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- All Subjects: Creative Project
- Creators: Harrington Bioengineering Program
- Creators: Dean, W.P. Carey School of Business
Description
Glioblastoma Multiforme (GBM) is an aggressive and deadly form of brain cancer with a median survival time of about a year with treatment. Due to the aggressive nature of these tumors and the tendency of gliomas to follow white matter tracks in the brain, each tumor mass has a unique growth pattern. Consequently it is difficult for neurosurgeons to anticipate where the tumor will spread in the brain, making treatment planning difficult. Archival patient data including MRI scans depicting the progress of tumors have been helpful in developing a model to predict Glioblastoma proliferation, but limited scans per patient make the tumor growth rate difficult to determine. Furthermore, patient treatment between scan points can significantly compound the challenge of accurately predicting the tumor growth. A partnership with Barrow Neurological Institute has allowed murine studies to be conducted in order to closely observe tumor growth and potentially improve the current model to more closely resemble intermittent stages of GBM growth without treatment effects.
ContributorsSnyder, Lena Haley (Author) / Kostelich, Eric (Thesis director) / Frakes, David (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
Motor behavior is prone to variable conditions and deviates further in disorders affecting the nervous system. A combination of environmental and neural factors impacts the amount of uncertainty. Although the influence of these factors on estimating endpoint positions have been examined, the role of limb configuration on endpoint variability has been mostly ignored. Characterizing the influence of arm configuration (i.e. intrinsic factors) would allow greater comprehension of sensorimotor integration and assist in interpreting exaggerated movement variability in patients. In this study, subjects were placed in a 3-D virtual reality environment and were asked to move from a starting position to one of three targets in the frontal plane with and without visual feedback of the moving limb. The alternating of visual feedback during trials increased uncertainty between the planning and execution phases. The starting limb configurations, adducted and abducted, were varied in separate blocks. Arm configurations were setup by rotating along the shoulder-hand axis to maintain endpoint position. The investigation hypothesized: 1) patterns of endpoint variability of movements would be dependent upon the starting arm configuration and 2) any differences observed would be more apparent in conditions that withheld visual feedback. The results indicated that there were differences in endpoint variability between arm configurations in both visual conditions, but differences in variability increased when visual feedback was withheld. Overall this suggests that in the presence of visual feedback, planning of movements in 3D space mostly uses coordinates that are arm configuration independent. On the other hand, without visual feedback, planning of movements in 3D space relies substantially on intrinsic coordinates.
ContributorsRahman, Qasim (Author) / Buneo, Christopher (Thesis director) / Helms Tillery, Stephen (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
Motor behavior is prone to variable conditions and deviates further in disorders affecting the nervous system. A combination of environmental and neural factors impacts the amount of uncertainty. Although the influence of these factors on estimating endpoint positions have been examined, the role of limb configuration on endpoint variability has been mostly ignored. Characterizing the influence of arm configuration (i.e. intrinsic factors) would allow greater comprehension of sensorimotor integration and assist in interpreting exaggerated movement variability in patients. In this study, subjects were placed in a 3-D virtual reality environment and were asked to move from a starting position to one of three targets in the frontal plane with and without visual feedback of the moving limb. The alternating of visual feedback during trials increased uncertainty between the planning and execution phases. The starting limb configurations, adducted and abducted, were varied in separate blocks. Arm configurations were setup by rotating along the shoulder-hand axis to maintain endpoint position. The investigation hypothesized: 1) patterns of endpoint variability of movements would be dependent upon the starting arm configuration and 2) any differences observed would be more apparent in conditions that withheld visual feedback. The results indicated that there were differences in endpoint variability between arm configurations in both visual conditions, but differences in variability increased when visual feedback was withheld. Overall this suggests that in the presence of visual feedback, planning of movements in 3D space mostly uses coordinates that are arm configuration independent. On the other hand, without visual feedback, planning of movements in 3D space relies substantially on intrinsic coordinates.
ContributorsRahman, Qasim (Author) / Buneo, Christopher (Thesis director) / Helms Tillery, Stephen (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
Smart contrast agents allow for noninvasive study of specific events or tissue conditions inside of a patient's body using Magnetic Resonance Imaging (MRI). This research aims to develop and characterize novel smart contrast agents for MRI that respond to temperature changes in tissue microenvironments. Transmission Electron Microscopy, Nuclear Magnetic Resonance, and cell culture growth assays were used to characterize the physical, magnetic, and cytotoxic properties of candidate nanoprobes. The nanoprobes displayed thermosensitve MR properties with decreasing relaxivity with temperature. Future work will be focused on generating and characterizing photo-active analogues of the nanoprobes that could be used for both treatment of tissues and assessment of therapy.
ContributorsHussain, Khateeb Hyder (Author) / Kodibagkar, Vikram (Thesis director) / Stabenfeldt, Sarah (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor) / School of Mathematical and Statistical Sciences (Contributor)
Created2014-05
Description
There is a wide intersection where animal and human lives interact or mimic each other behaviorally or biologically. A lot of the products that are part of our day-to-day were first validated by animals, and eventually found their way to us. From food to beauty products to scientific developments, animals deal with a lot behind the scenes. Some humans are cognizant of what is happening backstage, while others only see the final presentation. Either way, all of us have our opinions in support or against animal treatment. The project is heavily inspired from my experience in a neurorehabilitation lab, so the foundation is similar to the structure and function of neurons. Through this project, I am focusing on one aspect of this debate, which is animal testing in the scietific setting. The goal of the project is not to force the viewer to choose one side, but to understand the big picture and the reasoning of the opposing side.
ContributorsSharma, Bhavya (Author) / Beiner, Susan (Thesis director) / Roberson, Robert (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Whispers from Above is a creative project that aims to normalize the conversation and validate the emotional experience of grief, through the use of art therapies. Art therapy can be expressive in which someone creates their own work, such as visual art, poetry, performance, music, movement, etc. Art therapy can also be receptive in which someone analyzes and understands someone else's artwork. This project was released on SoundCloud in order to make grief resources more accessible to all and to build an online community.<br/><br/>Whispers from Above worked with twelve poets, fifteen artists, six different interviewees, and multiple musicians to create a month of grief support. The finale piece of Whispers from Above was devised from the twenty-nine poems used within this month-long healing journey. All the individual poems were woven into a single devised poem to be presented as the final piece symbolizing that no one is alone in grief.<br/><br/>Whispers from Above is creative community exploration of grief, loss, and death in which we hope contributors, and listeners find solace and support. This series will exist on SoundCloud after March 27th, 2021 with a monthly release of a poem or interview accompanied by art, and music.
ContributorsWendlandt, Morgan Marie (Author) / Bowditch, Rachel (Thesis director) / Lynch, John M. (Committee member) / Sandoval, Mathew (Committee member) / School of Art (Contributor) / Department of Management and Entrepreneurship (Contributor) / School of Music, Dance and Theatre (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
The goal of this project was to create a card game that would quickly and easily allow medical professionals to learn important information. This project seeks to advance ways in which medical staff gain information about disease outbreaks through the creation of a card game which teaches players the proper steps and procedure to triage and treat patients who are suspected to have Ebola Hemorrhagic Fever, which was not done properly during the recent outbreak. To create this game, research was conducted on the information given by the Center for Disease Control and Prevention (CDC) on the various steps to triaging those who were suspected of having Ebola. Various prototypes of the game were made and tested to optimize the win-lose ratio while still being an enjoyable game to play. This card game is fast-paced, small, and can be played either individually or with more than one person. It is loosely based off of Solitaire. This game has gone through three prototypes of the cards as well as a few brief testing periods. Through the methods and procedure used in this game's creation, it has been concluded that this method is a great way to easily teach players a proper procedure, and that this method of game can be applied to other disease breakouts and even to other fields where information must be learned quickly. Future steps for this game include improving the graphic art used in the cards, and continuing on to create a smartphone application.
ContributorsHenriksen, Carissa (Co-author) / Pratt, Breanna (Co-author) / LaBelle, Jeffrey (Thesis director) / Coursen, Jerry (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Descent is a modern television adaptation of Dante's Inferno, in which the main characters must navigate the levels of the Dark Web instead of Hell. This Creative Project includes the script for the first episode of this series, as well as episode summaries for each of the 10 episodes in the first season.
ContributorsSchroeder, Elizabeth Marie (Author) / Bradley, Christopher (Thesis director) / Himberg, Julia (Committee member) / Winters, Justin (Committee member) / Department of English (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
Abstract
Exploring the Veil of Blackness is a creative project in the form of a podcast titled UKME America”. UKME America stands for Uwem mi Kederimbot America, which means “my life in the world in America”. It aims to explore the differences that divide individuals within the black community from a perspective of a First-Generation African American. It also illustrates how diverse the black community is. Drawing from my own experiences and research, this led me to a common theme centered around the following four questions: (a) what is it like to lose one’s identity; (b) where does this insecurity stem from; (c) how does society impact the way we view ourselves; and (d) how can we uplift ourselves. In my podcast, I interviewed individuals who identified as African Americans, First Generation African Americans, and Africans.
Everyone I interviewed told me their stories using historical, social, and cultural narratives. Overall, I want individuals to understand that there is fluidity behind the meaning of “black”, and the more individuals learn to embrace their differences, the more we can break down the barriers, put a united front, fight societal discrimination. I would like to thank my thesis director Dr. Neveser Köker and Second Committee Chair, Matthew Voorhees. I want to thank them for their guidance, motivation, patience, and for pushing and challenging me to reach new heights. I also would like thank my mom and Dr. Cynthia Patiño, for their constant encouragement and support. This would not have been possible without them.
Exploring the Veil of Blackness is a creative project in the form of a podcast titled UKME America”. UKME America stands for Uwem mi Kederimbot America, which means “my life in the world in America”. It aims to explore the differences that divide individuals within the black community from a perspective of a First-Generation African American. It also illustrates how diverse the black community is. Drawing from my own experiences and research, this led me to a common theme centered around the following four questions: (a) what is it like to lose one’s identity; (b) where does this insecurity stem from; (c) how does society impact the way we view ourselves; and (d) how can we uplift ourselves. In my podcast, I interviewed individuals who identified as African Americans, First Generation African Americans, and Africans.
Everyone I interviewed told me their stories using historical, social, and cultural narratives. Overall, I want individuals to understand that there is fluidity behind the meaning of “black”, and the more individuals learn to embrace their differences, the more we can break down the barriers, put a united front, fight societal discrimination. I would like to thank my thesis director Dr. Neveser Köker and Second Committee Chair, Matthew Voorhees. I want to thank them for their guidance, motivation, patience, and for pushing and challenging me to reach new heights. I also would like thank my mom and Dr. Cynthia Patiño, for their constant encouragement and support. This would not have been possible without them.
ContributorsEdoh, Enyonam A (Author) / Koker, Neveser (Thesis director) / Voorhees, Matthew (Committee member) / Dean, W.P. Carey School of Business (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The Honors Creative Project evolved drastically from start to finish, despite its origin remaining the same. My core goal in this project was to connect two seemingly mutually exclusive aspects of my life, engineering and dance. After conducting an IRB study and using data from my own personal experiences, I was able to see how dance had in fact made me a better engineer. There were skills that I gained and learned in dance that were directly applicable to engineering, and I believe will be critical to my success as an engineer. As the focal point of the project angled towards myself, I had to look deeply into who I am and how I reached this point. I conducted self-reflections on various aspects of my current life and also on the struggles and hardships I overcame during my years at ASU. From these reflections, I learned a lot about myself and how my personal identity has evolved. This identity evolution became the backbone behind my thesis defense. I took my research and self-reflections and designed a series of artwork that I personally designed and painted myself. I my engineering side to conduct the research and collect the data, and then used my artistic side to present my findings to the public in a way that attracted and audience and caused others to reflect upon their own identities.
ContributorsArizmendi, Romann Fuentes (Author) / Olarte, David (Thesis director) / Welz, Matt (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05