Matching Items (4)
Filtering by
- All Subjects: bicultural stress
- Creators: Corbin, William
Description
Hispanic/Latinx college students are at a greater risk for developing problematic alcohol use and negative mental health outcomes such as depression and anxiety because they experience contextual stressors (i.e., financial stress, academic stress, peer pressure) and cultural stressors (i.e., bicultural stress, acculturative stress, discrimination). Bicultural stress may be a risk factor for depressive, anxiety, and alcohol use disorder (AUD) symptoms. The cultural value of familism may play a protective role in Hispanic/Latinx college students. The purpose of this study was to investigate the effects of bicultural stress on depressive, anxiety, and AUD symptoms in first-year Hispanic/Latinx college students, and the role familism plays on moderating the relationship between bicultural stress and the outcomes. The sample was taken from the Pathways to College Health Study (N = 264; Female = 74.9%), which was survey administered via Qualtrics to first-year, Hispanic/Latinx college students at Arizona State University. The survey captured the participants’ levels of bicultural stress, familism, depressive, anxiety, and AUD symptoms. IBM SPSS Statistics was used for data analyses where three hierarchical regression models were run investigating the main effects and interaction effect of bicultural stress and familism. Results showed that higher levels of bicultural stress were associated with higher levels of mental health but were not associated with higher levels of AUD symptoms. Additionally, familism was not significantly associated with mental health or AUD symptoms suggesting familism may not play a substantial role in Hispanic/Latinx college students. There was no interaction found between familism and bicultural stress on the outcomes. These findings may aide in informing Hispanic/Latinx college students, universities, and clinicians on the impact bicultural stress may have on mental health outcomes.
ContributorsGhazoul, Marilyn (Author) / Su, Jinni (Thesis director) / Corbin, William (Committee member) / Cruz, Rick (Committee member) / Barrett, The Honors College (Contributor) / School of Art (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2023-12
ContributorsGhazoul, Marilyn (Author) / Su, Jinni (Thesis director) / Corbin, William (Committee member) / Cruz, Rick (Committee member) / Barrett, The Honors College (Contributor) / School of Art (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2023-12
ContributorsGhazoul, Marilyn (Author) / Su, Jinni (Thesis director) / Corbin, William (Committee member) / Cruz, Rick (Committee member) / Barrett, The Honors College (Contributor) / School of Art (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2023-12
Description
Major Depressive Disorder (MDD) affects over 300 million people worldwide, with the hippocampus showing decreased volume and activity in patients with MDD. The current study investigated whether a novel preclinical model of depression, unpredictable intermittent restraint (UIR), would decrease hippocampal neuronal dendritic complexity. Adult Sprague Dawley rats (24 male, 24 female) were equally divided into 4 groups: control males (CON-M), UIR males (UIR-M), control females (CON-F) and UIR females (UIR-F). UIR groups received restraint and shaking on an orbital shaker on a randomized schedule for 30 or 60 minutes/day for two to six days in a row for 26 days (21 total UIR days) before behavioral testing commenced. UIR continued and was interspersed between behavioral test days. At the end of behavioral testing, brains were processed. The behavior is published and not part of my honor’s thesis; my contribution involved quantifying and analyzing neurons in the hippocampus. Several neuronal types are found in the CA3 subregion of the hippocampus and I focused on short shaft (SS) neurons, which show different sensitivities to stress than the more common long shaft (LS) variety. Brains sections were mounted to slides and Golgi stained. SS neurons were drawn using a microscope with camera lucida attachment and quantified using the number of bifurcations and dendritic intersections as metrics for dendritic complexity in the apical and basal areas separately. The hypothesis that SS neurons in the CA3 region of the hippocampus would exhibit apical dendritic simplification in both sexes after UIR was not supported by our findings. In contrast, following UIR, SS apical dendrites were more complex in both sexes compared to controls. Although unexpected, we believe that the UIR paradigm was an effective stressor, robust enough to illicit neuronal adaptations. It appears that the time from the end of UIR to when the brain tissue was collected, or the post-stress recovery period, and/or repeated behavioral testing may have played a role in the observed increased neuronal complexity. Future studies are needed to parse out these potential effects.
ContributorsAcuna, Amanda Marie (Author) / Conrad, Cheryl (Thesis director) / Corbin, William (Committee member) / Olive, M. Foster (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12