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- All Subjects: healthcare
- Creators: Harrington Bioengineering Program
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Description
Many developing countries do not have health care systems that can afford technological biomedical devices or supplies to make such devices operational. To fill this void, nonprofit organizations, like Project C.U.R.E., recondition retired biomedical instrumentation so they can send medical supplies to help these developing countries. One of the issues with this is that sometimes the devices are unusable because components or expendable supplies are not available (Bhadelia). This issue has also been shown in the Impact Evaluations that Project C.U.R.E. receives from the clinics that explain the reasons why certain devices are no longer in use. That need underlies the idea on which this honors thesis has come into being. The purpose of this honors project was to create packing lists for biomedical instruments that Project C.U.R.E. recycles. This packing list would decrease the likelihood of important items being forgotten when sending devices. If an extra fuse, battery, light bulb, cuff or transducer is the difference between a functional or a nonfunctional medical device, such a list would be of benefit to Project C.U.R.E and these developing countries. In order to make this packing list, manuals for each device were used to determine what supplies were required, what was necessary for cleaning, and what supplies were desirable but functionally optional. This list was then added into a database that could be easily navigated and could help when packing up boxes for a shipment. The database also makes adding and editing the packing list simple and easy so that as Project C.U.R.E. gets more donated devices the packing list can grow.
ContributorsGraft, Kelsey Anne (Author) / Coursen, Jerry (Thesis director) / Walters, Danielle (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
In the medical industry, there have been promising advances in the increase of new types of healthcare to the public. As of 2015, there was a 98% Premarket Approval rate, a 38% increase since 2010. In addition, there were 41 new novel drugs approved for clinical usage in 2014 where the average in the previous years from 2005-2013 was 25. However, the research process towards creating and delivering new healthcare to the public remains remarkably inefficient. It takes on average 15 years, over $900 million by one estimate, for a less than 12% success rate of discovering a novel drug for clinical usage. Medical devices do not fare much better. Between 2005-2009, there were over 700 recalls per year. In addition, it takes at minimum 3.25 years for a 510(k) exempt premarket approval. Plus, a time lag exists where it takes 17 years for only 14% of medical discoveries to be implemented clinically. Coupled with these inefficiencies, government funding for medical research has been decreasing since 2002 (2.5% of Gross Domestic Product) and is predicted to be 1.5% of Gross Domestic Product by 2019. Translational research, the conversion of bench-side discoveries to clinical usage for a simplistic definition, has been on the rise since the 1990s. This may be driving the increased premarket approvals and new novel drug approvals. At the very least, it is worth considering as translational research is directly related towards healthcare practices. In this paper, I propose to improve the outcomes of translational research in order to better deliver advancing healthcare to the public. I suggest Best Value Performance Information Procurement System (BV PIPS) should be adapted in the selection process of translational research projects to fund. BV PIPS has been shown to increase the efficiency and success rate of delivering projects and services. There has been over 17 years of research with $6.3 billion of projects and services delivered showing that BV PIPS has a 98% customer satisfaction, 90% minimized management effort, and utilizes 50% less manpower and effort. Using University of Michigan \u2014 Coulter Foundation Program's funding process as a baseline and standard in the current selection of translational research projects to fund, I offer changes to this process based on BV PIPS that may ameliorate it. As concepts implemented in this process are congruent with literature on successful translational research, it may suggest that this new model for selecting translational research projects to fund will reduce costs, increase efficiency, and increase success. This may then lead to more Premarket Approvals, more new novel drug approvals, quicker delivery time to the market, and lower recalls.
ContributorsDel Rosario, Joseph Paul (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
As the complexity of healthcare continues to rise, the need for change in healthcare delivery is more prominent than ever. One strategy identified by the World Health Organization (WHO) for responding to these increasing complexities is the use of interprofessional practice and education to improve patient outcomes, reduce costs, and enhance the patient experience of care (Triple Aim). Interprofessional collaboration among diverse disciplines is evident on the Phoenix Biomedical Campus, integrating a wide variety of institutions and multiple health profession programs; and at the Student Health Outreach for Wellness (SHOW) free clinic, -- a successful tri-university, student-led, faculty mentored, and community-based model of interprofessional learning and care -- based in downtown Phoenix. This project conducted a comparative analysis of interprofessional components of 6 different clinical models in order to provide recommendations for best practice implementation. These models were chosen based on availability of research on interprofessionalism with their clinics. As a result, three recommendations were offered to the SHOW clinic for consideration in their efforts to improve both patient and educational outcomes. Each recommendation was intentionally formulated for its capacity to increase: interprofessionalism and collaboration between multiple disciplines pertaining to healthcare, among healthcare professionals to promote positive patient and educational outcomes. These recommendations include implementing an interprofessional education (IPE) course as a core component in an academic program's curriculum, offering faculty and professional development opportunities for faculty and mentors immersed in the interprofessional clinics, and utilization of simulation centers. Further studies will be needed to evaluate the impact these specific interventions, if adopted, on patient and educational outcomes.
ContributorsMousa, Mohammad (Co-author) / Mousa, Bakir (Co-author) / Johnson, Ross (Co-author) / Harrell, Liz (Thesis director) / Saewert, Karen (Committee member) / Harrington Bioengineering Program (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
This thesis project discusses the transitions of the physician profession and their struggle to maintain autonomy throughout American History until approximately the 1980's. Included in the historical account of the physician profession, is the development of the American Hospital System and its origins working under the physician profession. As history progresses from 1760 on, what comes to light is a cyclical struggle for physicians to remain independent from the corporations, while using them to gain social and economic prestige. This work focuses on how the establishment of private practice in the United States has lead to the current system in place today, illustrating a long fight for control of the medical field that still rages on today. As physicians gained power and autonomy in the medical field during the 20th century, constant attempts of government intervention can be seen within the convoluted history of this professional field. The rise of corporate healthcare, that works in tandem with private physicians, was a critical period in forgotten American History that subsequently allowed physicians to increase their stranglehold on the medical service industry. The goal of this research was to establish a better understanding of American Medicine's history to better tackle the new problems we face today. As America transitions to a period of public health outcry, it is important to establish a somewhat linear rendition of a mostly untold history that directly impacts the lives of every citizen in this country. This work attempts to mend the broken pieces of that history to give light to how healthcare evolved into what it is today.
ContributorsParkhurst, Erik Lewis (Author) / Tyler, William (Thesis director) / Coursen, Jerry (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
Incorporating sustainability education in primary healthcare practice is an important step toward promoting sustainability in the US healthcare system. This health strategy is also consistent with a renewed focus of the US healthcare system, mainly prompted by the Affordable Healthcare Act of 2010, toward preventive care and patient wellness. The major challenge, however, is an effective implementation of sustainability education in the healthcare industry. This honors thesis project developed a sustainability education model, in which primary healthcare providers or the physicians educated the patients about sustainability and its connection to public health issues. The main purpose of this thesis project is to analyze the effectiveness of this sustainability education model and to evaluate its impact on the individuals and households in terms of sustainable attitudes and practices. The study was conducted with 26 parents of newborn babies at Estrella Pediatrics PC using a classic randomized control-group pretest-posttest design. The Pre- and Post-Surveys were completed to evaluate change in their knowledge and attitudes toward sustainability practices covered in the sustainability education model. In the research, the relationships between sustainability-related issues and their negative impacts on the health of human beings were established in the sustainability education pamphlet provided to the physicians, which they shared with the patients during the wellness visits. This pamphlet focused on waste management, air pollution, and locally grown food. Moreover, samples of environmentally-friendly diapers were given to the study respondents to complement this education. The study demonstrated positive trends with the intervention protocol, though the level of statistical significance was marginal. More specifically, it was observed that the respondents placed the highest significance on the education provided by the pediatricians. Interestingly, the receipt of the diaper samples by itself did not generate any significant effect. However, the education provided by the physician and the pamphlet coupled with the diaper gave very positive results. In conclusion, physician led sustainability education has significant potential in promoting sustainability in primary healthcare practice, and further inquiry should be pursued.
ContributorsQuintero Cervantes, Laura Beatriz (Author) / Shrestha, Milan (Thesis director) / Boone, Christopher (Committee member) / Thunderbird School of Global Management (Contributor) / W. P. Carey School of Business (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Biosimilar pharmaceuticals are new lower-cost drugs awaiting large-scale approval within the United States (U.S). Biosimilar pharmaceuticals or simply biosimilars, are complex, large-molecule, and biologically-derived drugs that are deemed molecularly similar to currently approved reference biologics. Biologics and biosimilars both treat a wide range of conditions with no clinically meaningful difference between them. However, numerous states, with help from large pharmaceutical companies lobbying, are passing legislation complicating the prescribing and dispensing process for biosimilars by mandating a "notification" or "communication" requirement. The notification requirement requires pharmacists to contact prescribers when dispensing an interchangeable biosimilar in place of its reference biologic. This type of mandate is not only unprecedented in current U.S. pharmaceutical law, but it also incentivizes pharmacists to dispense more expensive biologics in place of biosimilars. The notification or communication requirement also falsely gives consumers the appearance that biosimilars are more dangerous in comparison to other types of biological medicines. These two factors, pharmacist hesitation and consumer distrust, serve as barriers to successful biosimilar market entry. High research and development costs and forecasted poor sales inhibit biosimilar companies from making the investment in innovating new drugs. The lack of investment in research and development prevents new biosimilars from entering the market to compete with currently approved biologics. In turn, current biosimilar legislation is reducing pharmaceutical competition and increasing drug prices. Information Measurement Theory supports the notion that in climates without competition (caused by a lack of transparency) sparks low quality and high costs. Transparency and improved biosimilar market conditions can be achieved through repealing the large pharmaceutical company backed notification requirement.
ContributorsFelthouse, Karis Renee (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / School of Politics and Global Studies (Contributor) / School of Film, Dance and Theatre (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
As educational tactics circulate globally, so too does the prospect of understanding sustainability amongst informed individuals and what it means for our society. Just in the past few decades, the environmental movement has changed the way in which people think about their own impact upon the planet. It is becoming a facet of common knowledge for society to realize the potential detriment of their actions, and for this, we should be grateful. However, there is much work to be done regarding all aspects of sustainability and environmental crises. This paper offers a look into the world of sustainable sunscreen usage, something that is not often thought about as an aspect of sustainable consideration. The task of this research opportunity was to examine a sample of survey respondents and connect their responses from 15 questions to different hypotheses. Alongside the discussion of sunscreen filters damaging sensitive ocean ecosystems, this research also looks into the overall importance of sunscreen for one’s health and the ways in which it can be used safely. My hope is that readers will realize the value of using sunscreen on a daily basis and become better informed of sustainability challenges and healthcare disparities.
ContributorsPeretic, Emilee (Author) / Westerhoff, Paul (Thesis director) / Goebel, Janna (Committee member) / Barrett, The Honors College (Contributor) / School of Sustainability (Contributor) / The Sidney Poitier New American Film School (Contributor)
Created2023-05
Description
My thesis explores the development of a new treatment option for children with Amblyopia. I did a lot of research into existing treatment options as well as interviewing patients and their parents do figure out why these treatments were not working. I interviewed a pediatric ophthalmologist to better understand this condition from their point of view. I also did a competitive analysis to see who else was in this marketplace. From the insights I gathered I was able to create a user journey map to see where the most problems arose during the experience from Diagnoses to end of treatment. With this research I was able to design a new treatment plan that was focused on empathizing with the user. I developed several concepts ranging from lo-fi to blue sky. I tested these concepts by making models and getting feedback from the user. I developed the actual design of the glasses through sketching and model making. I tested the ergonomics and design with the help of my classmates. The solution is a combination of smart glasses and an app. The smart glasses function as a replacement of traditional and popular patching by dimming one lens to block vision to the strong eye. This forces the weak eye to be used. The app is used to encourage kids to use the glasses more often through games and challenges. The challenges give rewards for wearing the glasses for an extended period of time. The games are used to increase of effectiveness of the treatment. Research showed that video games like Tetris forces the eye to focus and be used more than in daily life. This solution makes the treatment experience positive instead of negative as it was with other treatments.
ContributorsMeling, Erlend Henry Olav (Author) / Shin, Dosun (Thesis director) / Feil, Magnus (Committee member) / School of Sustainability (Contributor) / The Design School (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Asthma is one of the most common chronic conditions in the United States, being diagnosed in over 20 million Americans. The condition is even more common among young children, and their academic performance and ability to attend school can be negatively impacted by poorly-managed asthma. Digital therapeutics are therapeutic interventions driven by high quality software programs to prevent, manage, or treat a medical disorder or disease. Technology in the healthcare space is rapidly improving, and smart devices are becoming more common everyday. How can digital therapeutics and evolving technology be implemented to make life easier for those that suffer from asthma and chronic obstructive pulmonary disease? My research seeks to answer the overarching question: How might we improve the day-to-day experience of children with asthma? Airie is a system of devices and products that educate both asthmatic children and their parents about the condition, facilitate self-monitoring and asthma management skills, and improve overall quality of life.
ContributorsChen, Jane Jialin (Author) / Shin, Dosun (Thesis director) / Feil, Magnus (Committee member) / The Design School (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In the US, underrepresented racial and ethnic minorities receive less than adequate health care in comparison to White Americans. This is attributed to multiple factors, including the long history of structural racism in the US and in the medical field in particular. A factor that is still prevalent today is the lack of diversity within the healthcare workforce. Racial and ethnic minorities are underrepresented in most healthcare occupations. Moreover, many physicians may continue to harbor implicit biases that may interfere with giving adequate care to patients of different backgrounds. We propose that diversity in healthcare should be increased through educational programs and a revamp of existing systems such as medical schools. The increased diversity would mitigate some of the health disparities that exist amongst minorities, as medical professionals are more likely to give adequate care to those who are members of the same community. Increased diversity would also help to increase the cultural competency of physicians as a whole.
ContributorsLopez, Adriana (Author) / Webb, Linden (Co-author) / Martin, Thomas (Thesis director) / Feagan, Mathieu (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2022-05