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Description
Parallel Monte Carlo applications require the pseudorandom numbers used on each processor to be independent in a probabilistic sense. The TestU01 software package is the standard testing suite for detecting stream dependence and other properties that make certain pseudorandom generators ineffective in parallel (as well as serial) settings. TestU01 employs

Parallel Monte Carlo applications require the pseudorandom numbers used on each processor to be independent in a probabilistic sense. The TestU01 software package is the standard testing suite for detecting stream dependence and other properties that make certain pseudorandom generators ineffective in parallel (as well as serial) settings. TestU01 employs two basic schemes for testing parallel generated streams. The first applies serial tests to the individual streams and then tests the resulting P-values for uniformity. The second turns all the parallel generated streams into one long vector and then applies serial tests to the resulting concatenated stream. Various forms of stream dependence can be missed by each approach because neither one fully addresses the multivariate nature of the accumulated data when generators are run in parallel. This dissertation identifies these potential faults in the parallel testing methodologies of TestU01 and investigates two different methods to better detect inter-stream dependencies: correlation motivated multivariate tests and vector time series based tests. These methods have been implemented in an extension to TestU01 built in C++ and the unique aspects of this extension are discussed. A variety of different generation scenarios are then examined using the TestU01 suite in concert with the extension. This enhanced software package is found to better detect certain forms of inter-stream dependencies than the original TestU01 suites of tests.
ContributorsIsmay, Chester (Author) / Eubank, Randall (Thesis advisor) / Young, Dennis (Committee member) / Kao, Ming-Hung (Committee member) / Lanchier, Nicolas (Committee member) / Reiser, Mark R. (Committee member) / Arizona State University (Publisher)
Created2013
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Description
By the von Neumann min-max theorem, a two person zero sum game with finitely many pure strategies has a unique value for each player (summing to zero) and each player has a non-empty set of optimal mixed strategies. If the payoffs are independent, identically distributed (iid) uniform (0,1) random

By the von Neumann min-max theorem, a two person zero sum game with finitely many pure strategies has a unique value for each player (summing to zero) and each player has a non-empty set of optimal mixed strategies. If the payoffs are independent, identically distributed (iid) uniform (0,1) random variables, then with probability one, both players have unique optimal mixed strategies utilizing the same number of pure strategies with positive probability (Jonasson 2004). The pure strategies with positive probability in the unique optimal mixed strategies are called saddle squares. In 1957, Goldman evaluated the probability of a saddle point (a 1 by 1 saddle square), which was rediscovered by many authors including Thorp (1979). Thorp gave two proofs of the probability of a saddle point, one using combinatorics and one using a beta integral. In 1965, Falk and Thrall investigated the integrals required for the probabilities of a 2 by 2 saddle square for 2 × n and m × 2 games with iid uniform (0,1) payoffs, but they were not able to evaluate the integrals. This dissertation generalizes Thorp's beta integral proof of Goldman's probability of a saddle point, establishing an integral formula for the probability that a m × n game with iid uniform (0,1) payoffs has a k by k saddle square (k ≤ m,n). Additionally, the probabilities of a 2 by 2 and a 3 by 3 saddle square for a 3 × 3 game with iid uniform(0,1) payoffs are found. For these, the 14 integrals observed by Falk and Thrall are dissected into 38 disjoint domains, and the integrals are evaluated using the basic properties of the dilogarithm function. The final results for the probabilities of a 2 by 2 and a 3 by 3 saddle square in a 3 × 3 game are linear combinations of 1, π2, and ln(2) with rational coefficients.
ContributorsManley, Michael (Author) / Kadell, Kevin W. J. (Thesis advisor) / Kao, Ming-Hung (Committee member) / Lanchier, Nicolas (Committee member) / Lohr, Sharon (Committee member) / Reiser, Mark R. (Committee member) / Arizona State University (Publisher)
Created2011
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Description
There are multiple mathematical models for alignment of individuals moving within a group. In a first class of models, individuals tend to relax their velocity toward the average velocity of other nearby neighbors. These types of models are motivated by the flocking behavior exhibited by birds. Another class of models

There are multiple mathematical models for alignment of individuals moving within a group. In a first class of models, individuals tend to relax their velocity toward the average velocity of other nearby neighbors. These types of models are motivated by the flocking behavior exhibited by birds. Another class of models have been introduced to describe rapid changes of individual velocity, referred to as jump, which better describes behavior of smaller agents (e.g. locusts, ants). In the second class of model, individuals will randomly choose to align with another nearby individual, matching velocities. There are several open questions concerning these two type of behavior: which behavior is the most efficient to create a flock (i.e. to converge toward the same velocity)? Will flocking still emerge when the number of individuals approach infinity? Analysis of these models show that, in the homogeneous case where all individuals are capable of interacting with each other, the variance of the velocities in both the jump model and the relaxation model decays to 0 exponentially for any nonzero number of individuals. This implies the individuals in the system converge to an absorbing state where all individuals share the same velocity, therefore individuals converge to a flock even as the number of individuals approach infinity. Further analysis focused on the case where interactions between individuals were determined by an adjacency matrix. The second eigenvalues of the Laplacian of this adjacency matrix (denoted ƛ2) provided a lower bound on the rate of decay of the variance. When ƛ2 is nonzero, the system is said to converge to a flock almost surely. Furthermore, when the adjacency matrix is generated by a random graph, such that connections between individuals are formed with probability p (where 0

1/N. ƛ2 is a good estimator of the rate of convergence of the system, in comparison to the value of p used to generate the adjacency matrix..

ContributorsTrent, Austin L. (Author) / Motsch, Sebastien (Thesis director) / Lanchier, Nicolas (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Division of Labor among social insects is frequently discussed in regards to the colony's worker population. However, before a colony achieves a worker population, a queen is required to perform all of the tasks necessary for her survival: foraging, building the colony, and brood care. A simple ODE model was

Division of Labor among social insects is frequently discussed in regards to the colony's worker population. However, before a colony achieves a worker population, a queen is required to perform all of the tasks necessary for her survival: foraging, building the colony, and brood care. A simple ODE model was developed through the use of a framework of replicator equations in dynamical environments to investigate how queen ants perform and distribute all of the tasks necessary for her and her colony's survival by incorporating individual internal thresholds and environmental stimulus. Modi�cations to the internal threshold, risk of performing the task, and the rate of increase of the environmental stimulus were also explored. Because of the simplicity of the model, it could also be used to measure the task performance of larger populations of social insects. However, the model has only been applied to the data collected from Pogonomyrmex barbatus single queen ants.
ContributorsKincade, Katherine Margaret (Author) / Kang, Yun (Thesis director) / Fewell, Jennifer (Committee member) / Lanchier, Nicolas (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
The deficiency of American primary and secondary schools as compared to schools worldwide has long been documented. The Teaching Gap highlights exactly where our problems might lie, and lays out a plan for how to deal with it. Progress would be slow, but tangible. Our country, however, seems to prefer

The deficiency of American primary and secondary schools as compared to schools worldwide has long been documented. The Teaching Gap highlights exactly where our problems might lie, and lays out a plan for how to deal with it. Progress would be slow, but tangible. Our country, however, seems to prefer vast and immediate overhauls that have historically failed (see: New math, etc.). If we had implemented the changes in The Teaching Gap in the decade in which it was written, we would be seeing results by now. Instead, every change we make gets reverted. The Common Core State Standards will prove over the next few years to be either another one of these attempts or a large step in the right direction. It might finally be the latter, as its creation was informed by practices that work best in every state in the US, as well as high- performing countries around the world.
ContributorsMcKee, Emily (Author) / Sande, V. Carla (Thesis director) / Ashbrook, Mark (Committee member) / Schroeder, Darcy (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Identifying associations between genotypes and gene expression levels using next-generation technology has enabled systematic interrogation of regulatory variation underlying complex phenotypes. Understanding the source of expression variation has important implications for disease susceptibility, phenotypic diversity, and adaptation (Main, 2009). Interest in the existence of allele-specific expression in autosomal genes evolved

Identifying associations between genotypes and gene expression levels using next-generation technology has enabled systematic interrogation of regulatory variation underlying complex phenotypes. Understanding the source of expression variation has important implications for disease susceptibility, phenotypic diversity, and adaptation (Main, 2009). Interest in the existence of allele-specific expression in autosomal genes evolved with the increased awareness of the important role that variation in non-coding DNA sequences can play in determining phenotypic diversity, and the essential role parent-of-origin expression has in early development (Knight, 2004). As new implications of high-throughput sequencing are conceived, it is becoming increasingly important to develop statistical methods tailored to large and formidably complex data sets in order to maximize the biological insights derived from next-generation sequencing experiments. Here, a Bayesian hierarchical probability model based on the beta-binomial distribution is proposed as a possible approach for quantifying allele-specific expression from whole genome (WGS) and whole transcriptome (RNA-seq) data. Pipeline for the analysis of WGS and RNA-seq data sets from ten samples was developed and implemented, while allele-specific expression (ASE) was quantified from both haplotypes using individuals heterozygous at the tested variants utilizing the described methodology. Both computational and statistical framework applied accurately quantified ASE, achieving high reproducibility of already described allele-specific genes in the literature. In conclusion, described methodology provides a solid starting point for quantifying allele specific expression across whole genomes.
ContributorsMalenica, Ivana (Author) / Craig, David (Thesis director) / Rosenberg, Michael (Committee member) / Szelinger, Szabolcs (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
The decline of honeybee colonies around the world has been linked to the presence of the Varroa destructor, a mite acting as a virus vector for the Acute Bee Paralysis Virus. We developed a model of the infestation of the Apis melliifera honeybee colony by the Acute Bee Paralysis Virus,

The decline of honeybee colonies around the world has been linked to the presence of the Varroa destructor, a mite acting as a virus vector for the Acute Bee Paralysis Virus. We developed a model of the infestation of the Apis melliifera honeybee colony by the Acute Bee Paralysis Virus, which is transmitted by the parasitic Varroa destructor. This is a four dimensional system of nonlinear ODE's for healthy and virus infected bees, total number of mites in the colony and number of mites that carry the virus. The Acute Bee Paralysis Virus can be transmitted between infected and uninfected bees, infected mite to adult bee, infected bee to phoretic mite, and reproductive mites to bee brood. This model is studied with analytical techniques deriving the conditions under which the bee colony can fight off an Acute Bee Paralysis Virus epidemic.
ContributorsDavis, Talia Lasandra (Author) / Kang, Yun (Thesis director) / Lanchier, Nicolas (Committee member) / Moore, Marianne (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
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DescriptionUnderstanding the evolution of opinions is a delicate task as the dynamics of how one changes their opinion based on their interactions with others are unclear.
ContributorsWeber, Dylan (Author) / Motsch, Sebastien (Thesis advisor) / Lanchier, Nicolas (Committee member) / Platte, Rodrigo (Committee member) / Armbruster, Dieter (Committee member) / Fricks, John (Committee member) / Arizona State University (Publisher)
Created2021
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Description
For fifty years, inquiry has attempted to capture how groups of people experience microaggression phenomena through multiple methodological and analytic applications grounded in psychology-influenced frameworks. Yet, despite theoretical advancements, the phenomenon has met criticisms trivializing its existence, falsifiability, and social significance. Unpacking possible interactive factors of a microaggressive moment invites

For fifty years, inquiry has attempted to capture how groups of people experience microaggression phenomena through multiple methodological and analytic applications grounded in psychology-influenced frameworks. Yet, despite theoretical advancements, the phenomenon has met criticisms trivializing its existence, falsifiability, and social significance. Unpacking possible interactive factors of a microaggressive moment invites a revisitation of the known and unknown pragmatic conditions that may produce and influence its discomforting situational “content.” This study employs an intentional, game-theoretic methodology based on brief, publicly-recorded, everyday conversation segments. Conversation segments of social interactions provide a means to conduct a mathematically-solid, computationally-tractable analysis of explaining what is happening during encounters where disability microaggressions are likely the result of partial (non)cooperation between communicators. Such analysis extends the microaggression research program (MRP) by: (1) proposing theoretical consequences for conversational repair phenomena, algorithmic programming, and experimental designs in negotiation research; and (2) outlining practical approaches for preventing microaggressions with new communication pedagogy, anti-oppression/de-escalation training programs, and calculable, focus-oriented psychotherapy. It concludes with an invitation for scholars to “be” in ambiguity so that they may speculate possible trajectories for the study of microaggressions as a communicative phenomenon.
ContributorsReutlinger, Corey Jon (Author) / de la Garza, Sarah Amira (Thesis advisor) / Alberts, Janet (Committee member) / Lanchier, Nicolas (Committee member) / Cherney, James L. (Committee member) / Arizona State University (Publisher)
Created2021
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Description
A leading crisis in the United States is the opioid use disorder (OUD) epidemic. Opioid overdose deaths have been increasing, with over 100,000 deaths due to overdose from April 2020 to April 2021. This dissertation presents two mathematical models to address illicit OUD (IOUD), treatment, and recovery within an epidemiological

A leading crisis in the United States is the opioid use disorder (OUD) epidemic. Opioid overdose deaths have been increasing, with over 100,000 deaths due to overdose from April 2020 to April 2021. This dissertation presents two mathematical models to address illicit OUD (IOUD), treatment, and recovery within an epidemiological framework. In the first model, individuals remain in the recovery class unless they relapse. Due to the limited availability of specialty treatment facilities for individuals with OUD, a saturation treat- ment function was incorporated. The second model is an extension of the first, where a casual user class and its corresponding specialty treatment class were added. Using U.S. population data, the data was scaled to a population of 200,000 to find parameter estimates. While the first model used the heroin-only dataset, the second model used both the heroin and all-illicit opioids datasets. Backward bifurcation was found in the first IOUD model for realistic parameter values. Additionally, bistability was observed in the second IOUD model with the heroin-only dataset. This result implies that it would be beneficial to increase the availability of treatment. An alarming effect was discovered about the high overdose death rate: by 2038, the disease-free equilibrium would be the only stable equilibrium. This consequence is concerning because although the goal is for the epidemic to end, it would be preferable to end it through treatment rather than overdose. The IOUD model with a casual user class, its sensitivity results, and the comparison of parameters for both datasets, showed the importance of not overlooking the influence that casual users have in driving the all-illicit opioid epidemic. Casual users stay in the casual user class longer and are not going to treatment as quickly as the users of the heroin epidemic. Another result was that the users of the all-illicit opioids were going to the recovered class by means other than specialty treatment. However, the relapse rates for those individuals were much more significant than in the heroin-only epidemic. The results above from analyzing these models may inform health and policy officials, leading to more effective treatment options and prevention efforts.
ContributorsCole, Sandra (Author) / Wirkus, Stephen (Thesis advisor) / Gardner, Carl (Committee member) / Lanchier, Nicolas (Committee member) / Camacho, Erika (Committee member) / Fricks, John (Committee member) / Arizona State University (Publisher)
Created2022