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- Creators: School of Life Sciences
Methods: Using PubMed, Medline, and CINAHL the search terms adolescents, depression, and yoga were searched for related articles. Articles were then excluded or included based on certain criteria. Focus was placed on articles written within the last 10 years as well as studies done on children within 10-19 years of age. Final articles underwent extraction for relevant information and comparisons were drawn between the studies.
Results: Final exclusion lead to a total of 5 suitable studies. Studies varied in styles of yoga performed and measurement scales used to assess depression. Populations of adolescents varied significantly as well. The majority of these studies showed significant improvement in depression symptoms when measuring from pre to post intervention. Similar improvements were also noted in anxiety symptoms and low self-esteem.
Conclusion: Data gathered indicated that yoga serves a suitable intervention for decreasing depression symptoms in adolescents. Additionally, there seems to be promising results regarding the viability of yoga as an intervention for decreasing symptoms of anxiety and increasing self-esteem. Despite, current promising results, there is need for more research to affirm the findings found in these articles to determine the long term effects of yoga interventions.
Adaptive therapy utilizes competitive interactions between resistant and sensitive cells by keeping some sensitive cells to control tumor burden with the aim of increasing overall survival and time to progression. The use of adaptive therapy to treat breast cancer, ovarian cancer, and pancreatic cancer in preclinical models has shown significant results in controlling tumor growth. The purpose of this thesis is to draft a protocol to study adaptive therapy in a preclinical model of breast cancer on MCF7, estrogen receptor-positive, cells that have evolved resistance to fulvestrant and palbociclib (MCF7 R). In this study, we used two protocols: drug dose adjustment and intermittent therapy. The MCF7 R cell lines were injected into the mammary fat pads of 11-month-old NOD/SCID gamma (NSG) mice (18 mice) which were then treated with gemcitabine.<br/>The results of this experiment did not provide complete information because of the short-term treatments. In addition, we saw an increase in the tumor size of a few of the treated mice, which could be due to the metabolism of the drug at that age, or because of the difference in injection times. Therefore, these adaptive therapy protocols on hormone-refractory breast cancer cell lines will be repeated on young, 6-week old mice by injecting the cell lines at the same time for all mice, which helps the results to be more consistent and accurate.
Background and Purpose: Meditative movement has become a common non-clinical intervention to address physical and mental ailments. This has been demonstrated by the “2012 National Health Interview Survey, [which states that] the use of yoga, tai chi, and qi gong has been increasing for over a decade and has nearly doubled from 2002 to 2012” (Green, n.d.). This overarching category includes the following practices: Yoga, Tai Chi, and Qigong. However, further research needs to be done into what ingredients constitute meditative movement and relay powerful effects such as lowering anxiety, depression, and/or blood pressure etc. for practitioners of the exercise. This paper will detail how the Meditative Movement Component Identification Tool (MCCIT) was developed and how a preliminary test of the MMCIT resulted in four overall components. This tool will serve as an instrument to assess the fidelity of meditative movement studies in the future. Methods: The MCCIT categories were extracted and chosen from a literature review of current articles on qigong, tai chi, and yoga, and overall meditative movement. There was a focus on articles that outlined ingredients significant for the type of exercise. Then the twelve selected components were reviewed using videos that were small 3–5-minute digital nuggets of meditative movement. Results: In a components analysis of the MMCIT, three factors: mind and body fluidity (α=.656) , breath (α=.991), inner calm (α=.760), and one potential factor: movement perception (α=.351) arose. Mind and body fluidity, breath, and inner calm subscales show item reliability, but movement perception needs further investigation. Conclusion: Mind and body fluidity, breath, and inner calm subscales show strong potential for being part of a tool used to ensure there is delivery of a meditative movement in an intervention with it in the protocol. However, the movement perception subscale needs to be reworked. The presence of nature and energy in meditative movement need to be further explored in a study with more participants, as well.
This paper will serve as a review of relevant scleractinian coral biology and genetics, discuss the ecological and biological impacts of growth anomalies in scleractinians, discuss the importance of studying this phenomena in terms of conservation, outline and discuss the processes undertaken to elucidate possible genetic markers of the growth anomalies, as well as discuss growth anomalies within the context of other coral disease and the anthropocene to add clarity no the subject to the oncological discussion taking place around such anomalies.