Matching Items (25)
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- Creators: School of Molecular Sciences
Description
Same Bed is a twelve-piece book of poetry that explores the theme of sexual violence. The speaker of the poems is processing the trauma surrounding her rape which leads her to explore her own family's dynamics regarding gender, power, and acknowledgment of sexuality. The speaker also observes the broader issue of how society reacts to rape and the effects that can have on a survivor of sexual violence. In the peak of the manuscript, the speaker pieces together part of her own police report, pinning her own voice and perspective against her rapists.
ContributorsPetersen, Gabrielle Nicole (Author) / Ball, Sally (Thesis director) / Kelsey, Meghan (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Management and Entrepreneurship (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
DescriptionThis project is designed to generate enthusiasm for science among refugee students in hopes of inspiring them to continue learning science as well as to help them with their current understanding of their school science subject matter.
ContributorsSipes, Shannon Paige (Author) / O'Flaherty, Katherine (Thesis director) / Gregg, George (Committee member) / School of Molecular Sciences (Contributor) / Division of Teacher Preparation (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
Students Organize for Syria (SOS) is the student led initiative for Syria. With 18 registered chapters across the United States, this student organization is targeting a multidimensional cause by different means. Though it is now a national movement, it started off with one group at Arizona State University, with one student. Zana Alattar, founder and student director of SOS, tells the story of how she took an ASU organization, Save Our Syrian Freedom (SOS Freedom), to the national level as SOS. As a pre-medical student, she also combines her work in human rights with her future in healthcare. After all, health and human rights have long maintained a synergistic relationship.
ContributorsAlattar, Zana (Author) / Graff, Sarah (Thesis director) / McClurg, Sharolyn (Committee member) / School of Molecular Sciences (Contributor) / School of Social Transformation (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Cancer is a disease that occurs in many and perhaps all multicellular organisms. Current research is looking at how different life history characteristics among species could influence cancer rates. Because somatic maintenance is an important component of a species' life history, we hypothesize the same ecological forces shaping the life history of a species should also determine its cancer susceptibility. By looking at varying life histories, potential evolutionary trends could be used to explain differing cancer rates. Life history theory could be an important framework for understanding cancer vulnerabilities with different trade-offs between life history traits and cancer defenses. Birds have diverse life history strategies that could explain differences in cancer suppression. Peto's paradox is the observation that cancer rates do not typically increase with body size and longevity despite an increased number of cell divisions over the animal's lifetime that ought to be carcinogenic. Here we show how Peto’s paradox is negatively correlated for cancer within the clade, Aves. That is, larger, long-lived birds get more cancer than smaller, short-lived birds (p=0.0001; r2= 0.024). Sexual dimorphism in both plumage color and size differ among Aves species. We hypothesized that this could lead to a difference in cancer rates due to the amount of time and energy sexual dimorphism takes away from somatic maintenance. We tested for an association between a variety of life history traits and cancer, including reproductive potential, growth rate, incubation, mating systems, and sexual dimorphism in both color and size. We found male birds get less cancer than female birds (9.8% vs. 11.1%, p=0.0058).
ContributorsDolan, Jordyn Nicole (Author) / Maley, Carlo (Thesis director) / Harris, Valerie (Committee member) / Boddy, Amy (Committee member) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Dante's Divine Comedy has been around for eight centuries, and its imaginative vision of the afterlife truly resembled the ideology of 13th century. However, time has passed, and now, in 21st century, the societies have made major technological advancements that distinct themselves from the past. Consequently, with recent technology in mind, one could imagine an afterlife with robotic Minos and Cerberus, and possibly the circles of hell residing within an earth resembling death star that is controlled automatically using artificial intelligence. The symbolic representation of punishments could have been altered throughout time, and more recent criminals may be seen in the circles of hell. By identifying and correlating contemporary style of art with a classic literature such as Dante's Divine Comedy, one could better understand the essence of literature without the disconnect from current world, and appreciate the deep underlying ideology that Dante offers within his literature. Sculptures that encompass nine circles of hell and heaven would demonstrate structural aptitude and symbolic representation of what Dante would have imagined if he were to write his literature in the 21st century. Throughout the project, connection between the literature and the sculptures is observed. Some of the sculptures were meant to be abstract and some literal. Even though the medium used in each of the sculptures were different, the correlation between each sculpture unifies everything together into one theme, Dante's Divine Comedy.
ContributorsKim, David (Author) / Neubauer, Mary (Thesis director) / Harp, Hilary (Committee member) / School of Molecular Sciences (Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
In a cross memoir and essay format, I examine what connection barriers veterans face when communicating with civilians. I interviewed veterans after adapting an interview schedule and model release form. Additionally, I researched creative nonfiction, guided autobiography, and Posttraumatic Stress Disorder. I chose to focus mainly on soldiers returning from recent conflicts. Once I collected my interviews, I synthesized the stories I heard with personal memoir. The thesis focuses on three parts: coming home, communication barriers, and connection. Weaving in both my personal reflection and the voices of the soldiers I interviewed, I evaluate possible ways veterans and civilians fail to connect. I address the discrepancy between the apparent warm reception of soldiers and the feelings of disconnection soldiers express by noting the ways in which both the solider and the civilian struggle to communicate. Looking at reintegration struggles, I briefly note the transition difficulty post deployment soldiers face. From the responses I received, I reflect on how empty gestures, perceived ignorance, and an outsider effect contribute to communication barriers between soldiers and veterans. While I address how ignorance can be broken down into misunderstanding military jargon, detaching from war, hearing euphemisms, and having expectations, I also consider the ways in which situation and vagueness surrounding the war contribute to communication barriers surrounding perceived ignorance. From my reflection of communication barriers, I offer tools for soldiers and veterans making connections. I recommend that both soldiers and civilians stay informed about the military engagements as best they can, deconstruct expectations and generalizations, use empathy and active listening, and start being direct. Knowing the nuanced complexity of war and communication, I weave in my own reflections in contribution to the larger conversation.
ContributorsFletcher, Jessica Marie (Author) / Wells, Cornelia (Thesis director) / deLusé, Stephanie (Committee member) / Department of Psychology (Contributor) / Department of English (Contributor) / College of Letters and Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Within our current educational infrastructure, there’s a lack of substantial preventive care knowledge present among elementary schoolchildren. With education cuts occurring statewide, many schools are left impoverished and schools are incapable of implementing various programs to benefit their local communities. This endeavor aims to visit public and charter elementary schools in the Phoenix Valley to educate youth regarding easily avoidable health risks by implementing healthy eating habits and exercise. Project BandAid will immerse students ages 7-9 in hands-on activities to enhance their knowledge on hygiene, healthy eating habits, and safety. This project incorporated funding from the Woodside Community Action Grant and Barrett, the Honors College as well as the help from Alpha Epsilon Delta (AED) volunteers.
ContributorsCovarrubias, Sidney Alicia (Co-author) / Kothari, Karishma (Co-author) / John, Benson (Co-author) / Fette, Donald (Thesis director) / Holechek, Susan (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / School of Molecular Sciences (Contributor) / School for the Future of Innovation in Society (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Bodies, Sex, & Identity: Discovering Your Sexual Self is a sex education book for children ages 10 and up. This creative project is a response to the significant issues with modern sex education and the lack of resources for parents of preteens who want their children to receive accurate, inclusive, and socially responsible information about gender and sexuality. Bodies, Sex, & Identity is a pleasure-focused, sex-positive book, meant to supplement the information children receive about puberty and sex in school, on the Internet, and from other books and educational materials. The book features frequent references to sexual identity and urges its audience to reflect on how they experience their own bodies, gender, and sexuality. It contains discussion of power imbalances, stereotypes, and stigma, and it includes populations that are typically underrepresented or altogether excluded from sex education materials (specifically, intersex people, people of color, fat people, queer people, gender non-conforming people, disabled people, and asexual people). My purpose in creating Bodies, Sex, & Identity was to celebrate diversity, "fill in the gaps," and paint a more comprehensive, inclusive, and accurate picture of human sexuality.
ContributorsAndros, Natalie Rose (Author) / Katsulis, Yasmina (Thesis director) / McGibbney, Michelle (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / School of Social Transformation (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The tarot is a means of communication with the world. It allows readers to interpret signs from their surroundings, gather information, and use this information to make inferences about a posed question. Its origins can be found in mid-15th century Europe as playing cards with four suits commonly used for gambling. Several hundred years later during the 18th century, it began to be used as a tool for divination; the Major Arcana, a set of 22 trump cards representing various archetypes, evolved as a supplement to a new tarot that has become associated with mysticism. The tarot’s foundation is based on archetypes that build society. It can serve as a visual lens to understand the experiences, thoughts, and actions of a person posing a question, allowing the reader to offer a solution by understanding and interpreting the specific visual language of a deck.
Hinduism is one of the oldest religions in the world and one of the most practiced today. It is full of fantastical myths and heroic legends, as well as undercurrents of feminism contrasted with misogyny and patriarchy. Hindu myths are contradictory as stories have evolved over time and have been retold with millions of differing perspectives.
In my thesis, I portrayed the 22 archetypes of the Major Arcana of the tarot through the lens of Hindu mythology as well as the broader pan-Indian culture. I include ancient stories and references to modern social issues. I visually communicated the connections between characters of Hindu mythology and the archetypes of the tarot with 22 watercolor paintings. This project was an opportunity to explore both the tarot through Hinduism, vice-versa. It allowed for the development of a deeper connection with spirituality and religion, along with a greater understanding of visual communication.
Hinduism is one of the oldest religions in the world and one of the most practiced today. It is full of fantastical myths and heroic legends, as well as undercurrents of feminism contrasted with misogyny and patriarchy. Hindu myths are contradictory as stories have evolved over time and have been retold with millions of differing perspectives.
In my thesis, I portrayed the 22 archetypes of the Major Arcana of the tarot through the lens of Hindu mythology as well as the broader pan-Indian culture. I include ancient stories and references to modern social issues. I visually communicated the connections between characters of Hindu mythology and the archetypes of the tarot with 22 watercolor paintings. This project was an opportunity to explore both the tarot through Hinduism, vice-versa. It allowed for the development of a deeper connection with spirituality and religion, along with a greater understanding of visual communication.
ContributorsHarve, Prathima (Author) / Jenik, Adriene (Thesis director) / Codell, Julie (Committee member) / Zirbel, Lisa (Committee member) / School of Molecular Sciences (Contributor) / School of Art (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
While specific resistance mechanisms to targeted inhibitors in BRAF-mutant cutaneous melanoma have been identified, surprisingly little is known about the rate at which resistance develops under different treatment options. There is increasing evidence that resistance arises from pre-existing clones rather than from de novo mutations, but there remains the need for a better understanding of how different drugs affect the fitness of clones within a tumor population and promote or delay the emergence of resistance. To this end, we have developed an assay that defines the in vitro rate of adaptation by analyzing the progressive change in sensitivity of a melanoma cell line to different treatments. We performed a proof-of-theory experiment based on the hypothesis that drugs that cause cell death (cytotoxic) impose a higher selection pressure for drug-resistant clones than drugs that cause cell-cycle arrest (cytostatic drugs), thereby resulting in a faster rate of adaptation. We tested this hypothesis by continuously treating the BRAFV600E melanoma cell line A375 with the cytotoxic MEK inhibitor E6201 and the cytostatic MEK inhibitor trametinib, both of which are known to be effective in the setting of constitutive oncogenic signaling driven by the BRAF mutation. While the identification of confounding factors prevented the direct comparison between E6201-treated and trametinib-treated cells, we observed that E6201-treated cells demonstrate decreased drug sensitivity compared to vehicle-treated cells as early as 18 days after treatment begins. We were able to quantify this rate of divergence at 2.6% per passage by measuring the increase over time in average viability difference between drug-treated and vehicle-treated cells within a DDR analysis. We argue that this value correlates to the rate of adaptation. Furthermore, this study includes efforts to establish a barcoded cell line to allow for individual clonal tracking and efforts to identify synergistic and antagonist drug combinations for use in future experiments. Ultimately, we describe here a novel system capable of quantifying adaptation rate in cancer cells undergoing treatment, and we anticipate that this assay will prove helpful in identifying treatment options that circumvent or delay resistance through future hypothesis-driven experiments.
ContributorsDe Luca, Valerie Jean (Author) / Wilson Sayres, Melissa (Thesis director) / Trent, Jeff (Committee member) / Hendricks, William (Committee member) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12