbook includes recipes that are low cost and easy to make for beginners. To be sure to capture our target audience, our cookbook will only included recipes which can be created using the given appliances in most standard dorms, which are limited to a microwave, blender, refrigerator and small freezer.
For the recipes specifically, we used a lot of family recipes and recipes from peers and colleagues. A great deal of time was spent actually testing out the potential recipes so we could narrow down which would be best for our book.
As two seniors who have grown immensely over the past few years at Arizona State, we recognize the issues that students may face when moving into a dorm. It was our goal to use our own experience and knowledge combined with research of those people who have also gone through this process, to create a book that we feel would have tremendously helped us navigate through our freshman year of college.
For our Thesis Project we wanted to create a cookbook that was designed specifically for college students who are living in the dorms. Our cookbook includes recipes that are low cost and easy to make for beginners. To be sure to capture our target audience, our cookbook will only included recipes which can be created using the given appliances in most standard dorms, which are limited to a microwave, blender, refrigerator and small freezer.
For the recipes specifically, we used a lot of family recipes and recipes from peers and colleagues. A great deal of time was spent actually testing out the potential recipes so we could narrow down which would be best for our book.
As two seniors who have grown immensely over the past few years at Arizona State, we recognize the issues that students may face when moving into a dorm. It was our goal to use our own experience and knowledge combined with research of those people who have also gone through this process, to create a book that we feel would have tremendously helped us navigate through our freshman year of college.
ContributorsGeorge, Grace Meredith (Co-author) / Ickes, Kamrie (Co-author) / Grgich, Traci (Thesis director) / McCoy, Maureen (Committee member) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05