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There is increasing interest in the medical and behavioral health communities towards developing effective strategies for the treatment of chronic diseases. Among these lie adaptive interventions, which consider adjusting treatment dosages over time based on participant response. Control engineering offers a broad-based solution framework for optimizing the effectiveness of such

There is increasing interest in the medical and behavioral health communities towards developing effective strategies for the treatment of chronic diseases. Among these lie adaptive interventions, which consider adjusting treatment dosages over time based on participant response. Control engineering offers a broad-based solution framework for optimizing the effectiveness of such interventions. In this thesis, an approach is proposed to develop dynamical models and subsequently, hybrid model predictive control schemes for assigning optimal dosages of naltrexone, an opioid antagonist, as treatment for a chronic pain condition known as fibromyalgia. System identification techniques are employed to model the dynamics from the daily diary reports completed by participants of a blind naltrexone intervention trial. These self-reports include assessments of outcomes of interest (e.g., general pain symptoms, sleep quality) and additional external variables (disturbances) that affect these outcomes (e.g., stress, anxiety, and mood). Using prediction-error methods, a multi-input model describing the effect of drug, placebo and other disturbances on outcomes of interest is developed. This discrete time model is approximated by a continuous second order model with zero, which was found to be adequate to capture the dynamics of this intervention. Data from 40 participants in two clinical trials were analyzed and participants were classified as responders and non-responders based on the models obtained from system identification. The dynamical models can be used by a model predictive controller for automated dosage selection of naltrexone using feedback/feedforward control actions in the presence of external disturbances. The clinical requirement for categorical (i.e., discrete-valued) drug dosage levels creates a need for hybrid model predictive control (HMPC). The controller features a multiple degree-of-freedom formulation that enables the user to adjust the speed of setpoint tracking, measured disturbance rejection and unmeasured disturbance rejection independently in the closed loop system. The nominal and robust performance of the proposed control scheme is examined via simulation using system identification models from a representative participant in the naltrexone intervention trial. The controller evaluation described in this thesis gives credibility to the promise and applicability of control engineering principles for optimizing adaptive interventions.
ContributorsDeśapāṇḍe, Sunīla (Author) / Rivera, Daniel E. (Thesis advisor) / Si, Jennie (Committee member) / Tsakalis, Konstantinos (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Proportional-Integral-Derivative (PID) controllers are a versatile category of controllers that are commonly used in the industry as control systems due to the ease of their implementation and low cost. One problem that continues to intrigue control designers is the matter of finding a good combination of the three parameters -

Proportional-Integral-Derivative (PID) controllers are a versatile category of controllers that are commonly used in the industry as control systems due to the ease of their implementation and low cost. One problem that continues to intrigue control designers is the matter of finding a good combination of the three parameters - P, I and D of these controllers so that system stability and optimum performance is achieved. Also, a certain amount of robustness to the process is expected from the PID controllers. In the past, many different methods for tuning PID parameters have been developed. Some notable techniques are the Ziegler-Nichols, Cohen-Coon, Astrom methods etc. For all these techniques, a simple limitation remained with the fact that for a particular system, there can be only one set of tuned parameters; i.e. there are no degrees of freedom involved to readjust the parameters for a given system to achieve, for instance, higher bandwidth. Another limitation in most cases is where a controller is designed in continuous time then converted into discrete-time for computer implementation. The drawback of this method is that some robustness due to phase and gain margin is lost in the process. In this work a method of tuning PID controllers using a loop-shaping approach has been developed where the bandwidth of the system can be chosen within an acceptable range. The loop-shaping is done against a Glover-McFarlane type ℋ∞ controller which is widely accepted as a robust control design method. The numerical computations are carried out entirely in discrete-time so there is no loss of robustness due to conversion and approximations near Nyquist frequencies. Some extra degrees of freedom owing to choice of bandwidth and capability of choosing loop-shapes are also involved and are discussed in detail. Finally, comparisons of this method against existing techniques for tuning PID controllers both in continuous and in discrete-time are shown. The results tell us that our design performs well for loop-shapes that are achievable through a PID controller.
ContributorsShafique, Md. Ashfaque Bin (Author) / Tsakalis, Konstantinos S. (Thesis advisor) / Rodriguez, Armando A. (Committee member) / Si, Jennie (Committee member) / Arizona State University (Publisher)
Created2011
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Description
This thesis discusses control and obstacle avoidance for non-holonomic differential drive mobile vehicles. The two important behaviors for the vehicle can be defined as go to goal and obstacle avoidance behavior. This thesis discusses both behaviors in detail. Go to goal behavior is the ability of the mobile vehicle to

This thesis discusses control and obstacle avoidance for non-holonomic differential drive mobile vehicles. The two important behaviors for the vehicle can be defined as go to goal and obstacle avoidance behavior. This thesis discusses both behaviors in detail. Go to goal behavior is the ability of the mobile vehicle to go from one particular co-ordinate to another. Cruise control, cartesian and posture stabilization problems are discussed as the part of this behavior. Control strategies used for the above three problems are explained in the thesis. Matlab simulations are presented to verify these controllers. Obstacle avoidance behavior ensures that the vehicle doesn't hit object in its path while going towards the goal. Three different techniques for obstacle avoidance which are useful for different kind of obstacles are described in the thesis. Matlab simulations are presented to show and discuss the three techniques. The controls discussed for the cartesian and posture stabilization were implemented on a low cost miniature vehicle to verify the results practically. The vehicle is described in the thesis in detail. The practical results are compared with the simulations. Hardware and matlab codes have been provided as a reference for the reader.
ContributorsChopra, Dhruv (Author) / Rodriguez, Armando A (Thesis advisor) / Tsakalis, Konstantinos (Committee member) / Si, Jennie (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The problem of systematically designing a control system continues to remain a subject of intense research. In this thesis, a very powerful control system design environment for Linear Time-Invariant (LTI) Multiple-Input Multiple-Output (MIMO) plants is presented. The environment has been designed to address a broad set of closed loop metrics

The problem of systematically designing a control system continues to remain a subject of intense research. In this thesis, a very powerful control system design environment for Linear Time-Invariant (LTI) Multiple-Input Multiple-Output (MIMO) plants is presented. The environment has been designed to address a broad set of closed loop metrics and constraints; e.g. weighted H-infinity closed loop performance subject to closed loop frequency and/or time domain constraints (e.g. peak frequency response, peak overshoot, peak controls, etc.). The general problem considered - a generalized weighted mixed-sensitivity problem subject to constraints - permits designers to directly address and tradeoff multivariable properties at distinct loop breaking points; e.g. at plant outputs and at plant inputs. As such, the environment is particularly powerful for (poorly conditioned) multivariable plants. The Youla parameterization is used to parameterize the set of all stabilizing LTI proper controllers. This is used to convexify the general problem being addressed. Several bases are used to turn the resulting infinite-dimensional problem into a finite-dimensional problem for which there exist many efficient convex optimization algorithms. A simple cutting plane algorithm is used within the environment. Academic and physical examples are presented to illustrate the utility of the environment.
ContributorsPuttannaiah, Karan (Author) / Rodriguez, Armando A (Thesis advisor) / Tsakalis, Konstantinos S (Committee member) / Si, Jennie (Committee member) / Arizona State University (Publisher)
Created2013
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Description
A systematic top down approach to minimize risk and maximize the profits of an investment over a given period of time is proposed. Macroeconomic factors such as Gross Domestic Product (GDP), Consumer Price Index (CPI), Outstanding Consumer Credit, Industrial Production Index, Money Supply (MS), Unemployment Rate, and Ten-Year Treasury are

A systematic top down approach to minimize risk and maximize the profits of an investment over a given period of time is proposed. Macroeconomic factors such as Gross Domestic Product (GDP), Consumer Price Index (CPI), Outstanding Consumer Credit, Industrial Production Index, Money Supply (MS), Unemployment Rate, and Ten-Year Treasury are used to predict/estimate asset (sector ETF`s) returns. Fundamental ratios of individual stocks are used to predict the stock returns. An a priori known cash-flow sequence is assumed available for investment. Given the importance of sector performance on stock performance, sector based Exchange Traded Funds (ETFs) for the S&P; and Dow Jones are considered and wealth is allocated. Mean variance optimization with risk and return constraints are used to distribute the wealth in individual sectors among the selected stocks. The results presented should be viewed as providing an outer control/decision loop generating sector target allocations that will ultimately drive an inner control/decision loop focusing on stock selection. Receding horizon control (RHC) ideas are exploited to pose and solve two relevant constrained optimization problems. First, the classic problem of wealth maximization subject to risk constraints (as measured by a metric on the covariance matrices) is considered. Special consideration is given to an optimization problem that attempts to minimize the peak risk over the prediction horizon, while trying to track a wealth objective. It is concluded that this approach may be particularly beneficial during downturns - appreciably limiting downside during downturns while providing most of the upside during upturns. Investment in stocks during upturns and in sector ETF`s during downturns is profitable.
ContributorsChitturi, Divakar (Author) / Rodriguez, Armando (Thesis advisor) / Tsakalis, Konstantinos S (Committee member) / Si, Jennie (Committee member) / Arizona State University (Publisher)
Created2010
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Description
Object sorting is a very common application especially in the industry setting, but this is a labor intensive and time consuming process and it proves to be challenging if done manually. Thanks to the rapid development in technology now almost all these object sorting tasks are partially or completely automated.

Object sorting is a very common application especially in the industry setting, but this is a labor intensive and time consuming process and it proves to be challenging if done manually. Thanks to the rapid development in technology now almost all these object sorting tasks are partially or completely automated. Image processing techniques are essential for the full operation of such a pick and place robot as it is responsible for perceiving the environment and to correctly identify ,classify and localize the different objects in it. In order for the robots to perform accurate object sorting with efficiency and stability this thesis discusses how different Deep learning based perception techniques can be used. In the era of Artificial Intelligence this sorting problem can be done more efficiently than the existing techniques. This thesis presents different image processing techniques and algorithms that can be used to perform object sorting efficiently. A comparison between three different deep learning based techniques is presented and their pros and cons are discussed. Furthermore this thesis also presents a comprehensive study about the kinematics and the dynamics involved in a 2 Degree of Freedom Robotic Manipulator .
ContributorsRanganathan, Pavithra (Author) / Rodriguez, Armando (Thesis advisor) / Si, Jennie (Committee member) / Berman, Spring (Committee member) / Arizona State University (Publisher)
Created2021
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Description
This dissertation is focused on developing an algorithm to provide current state estimation and future state predictions for biomechanical human walking features. The goal is to develop a system which is capable of evaluating the current action a subject is taking while walking and then use this to predict the

This dissertation is focused on developing an algorithm to provide current state estimation and future state predictions for biomechanical human walking features. The goal is to develop a system which is capable of evaluating the current action a subject is taking while walking and then use this to predict the future states of biomechanical features.

This work focuses on the exploration and analysis of Interaction Primitives (Amor er al, 2014) and their relevance to biomechanical prediction for human walking. Built on the framework of Probabilistic Movement Primitives, Interaction Primitives utilize an EKF SLAM algorithm to localize and map a distribution over the weights of a set of basis functions. The prediction properties of Bayesian Interaction Primitives were utilized to predict real-time foot forces from a 9 degrees of freedom IMUs mounted to a subjects tibias. This method shows that real-time human biomechanical features can be predicted and have a promising link to real-time controls applications.
ContributorsClark, Geoffrey Mitchell (Author) / Ben Amor, Heni (Thesis advisor) / Si, Jennie (Committee member) / Berisha, Visar (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Unmanned aerial vehicles (UAVs) are widely used in many applications because of their small size, great mobility and hover performance. This has been a consequence of the fast development of electronics, cheap lightweight flight controllers for accurate positioning and cameras. This thesis describes modeling, control and design of an oblique-cross-quadcopter

Unmanned aerial vehicles (UAVs) are widely used in many applications because of their small size, great mobility and hover performance. This has been a consequence of the fast development of electronics, cheap lightweight flight controllers for accurate positioning and cameras. This thesis describes modeling, control and design of an oblique-cross-quadcopter platform for indoor-environments.

One contribution of the work was the design of a new printed-circuit-board (PCB) flight controller (called MARK3). Key features/capabilities are as follows:

(1) a Teensy 3.2 microcontroller with 168MHz overclock –used for communications, full-state estimation and inner-outer loop hierarchical rate-angle-speed-position control,

(2) an on-board MEMS inertial-measurement-unit (IMU) which includes an LSM303D (3DOF-accelerometer and magnetometer), an L3GD20 (3DOF-gyroscope) and a BMP180 (barometer) for attitude estimation (barometer/magnetometer not used),

(3) 6 pulse-width-modulator (PWM) output pins supports up to 6 rotors

(4) 8 PWM input pins support up to 8-channel 2.4 GHz transmitter/receiver for manual control,

(5) 2 5V servo extension outputs for other requirements (e.g. gimbals),

(6) 2 universal-asynchronous-receiver-transmitter (UART) serial ports - used by flight controller to process data from Xbee; can be used for accepting outer-loop position commands from NVIDIA TX2 (future work),

(7) 1 I2C-serial-protocol two-wire port for additional modules (used to read data from IMU at 400 Hz),

(8) a 20-pin port for Xbee telemetry module connection; permits Xbee transceiver on desktop PC to send position/attitude commands to Xbee transceiver on quadcopter.

The quadcopter platform consists of the new MARK3 PCB Flight Controller, an ATG-250 carbon-fiber frame (250 mm), a DJI Snail propulsion-system (brushless-three-phase-motor, electronic-speed-controller (ESC) and propeller), an HTC VIVE Tracker and RadioLink R9DS 9-Channel 2.4GHz Receiver. This platform is completely compatible with the HTC VIVE Tracking System (HVTS) which has 7ms latency, submillimeter accuracy and a much lower price compared to other millimeter-level tracking systems.

The thesis describes nonlinear and linear modeling of the quadcopter’s 6DOF rigid-body dynamics and brushless-motor-actuator dynamics. These are used for hierarchical-classical-control-law development near hover. The HVTS was used to demonstrate precision hover-control and path-following. Simulation and measured flight-data are shown to be similar. This work provides a foundation for future precision multi-quadcopter formation-flight-control.
ContributorsLu, Shi (Author) / Rodriguez, Armando A. (Thesis advisor) / Tsakalis, Konstantinos (Committee member) / Si, Jennie (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Toward the ambitious long-term goal of a fleet of cooperating Flexible Autonomous Machines operating in an uncertain Environment (FAME), this thesis addresses several

critical modeling, design and control objectives for ground vehicles. One central objective was to show how off-the-shelf (low-cost) remote-control (RC) “toy” vehicles can be converted into intelligent multi-capability

Toward the ambitious long-term goal of a fleet of cooperating Flexible Autonomous Machines operating in an uncertain Environment (FAME), this thesis addresses several

critical modeling, design and control objectives for ground vehicles. One central objective was to show how off-the-shelf (low-cost) remote-control (RC) “toy” vehicles can be converted into intelligent multi-capability robotic-platforms for conducting FAME research. This is shown for two vehicle classes: (1) six differential-drive (DD) RC vehicles called Thunder Tumbler (DDTT) and (2) one rear-wheel drive (RWD) RC car called Ford F-150 (1:14 scale). Each DDTT-vehicle was augmented to provide a substantive suite of capabilities as summarized below (It should be noted, however, that only one DDTT-vehicle was augmented with an inertial measurement unit (IMU) and 2.4 GHz RC capability): (1) magnetic wheel-encoders/IMU for(dead-reckoning-based) inner-loop speed-control and outer-loop position-directional-control, (2) Arduino Uno microcontroller-board for encoder-based inner-loop speed-control and encoder-IMU-ultrasound-based outer-loop cruise-position-directional-separation-control, (3) Arduino motor-shield for inner-loop motor-speed-control, (4)Raspberry Pi II computer-board for demanding outer-loop vision-based cruise- position-directional-control, (5) Raspberry Pi 5MP camera for outer-loop cruise-position-directional-control (exploiting WiFi to send video back to laptop), (6) forward-pointing ultrasonic distance/rangefinder sensor for outer-loop separation-control, and (7) 2.4 GHz spread-spectrum RC capability to replace original 27/49 MHz RC. Each “enhanced”/ augmented DDTT-vehicle costs less than 􀀀175 but offers the capability of commercially available vehicles costing over 􀀀500. Both the Arduino and Raspberry are low-cost, well-supported (software wise) and easy-to-use. For the vehicle classes considered (i.e. DD, RWD), both kinematic and dynamical (planar xy) models are examined. Suitable nonlinear/linear-models are used to develop inner/outer-loopcontrol laws.

All demonstrations presented involve enhanced DDTT-vehicles; one the F-150; one a quadrotor. The following summarizes key hardware demonstrations: (1) cruise-control along line, (2) position-control along line (3) position-control along curve (4) planar (xy) Cartesian stabilization, (5) cruise-control along jagged line/curve, (6) vehicle-target spacing-control, (7) multi-robot spacing-control along line/curve, (8) tracking slowly-moving remote-controlled quadrotor, (9) avoiding obstacle while moving toward target, (10) RC F-150 followed by DDTT-vehicle. Hardware data/video is compared with, and corroborated by, model-based simulations. In short, many capabilities that are critical for reaching the longer-term FAME goal are demonstrated.
ContributorsLin, Zhenyu (Author) / Rodriguez, Armando Antonio (Committee member) / Si, Jennie (Committee member) / Berman, Spring Melody (Committee member) / Arizona State University (Publisher)
Created2015
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Description
To uncover the neural correlates to go-directed behavior, single unit action potentials are considered fundamental computing units and have been examined by different analytical methodologies under a broad set of hypotheses. Using a behaving rat performing a directional choice learning task, we aim to study changes in rat's cortical neural

To uncover the neural correlates to go-directed behavior, single unit action potentials are considered fundamental computing units and have been examined by different analytical methodologies under a broad set of hypotheses. Using a behaving rat performing a directional choice learning task, we aim to study changes in rat's cortical neural patterns while he improved his task performance accuracy from chance to 80% or higher. Specifically, simultaneous multi-channel single unit neural recordings from the rat's agranular medial (AGm) and Agranular lateral (AGl) cortices were analyzed using joint peristimulus time histogram (JPSTHs), which effectively unveils firing coincidences in neural action potentials. My results based on data from six rats revealed that coincidences of pair-wise neural action potentials are higher when rats were performing the task than they were not at the learning stage, and this trend abated after the rats learned the task. Another finding is that the coincidences at the learning stage are stronger than that when the rats learned the task especially when they were performing the task. Therefore, this coincidence measure is the highest when the rats were performing the task at the learning stage. This may suggest that neural coincidences play a role in the coordination and communication among populations of neurons engaged in a purposeful act. Additionally, attention and working memory may have contributed to the modulation of neural coincidences during the designed task.
ContributorsCheng, Bing (Author) / Si, Jennie (Thesis advisor) / Chae, Junseok (Committee member) / Seo, Jae-Sun (Committee member) / Arizona State University (Publisher)
Created2014