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- All Subjects: Health
- Creators: Harrington Bioengineering Program
- Creators: School of International Letters and Cultures
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Description
Because children do not have the same decision-making powers as adults in matters affecting their health, their opinions have often been underrepresented in research (Bradding & Horstman, 1999). However, there is growing interest in the way that children view health because this knowledge elicits the development of more child-centered and effective approaches to health education and intervention (Bradding & Horstman, 1999). Professionals have often utilized the write-and-draw technique in school settings to gain a better understanding of how to best implement health education programs. The "bottom-up" approach of the write-and-draw method encourages participation and has been shown to elicit thoughtful responses about how children conceptualize health (Pridmore & Bendelow, 1995). This study uses the write-and-draw method to perform a cross- cultural comparison of child perspectives of health in the United States and Guatemala, countries that represent contrasting paradigms for child health. The results of this study are consistent with previous research, especially the emergent health themes. Children from the United States and Guatemala predominantly depicted health in terms of food. Guatemalan students were more likely to refer to hygienic practices and environmental conditions, while US children mentioned vegetables, water, and exercise as being healthy. For the unhealthy category, themes of poor hygiene, chips, fat/grease, fruit, carbohydrates, and environment were mentioned more often in Guatemala, while U.S. students listed sweets and fast food more frequently. Results support claims made in other literature that children's concepts of health are shaped by life experience and social context. Potential applications of the research include exposing areas (themes) where children are less likely to understand health implications and developing educational curriculum to increase a more comprehensive understanding of health.
ContributorsRenslow, Jillian Marie (Author) / Maupin, Jonathan (Thesis director) / BurnSilver, Shauna (Committee member) / Barrett, The Honors College (Contributor) / School of Human Evolution and Social Change (Contributor) / School of International Letters and Cultures (Contributor)
Created2015-05
Description
Short-term medical volunteer work via a nongovernmental organization is a popular tool for students in the health care field to gain experience, while further providing communities that normally lack health care options the opportunity to receive free care. One such organization, VIDA Volunteer Travel, has been successful in implementing this model in Central America. However, organizations of this form have not been evaluated for effectiveness or improvement. This exploratory study examines the effectiveness of VIDA based on six qualifying characteristics that make up a successful NGO. The researcher conducted in-depth, semi-structured interviews with 21 individuals, including VIDA staff members in Costa Rica and Nicaragua, health professionals working for VIDA, local community leaders, and volunteers participating in VIDA's programs. Summaries and quotes of these interviews were uploaded and analysed using Atlas.ti to identify common words and themes from the interviews. Informants frequently identified the organization as sustainable, both from a fiscal and ecological standpoint. The organization also successfully managed volunteers, although post-trip follow-up was lacking. Adherence to the mission statement and distribution of supplies allowed for improved organization and successful structure of the organization. Education and health promotion was also emphasized, although implementation of this education into the communities was lacking. Collaboration with the community and volunteers allowed for stringent, successful treatment to be given to patients, and ethical guidelines set up by the organization allowed for self-governance and improvement of the NGO. This study suggests future research opportunities for the organization, to evaluate its own impact and opportunities for improvement. Furthermore, suggestions are addressed that allow the organization to improve upon its well-implemented infrastructure, and allow for future organizations to use VIDA as a model for improvement.
ContributorsPearson, Presley Kyle (Author) / Yoshioka, Carlton (Thesis director) / Wang, Lili (Committee member) / Larsen, Dale (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor)
Created2013-05
Description
This report provides information concerning qualities of methylcellulose and how those properties affect further experimentation within the biomedical world. Utilizing the compound’s biocompatibility many issues, ranging from surgical to cosmetic, can be solved. As of recent, studies indicate, methylcellulose has been used as a physically cross-linked gel, which cannot sustain a solid form within the body. Therefore, this report will ultimately explore the means of creating a non-degradable, injectable, chemically cross-linking methylcellulose- based hydrogel. Methylcellulose will be evaluated and altered in experiments conducted within this report and a chemical cross-linker, developed from Jeffamine ED 2003 (O,O′-Bis(2-aminopropyl) polypropylene glycol-block-polyethylene glycol-block-polypropylene glycol), will be created. Experimentation with these elements is outlined here, and will ultimately prompt future revisions and analysis.
ContributorsBundalo, Zoran Luka (Author) / Vernon, Brent (Thesis director) / LaBelle, Jeffrey (Committee member) / Overstreet, Derek (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2013-05
Description
This project aims to address the current protocol regarding the diagnosis and treatment of traumatic brain injury (TBI) in medical industries around the world. Although there are various methods used to qualitatively determine if TBI has occurred to a patient, this study attempts to aid in the creation of a system for quantitative measurement of TBI and its relative magnitude. Through a method of artificial evolution/selection called phage display, an antibody that binds highly specifically to a post-TBI upregulated brain chondroitin sulfate proteoglycan called neurocan has been identified. As TG1 Escheria Coli bacteria were infected with KM13 helper phage and M13 filamentous phage in conjunction, monovalent display of antibody fragments (ScFv) was performed. The ScFv bind directly to the neurocan and from screening, phage that produced ScFv's with higher affinity and specificity to neurocan were separated and purified. Future research aims to improve the ScFv characteristics through increased screening toward neurocan. The identification of a highly specific antibody could lead to improved targeting of neurocan post-TBI in-vivo, aiding researchers in quantitatively defining TBI by visualizing its magnitude.
ContributorsSeelig, Timothy Scott (Author) / Stabenfeldt, Sarah (Thesis director) / Ankeny, Casey (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2015-05
Description
Attending a university is a stressful transition for many students leaving their respective support systems. Many universities attempt to mitigate this stress by offering numerous campus resources such as, tutoring services, counseling services, and health services. However, research has shown that many of these resources are under utilized by the general student population because of barriers that include student perception, awareness, and access. Being able to understand these barriers that lead to the under utilization of campus resources can assist with creating resources that are more visible, engaging, and attractive to student populations on many campuses. The question being asked is: how to create an engaging health resource that is attractive, visible, and accessible to students?
Based on research analyzed on the barriers between students and campus resources, the optimization of student outreach, and marketing strategies directed towards students, the creation of a student-led campus health resource followed. Analysis of this research showcased that the medium in which students resources were promoted, and the framework of the resource have an impact on students' awareness of the resource, attractiveness of the student resource, and student resource engagement. Based on these analyses and results, the creation of HealthU occurred to provide a visible, engaging, and attractive student resource to the Arizona State University student body.
Based on research analyzed on the barriers between students and campus resources, the optimization of student outreach, and marketing strategies directed towards students, the creation of a student-led campus health resource followed. Analysis of this research showcased that the medium in which students resources were promoted, and the framework of the resource have an impact on students' awareness of the resource, attractiveness of the student resource, and student resource engagement. Based on these analyses and results, the creation of HealthU occurred to provide a visible, engaging, and attractive student resource to the Arizona State University student body.
ContributorsAlcazar, Ivan (Co-author) / Mora, Leslie (Co-author) / Freeman, Javon (Co-author) / Byrne, Jared (Thesis director) / Sebold, Brent (Committee member) / Department of Information Systems (Contributor) / School of Politics and Global Studies (Contributor) / Dean, W.P. Carey School of Business (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The dilemma of the lack of prenatal and neonatal healthcare has been prevalent among third world countries for many years. The lack of prenatal healthcare has been shown to have direct links to spontaneous preterm births from which low-birth weight in babies can be a result. The World Health Organization has identified preterm birth as one of the biggest overseen burdens in developing countries.
This study seeks to answer the research questions: What are the major risk factors associated with the lack of prenatal and neonatal healthcare in developing countries? What are potential routes of intervention (ROI) to help these countries? The goal is to analyze the risk factors and determine if there are any ROIs available to minimize potential incidents or accidents associated with complications of preterm birth.
A few potential risk factors include: poverty, a mother’s lack of education, a lack of professional visitation during pregnancy, having a short cervix, and routine use of Ultrasound. This research paper has identified that keeping ultrasound diagnostics to a minimum, seeking professional help during pregnancy, incorporating corticosteroids for preterm births, implementing Kangaroo Mother Care, and Cervical Cerclage are interventions that can reduce preterm births and the associated complications that come with it. We believe that further research, regarding compliance of each of these interventions, would show reduction of preterm births and low birth weight in developing countries.
This study seeks to answer the research questions: What are the major risk factors associated with the lack of prenatal and neonatal healthcare in developing countries? What are potential routes of intervention (ROI) to help these countries? The goal is to analyze the risk factors and determine if there are any ROIs available to minimize potential incidents or accidents associated with complications of preterm birth.
A few potential risk factors include: poverty, a mother’s lack of education, a lack of professional visitation during pregnancy, having a short cervix, and routine use of Ultrasound. This research paper has identified that keeping ultrasound diagnostics to a minimum, seeking professional help during pregnancy, incorporating corticosteroids for preterm births, implementing Kangaroo Mother Care, and Cervical Cerclage are interventions that can reduce preterm births and the associated complications that come with it. We believe that further research, regarding compliance of each of these interventions, would show reduction of preterm births and low birth weight in developing countries.
ContributorsHuapaya, Eduardo Luciano (Author) / Muthuswamy, Jitendran (Thesis director) / Comar, William (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The primary goal of this paper is to analyze a tool used for measuring human
development on a global scale. Originally, development within a country was solely judged by the degree of economic growth by way of Gross National Product (GNP) and per capita income. Holistically, GNP measures the total extent of economic activity of a country’s people within a given time period. (Rutherford, 2012). Critics found several issues with this one-dimensional approach of measuring human development. What failed to be recognized was the distribution of income among the country’s citizens. Higher incomes often favor men within the majority when compared to women and people of minority groups (Feiner & Roberts, 1990). GNP also failed to recognize the social limitations under a government. In other words, are there limitations as to what goods can be bought and who can buy them?
development on a global scale. Originally, development within a country was solely judged by the degree of economic growth by way of Gross National Product (GNP) and per capita income. Holistically, GNP measures the total extent of economic activity of a country’s people within a given time period. (Rutherford, 2012). Critics found several issues with this one-dimensional approach of measuring human development. What failed to be recognized was the distribution of income among the country’s citizens. Higher incomes often favor men within the majority when compared to women and people of minority groups (Feiner & Roberts, 1990). GNP also failed to recognize the social limitations under a government. In other words, are there limitations as to what goods can be bought and who can buy them?
ContributorsSteeley, Emily Anne (Author) / Parmentier, Mary Jane (Thesis director) / Grgich, Traci (Committee member) / Harrington Bioengineering Program (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The aim of the present study was to review the symptoms and current treatment options of the most common skin infections seen in outpatient settings and develop a preliminary alternative treatment solution. The specific skin infections evaluated were those caused by Staphylococcus and Streptococcus bacterial species, and are frequently treated with a wide variety of systemic antibiotics or topical ointments. Systemic antibiotics have shown increased occurrence of adverse side effects as well as the development of antibiotic-resistant bacteria. Additionally, these medications are usually overprescribed, which may further exacerbate negative side effects. Another issue that is addressed is the development of infections following treatment of a new laceration or other trauma to the skin. A patient may be treated for their wound with stitches or another alternative, but there is still the possibility of developing an infection later.
This study synthesizes information found from extensive research and provides a review of the most optimal techniques for developing an alternative to systemic antibiotics. The final deliverable is a report detailing the significant findings and discussing the ways that this solution may be developed further and implemented in a clinical setting. The solution is a hydrogel bandage designed to deliver antibiotics directly to the wound site, while also offering protection and enhanced wound healing. The target population is patients suffering from skin conditions in an outpatient setting. The antibiotics of interest for this solution are clindamycin, doxycycline, and trimethoprim-sulfamethoxazole (co-trimoxazole), as they offer excellent treatment against gram-positive bacteria and methicillin-resistant Staphylococcus aureus. However, other broad-spectrum antibiotics could potentially be incorporated to protect against gram-negative bacteria. The design features a polyvinyl alcohol (PVA) hydrogel that has shown many properties that are beneficial to biomedical applications, including biocompatibility, flexibility, high drug-loading capacity, high absorption of wound exudate, increased promotion of wound healing, and more. Preliminary mathematical models of the hydrogel’s drug delivery behaviors are also included. Due to the scope and timeframe of this project, the majority of findings herein are based on research of prior literature instead of development of the novel device. Future directions would include further research and development of the mechanisms behind the device, creation of a physical prototype, experimental testing, and statistical analyses to verify device specifications and capabilities.
This study synthesizes information found from extensive research and provides a review of the most optimal techniques for developing an alternative to systemic antibiotics. The final deliverable is a report detailing the significant findings and discussing the ways that this solution may be developed further and implemented in a clinical setting. The solution is a hydrogel bandage designed to deliver antibiotics directly to the wound site, while also offering protection and enhanced wound healing. The target population is patients suffering from skin conditions in an outpatient setting. The antibiotics of interest for this solution are clindamycin, doxycycline, and trimethoprim-sulfamethoxazole (co-trimoxazole), as they offer excellent treatment against gram-positive bacteria and methicillin-resistant Staphylococcus aureus. However, other broad-spectrum antibiotics could potentially be incorporated to protect against gram-negative bacteria. The design features a polyvinyl alcohol (PVA) hydrogel that has shown many properties that are beneficial to biomedical applications, including biocompatibility, flexibility, high drug-loading capacity, high absorption of wound exudate, increased promotion of wound healing, and more. Preliminary mathematical models of the hydrogel’s drug delivery behaviors are also included. Due to the scope and timeframe of this project, the majority of findings herein are based on research of prior literature instead of development of the novel device. Future directions would include further research and development of the mechanisms behind the device, creation of a physical prototype, experimental testing, and statistical analyses to verify device specifications and capabilities.
ContributorsTanner, Emily Christine (Author) / Pizziconi, Vincent (Thesis director) / Nguyen, Eric (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The global population over the age of 60 is estimated to rise to 23% by 2050 only increase the prevalence of functional neurological disorders and stroke. Increase in cases of functional neurological disorders and strokes will place a greater burden on the healthcare industry, specifically physical therapy. Physical therapy is vital for a patient’s recovery of motor function which is time demanding and taxing on the physical therapist. Wearable robotics have been proven to improve functional outcomes in gait rehabilitation by providing controlled high dosage and high-intensity training. Accurate control strategies for assistive robotic exoskeletons are vital for repetitive high precisions assistance for cerebral plasticity to occur.
This thesis presents a preliminary determination and design of a control algorithm for an assistive ankle device developed by the ASU RISE Laboratory. The assistive ankle device functions by compressing a spring upon heel strike during gait, remaining compressed during mid-stance and then releasing upon initiation of heel-off. The relationship between surface electromyography and ground reactions forces were used for identification of user-initiated heel-off. The muscle activation of the tibialis anterior combined with the ground reaction forces of the heel pressure sensor generated potential features that will be utilized in the revised control algorithm for the assistive ankle device. Work on this project must proceed in order to test and validate the revised control algorithm to determine its accuracy and precision.
This thesis presents a preliminary determination and design of a control algorithm for an assistive ankle device developed by the ASU RISE Laboratory. The assistive ankle device functions by compressing a spring upon heel strike during gait, remaining compressed during mid-stance and then releasing upon initiation of heel-off. The relationship between surface electromyography and ground reactions forces were used for identification of user-initiated heel-off. The muscle activation of the tibialis anterior combined with the ground reaction forces of the heel pressure sensor generated potential features that will be utilized in the revised control algorithm for the assistive ankle device. Work on this project must proceed in order to test and validate the revised control algorithm to determine its accuracy and precision.
ContributorsGaytan-Jenkins, Daniel Rinaldo (Author) / Zhang, Wenlong (Thesis director) / Tyler, Jamie (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Ecological modeling can be used to analyze health risk behaviors and their relationship to ecological factors, which is useful in determining how social environmental factors influence an individual’s decisions. Environmental interactions shape the way that humans behave throughout the day, either through observation, action, or consequences. Specifically, health risk behaviors can be analyzed in relation to ecological factors. Alcohol drinking among college students has been a long concern and there are many risks associated with these behaviors in this population. Consistent engagement in health risk behaviors as a college student, such as drinking and smoking, can pose a much larger issues later in life and can lead to many different health problems. A research study was conducted in the form of a 27 question survey to determine and evaluate the impact of ecological factors on drinking and smoking behaviors among Arizona State University students. Ecological factors such as demographics, living conditions, contexts of social interactions, and places where students spend most of their time were used to evaluate the relationship between drinking and smoking behaviors and the ecological factors, both on- and off- campus. The sample size of this study is 541 students. Statistical tests were conducted using Excel and RStudio to find relationships between patterns of health risk behaviors and various ecological factors. The data from the survey was analyzed to address three main questions. The first question analyzed drinking behaviors in relation to demographics, specifically gender and race. The second question assessed drinking behaviors with participation in Greek life and clubs on campus. The third question evaluated the relationship between health risk behaviors and students’ living conditions, such as living on or off campus. The results show that while gender does not have a statistically significant influence on drinking behaviors, race does. White individuals are more likely to engage in drinking behaviors and are more at risk than non-whites. Participation in Greek life was shown to be statistically significant in determining health risk behaviors, while involvement in clubs was not. Finally, on campus students are less likely to engage in health risk behaviors than off-campus students.
ContributorsWerbick, Meghan Lindsay (Co-author) / Andrade, Amber (Co-author) / Naik, Sparshee (Co-author) / Mubayi, Anuj (Thesis director) / Gaughan, Monica (Committee member) / School of Human Evolution & Social Change (Contributor, Contributor) / School of Politics and Global Studies (Contributor, Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05