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DescriptionThis creative project provides documentation and an exploration of my interactions with individuals encountered while hitchhiking up the west coast.
ContributorsGerber, Evan Howard (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / W. P. Carey School of Business (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Though schizophrenia was categorized as a mental illness over 100 years ago, there is a plethora of knowledge that continues to perplex the scientific and medical community alike. This tragic mental disorder affects approximately 1% of the general population, and many of these individuals are homeless if left untreated. Each schizophrenia patient has a different set of symptoms, so all of these patients experience a variety of positive and negative symptoms. Negative symptoms are called so as they are in absence, and some examples include apathy, anhedonia, lack of motivation, reduced social drive, and reduced cognitive functioning. Positive behavior, on the other hand, is a change in behavior or thoughts such as visual or auditory hallucinations, delusions, confused thoughts, disorganized speech, and trouble concentrating. Because schizophrenia patients do not share the exact same set of symptoms, research in schizophrenia requires a tremendous amount of medical resources. Over the last few years, new studies have started in the field of schizophrenia involving proteomics, or the study of proteins and their function. This new frontier gives doctors and scientists alike a new opportunity to improve the quality of life of schizophrenia patients by providing a potential method through which patients would receive individualized treatment based on their specific symptoms.
ContributorsPeterson, Rozabel (Author) / Brian, Jennifer (Thesis director) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Tempe Town Lake is the site of fifteen years’ worth of chemical data collection by ASU researchers. In 2018 the dataSONDE, an instrument capable of measuring different water quality parameters every thirty minutes for a month at a time was installed in the lake. The SONDE has the potential to completely reduce the need for sampling by hand. Before the SONDE becomes the sole means of gathering data, it is important to verify its accuracy. In this study, the measurements gathered by the SONDE (pH, dissolved oxygen, temperature, conductivity and colored dissolved organic matter) were compared to measurements gathered using the verified methods from the past fifteen years.
ContributorsSauer, Elinor Rayne (Author) / Hartnett, Hilairy (Thesis director) / Glaser, Donald (Committee member) / Shock, Everett (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow it to go extended periods of time consuming little to no food. These adaptations also allow the body to recover quickly once food becomes available. They include changes in metabolism that allow different fuel sources to be used for energy, the storing of excess energy absorbed from food in the forms of glycogen and fat to be used in between meals, and a reduction in the basal metabolic rate in response to starvation, as well as physiological changes in the small intestines. Even in places where starvation is not a concern today, these adaptations are still important as they also have an effect on weight gain and dieting in addition to promoting survival when the body is in a starved state.
Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
ContributorsPhlipot, Stephanie Anne (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Enzyme Replacement Therapy (ERT) is a treatment often used for patients with disorders that affect the production of various enzymes within the body, such as Cystic Fibrosis and Fabry Disease. ERT involves the use of artificially-produced enzymes, which can be derived from humans, pigs, and bacteria. Generally, enzymes derived from porcine and bacterial sources are much less expensive and more accessible than those derived from a human source. This, and the ethical implications that porcine enzymes carry, make the decision of choosing treatment simple to some and complex to others. Ethically, human-derived enzymes are often considered more ethical, while not conflicting with religious beliefs and practices as porcine-derived enzymes do.
In order to further compare porcine and human-derived enzymes, a determination of the enzyme effectiveness was done via digestion simulation. The digestion for both the human and porcine-derived enzymes consisted of three steps: oral, gastric, and intestinal. After the digestion, the absorbance for each enzyme class as well as a dilution curve of the formula used was read and recorded. Using the standard dilution curve and the absorbance values for each unknown, the formula and thus enzyme concentration that was lost through the reaction was able to be calculated.
The effectiveness of both the human and porcine enzymes, determined by the percent of formula lost, was 18.2% and 19.7%, respectively, with an error of 0.6% from the spectrophotometer, and an error of about 10% from the scale used for measuring the enzymes. This error was likely due to the small mass required of the enzymes and can be prevented in the future by performing the experiment at a larger scale.
In order to further compare porcine and human-derived enzymes, a determination of the enzyme effectiveness was done via digestion simulation. The digestion for both the human and porcine-derived enzymes consisted of three steps: oral, gastric, and intestinal. After the digestion, the absorbance for each enzyme class as well as a dilution curve of the formula used was read and recorded. Using the standard dilution curve and the absorbance values for each unknown, the formula and thus enzyme concentration that was lost through the reaction was able to be calculated.
The effectiveness of both the human and porcine enzymes, determined by the percent of formula lost, was 18.2% and 19.7%, respectively, with an error of 0.6% from the spectrophotometer, and an error of about 10% from the scale used for measuring the enzymes. This error was likely due to the small mass required of the enzymes and can be prevented in the future by performing the experiment at a larger scale.
ContributorsBlevins, Brianna R (Author) / Martin, Thomas (Thesis director) / McILwraith, Heide (Committee member) / College of Integrative Sciences and Arts (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The Scientist in Me is an original children’s book, authored by Annmarie Barton and illustrated by Alison Lane, that explores the lives and specialties of five remarkable scientists from historically underrepresented backgrounds: Mary Anning, James Pollack, Temple Grandin, Percy Lavon Julian, and Ayah Bdeir. In the book, each scientist has an “Experiment” section that is meant to encourage children to immerse themselves in activities relating to the scientists’ areas of study. We believe that diversity in science is crucial for advancement, and therefore hope to inspire the next generation of scientists through immersion and representation.
ContributorsLane, Alison (Co-author) / Barton, Annmarie (Co-author) / Klemaszewski, James (Thesis director) / Fette, Donald (Committee member) / School of Molecular Sciences (Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
University College Groningen, in the Netherlands, is one of two Barrett Exchange programs. These programs allow for Barrett students to receive honors credit for their classes while studying abroad. While these programs are intriguing, there are no resources on the Barrett website that provide student accounts of the experiences. For the UCG exchange, there was only a link to the UCG website which was not extremely helpful for getting an understanding of what you will truly be getting yourself into while abroad. The solution that was decided upon was to create a vlog website for Barrett students to use as a resource when looking into the program. The site contains both person experiences from students, as well has helpful tips and tricks of how to maneuver your stay in the Netherlands. Overall, there were 8 videos created and 9 posts that can be used as resources for future Barrett students. The ‘Who are We?’, ‘Why a Barrett Exchange?’, ‘First Impressions and Adjusting to the Dutch Lifestyle’, and ‘Welcome Weeks’ posts contain testimony from two other Barrett students and myself who went on the exchange during the Fall, 2018 semester. The ‘Vistmarkt’ and ‘UCG Tour’ posts contain videos that show students places they will be able to venture to in the Netherlands. The ‘Travels Tips’ and ‘UCG Curriculum’ posts contain videos that have numerous tips for students who choose this exchange as their study abroad program they wish to participate in. The final post is called ‘Next Steps’ and it is meant for future students who wish to update and extend the knowledge that is presents on the website so that students can get the most up-to-date information. This website was created to give Barrett students a better understanding of the life-changing experience they are about to embark on.
ContributorsBarda, Taylor (Author) / Scott Lynch, Jacquelyn (Thesis director) / Chiu, Roland (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-12
Description
As a child passes through the birth canal, they become inoculated with vital gram positive and gram-negative bacteria, aerobes and anaerobes. Breast milk helps to support this growing microbiome by providing oligosaccharides that support its proliferation. Breast milk can be considered the most nutritious source of food available to a growing infant by providing the necessary nutrients, growth hormones and antibodies to promote digestive health, growth, and a strong immune system. The Developmental Origins of Health and Disease Theory (DOHaD) is a theory that suggests a growing fetus and nursing child's nutrients and immune system are dependent on the mother's exposure to nutrients and toxins. Studies have shown a positive correlation between the length of nursing and a child's overall health through life. In addition, consuming an enriched diet after weaning builds a strong immunological and nutritional basis from which the child can grow. This leads to improvements in a child's overall health, which has beneficial long-term effects on morbidity and mortality. This project applied the theory to two Middle Horizon (AD500-1100) individuals from Akapana, Tiwanaku, in the Lake Titicaca Basin, Bolivia. Stable nitrogen and carbon isotope analysis was applied to first molar serial samples of these two individuals to determine weaning age and early childhood diet. Both individuals were male; one male died in adolescence between the age of 9-15 years, and the other died as an elderly adult around the age of 50-59 years. The results showed that the male who died in adulthood was provisioned with supplemental and post-weaning foods high in animal protein, and received breast milk until around 37 months of age. The adolescent male was weaned between 11-12 months and consumed a diet dominated by C4 plants \u2014 most likely maize \u2014 with much less protein. The correlation between prolonged access to breast milk and a healthier and more nutritious childhood diet and longevity are consistent with the theory discussed above.
ContributorsCampbell, Sibella Sweelin (Author) / Knudson, Kelly (Thesis director) / Marsteller, Sara (Committee member) / Greenwald, Alexandra (Committee member) / School of Human Evolution & Social Change (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
The tarot is a means of communication with the world. It allows readers to interpret signs from their surroundings, gather information, and use this information to make inferences about a posed question. Its origins can be found in mid-15th century Europe as playing cards with four suits commonly used for gambling. Several hundred years later during the 18th century, it began to be used as a tool for divination; the Major Arcana, a set of 22 trump cards representing various archetypes, evolved as a supplement to a new tarot that has become associated with mysticism. The tarot’s foundation is based on archetypes that build society. It can serve as a visual lens to understand the experiences, thoughts, and actions of a person posing a question, allowing the reader to offer a solution by understanding and interpreting the specific visual language of a deck.
Hinduism is one of the oldest religions in the world and one of the most practiced today. It is full of fantastical myths and heroic legends, as well as undercurrents of feminism contrasted with misogyny and patriarchy. Hindu myths are contradictory as stories have evolved over time and have been retold with millions of differing perspectives.
In my thesis, I portrayed the 22 archetypes of the Major Arcana of the tarot through the lens of Hindu mythology as well as the broader pan-Indian culture. I include ancient stories and references to modern social issues. I visually communicated the connections between characters of Hindu mythology and the archetypes of the tarot with 22 watercolor paintings. This project was an opportunity to explore both the tarot through Hinduism, vice-versa. It allowed for the development of a deeper connection with spirituality and religion, along with a greater understanding of visual communication.
Hinduism is one of the oldest religions in the world and one of the most practiced today. It is full of fantastical myths and heroic legends, as well as undercurrents of feminism contrasted with misogyny and patriarchy. Hindu myths are contradictory as stories have evolved over time and have been retold with millions of differing perspectives.
In my thesis, I portrayed the 22 archetypes of the Major Arcana of the tarot through the lens of Hindu mythology as well as the broader pan-Indian culture. I include ancient stories and references to modern social issues. I visually communicated the connections between characters of Hindu mythology and the archetypes of the tarot with 22 watercolor paintings. This project was an opportunity to explore both the tarot through Hinduism, vice-versa. It allowed for the development of a deeper connection with spirituality and religion, along with a greater understanding of visual communication.
ContributorsHarve, Prathima (Author) / Jenik, Adriene (Thesis director) / Codell, Julie (Committee member) / Zirbel, Lisa (Committee member) / School of Molecular Sciences (Contributor) / School of Art (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Within our current educational infrastructure, there’s a lack of substantial preventive care knowledge present among elementary schoolchildren. With education cuts occurring statewide, many schools are left impoverished and schools are incapable of implementing various programs to benefit their local communities. This endeavor aims to visit public and charter elementary schools in the Phoenix Valley to educate youth regarding easily avoidable health risks by implementing healthy eating habits and exercise. Project BandAid will immerse students ages 7-9 in hands-on activities to enhance their knowledge on hygiene, healthy eating habits, and safety. This project incorporated funding from the Woodside Community Action Grant and Barrett, the Honors College as well as the help from Alpha Epsilon Delta (AED) volunteers.
ContributorsCovarrubias, Sidney Alicia (Co-author) / Kothari, Karishma (Co-author) / John, Benson (Co-author) / Fette, Donald (Thesis director) / Holechek, Susan (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / School of Molecular Sciences (Contributor) / School for the Future of Innovation in Society (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05