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The inherent risk in testing drugs has been hotly debated since the government first started regulating the drug industry in the early 1900s. Who can assume the risks associated with trying new pharmaceuticals is unclear when looked at through society's lens. In the mid twentieth century, the US Food and

The inherent risk in testing drugs has been hotly debated since the government first started regulating the drug industry in the early 1900s. Who can assume the risks associated with trying new pharmaceuticals is unclear when looked at through society's lens. In the mid twentieth century, the US Food and Drug Administration (FDA) published several guidance documents encouraging researchers to exclude women from early clinical drug research. The motivation to publish those documents and the subsequent guidance documents in which the FDA and other regulatory offices established their standpoints on women in drug research may have been connected to current events at the time. The problem of whether women should be involved in drug research is a question of who can assume risk and who is responsible for disseminating what specific kinds of information. The problem tends to be framed as one that juxtaposes the health of women and fetuses and sets their health as in opposition. That opposition, coupled with the inherent uncertainty in testing drugs, provides for a complex set of issues surrounding consent and access to information.
ContributorsMeek, Caroline Jane (Author) / Maienschein, Jane (Thesis director) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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While there is extensive information available about organizations that receive donated organs for transplant, much less is known about those that accept tissue and whole bodies for medical education and research. Throughout the United States, nontransplant anatomical donation organizations exist within an ambiguous sector of the donation industry, unencumbered by

While there is extensive information available about organizations that receive donated organs for transplant, much less is known about those that accept tissue and whole bodies for medical education and research. Throughout the United States, nontransplant anatomical donation organizations exist within an ambiguous sector of the donation industry, unencumbered by federal regulations. Although these companies adhere to the Uniform Anatomical Gift Act, the lack of a single entity responsible for overseeing their operations has led to public skepticism and animosity among competing businesses. Legislation has the potential to legitimize the industry. For it to be successful, however, the intricacies of a complex market that deals directly with the movement of human remains and intangible issues of human integrity and morality, must be thoroughly understood.
ContributorsGlynn, Emily Sanders (Author) / Brian, Jennifer (Thesis director) / Fisher, Rebecca (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / Department of English (Contributor)
Created2015-05
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Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder that is becoming increasingly common. Autism does not yet have a known etiology, nor a definitive diagnostic test, thus making diagnosis a difficult and rarely uniform task. Currently, ASD is behaviorally diagnosed based on criteria defined by the American Psychiatric Association

Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder that is becoming increasingly common. Autism does not yet have a known etiology, nor a definitive diagnostic test, thus making diagnosis a difficult and rarely uniform task. Currently, ASD is behaviorally diagnosed based on criteria defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders (DSM). Recently, a change was made in the criteria from more lenient criteria in DSM-IV-TR, to more narrow criteria laid out by the DSM-V, which supersedes the DSM-IV-TR. This drastic change raised many questions and debates about which set of criteria are better. The more lenient criteria offers a more inclusive diagnosis giving greater access to therapies; while the narrow diagnostic criteria excludes some individuals, creating a more uniform diagnosis that's easier to use in research. This thesis analyzes the change in diagnostic criteria from the DSM-IV-TR to the DSM-V and the effects of these changes on the practices of diagnosis. In addition, it explores the implications of this change for the families of children with autism and for those involved in autism research, examining their respective opinions and interests pertaining to narrow verses broad diagnostic criteria. Building on this analysis, the thesis offers recommendations about diagnostic criteria should be set. It argues that the wellbeing of patients takes priority over the interests of researchers, and thus diagnosis should be done in a way that offers the best prognosis for all children who suffer from autistic symptoms.
ContributorsBremer, Michelle Nichole (Author) / Hurlbut, Ben (Thesis director) / Robert, Jason (Committee member) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Lithium ion batteries are quintessential components of modern life. They are used to power smart devices — phones, tablets, laptops, and are rapidly becoming major elements in the automotive industry. Demand projections for lithium are skyrocketing with production struggling to keep up pace. This drive is due mostly to the

Lithium ion batteries are quintessential components of modern life. They are used to power smart devices — phones, tablets, laptops, and are rapidly becoming major elements in the automotive industry. Demand projections for lithium are skyrocketing with production struggling to keep up pace. This drive is due mostly to the rapid adoption of electric vehicles; sales of electric vehicles in 2020 are more than double what they were only a year prior. With such staggering growth it is important to understand how lithium is sourced and what that means for the environment. Will production even be capable of meeting the demand as more industries make use of this valuable element? How will the environmental impact of lithium affect growth? This thesis attempts to answer these questions as the world looks to a decade of rapid growth for lithium ion batteries.

ContributorsMelton, John (Author) / Brian, Jennifer (Thesis director) / Karwat, Darshawn (Committee member) / Chemical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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When an individual is conceived there is a metaphorical roll of the dice. A game of chance is played with their genetics to which they cannot consent. Unlucky players could have inherited mild conditions such as chronic allergies to terrible diseases such as Cystic Fibrosis or Tay-Sachs. Controlling the genetics

When an individual is conceived there is a metaphorical roll of the dice. A game of chance is played with their genetics to which they cannot consent. Unlucky players could have inherited mild conditions such as chronic allergies to terrible diseases such as Cystic Fibrosis or Tay-Sachs. Controlling the genetics of an individual through the use of gene editing technology could be the key to ending this cycle of genetic diseases. Once detrimental diseases are now being cured through direct applications of genetic engineering. Even as we see the uses of genetic engineering technologies change the world, the more “sci-fi” applications have yet to be fully realized or explored. Editing hereditary genes before birth may have the ability to eliminate diseases from entire genetic lines, reduce the possibility for certain cancers and diseases, and perhaps even modify phenotypes in humans to create enhanced humans. Although this scientific field shows promise, it does have its reservations. Like any other scientific field, its ability to benefit humanity depends on its use.
ContributorsSchuler, Jacob (Co-author) / Silva, Anthony (Co-author) / Brian, Jennifer (Thesis director) / Ross, Christian (Committee member) / Harrington Bioengineering Program (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace inequality as well as encourage these institutions to adopt more equitable policies. By rating companies based on what truly matters to women, ASU’s Difference Engine hopes to help both women in existing career paths as well as women seeking a new career or position in companies. However, in order for the WPI to become a relevant scoring metric of gender equality within the workplace, we must raise awareness about the issue of gender equality and of the index itself. By raising awareness about gender inequality as well as inspiring companies to further equality within their workplaces, the WPI will serve to have an integral role in increasing gender equality in the workplace. Our approach for raising awareness utilizes two different strategies: (1) establishing a new version of the WPI website that is both informative and aesthetically pleasing and (2) generating social media content on TikTok that appeal to a variety of audiences and introduce them to the WPI and our mission.
ContributorsThomas, Elisa (Author) / Tieu, Lienna (Co-author) / Howard, Brooke (Co-author) / Zaffar, Ehsan (Thesis director) / Gel, Esma (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor) / School of Politics and Global Studies (Contributor) / Division of Teacher Preparation (Contributor) / Sanford School of Social and Family Dynamics (Contributor)
Created2022-05
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Description

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace inequality as well as encourage these institutions to adopt more equitable policies. By rating companies based on what truly matters to women, ASU’s Difference Engine hopes to help both women in existing career paths as well as women seeking a new career or position in companies. However, in order for the WPI to become a relevant scoring metric of gender equality within the workplace, we must raise awareness about the issue of gender equality and of the index itself. By raising awareness about gender inequality as well as inspiring companies to further equality within their workplaces, the WPI will serve to have an integral role in increasing gender equality in the workplace. Our approach for raising awareness utilizes two different strategies: (1) establishing a new version of the WPI website that is both informative and aesthetically pleasing and (2) generating social media content on TikTok that appeal to a variety of audiences and introduce them to the WPI and our mission.

ContributorsThomas, Elisa (Author) / Tieu, Lienna (Co-author) / Howard, Brooke (Co-author) / Zaffar, Ehsan (Thesis director) / Gel, Esma (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor)
Created2022-05
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Description

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace inequality as well as encourage these institutions to adopt more equitable policies. By rating companies based on what truly matters to women, ASU’s Difference Engine hopes to help both women in existing career paths as well as women seeking a new career or position in companies. However, in order for the WPI to become a relevant scoring metric of gender equality within the workplace, we must raise awareness about the issue of gender equality and of the index itself. By raising awareness about gender inequality as well as inspiring companies to further equality within their workplaces, the WPI will serve to have an integral role in increasing gender equality in the workplace. Our approach for raising awareness utilizes two different strategies: (1) establishing a new version of the WPI website that is both informative and aesthetically pleasing and (2) generating social media content on TikTok that appeal to a variety of audiences and introduce them to the WPI and our mission.

ContributorsThomas, Elisa (Author) / Tieu, Lienna (Co-author) / Howard, Brooke (Co-author) / Zaffar, Ehsan (Thesis director) / Gel, Esma (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor)
Created2022-05
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Description

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace inequality as well as encourage these institutions to adopt more equitable policies. By rating companies based on what truly matters to women, ASU’s Difference Engine hopes to help both women in existing career paths as well as women seeking a new career or position in companies. However, in order for the WPI to become a relevant scoring metric of gender equality within the workplace, we must raise awareness about the issue of gender equality and of the index itself. By raising awareness about gender inequality as well as inspiring companies to further equality within their workplaces, the WPI will serve to have an integral role in increasing gender equality in the workplace. Our approach for raising awareness utilizes two different strategies: (1) establishing a new version of the WPI website that is both informative and aesthetically pleasing and (2) generating social media content on TikTok that appeal to a variety of audiences and introduce them to the WPI and our mission.

ContributorsThomas, Elisa (Author) / Tieu, Lienna (Co-author) / Howard, Brooke (Co-author) / Zaffar, Ehsan (Thesis director) / Gel, Esma (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor)
Created2022-05
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Description

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace

The Difference Engine at Arizona State University developed the Women’s Power and Influence Index (WPI) in order to combat the systemic inequality faced by women in the workplace. It aims to analyze data, such as Equal Employment Opportunity data, from various Fortune 500 companies to provide a measure of workplace inequality as well as encourage these institutions to adopt more equitable policies. By rating companies based on what truly matters to women, ASU’s Difference Engine hopes to help both women in existing career paths as well as women seeking a new career or position in companies. However, in order for the WPI to become a relevant scoring metric of gender equality within the workplace, we must raise awareness about the issue of gender equality and of the index itself. By raising awareness about gender inequality as well as inspiring companies to further equality within their workplaces, the WPI will serve to have an integral role in increasing gender equality in the workplace. Our approach for raising awareness utilizes two different strategies: (1) establishing a new version of the WPI website that is both informative and aesthetically pleasing and (2) generating social media content on TikTok that appeal to a variety of audiences and introduce them to the WPI and our mission.

ContributorsThomas, Elisa (Author) / Tieu, Lienna (Co-author) / Howard, Brooke (Co-author) / Zaffar, Ehsan (Thesis director) / Gel, Esma (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor)
Created2022-05