On March 11th, COVID-19 was declared a pandemic by the World Health Organization. The ensuing months saw an extensive allocation of resources toward combating the virus and the development of a vaccine. Despite extensive research on SARS-CoV-2, there remains little information regarding the implications of SARS-CoV-2 gastrointestinal shedding on COVID-19 disease. It is hypothesized that SARS-CoV-2 RNA is shed in the stool for up to several weeks and that viral protein persists in the GI tract. This study also explored calprotectin and zonulin levels, markers of inflammation, and intestinal permeability, respectively, to assess if increased viral shedding is associated with elevated levels of either. This study utilized RT-qPCR assays to confirm the presence of viral RNA. Subsequently, RT-qPCR positive samples were heat-inactivated and SARS-CoV-2 spike detection enzyme-linked immunosorbent assay (ELISA) was used to ascertain viral protein shedding. Additional ELISA was performed to assess zonulin and calprotectin levels. Results indicated that 30 of the 758 unique samples were confirmed SARS-CoV-2 positive by RT-qPCR. Spike protein was ultimately not detected by ELISA. Additionally, no significant increase in zonulin was observed in patient samples when comparing RT-qPCR positive and negative Samples. A notable upwards trend approaching significance in calprotectin levels existed for patients who tested positive for SARS-CoV-2 by RT-qPCR, though, it was found that no correlation existed between SARS-CoV-2 copy number and calprotectin levels. Understanding the interaction between SARS-CoV-2 and the GI tract may therefore have significant clinical implications and this study demonstrates the need for additional studies to garner a more comprehensive understanding.

The purpose of this study is to investigate the role of health misinformation and the lack of credible health information as determinants of health disparities affecting the Hispanic population in the United States during public health emergencies. Using the COVID-19 pandemic as a quintessential and relevant exhibit of a public health emergency, a review of literature was conducted to identify the interactions between the accessibility of health misinformation and credible health information in exacerbating pre-existing socio-economic barriers that affect the Hispanic population. The findings of this study were then analyzed to develop solutions for future public health emergencies to ensure that vulnerable communities are provided equally accurate and accessible health information as non-vulnerable communities in order to promote a more effective nationwide public health response. These solutions include providing more educational resources to help vulnerable communities find accurate information online and increasing surveillance of misinformation sources online, especially in the Spanish language.

In January of 2020, the first cases of COVID-19 were recorded in the United States with one of them being an Arizona State University student. Since these initial cases, over 2.4 million more cases have been recorded in Arizona alone. As of March of 2020, Arizona State University Ambulatory Health Services moved to adjust their healthcare delivery methods in response to the COVID-19 pandemic. We aim to identify areas of ASU Ambulatory Health Services as of March of 2020 that need improvement based on an anonymous survey carried out among ASU students, faculty, and staff. The survey was created through Survey Monkey and consisted of 20 questions about the participant’s experience with ASU’s Ambulatory Health Services; while the survey was being created, a literature review was being conducted concerning ASU’s health care delivery in the past and the health care delivery in the greater Maricopa County region. The overall consensus of the 54 participants who took the survey was that approximately 55% of participants had an overall very satisfactory experience through ASU Ambulatory Health Services with a net promoter score of 87% satisfaction and approximately 47% of participants were very likely to recommend ASU Ambulatory Health Services with a net promoter score of about 79%. Most participants reported overall satisfactory experiences but when asked for further commentary they provided more specific criticisms of their experience that could be improved. The specific frustrations that were mentioned were issues with insurance, lack of awareness with available services, instructions on updated regulations and scheduling, and issues with patients’ visits being logged into their medical records. We recommend that ASU Ambulatory Health Services improve in these areas highlighted by the survey answers; as most of these issues are results from communication issues between ASU Ambulatory Health Services and the public, we suggest better means of communication between the public and the health services.

In January of 2020, the first cases of COVID-19 were recorded in the United States with one of them being an Arizona State University student. Since these initial cases, over 2.4 million more cases have been recorded in Arizona alone. As of March of 2020, Arizona State University Ambulatory Health Services moved to adjust their healthcare delivery methods in response to the COVID-19 pandemic. We aim to identify areas of ASU Ambulatory Health Services as of March of 2020 that need improvement based on an anonymous survey carried out among ASU students, faculty, and staff. The survey was created through Survey Monkey and consisted of 20 questions about the participant’s experience with ASU’s Ambulatory Health Services; while the survey was being created, a literature review was being conducted concerning ASU’s health care delivery in the past and the health care delivery in the greater Maricopa County region. The overall consensus of the 54 participants who took the survey was that approximately 55% of participants had an overall very satisfactory experience through ASU Ambulatory Health Services with a net promoter score of 87% satisfaction and approximately 47% of participants were very likely to recommend ASU Ambulatory Health Services with a net promoter score of about 79%. Most participants reported overall satisfactory experiences but when asked for further commentary they provided more specific criticisms of their experience that could be improved. The specific frustrations that were mentioned were issues with insurance, lack of awareness with available services, instructions on updated regulations and scheduling, and issues with patients’ visits being logged into their medical records. We recommend that ASU Ambulatory Health Services improve in these areas highlighted by the survey answers; as most of these issues are results from communication issues between ASU Ambulatory Health Services and the public, we suggest better means of communication between the public and the health services.

For our thesis, we analyzed a set of data from the on-going longitudinal study, “Aging In the Time of COVID-19” (Guest et al., ongoing) from the Center for Innovation in Healthy and Resilient Aging at Arizona State University. This study researched how COVID-19 and the resulting physical/social distancing impacted aging individuals' health, wellbeing, and quality-of-life. The survey collected data regarding over 1400 participants’ social connections, health, and experiences during COVID-19. This study gathered information about participants’ comorbid conditions, age, sex, location, etc. We presented this work in the form of a website including the traditional elements of an Honors Thesis as well as a visual essay with the data analysis portion coded with the JavaScript library D3 and a list of resources for our target audience, older adults who are experiencing social isolation and/or loneliness.