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The intent of this thesis was to explore current literature to further understand the work environments of medical fields and the obstacles that are unique to women pursuing medical careers. It is acknowledged that a significant glass ceiling exists for women in medical fields, specifically areas such as academia and

The intent of this thesis was to explore current literature to further understand the work environments of medical fields and the obstacles that are unique to women pursuing medical careers. It is acknowledged that a significant glass ceiling exists for women in medical fields, specifically areas such as academia and surgery. Thus, the research is focused on determining explanations for a lack of women in said medical specialties, as well as understanding the source of the obstacles women face in medicine. This study was designed to obtain a general background from a literature review and then, to compare and supplement the findings with in-depth interviews of females in a variety of medical careers. From the literature review and the interviews, it was confirmed that the largest area of inequality women in medical fields faced was struggling to balance work and personal life, specifically motherhood. Furthermore, the knowledge gained from the literature review and interviews provided a framework for suggesting possible solutions to help women successfully balance a professional medical career and a personal life.
ContributorsHaugen, Kelsey Blair (Author) / Fonow, Mary Margaret (Thesis director) / Scheiner, Georganne (Committee member) / McGibbney, Michelle (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2013-05
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Identifying disease biomarkers may aid in the early detection of breast cancer and improve patient outcomes. Recent evidence suggests that tumors are immunogenic and therefore patients may launch an autoantibody response to tumor associated antigens. Single-chain variable fragments of autoantibodies derived from regional lymph node B cells of breast cancer

Identifying disease biomarkers may aid in the early detection of breast cancer and improve patient outcomes. Recent evidence suggests that tumors are immunogenic and therefore patients may launch an autoantibody response to tumor associated antigens. Single-chain variable fragments of autoantibodies derived from regional lymph node B cells of breast cancer patients were used to discover these tumor associated biomarkers on protein microarrays. Six candidate biomarkers were discovered from 22 heavy chain-only variable region antibody fragments screened. Validation tests are necessary to confirm the tumorgenicity of these antigens. However, the use of single-chain variable autoantibody fragments presents a novel platform for diagnostics and cancer therapeutics.
ContributorsSharman, M. Camila (Author) / Magee, Dewey (Mitch) (Thesis director) / Wallstrom, Garrick (Committee member) / Petritis, Brianne (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor) / Virginia G. Piper Center for Personalized Diagnostics (Contributor) / Biodesign Institute (Contributor)
Created2012-12
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Time spent alone is a topic that has been studied in great detail, particularly the manner in which it is spent and the effect it has during the adolescent stage of life. Similarly, stress levels in adolescents have always been a topic of interest because of the effects they could

Time spent alone is a topic that has been studied in great detail, particularly the manner in which it is spent and the effect it has during the adolescent stage of life. Similarly, stress levels in adolescents have always been a topic of interest because of the effects they could have on the individual later in adulthood. Oddly enough however, the two areas of study have never been looked at in relation to one another. This study will look at different types of alone time as possible stressors in a community sample (N=82) of adolescents transitioning to college. The data on time alone and stress levels was collected through diary reports over a period of 3 days. The analysis only yielded significant effects for females and only for specific categories. It was found that females experience the lowest amount of perceived stress when they are alone and want to be alone, they have more negative affect when their desired environment differs from their current situation, and more positive affect in both the alone incongruence and not alone congruence situations. These results indicate that only women experience stress and affect changes when they encounter different congruent and incongruent environments.
ContributorsVanderwerf, Jennifer (Author) / Doane, Leah (Thesis director) / Knight, George (Committee member) / Arbona, P. Anita (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Parenting magazines within the U.S. have long been a source of comfort and information for parents. As evidenced by subscription numbers in the millions, parents’ desire for ‘expert’ advice on all aspects of child rearing make them prime consumers for the magazine industry. One study found that when parents seek

Parenting magazines within the U.S. have long been a source of comfort and information for parents. As evidenced by subscription numbers in the millions, parents’ desire for ‘expert’ advice on all aspects of child rearing make them prime consumers for the magazine industry. One study found that when parents seek advice, parenting magazines were second only to friends as a resource, and were consulted more often than professional resources such as doctors or health organizations (Koepke & Williams, 1989). Ultimately, the images and concepts parents retain from their exposure to parenting magazines are conveyed (explicitly or implicitly) to their children. At its very core, gender scripts serve as an institutionalized form of social control, or as Bem believes, “a basic organizing principle for every human culture” (1981). Further, researchers have elaborated, “gender inequalities and sex stereotypes hurt the majority of individuals by limiting their range of experiences, and thus their growth” (Spees & Zimmerman, 2002). This provides an absolute disservice to individuals and to our communities two fold, as gendered messages in parenting magazines can shape (or indeed limit) the experiences and perceptions of both parents and their children. The intention of this study is to examine the ways in which editorial content in Parents magazine has the potential to influence parents’ perception of gender in relation to their children and child rearing practices. It also seeks to explore how these gender messages have changed over the last ten years, as well as what these messages may be communicating to parents about their children. I aim to frame this discussion within a condensed review of literature that supports the importance and influence of parenting magazines in recent history. I will also consider how early on children display an understanding of gender and a few of the many ways gender typing may affect them in childhood and beyond. In this thesis, I approach this issue through the theory of socialization, in which I argue the magazine’s gender messages are communicated to parents, who then convey these messages to their children during childhood. However, this study acknowledges the importance of observing an issue from multiple standpoints and I believe that further research on this topic should be done from both a socialization and a social construction viewpoint. I will then critically analyze, through a feminist theoretical framework, gender implications found among the images and some of the accompanying text in Parents magazine in 2002 and 2012. Through this thesis, I argue that Parents magazine, through its editorial content, provides some unique spaces in which gender equality can be furthered, while it has also become more stereotyped and restricted within other areas in the last ten years.
ContributorsSheldon, Jessica (Author) / Scheiner, Georganne (Thesis director) / McGibbney, Michelle (Committee member) / Katsulis, Yasmina (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
The purpose of my honors thesis project was to generate the tools needed for in vivo imaging by determining the optimal plasmid-fluorophore combination. To determine the optimal plasmid and fluorophore, asd plasmids were constructed with various promoters, origins of replications, and red fluorophores. The optimal asd plasmid for fluorescent in

The purpose of my honors thesis project was to generate the tools needed for in vivo imaging by determining the optimal plasmid-fluorophore combination. To determine the optimal plasmid and fluorophore, asd plasmids were constructed with various promoters, origins of replications, and red fluorophores. The optimal asd plasmid for fluorescent in vivo imaging was determined by the plasmid stability, growth rate, and growth phase dependence on fluorescent intensity. The end goal is to be able to use the asd plasmid in vaccine strains for the purpose of in vivo imaging of the recombinant attenuated Salmonella vaccine (RASV).
ContributorsEudy, L. Adam (Author) / Curtiss, Roy (Thesis director) / Roland, Kenneth (Committee member) / Forbes, Stephen (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12