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In the search for chemical biosensors designed for patient-based physiological applications, non-invasive diagnostic approaches continue to have value. The work described in this thesis builds upon previous breath analysis studies. In particular, it seeks to assess the adsorptive mechanisms active in both acetone and ethanol biosensors designed for

In the search for chemical biosensors designed for patient-based physiological applications, non-invasive diagnostic approaches continue to have value. The work described in this thesis builds upon previous breath analysis studies. In particular, it seeks to assess the adsorptive mechanisms active in both acetone and ethanol biosensors designed for breath analysis. The thermoelectric biosensors under investigation were constructed using a thermopile for transduction and four different materials for biorecognition. The analytes, acetone and ethanol, were evaluated under dry-air and humidified-air conditions. The biosensor response to acetone concentration was found to be both repeatable and linear, while the sensor response to ethanol presence was also found to be repeatable. The different biorecognition materials produced discernible thermoelectric responses that were characteristic for each analyte. The sensor output data is presented in this report. Additionally, the results were evaluated against a mathematical model for further analysis. Ultimately, a thermoelectric biosensor based upon adsorption chemistry was developed and characterized. Additional work is needed to characterize the physicochemical action mechanism.
ContributorsWilson, Kimberly (Author) / Guilbeau, Eric (Thesis advisor) / Pizziconi, Vincent (Thesis advisor) / LaBelle, Jeffrey (Committee member) / Arizona State University (Publisher)
Created2011
Description
The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical engineering concepts. The gameplay provides fast paced, exciting, and mildly addicting rooms that the player must battle and survive through,

The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical engineering concepts. The gameplay provides fast paced, exciting, and mildly addicting rooms that the player must battle and survive through, followed by an engineering puzzle that must be solved in order to advance to the next room. The objective of this project was to introduce the core concepts of BME to prospective students, rather than attempt to teach an entire BME curriculum. Based on user testing at various phases in the project, we concluded that the gameplay was engaging enough to keep most users' interest through the educational puzzles, and the potential for expanding this project to reach an even greater audience is vast.
ContributorsNitescu, George (Co-author) / Medawar, Alexandre (Co-author) / Spano, Mark (Thesis director) / LaBelle, Jeffrey (Committee member) / Guiang, Kristoffer (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
Volume depletion can lead to migraines, dizziness, and significant decreases in a subject's ability to physically perform. A major cause of volume depletion is dehydration, or loss in fluids due to an imbalance in fluid intake to fluid excretion. Because proper levels of hydration are necessary in order to maintain

Volume depletion can lead to migraines, dizziness, and significant decreases in a subject's ability to physically perform. A major cause of volume depletion is dehydration, or loss in fluids due to an imbalance in fluid intake to fluid excretion. Because proper levels of hydration are necessary in order to maintain both short and long term health, the ability to monitor hydration levels is growing in clinical demand. Although devices capable of monitoring hydration level exist, these devices are expensive, invasive, or inaccurate and do not offer a continuous mode of measurement. The ideal hydration monitor for consumer use needs to be characterized by its portability, affordability, and accuracy. Also, this device would need to be noninvasive and offer continuous hydration monitoring in order to accurately assess fluctuations in hydration data throughout a specified time period. One particular method for hydration monitoring that fits the majority of these criteria is known as bioelectric impedance analysis (BIA). Although current devices using BIA do not provide acceptable levels of accuracy, portability, or continuity in data collection, BIA could potentially be modified to fit many, if not all, desired customer specifications. The analysis presented here assesses the viability of using BIA as a new standard in hydration level measurement. The analysis uses data collected from 22 subjects using an existing device that employs BIA. A regression derived for estimating TBW based on the parameters of age, weight, height, sex, and impedance is presented. Using impedance data collected for each subject, a regression was also derived for estimating impedance based on the factors of age, weight, height, and sex. The derived regression was then used to calculate a new impedance value for each subject, and these new impedance values were used to estimate TBW. Through a paired-t test between the TBW values derived by using the direct measurements versus the calculated measurements of impedance, the two samples were found to be comparable. Considerations for BIA as a noninvasive measurement of hydration are discussed.
ContributorsTenorio, Jorge Antonio (Author) / LaBelle, Jeffrey (Thesis director) / Pizziconi, Vincent (Committee member) / Spano, Mark (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor) / Harrington Bioengineering Program (Contributor)
Created2013-05
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Description
Suction stabilized floats have been implemented into a variety of applications such as supporting wind turbines in off-shore wind farms and for stabilizing cargo ships. This thesis proposes an alternative use for the technology in creating a system of suction stabilized floats equipped with real time location modules to hel

Suction stabilized floats have been implemented into a variety of applications such as supporting wind turbines in off-shore wind farms and for stabilizing cargo ships. This thesis proposes an alternative use for the technology in creating a system of suction stabilized floats equipped with real time location modules to help first responders establish a localized coordinate system to assist in rescues. The floats create a stabilized platform for each anchor module due to the inverse slack tank effect established by the inner water chamber. The design of the float has also been proven to be stable in most cases of amplitudes and frequencies ranging from 0 to 100 except for when the frequency ranges from 23 to 60 Hz for almost all values of the amplitude. The modules in the system form a coordinate grid based off the anchors that can track the location of a tag module within the range of the system using ultra-wideband communications. This method of location identification allows responders to use the system in GPS denied environments. The system can be accessed through an Android app with Bluetooth communications in close ranges or through internet of things (IoT) using a module as a listener, a Raspberry Pi and an internet source. The system has proven to identify the location of the tag in moderate ranges with an approximate accuracy of the tag location being 15 cm.
ContributorsDye, Michaela (Author) / Redkar, Sangram (Thesis advisor) / Sugar, Thomas (Committee member) / Rogers, Bradley (Committee member) / Arizona State University (Publisher)
Created2020
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Description
There has been a decrease in the fertility rate over the years due to today’s younger generation facing more pressure in the workplace and their personal lives. With an aging population, more and more older people with limited mobility will require nursing care for their daily activities. There are several

There has been a decrease in the fertility rate over the years due to today’s younger generation facing more pressure in the workplace and their personal lives. With an aging population, more and more older people with limited mobility will require nursing care for their daily activities. There are several applications for wearable sensor networks presented in this paper. The study will also present a motion capture system using inertial measurement units (IMUs) and a pressure-sensing insole with a control system for gait assistance using wearable sensors. This presentation will provide details on the implementation and calibration of the pressure-sensitive insole, the IMU-based motion capture system, as well as the hip exoskeleton robot. Furthermore, the estimation of the Ground Reaction Force (GRF) from the insole design and implementation of the motion tracking using quaternion will be discussed in this document.
ContributorsLi, Xunguang (Author) / Redkar, Sangram (Thesis advisor) / Sugar, Thomas (Committee member) / Subramanian, Susheelkumar (Committee member) / Arizona State University (Publisher)
Created2022
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Description
This work endeavors to lay a solid foundation for the exploration and the considerations of exoskeletons, exosuits, and medical devices concerning proprioceptive feedback. This investigation is situated at the nexus of engineering, neuroscience, and rehabilitation medicine, striving to cultivate a holistic understanding of how mechanical augmentation, interfaced synergistically with human

This work endeavors to lay a solid foundation for the exploration and the considerations of exoskeletons, exosuits, and medical devices concerning proprioceptive feedback. This investigation is situated at the nexus of engineering, neuroscience, and rehabilitation medicine, striving to cultivate a holistic understanding of how mechanical augmentation, interfaced synergistically with human proprioception, can foster enhanced mobility and safety. This is especially pertinent for individuals with compromised motor functions.British Neurologist Oliver Wolf Sacks in 1985 published “The Man who Mistook His Wife for a Hat” a series of his most memorable neurological case describing the brain's strangest pathways. One of these cases is “The Disembodied Lady”, Christina a 27-year-old woman that lost entirely the sense of proprioception due to polyneuropathy. This caused her to not be able to control her body, and she declares that “I feel the wind on my arms and face, and then I know, faintly, I have arms and a face. It’s not the real thing, but it’s something—it lifts this horrible, dead veil for a while. ” Finally, she was able to control her body using vision alone. Dr. Sacks introduced, for the first time, the importance of proprioception, as the sense of position of body parts relative to other parts of the body, to western culture. This document’s mission is to identify unexplored concepts in the literature regarding exoskeletons, wearables and assistive technology and a user’s proprioception, embodiment and utilization when wearing devices. Dr. Philipp Beckerle suggests the need to research the connections between wearable hardware and human sense of proprioception. He also emphasizes the need for functional assessment protocols for wearables devices and the role of embodiment. He criticizes the current commercially available upper-limb prostheses since they only restore limited functions and therefore impede embodiment. This document’s goal is to identify operative solutions through the adaptation of existing technologies and to use effective solutions to improve the quality of life of people suffering from pathologies or traumatic injuries.
ContributorsVignola, Claudio (Author) / Sugar, Thomas (Thesis advisor) / Redkar, Sangram (Committee member) / McDaniels, Troy (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Fine control of standing postural balance is essential for completing various tasks in daily activities, which might be compromised when interacting with dynamically challenging environments (e.g., moving ground). Among various biofeedback to improve postural balance control, vibrotactile feedback has an advantage of providing supplementary information about balance control without disturbing

Fine control of standing postural balance is essential for completing various tasks in daily activities, which might be compromised when interacting with dynamically challenging environments (e.g., moving ground). Among various biofeedback to improve postural balance control, vibrotactile feedback has an advantage of providing supplementary information about balance control without disturbing other core functions (e.g., seeing and hearing). This paper investigated the effectiveness of a waist vibrotactile feedback device to improve postural control during standing balance on a dynamically moving ground simulated by a robotic balance platform. Four vibration motors of the waist device applied vibration feedback in the anterior-posterior and medio-lateral direction based on the 2-dimensional sway angle, measured by an inertia measurement unit. Experimental results with 15 healthy participants demonstrated that the waist vibrotactile feedback is effective in improving postural control, evidenced by improvements in center-of-mass and center-of-pressure stability measures. In addition, this study confirmed the effectiveness of the waist vibrotactile feedback in improving standing balance control even under muscle fatigue induced by lower body exercise. The study further confirmed that the waist feedback is more effective in people with lower baseline balance performance in both normal and fatigue conditions.
ContributorsJo, Kwanghee (Author) / Lee, Hyunglae (Thesis advisor) / Sugar, Thomas (Committee member) / Peterson, Daniel (Committee member) / Arizona State University (Publisher)
Created2022
Description

Cornhole, traditionally seen as tailgate entertainment, has rapidly risen in popularity since the launching of the American Cornhole League in 2016. However, it lacks robust quality control over large tournaments, since many of the matches are scored and refereed by the players themselves. In the past, there have been issues

Cornhole, traditionally seen as tailgate entertainment, has rapidly risen in popularity since the launching of the American Cornhole League in 2016. However, it lacks robust quality control over large tournaments, since many of the matches are scored and refereed by the players themselves. In the past, there have been issues where entire competition brackets have had to be scrapped and replayed because scores were not handled correctly. The sport is in need of a supplementary scoring solution that can provide quality control and accuracy over large matches where there aren’t enough referees present to score games. Drawing from the ACL regulations as well as personal experience and testimony from ACL Pro players, a list of requirements was generated for a potential automatic scoring system. Then, a market analysis of existing scoring solutions was done, and it found that there are no solutions on the market that can automatically score a cornhole game. Using the problem requirements and previous attempts to solve the scoring problem, a list of concepts was generated and evaluated against each other to determine which scoring system design should be developed. After determining that the chosen concept was the best way to approach the problem, the problem requirements and cornhole rules were further refined into a set of physical assumptions and constraints about the game itself. This informed the choice, structure, and implementation of the algorithms that score the bags. The prototype concept was tested on their own, and areas of improvement were found. Lastly, based on the results of the tests and what was learned from the engineering process, a roadmap was set out for the future development of the automatic scoring system into a full, market-ready product.

ContributorsGillespie, Reagan (Author) / Sugar, Thomas (Thesis director) / Li, Baoxin (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
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Description
With the extensive technological progress made in the areas of drives, sensors and processing, exoskeletons and other wearable devices have become more feasible. However, the stringent requirements in regards to size and weight continue to exert a strong influence on the system-wide design of these devices and present many obstacles

With the extensive technological progress made in the areas of drives, sensors and processing, exoskeletons and other wearable devices have become more feasible. However, the stringent requirements in regards to size and weight continue to exert a strong influence on the system-wide design of these devices and present many obstacles to a successful solution. On the other hand, while the area of controls has seen a significant amount of progress, there also remains a large potential for improvements. This dissertation approaches the design and control of wearable devices from a systems perspective and provides a framework to successfully overcome the often-encountered obstacles with optimal solutions. The electronics, drive and control system design for the HeSA hip exoskeleton project and APEx hip exoskeleton project are presented as examples of how this framework is used to design wearable devices. In the area of control algorithms, a real-time implementation of the Fast Fourier Transform (FFT) is presented as an alternative approach to extracting amplitude and frequency information of a time varying signal. In comparison to the peak search method (PSM), the FFT allows extracting basic gait signal information at a faster rate because time windows can be chosen to be less than the fundamental gait frequency. The FFT is implemented on a 16-bit processor and the results show the real-time detection of amplitude and frequency coefficients at an update rate of 50Hz. Finally, a novel neural networks based approach to detecting human gait activities is presented. Existing neural networks often require vast amounts of data along with significant computer resources. Using Neural Ordinary Differential Equations (Neural ODEs) it is possible to distinguish between seven different daily activities using a significantly smaller data set, lower system resources and a time window of only 0.1 seconds.
ContributorsBoehler, Alexander (Author) / Sugar, Thomas (Thesis advisor) / Redkar, Sangram (Committee member) / Hollander, Kevin (Committee member) / Arizona State University (Publisher)
Created2021
Description

The creative project was to create a working prototype kit that can teach multiple lessons of the curriculum that the schools or individual families could purchase. The curriculum would be centered on the engineering and science curriculum that is introduced from fourth to sixth grade classes. By creating an interactive

The creative project was to create a working prototype kit that can teach multiple lessons of the curriculum that the schools or individual families could purchase. The curriculum would be centered on the engineering and science curriculum that is introduced from fourth to sixth grade classes. By creating an interactive kit with curriculum that the students could individualize and use for multiple lessons, the goal is to get them more engaged in the material. The project would consist of a week-long project kit that will introduce different engineering topics for three to four days of the week with mini projects and a final project that pieces together the topics they learned. The biggest take away from the project was how to best get user feedback and fast track the IRB process. The IRB process for a project focusing on minors and teachers will cause some catches in the process. Included is a discussion on the IRB process for a project like this and how to best go through or avoid IRB to ensure the project can progress, while still gathering valuable information.

ContributorsHeun, Jade (Author) / Aukes, Daniel (Thesis director) / Sugar, Thomas (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor)
Created2022-05