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This paper takes a look at developing a technological start up revolving around the world of health and fitness. The entire process is documented, starting from the ideation phase, and continuing on to product testing and market research. The research done focuses on identifying a target market for a 24/7

This paper takes a look at developing a technological start up revolving around the world of health and fitness. The entire process is documented, starting from the ideation phase, and continuing on to product testing and market research. The research done focuses on identifying a target market for a 24/7 fitness service that connects clients with personal trainers. It is a good study on the steps needed in creating a business, and serves as a learning tool for how to bring a product to market.
ContributorsHeck, Kyle (Co-author) / Mitchell, Jake (Co-author) / Korczynski, Brian (Co-author) / Peck, Sidnee (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Finance (Contributor) / Department of Economics (Contributor) / Department of Management (Contributor) / Department of Psychology (Contributor) / Department of Supply Chain Management (Contributor) / School of Accountancy (Contributor) / W. P. Carey School of Business (Contributor)
Created2014-05
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Although discrimination is implicated in ethnic health disparities, social support may buffer against its negative effects on health. This study investigated whether prenatal maternal discrimination and social support would predict postpartum cortisol in low-income Hispanic women and infants. Among infants whose mothers reported high discrimination, low maternal social support was

Although discrimination is implicated in ethnic health disparities, social support may buffer against its negative effects on health. This study investigated whether prenatal maternal discrimination and social support would predict postpartum cortisol in low-income Hispanic women and infants. Among infants whose mothers reported high discrimination, low maternal social support was associated with high infant cortisol (ß= -0.293, p= 0.03). This provides evidence for the social buffering hypothesis.
ContributorsJewell, Shannon Linda (Author) / Luecken, Linda (Thesis director) / Presson, Clark (Committee member) / Gonzales, Nancy (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2013-05
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Description
Obesity has become a major area of research in many fields due to the increasing obesity rate not only in The United States, but also around the world. Research concerning obesity stigma has both physical and mental health implications. Weight bias and obesity stigma represent important research areas for health

Obesity has become a major area of research in many fields due to the increasing obesity rate not only in The United States, but also around the world. Research concerning obesity stigma has both physical and mental health implications. Weight bias and obesity stigma represent important research areas for health professionals as they confront these issues on a daily basis in interactions with their patients. To explore how gender, ethnicity, and a person's own BMI affect the stigma of certain weight related terms, a set of 264 participant's surveys on weight related situations on the campus of Arizona State University were analyzed. Using univariate analysis to determine frequency of words deemed most or least acceptable as well as independent t-test for gender and ANOVA for ethnicity and own BMI, we found that participant's view more clinical terms such as "unhealthy BMI" and "BMI" as acceptable words for use during a physician-patient interaction. Analysis across genders revealed the highest number of differences in terms, with females generally ranking terms across the board as less acceptable then men. Differences varied little between ethnicities; however, own BMI revealed more differences between terms; underweight participants did not rank any terms as positive. We analyzed average ATOP (Attitudes Toward Obese People) scores and found that there was no significant difference in average ATOP scores between gender and a participant's own BMI, but a statistical significance did exist between ethnic categories. This study showed that the term "obese/obesity", although normally considered to be a clinical term by many was not ranked as very positive across gender, ethnicity, or own BMI. Based on these findings, new material should be created to inform physicians on how to talk about weight related problems with certain populations of patients.
ContributorsBlasco, Drew Adair (Author) / Wutich, Amber (Thesis director) / Brewis Slade, Alexandra (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / Department of Psychology (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2014-12
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Description

Health and Wealthness is a podcast where your hosts, Emily Weigel and Hanaa Khan discuss pressing and trending topics about health and wealth that everyone should know about. Our first four episodes focus on the opioid crisis. Both the science and healthcare sides. We then go on to talk about

Health and Wealthness is a podcast where your hosts, Emily Weigel and Hanaa Khan discuss pressing and trending topics about health and wealth that everyone should know about. Our first four episodes focus on the opioid crisis. Both the science and healthcare sides. We then go on to talk about burnout and mental health in a conversational episode.

ContributorsKhan, Hanaa S (Co-author) / Weigel, Emily (Co-author) / Olive, Foster (Thesis director) / Bonfiglio, Thomas (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

This thesis project aims to help the AdviseAZ program reach out, guide, and prepare students for college by setting up a podcast to help answer questions and doubts high school students might have about college. A podcast like this would also help school counselors by relieving them of having to

This thesis project aims to help the AdviseAZ program reach out, guide, and prepare students for college by setting up a podcast to help answer questions and doubts high school students might have about college. A podcast like this would also help school counselors by relieving them of having to give out repetitive information about college, therefore opening time in their schedule to meet with students for in depth help. The podcast will provide episodes with information about college preparation and advice from college students and college representatives. The AdviseAZ podcast will help its partnered high school students between grades 9 through 12. The podcast will be new for AdviseAZ because as a program they have not explored this service idea for the students. It will be framed to be successful using the Bolman and Deal framework guidelines. These frames will allow the AdviseAZ podcast to prosper in a new way. Bolman and Deal's four-frame model has been a transforming business leadership. They use a multidisciplinary approach to management and provide tools for navigating the organization in a terrible circumstance. Organizations can see which of the four frames could draw to their needs for a solution or change.

ContributorsRodriguez, Noemi Araceli (Author) / deLusé, Stephanie (Thesis director) / Aleman, Shaylinn (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description
As of March 2020, there were over 112,400 patients actively waiting on the United States national organ transplant waitlist with only about 3,300 donors1. Although transplantation is an effective treatment for end-stage organ failure, the access to a procedure will vary depending on national regulations, cost of health care, extensive

As of March 2020, there were over 112,400 patients actively waiting on the United States national organ transplant waitlist with only about 3,300 donors1. Although transplantation is an effective treatment for end-stage organ failure, the access to a procedure will vary depending on national regulations, cost of health care, extensive screening processes, and the availability of organs2. Organ shortage is a worldwide problem, and the growing insufficiency has resulted patients becoming too for ill or dying while waiting3. Due to the varying wait times and costs of procedures, some patients have begun to outsource their own transplantation through international transactions, also known as transplant tourism2. The 2004 World Health Assembly resolution recognized these trades as a significant health policy issue, while also acknowledging the inability of national health care systems to meet the needs of patients4. To address this issue, a proposal will be made such that all live kidney and liver donors will be compensated $22,500 and $12,150 respectively through a cost-neutral scheme based on annual healthcare expenditures per organ that would be eliminated by a transplant. With this proposal, it is suggested that the organ transplant waitlist would not only be significantly reduced, but potentially eliminated, and the crisis of organ shortage would be defeated.
ContributorsMartin, Starla (Author) / Kingsbury, Jeffrey (Thesis director) / Edmonds, Hallie (Committee member) / School of Molecular Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The goal of this paper is to describe the current understanding of how a human’s remaining senses are affected by the onset of blindness through physiological adaptations. The main focuses of this paper stem around the brain and how it adapts to blindness through mechanisms such as neuroplasticity. This paper

The goal of this paper is to describe the current understanding of how a human’s remaining senses are affected by the onset of blindness through physiological adaptations. The main focuses of this paper stem around the brain and how it adapts to blindness through mechanisms such as neuroplasticity. This paper will explore the increased acuity of both tactile and auditory processing as well as spatial navigation resulting from the onset of blindness. This paper will also explore the enhanced ability of the blind to echolocate as well as the mechanisms of homeostasis that underlie this ability. Finally, this paper will report on the lack of enhancement for the senses of taste and smell in humans after the onset of blindness and possible reasons why there are no observed increases in potential. It is the hope of the writers that this paper will cover the current state of knowledge on the phenomenon of adaptations resulting from the onset of blindness to such an extent that this information can be presented in a podcast format later on.

Disclaimer: Due to the COVID-19 global pandemic, the final outcomes of this project were impacted and limited. Therefore, the rough draft practice podcast session has been uploaded to accompany the written thesis portion as final recordings could not be recorded at this time.
ContributorsMoyzes, Hannah (Co-author) / Fox, Dylan (Co-author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
The retinoid-X receptor (RXR) can form heterodimers with both the retinoic-acid
receptor (RAR) and vitamin D receptor (VDR). The RXR/RAR dimer is activated by ligand all
trans retinoic acid (ATRA), which culminates in gut-specific effector T cell migration. Similarly,
the VDR/RXR dimer binds 1,25(OH)2D3 to cause skin-specific effector T cell migration.

The retinoid-X receptor (RXR) can form heterodimers with both the retinoic-acid
receptor (RAR) and vitamin D receptor (VDR). The RXR/RAR dimer is activated by ligand all
trans retinoic acid (ATRA), which culminates in gut-specific effector T cell migration. Similarly,
the VDR/RXR dimer binds 1,25(OH)2D3 to cause skin-specific effector T cell migration.
Targeted migration is a potent addition to current vaccines, as it would induce activated T cell
trafficking to appropriate areas of the immune system and ensure optimal stimulation (40).
ATRA, while in use clinically, is limited by toxicity and chemical instability. Rexinoids
are stable, synthetically developed ligands specific for the RXR. We have previously shown that
select rexinoids can enhance upregulation of gut tropic CCR9 receptors on effector T cells.
However, it is important to establish whether these cells can actually migrate, to show the
potential of rexinoids as vaccine adjuvants that can cause gut specific T cell migration.
Additionally, since the RXR is a major contributor to VDR-mediated transcription and
epidermotropism (15), it is worth investigating whether these compounds can also function as
adjuvants that promote migration by increasing expression of skin tropic CCR10 receptors on T
cells.
Prior experiments have demonstrated that select rexinoids can induce gut tropic migration
of CD8+ T cells in an in vitro assay and are comparable in effectiveness to ATRA (7). The effect
of rexinoids on CD4+ T cells is unknown however, so the aim of this project was to determine if
rexinoids can cause gut tropic migration in CD4+ T cells to a similar extent. A secondary aim
was to investigate whether varying concentrations in 1,25-Dihydroxyvitamin D3 can be linked to
increasing CCR10 upregulation on Jurkat CD4+ T cells, with the future aim to combine 1,25
Dihydroxyvitamin D3 with rexinoids.
These hypotheses were tested using murine splenocytes for the migration experiment, and
human Jurkat CD4+ T cells for the vitamin D experiment. Migration was assessed using a
Transwell chemotaxis assay. Our findings support the potential of rexinoids as compounds
capable of causing gut-tropic migration in murine CD4+ T cells in vitro, like ATRA. We did not
observe conclusive evidence that vitamin D3 causes upregulated CCR10 expression, but this
experiment must be repeated with a human primary T cell line.
ContributorsDebray, Hannah Zara (Co-author) / Debray, Hannah (Co-author) / Blattman, Joseph (Thesis director) / Jurutka, Peter (Committee member) / Manhas, Kavita (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow it to go extended periods of time consuming little to

Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow it to go extended periods of time consuming little to no food. These adaptations also allow the body to recover quickly once food becomes available. They include changes in metabolism that allow different fuel sources to be used for energy, the storing of excess energy absorbed from food in the forms of glycogen and fat to be used in between meals, and a reduction in the basal metabolic rate in response to starvation, as well as physiological changes in the small intestines. Even in places where starvation is not a concern today, these adaptations are still important as they also have an effect on weight gain and dieting in addition to promoting survival when the body is in a starved state.

Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
ContributorsPhlipot, Stephanie Anne (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Homeless populations are often disproportionately impacted by several diseases due to factors such as overcrowding, unsanitary conditions, lack of access to healthcare and most importantly lack of education. The purpose of this project was to decrease a part of this health gap by spreading awareness of certain illnesses impacting Arizona’s

Homeless populations are often disproportionately impacted by several diseases due to factors such as overcrowding, unsanitary conditions, lack of access to healthcare and most importantly lack of education. The purpose of this project was to decrease a part of this health gap by spreading awareness of certain illnesses impacting Arizona’s homeless population and to increase the use plausible prevention methods. This was done through the creation of three simplified brochures that contained information regarding influenza, hepatitis, and schizophrenia. Two surveys were distributed to a local homeless population; the first survey was given prior to handing out the brochures and the second survey was given a week later after the participants had some time to read the information from the brochures. The data from the surveys supported the goal of the project by showing an increase in overall awareness of the diseases as well as an increase in behavioral changes that would lead to the increase of plausible prevention methods.
ContributorsBanuelos, Jason (Author) / Quaranta, Kimberly (Thesis director) / Szeli, Eva (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05