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An analysis of recent historical trends demonstrates that, while a large part of the twentieth century was dominated by a secular movement away from faith-based governance and societal norms, there exists now in the twenty-first century a developing global movement on the part of a burgeoning, international religious community to again find and clarify a place for faith in the public square. While much of the current international conversation revolves around the more radical elements of this movement, there is a more dominant mainstream, rational desire that is currently being overlooked and ignored, as modern, secular nation-states now grapple to balance freedom of religion and expression with a perceived constitutional and legal mandate to remain secular and neutral. This thesis will provide a study of the Republic of Kosovo as an example of such a conflict between the secular state and religious communities, highlighting its shift towards secularism, observing the religious community in Kosovo advocating for religious freedoms and a presence in the public sphere, and analyzing case law and social theory surrounding recent confrontations between this community and Kosovo's government and legal structure at large. The conclusion of this investigation will establish Kosovo as a local case study with global application, arguing that a misunderstanding of secularism to mean the crowding out of religion from the public sphere is an unsustainable approach for modern governments to take, and prescribing a model for equal representation and civil society that provides religious communities with opportunities to translate their values into more normative societal language with broad application.
ContributorsYentzer, Zachary Thomas (Author) / Batalden, Stephen (Thesis director) / Kader, David (Committee member) / Berisha, Shahin (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor)
Created2013-05
Description
This study was conducted as part of an underlying initiative to elucidate the mechanism of action of natural antibacterial clay minerals for application as therapeutic agents for difficult-to-treat infections such as methicillin-resistant Staphylococcus aureus (MRSA)-derived skin lesions and Buruli ulcer. The goal of this investigation was to determine whether exposure to the leachate of an antibacterial clay mineral, designated as CB, produced DNA double-strand breaks (DSBs) in Escherichia coli. A neutral comet assay for bacterial cells was adapted to assess DSB levels upon exposure to soluble antimicrobial compounds. Challenges involved with the adaptation process included comet visualization and data collection. To appropriately account for antimicrobial-mediated strand fragmentation, suitable control reactions comprised of exposures to water, ethanol, kanamycin, and bleomycin were developed and optimized for the assay. Bacterial exposure to CB resulted in significantly longer comet lengths compared to negative control exposures, suggesting that CB killing activity involves the induction of DNA DSBs. The results of this investigation further characterize the antimicrobial mechanisms associated with a particular clay mineral mixture. The adapted comet assay protocol described herein functions as an effective tool to assess double-strand fragmentation resulting from exposure to soluble antimicrobial compounds and to visually compare results from experimental and control reactions.
ContributorsSolanky, Dipesh (Author) / Haydel, Shelley (Thesis director) / Stout, Valerie (Committee member) / Adusumilli, Sarojini (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
“Recite (read)! In the name of your lord who has created all that exists” (1:96 Qur‟an). “Iqra” was the first word revealed to the Prophet of Islam (PBUH). The word “iqra” is an imperative verb in Arabic, and in the context of the verse it is commanding the Prophet (PBUH) to recite. This fact carries great significance as it was the first command given to the Muslims (Ibn Kathir). Muslims believe the Qur'an is in its original form and language, Arabic. Arabic is considered to be in inexhaustible language due to its vast vocabulary and root-based origin (Humza Yusuf). Each root is typically based on three letters, which are conjugated in different ways to creating individual words. Any word in the Qur'an can be traced back to a root word, thus enhancing the meaning of each carefully chosen phrase (Ibn Kathir). The word “al-Qur'an”, means, the book that is recited, therefore, it is fitting that the first verse revealed pertains to its recital. According to history the majority of civilizations were built off scripture or books. The Greeks had Homer, the Egyptians had hieroglyphics, the Christians had the Bible, and the Hebrews had the Torah. Interestingly enough, the Pre-Islamic Arabs were an ancient civilization with no book; the Qur'an was the first book in Arabic history. This was earthshattering for the Arabs of the time, as it was something new and went against the tradition, however, the revelation of the Qur'an proved to be the most influential occurrence in the Arab history. The Qur'an is a literary masterpiece, flaunting its superior style forming moving and powerful verses. The layout of the Qur'an is quite simple, as it contains thirty parts, called ajzaa (juz singular), which altogether make up 114 chapters, called surahs (Humza Yusuf). The beginning surahs are longer, and the verses are lengthy, while the latter surahs are much shorter and the verses are succinct and direct (Qur'an al Kareem). Each verse is known as an “ayah, ayaat (pl)” directly translated to mean a “sign” or a “miracle” in the Arabic language. There are over 6,600 ayaat in the Qur'an, ranging from some just one or two words, while others are hundreds of words. Each surah, has a general theme, and each surah is given at least one title, while a few surahs have more than one title (Humza Yusuf).
ContributorsShakoor, Momin (Author) / Ali, Souad T. (Thesis director) / Gallab, Abdullahi (Committee member) / Risha, Sarah (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
Glioblastoma multiforme (GBMs) is the most prevalent brain tumor type and causes approximately 40% of all non-metastic primary tumors in adult patients [1]. GBMs are malignant, grade-4 brain tumors, the most aggressive classication as established by the World Health Organization and are marked by their low survival rate; the median survival time is only twelve months from initial diagnosis: Patients who live more than three years are considered long-term survivors [2]. GBMs are highly invasive and their diffusive growth pattern makes it impossible to remove the tumors by surgery alone [3]. The purpose of this paper is to use individual patient data to parameterize a model of GBMs that allows for data on tumor growth and development to be captured on a clinically relevant time scale. Such an endeavor is the rst step to a clinically applicable predictions of GBMs. Previous research has yielded models that adequately represent the development of GBMs, but they have not attempted to follow specic patient cases through the entire tumor process. Using the model utilized by Kostelich et al. [4], I will attempt to redress this deciency. In doing so, I will improve upon a family of models that can be used to approximate the time of development and/or structure evolution in GBMs. The eventual goal is to incorporate Magnetic Resonance Imaging (MRI) data into a parameterized model of GBMs in such a way that it can be used clinically to predict tumor growth and behavior. Furthermore, I hope to come to a denitive conclusion as to the accuracy of the Koteslich et al. model throughout the development of GBMs tumors.
ContributorsManning, Miles (Author) / Kostelich, Eric (Thesis director) / Kuang, Yang (Committee member) / Preul, Mark (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12