Over the years, advances in research have continued to decrease the size of computers from the size of<br/>a room to a small device that could fit in one’s palm. However, if an application does not require extensive<br/>computation power nor accessories such as a screen, the corresponding machine could be microscopic,<br/>only a few nanometers big. Researchers at MIT have successfully created Syncells, which are micro-<br/>scale robots with limited computation power and memory that can communicate locally to achieve<br/>complex collective tasks. In order to control these Syncells for a desired outcome, they must each run a<br/>simple distributed algorithm. As they are only capable of local communication, Syncells cannot receive<br/>commands from a control center, so their algorithms cannot be centralized. In this work, we created a<br/>distributed algorithm that each Syncell can execute so that the system of Syncells is able to find and<br/>converge to a specific target within the environment. The most direct applications of this problem are in<br/>medicine. Such a system could be used as a safer alternative to invasive surgery or could be used to treat<br/>internal bleeding or tumors. We tested and analyzed our algorithm through simulation and visualization<br/>in Python. Overall, our algorithm successfully caused the system of particles to converge on a specific<br/>target present within the environment.

This thesis project is part of a larger collaboration documenting the history of the ASU Biodesign Clinical Testing Laboratory (ABCTL). There are many different aspects that need to be considered when transforming to a clinical testing laboratory. This includes the different types of tests performed in the laboratory. In addition to the diagnostic polymerase chain reaction (PCR) test that is performed detecting the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), antibody testing is also performed in clinical laboratories. Antibody testing is used to detect a previous infection. Antibodies are produced as part of the immune response against SARS-CoV-2. There are many different forms of antibody tests and their sensitives and specificities have been examined and reviewed in the literature. Antibody testing can be used to determine the seroprevalence of the disease which can inform policy decisions regarding public health strategies. The results from antibody testing can also be used for creating new therapeutics like vaccines. The ABCTL recognizes the shifting need of the community to begin testing for previous infections of SARS-CoV-2 and is developing new forms of antibody testing that can meet them.

In this project, I examined the relationship between lockdowns implemented by COVID-19 and the activity of animals in urban areas. I hypothesized that animals became more active in urban areas during COVID-19 quarantine than they were before and I wanted to see if my hypothesis could be researched through Twitter crowdsourcing. I began by collecting tweets using python code, but upon examining all data output from code-based searches, I concluded that it is quicker and more efficient to use the advanced search on Twitter website. Based on my research, I can neither confirm nor deny if the appearance of wild animals is due to the COVID-19 lockdowns. However, I was able to discover a correlational relationship between these two factors in some research cases. Although my findings are mixed with regard to my original hypothesis, the impact that this phenomenon had on society cannot be denied.

Actuaries can analyze healthcare trends to determine if rates are reasonable and if reserves are adequate. In this talk, we will provide a framework of methods to analyze the healthcare trend during the pandemic. COVID-19 may influence future healthcare cost trends in many ways. First, direct COVID-19 costs may increase the amount of total experienced healthcare costs. However, with the implementation of social distancing, the amount of regularly scheduled care may be deferred to a future date. There are also many unknown factors regarding the transmission of the virus. Implementing epidemiology models allows us to predict infections by studying the dynamics of the disease. The correlation between infection amounts and hospitalization occupancies provide a methodology to estimate the amount of deferred and recouped amounts of regularly scheduled healthcare costs. Thus, the combination of the models allows to model the healthcare cost trend impact due to COVID-19.

Optimal foraging theory provides a suite of tools that model the best way that an animal will <br/>structure its searching and processing decisions in uncertain environments. It has been <br/>successful characterizing real patterns of animal decision making, thereby providing insights<br/>into why animals behave the way they do. However, it does not speak to how animals make<br/>decisions that tend to be adaptive. Using simulation studies, prior work has shown empirically<br/>that a simple decision-making heuristic tends to produce prey-choice behaviors that, on <br/>average, match the predicted behaviors of optimal foraging theory. That heuristic chooses<br/>to spend time processing an encountered prey item if that prey item's marginal rate of<br/>caloric gain (in calories per unit of processing time) is greater than the forager's<br/>current long-term rate of accumulated caloric gain (in calories per unit of total searching<br/>and processing time). Although this heuristic may seem intuitive, a rigorous mathematical<br/>argument for why it tends to produce the theorized optimal foraging theory behavior has<br/>not been developed. In this thesis, an analytical argument is given for why this<br/>simple decision-making heuristic is expected to realize the optimal performance<br/>predicted by optimal foraging theory. This theoretical guarantee not only provides support<br/>for why such a heuristic might be favored by natural selection, but it also provides<br/>support for why such a heuristic might a reliable tool for decision-making in autonomous<br/>engineered agents moving through theatres of uncertain rewards. Ultimately, this simple<br/>decision-making heuristic may provide a recipe for reinforcement learning in small robots<br/>with little computational capabilities.

Dreadnought is a free-to-play multiplayer flight simulation in which two teams of 8 players each compete against one another to complete an objective. Each player controls a large-scale spaceship, various aspects of which can be customized to improve a player’s performance in a game. One such aspect is Officer Briefings, which are passive abilities that grant ships additional capabilities. Two of these Briefings, known as Retaliator and Get My Good Side, have strong synergy when used together, which has led to the Dreadnought community’s claiming that the Briefings are too powerful and should be rebalanced to be more in line with the power levels of other Briefings. This study collected gameplay data with and without the use of these specific Officer Briefings to determine the precise impact on gameplay. Linear correlation matrices and inference on two means were used to determine performance impact. It was found that, although these Officer Briefings do improve an individual player’s performance in a game, they do not have a consistent impact on the player’s team performance, and that these Officer Briefings are therefore not in need of rebalancing.