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With the number of internationally-run clinical drug trials increasing, the double standards between those in developed nations and those in developing nations are being scrutinized under the ethical microscope. Many argue that several pharmaceutical companies and researchers are exploiting developing nation participants. Two issues of concern are the use of

With the number of internationally-run clinical drug trials increasing, the double standards between those in developed nations and those in developing nations are being scrutinized under the ethical microscope. Many argue that several pharmaceutical companies and researchers are exploiting developing nation participants. Two issues of concern are the use of a placebo control when an effective alternative treatment exists and the lack of drug availability to the country that hosted the clinical trial should the experimental drug prove effective. Though intuitively this seems like an instance of exploitation, philosophically, exploitation theories cannot adequately account for the wrongdoing in these cases. My project has two parts. First, after explaining why the theories of Alan Wertheimer, John Lawrence Hill, and Ruth Sample fail to explain the exploitation in clinical drug research, I provide an alternative account of exploitation that can explain why the double standard in clinical research is harmful. Rather than craft a single theory encompassing all instances of exploitation, I offer an account of a type, or subset, of exploitation that I refer to as comparative exploitation. The double standards in clinical research fall under the category of comparative exploitation. Furthermore, while many critics maintain that cases of comparative exploitation, including clinical research, are mutually beneficial, they are actually harmful to its victims. I explain the harm of comparative exploitation using Ben Bradley's counterfactual account of harm and Larry May's theory of sharing responsibility. The second part of my project focuses on the "standard of care" argument, which most defenders use to justify the double standard in clinical research. I elaborate on Ruth Macklin's position that advocates of the "standard of care" position make three faulty assumptions: placebo-controlled trials are the gold standard, the only relevant question responsive to the host country's health needs is "Is the experimental product being studied better than the 'nothing' now available to the population?", and the only way of obtaining affordable products is to test cheap alternatives to replace the expensive ones. In the end, I advocate moving towards a universalizing of standards in order to avoid exploitation.
ContributorsFundora, Danielle (Author) / McGregor, Joan (Thesis advisor) / Brake, Elizabeth (Committee member) / Portmore, Douglas (Committee member) / Arizona State University (Publisher)
Created2013
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Principles of climate mitigation in environmental ethics often draw on either considerations of fairness and forward-looking concerns, or on justice and backward-looking concerns. That is, according to some theorists, considerations of the current distribution of climate benefits and burdens are foremost, while others take repairing historic wrongs as paramount. Some

Principles of climate mitigation in environmental ethics often draw on either considerations of fairness and forward-looking concerns, or on justice and backward-looking concerns. That is, according to some theorists, considerations of the current distribution of climate benefits and burdens are foremost, while others take repairing historic wrongs as paramount. Some theorists integrate considerations of fairness and justice to formulate hybrid climate principles. Such an integrative approach is promising particularly in the context of environmental harm to indigenous subsistence peoples, who are among those suffering the most from climate change. I argue that existing integrative climate principles tend not to sufficiently emphasize considerations of backward-looking justice. This is a problem for indigenous peoples seeking reparations for environmental harm and violations of their human rights. Specifically, indigenous people in the Arctic suffer a cultural harm from climate change as they lose their land, and their way of life, to erosion, cementing their status as climate refugees. I argue that the current climate situation facing Native Arctic people is unfair according to Rawls' second principle of justice. In addition, the situation is unjust as indigenous people suffer from emissions by others and few attempts are made for reparations. Thus, Rawlsian fairness combined with reparative justice provide a befitting theoretical framework. I conclude that an acceptable climate principle will adequately integrate considerations of both fairness and justice, both forward-looking and backward-looking considerations.
ContributorsSweetland, Lauren (Author) / Brake, Elizabeth (Thesis advisor) / Tsosie, Rebecca (Committee member) / Portmore, Douglas (Committee member) / Arizona State University (Publisher)
Created2014
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This paper examines the strength of a recent argument made against democracy. The notion of epistocracy, a system of government where the wise or the knowers rule, has garnered some attention of late. These theories of epistocracy have traditionally struggled with questions of political legitimacy and authority. In Against Democracy,

This paper examines the strength of a recent argument made against democracy. The notion of epistocracy, a system of government where the wise or the knowers rule, has garnered some attention of late. These theories of epistocracy have traditionally struggled with questions of political legitimacy and authority. In Against Democracy, Jason Brennan articulates an alternative theory for epistocracy which may prove more promising. Brennan argues instead that democracy faces objections of political legitimacy which epistocracy avoids because democracy either harms or violates rights as a result of granting political power to the incompetent. This negative argument against democracy hopes to make epistocracy the preferable option in comparison. I will argue, however, that if we take this comparative approach then we ought to prefer democracy---or, rather, democratic reform---over epistocracy as the best solution in addressing the concerns which Brennan raises. It is not enough to merely point to flaws in democracy. For this argument to be successful, it must also be shown that epistocracy avoids those flaws at an acceptable cost. I claim that, upon examination, epistocratic theories fail to make this case. Rather, it is evident from this examination that there are various institutional mechanisms available with which democracy may manage the risks and harms which might arise from imbuing the incompetent with political power. This in turn suggests ways by which we might reform democracy to achieve similar results hoped for by epistocrats without the effort, risk, and cost of tearing down and rebuilding our fundamental political institutions.
ContributorsZhang, Alexander (Author) / Brake, Elizabeth (Thesis advisor) / Portmore, Douglas (Committee member) / Calhoun, Cheshire (Committee member) / Arizona State University (Publisher)
Created2018
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In their criticism of various approaches to upbringing and related American family law jurisprudence, liberal theorists tend to underweight the interests of parents in directing the development of children’s values. Considered through the lens of T.M. Scanlon’s contractualism, providing a good upbringing is not a matter of identifying children’s “best

In their criticism of various approaches to upbringing and related American family law jurisprudence, liberal theorists tend to underweight the interests of parents in directing the development of children’s values. Considered through the lens of T.M. Scanlon’s contractualism, providing a good upbringing is not a matter of identifying children’s “best interests” or acting in accordance with overriding end-state principles. Rather, children should be raised in accordance with principles for the general regulation of behavior that no one could reasonably reject as a basis for informed, unforced general agreement. The process of ascertaining such principles requires an understanding of relevant values; a good upbringing is what children receive when parents properly value their children, enabling them to appropriately recognize what it is that they have reason to do given the roles that they play. By developing the account of upbringing hinted at in Scanlon’s contractualist monograph, What We Owe to Each Other, this project identifies and responds to some common mistakes in contemporary liberal theorizing on childhood, suggests that contractualism yields a more plausible account of upbringing than alternative approaches, and along the way identifies some implications of contractualism for public policy where individuals properly value the children of others in their community.
ContributorsPike, Kenneth (Author) / de Marneffe, Peter (Thesis advisor) / Calhoun, Cheshire (Committee member) / Brake, Elizabeth (Committee member) / Arizona State University (Publisher)
Created2019
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Joseph Rotblat (1908-2005) was the only physicist to leave the Manhattan Project for moral reasons before its completion. He would spend the rest of his life advocating for nuclear disarmament. His activities for disarmament resulted in the formation, in 1957, of the Pugwash conferences, which emerged as the leading global

Joseph Rotblat (1908-2005) was the only physicist to leave the Manhattan Project for moral reasons before its completion. He would spend the rest of his life advocating for nuclear disarmament. His activities for disarmament resulted in the formation, in 1957, of the Pugwash conferences, which emerged as the leading global forum to advance limits on nuclear weapons during the Cold War. Rotblat's efforts, and the activities of Pugwash, resulted in both being awarded the Nobel Peace Prize in 1995. Rotblat is a central figure in the global history of resistance to the spread of nuclear weapons. He also was an important figure in the emergence, after World War II, of a counter-movement to introduce new social justifications for scientific research and new models for ethics and professionalism among scientists. Rotblat embodies the power of the individual scientist to say "no" and thus, at least individually, put limits of conscience on his or her scientific activity. This paper explores the political and ethical choices scientists make as part of their effort to behave responsibly and to influence the outcomes of their work. By analyzing three phases of Rotblat's life, I demonstrate how he pursued his ideal of beneficial science, or science that appears to benefit humanity. The three phases are: (1) his decision to leave the Manhattan Project in 1944, (2) his role in the creation of Pugwash in 1957 and his role in the rise of the organization into international prominence and (3) his winning the Nobel Peace Prize in 1995. These three phases of Rotblat's life provide a singular window of the history of nuclear weapons and the international movement for scientific responsibility in the 50 years since the bombing of Hiroshima in 1945. While this paper does not provide a complete picture of Rotblat's life and times, I argue that his experiences shed important light on the difficult question of the individual responsibility of scientists.
ContributorsEvans, Alison Dawn (Author) / Zachary, Gregg (Thesis director) / Hurlbut, Ben (Committee member) / Francis, Sybil (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2015-05
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We live in a world of inequality. Some thrive and live luxurious lives while others are deprived of the most basic necessities. With such extreme differences the question is raised, what is our moral obligation to help others? I will examine two theories, Peter Singer's utilitarian theory and Michael Slote's

We live in a world of inequality. Some thrive and live luxurious lives while others are deprived of the most basic necessities. With such extreme differences the question is raised, what is our moral obligation to help others? I will examine two theories, Peter Singer's utilitarian theory and Michael Slote's care ethical approach, both of which outline humankind's moral obligation to help others. I will argue that Slote's approach to tackling this complex question is superior to Singer's approach, because it is more palatable and embraces human nature. I will then suggest a strategy to synthesize the two concepts, resulting in global and personal moral elevation.
ContributorsMoore, Ashley Nicole (Author) / Brake, Elizabeth (Thesis director) / Botham, Thad (Committee member) / Barrett, The Honors College (Contributor) / WPC Graduate Programs (Contributor) / W. P. Carey School of Business (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / School of Accountancy (Contributor)
Created2015-05
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This thesis aims to address the ethics of keeping the big cats, such as lions, tigers, and leopards, in zoos. It is a practice that has generated some controversy in light of scientific studies reporting stress among wide-ranging animals in captive enclosures, as well as in the context of wider

This thesis aims to address the ethics of keeping the big cats, such as lions, tigers, and leopards, in zoos. It is a practice that has generated some controversy in light of scientific studies reporting stress among wide-ranging animals in captive enclosures, as well as in the context of wider discussions in animal welfare and conservation ethics in zoos. A driving question for this project, therefore, was "What are the arguments for and against keeping large felids in zoos/captivity?" This thesis examines the historical and current ethical approaches to evaluating the ethics of maintaining big cats in zoos. Due to many of the big cat species listed as endangered species on the IUCN redlist, the species-centered approach to zoo ethics is becoming the common viewpoint, and, as a result, zoos are deemed ethical because of their contribution to ex situ conservation practices. Further, the ethical arguments against zoos are minimized when the zoos provide suitable and appropriate enclosures for their large felids. Of course, not all zoos are created equal; the ethics of zoos need to be evaluated on a case-by-case basis, but in general, it is ethical to maintain big cats in zoos.
ContributorsZeien, Krista Marie (Author) / Minteer, Ben (Thesis director) / Smith, Andrew (Committee member) / Ellison, Karin (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Romania is in the midst of an identity emergency due to its relatively recent departure from a communist dictatorship. This paper will take a look at identities within Romania while paying close attention to the way that emerging political, economic, religious and gender identities have been and are being used

Romania is in the midst of an identity emergency due to its relatively recent departure from a communist dictatorship. This paper will take a look at identities within Romania while paying close attention to the way that emerging political, economic, religious and gender identities have been and are being used to oppress the Romanian queer population. This paper seeks to justify an application of Western values towards the call for enfranchisement of Romanian queers. Western values, in this sense, will be based on Enlightenment notions of equality in all people and based on philosophers whose writings and paradigms are centered in the Western world. Furthermore, it will discuss violence and masculinity in hopes that understanding and critically examining these topics may be used in application towards the emerging Romanian identities and statistics which highlight and implicate queer oppression. Again, this paper will not seek to definitely link as causal any one emerging identity towards the oppression of the queer minority in Romania nor will it seek to undermine any single Romanian institution, but rather question the correlative elements of Romanian society that may be implicated in potential oppression, violences, and a neglect of the Romanian queer minority.
ContributorsWoodmansee, Jon Wessley (Author) / Montesano, Mark (Thesis director) / Brake, Elizabeth (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor)
Created2014-05
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The prospect of anti-aging or life extension technology is controversial in biogerentology but deemed even by skeptical experts to warrant discussion. I discuss the justifications that the probability of life extension technology being developed in the near future is reasonably high and that this research justifies the time and money

The prospect of anti-aging or life extension technology is controversial in biogerentology but deemed even by skeptical experts to warrant discussion. I discuss the justifications that the probability of life extension technology being developed in the near future is reasonably high and that this research justifies the time and money it receives. I investigate potential ethical and societal issues anti-aging technology might create. This paper addresses inequality of access, economic cost, changes in quality of life, the role of death in human life, if and how the technology should be regulated and how parties who choose not to undergo treatment can be fairly treated, even when they are a minority.
Created2015-05
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Perhaps the most common and forceful criticism directed at absolutist deontological theories is that they allow for the occurrence of morally catastrophic events whenever such events could only and certainly be prevented by the violation of a deontological constraint. Some deontologists simply bite the bullet, accept this implication of their

Perhaps the most common and forceful criticism directed at absolutist deontological theories is that they allow for the occurrence of morally catastrophic events whenever such events could only and certainly be prevented by the violation of a deontological constraint. Some deontologists simply bite the bullet, accept this implication of their theory, and give their best arguments as to why it does not undermine absolutism. Others, I think more plausibly, opt for an alternative deontological theory known as ‘moderate deontology’ and are thereby able to evade the criticism since moderate deontology permits violations of constraints under certain extreme circumstances. The goal of this thesis is to provide a defense of moderate deontology against three worries about the view, namely, that it is more accurately interpreted as a kind of pluralism than as a deontology, that there is no non-arbitrary way of setting thresholds for deontological constraints, and that the positing of thresholds for constraints would lead to some problematic results in practice. I will respond to each of these worries in turn. In particular, I will argue that moderate deontology is properly understood as a deontological theory despite its partial concern for consequentialist considerations, that thresholds for deontological constraints can be successfully located without arbitrariness by democratic appeal to people’s commonsense moral intuitions, and that the alleged problematic results of positing thresholds for constraints can be effectively explained away by the moderate deontologist.
ContributorsCook, Tyler Blake (Author) / Calhoun, Cheshire (Thesis advisor) / Portmore, Douglas (Committee member) / Brake, Elizabeth (Committee member) / Arizona State University (Publisher)
Created2017